Research Topics
| Luciano BernardiSummaryAffiliation: University of Pavia Country: Italy Publications
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Detail Information
Publications
Breathing patterns and cardiovascular autonomic modulation during hypoxia induced by simulated altitudeL Bernardi
Department of Internal Medicine, University of Pavia and IRCCS S. Matteo, Italy
J Hypertens 19:947-58. 2001..CONCLUSIONS: Well-performed slow yogic breathing maintains better blood oxygenation without increasing VE (i.e. seems to be a more efficient breathing) and reduces sympathetic activation during altitude-induced hypoxia...
Interaction between central-peripheral chemoreflexes and cerebro-cardiovascular controlLucia Spicuzza
Dept. of Internal Medicine, University of Catania, Italy
Clin Auton Res 15:373-81. 2005..Increased sympathetic activity (and reduced baroreflex sensitivity) is one of the mechanisms by which hypoxia stimulates cardiac sympathetic activity...
Reduced hypoxic ventilatory response with preserved blood oxygenation in yoga trainees and Himalayan Buddhist monks at altitude: evidence of a different adaptive strategy?Luciano Bernardi
Department of Internal Medicine, University of Pavia and IRCCS Ospedale S Matteo, Pavia, Italy
Eur J Appl Physiol 99:511-8. 2007..Respiratory adaptations induced by the practice of yoga may represent an efficient strategy to cope with altitude-induced hypoxia...
New method to measure and improve consistency of baroreflex sensitivity valuesLuciano Bernardi
Department of Internal Medicine, Pavia University, Pavia, Italy
Clin Auton Res 20:353-61. 2010..In addition, we tested whether high-pass filtering of data, by removing slow non-baroreflex-mediated fluctuations, could improve the agreement between different BRS methods...
Respiratory and cerebrovascular responses to hypoxia and hypercapnia in familial dysautonomiaLuciano Bernardi
New York University Medical Center, New York University School of Medicine, New York, USA
Am J Respir Crit Care Med 167:141-9. 2003..Higher resting BP delays occurrence of syncope during hypoxia. Therapeutic measures preventing hypoxia/hypocapnia may correct cardiovascular accidents in patients with FD...
Widespread cardiovascular autonomic dysfunction in primary amyloidosis: does spontaneous hyperventilation have a compensatory role against postural hypotension?L Bernardi
Department of Internal Medicine, IRCCS S Matteo and University of Pavia, Pavia, Italy
Heart 88:615-21. 2002..To investigate the possible causes of abnormal blood pressure control in light chain related (primary, AL) amyloidosis...
Ventilation, autonomic function, sleep and erythropoietin. Chronic mountain sickness of Andean nativesLuciano Bernardi
Clinica Medica 2, IRCCS S Matteo, University of Pavia, Italy
Adv Exp Med Biol 543:161-75. 2003..Improving oxygenation can represent a possible therapeutic option for this syndrome...
Cardiorespiratory interactions to external stimuliL Bernardi
Dipartimento di Medicina Interna, IRCCS S Matteo and University of Pavia, Italy
Arch Ital Biol 143:215-21. 2005....
Cardiovascular, cerebrovascular, and respiratory changes induced by different types of music in musicians and non-musicians: the importance of silenceL Bernardi
Department of Internal Medicine, IRCCS S Matteo, University of Pavia, Pavia, Italy
Heart 92:445-52. 2006....
Hypoxic ventilatory response in successful extreme altitude climbersL Bernardi
Dept of Internal Medicine, Universita di Pavia IRCCS Ospedale S Matteo, 27100 Pavia, Italy
Eur Respir J 27:165-71. 2006..A less sensitive hypoxic response and a greater ventilatory efficiency might increase ventilatory reserve and allow sustainable ventilation in the extreme hypoxia at the summit...
Arterial baroreflex modulation influences postural swayLuciano Bernardi
Department of Internal Medicine, Clinica Medica 2, University of Pavia, IRCCS S Matteo, 27100, Pavia, Italy
Clin Auton Res 21:151-60. 2011..To test this hypothesis, we used a pure motion-independent autonomic stimulus (neck suction) to modulate the carotid baroreceptors on a broad frequency range, distinct from that of respiration...
Effects of physical training on cardiovascular control after heart transplantationLuciano Bernardi
Department of Internal Medicine, IRCCS Policlinico S Matteo, University of Pavia, Italy
Int J Cardiol 118:356-62. 2007..We tested the effects of physical training on baroreceptors-mediated control of heart rate and blood pressure in recently heart-transplanted subjects...
Autonomic and cerebrovascular abnormalities in mild COPD are worsened by chronic smokingL Bernardi
Dept of Internal Medicine, University of Pavia and IRCCS Hospital San Matteo, Pavia, Italy
Eur Respir J 32:1458-65. 2008..All abnormalities can be partly corrected by improving the cardio- and cerebrovascular autonomic modulation, suggesting that functional autonomic abnormalities are already present at an early stage of disease...
Dynamic interactions between musical, cardiovascular, and cerebral rhythms in humansLuciano Bernardi
Department of Internal Medicine, Pavia University and IRCCS S Matteo, Pavia, Italy
Circulation 119:3171-80. 2009..We tested whether compositions characterized by variable emphasis could produce parallel instantaneous cardiovascular/respiratory responses and whether these changes mirrored music profiles...
Slow breathing increases arterial baroreflex sensitivity in patients with chronic heart failureLuciano Bernardi
Department of Internal Medicine, University of Pavia and IRCCS Ospedale S Matteo, Pavia, Italy
Circulation 105:143-5. 2002..It is well established that a depressed baroreflex sensitivity may adversely influence the prognosis in patients with chronic heart failure (CHF) and in those with previous myocardial infarction...
Heart rate and cardiovascular variability at high altitudeLuciano Bernardi
Department of Internal Medicine, University of Pavia, Italy
Conf Proc IEEE Eng Med Biol Soc 2007:6679-81. 2007....
Slow breathing reduces chemoreflex response to hypoxia and hypercapnia, and increases baroreflex sensitivityL Bernardi
Department of Internal Medicine, University of Pavia and IRCCS Ospedale S Matteo, Pavia, Italy
J Hypertens 19:2221-9. 2001..To investigate whether breathing more slowly modifies the sensitivity of the chemoreflex and baroreflex...
Modulatory effects of respirationL Bernardi
Dipartimento di Medicina Interna, University of Pavia, Italy
Auton Neurosci 90:47-56. 2001..This opens a new area of future research in the better management of patients with cardiovascular autonomic dysfunction...
[Autonomic nervous system adaptation during physical exercise]L Bernardi
Dipartimento di Medicina Interna, Universita degli Studi, Pavia
Ital Heart J Suppl 2:831-9. 2001..In the present review these aspects and the effects of physical training on the autonomic nervous system are examined in normal subjects and in patients with heart failure...
Slow breathing improves arterial baroreflex sensitivity and decreases blood pressure in essential hypertensionChacko N Joseph
Department of Internal Medicine, University of Pavia, IRCCS Ospedale S. Matteo, Pavia, Italy
Hypertension 46:714-8. 2005..001 versus controls). Slow breathing reduces blood pressure and enhances baroreflex sensitivity in hypertensive patients. These effects appear potentially beneficial in the management of hypertension...
Persistence of baroreceptor control of cerebral blood flow velocity at a simulated altitude of 5000 mClaudio Passino
Department of Internal Medicine, University of Pavia and IRCCS S Matteo, Pavia, and Department of Internal Medicine, Unita Ospedaliera S Maria Nuova, Firenze, Italy
J Hypertens 25:1862-70. 2007..To assess the effects of acute exposure to simulated high altitude on baroreflex control of mean cerebral blood flow velocity (MCFV)...
Non-respiratory components of heart rate variability in heart transplant recipients: evidence of autonomic reinnervation?L Bernardi
Dipartimento di Medicina Interna, Sezione Clinica Medica I, Pavia, Italy
Clin Sci (Lond) 86:537-45. 1994..94). The slopes obtained in these heart transplant recipients were comparable (although of lower values) with those obtained in control subjects.(ABSTRACT TRUNCATED AT 250 WORDS)..
Effect of rosary prayer and yoga mantras on autonomic cardiovascular rhythms: comparative studyL Bernardi
Dipartimento di Medicina Interna, University of Pavia, 27100 Pavia, Italy
BMJ 323:1446-9. 2001..To test whether rhythmic formulas such as the rosary and yoga mantras can synchronise and reinforce inherent cardiovascular rhythms and modify baroreflex sensitivity...
Influence of type of surgery on the occurrence of parasympathetic reinnervation after cardiac transplantationL Bernardi
Department of Internal Medicine, University of Pavia and IRCCS S Matteo, Italy
Circulation 97:1368-74. 1998..Standard surgical techniques leave many parasympathetic branches intact in the original atria and thus with less stimulus to reinnervate the donor atria...
Effect of breathing rate on oxygen saturation and exercise performance in chronic heart failureL Bernardi
Department of Internal Medicine, IRCCS S Matteo, University of Pavia, Italy
Lancet 351:1308-11. 1998..In chronic heart failure (CHF), impaired pulmonary function can independently contribute to oxygen desaturation and reduced physical activity. We investigated the effect of breathing rate on oxygen saturation and other respiratory indices...
Influence of respiratory instability during neurocardiogenic presyncope on cerebrovascular and cardiovascular dynamicsC Porta
Department of Internal Medicine, University of Pavia and IRCCS Ospedale S Matteo, Pavia, Italy
Heart 94:1433-9. 2008..To analyse the influence of breathing activity on cerebrovascular dynamics during presyncope...
[Interaction between respiration, autonomic function, and respiratory pattern in heart failure. New possibilities of rehabilitation intervention]C Porta
Dipartimtento di Medicina Interna, , Pavia
Ital Heart J Suppl 2:624-7. 2001....
Respiratory and cardiovascular adaptations to progressive hypoxia; effect of interval hypoxic trainingL Bernardi
IRCCS S Matteo and Department of Internal Medicine, University of Pavia, Pavia, Italy
Eur Heart J 22:879-86. 2001..Interval hypoxic training was proposed as a technique for adapting hypoxia of various origins. Its effects on the hypoxic ventilatory response and on cardiovascular autonomic control are unknown...
Acute haemodynamic effects of ibopamine and dopamine on isovolumic relaxationL Bernardi
Department of Internal Medicine, University of Pavia, IRCCS, San Matteo, Italy
Eur J Pharmacol 164:415-24. 1989..Ibopamine and epinine therefore significantly improved the isovolumic relaxation phase, like dopamine, without however affecting the heart rate...
Contribution of the dynamic phonocardiography to the valvular heart disease diagnosis: an expert system studyM Piepoli
Department of Internal Medicine, University of Pavia, Italy
Acta Cardiol 45:521-7. 1990..In 198 valvular heart disease patients, the use of dynamic tests significantly improved the rate of diagnostic success, thus confirming the usefulness of dynamic phono-mechanocardiography...
Noninvasive assessment of the relationship between cardiac and autonomic function in diabetesA M Grandi
Department of Internal Medicine, I R C C S Policlinico San Matteo, University of Pavia, Italy
Acta Cardiol 47:77-85. 1992..Latent abnormalities of left ventricular function can be unmasked by acute haemodynamic challenges such as handgrip, and are correlated with abnormalities in autonomic function tests...
Cardiovascular variability is/is not an index of autonomic control of circulationLuciano Bernardi
J Appl Physiol 101:686; author reply 690-1. 2006
Sinusoidal neck suction for evaluation of baroreflex sensitivity during desflurane and sevoflurane anesthesiaCornelius Keyl
Department of Anesthesiology, University of Regensburg, Germany
Anesth Analg 95:1629-36, table of contents. 2002..IMPLICATIONS: Despite exhibiting different effects on autonomic activity, sevoflurane and desflurane depress the baroreflex-mediated short-term control of heart rate and blood pressure in a similar manner...
Autonomic modulation of heart rate during obstructive versus central apneas in patients with sleep-disordered breathingLucia Spicuzza
Istituto di Malattie Respiratorie, Via Passo Gravina 187, 95125 Catania, Italy
Am J Respir Crit Care Med 167:902-10. 2003..0001), whereas the LF component remained unchanged. These results show markedly different autonomic alterations during and after OA versus CA, suggesting a surge in sympathetic modulation after the obstructive episodes...
Gene expression in the Andes; relevance to neurology at sea levelOtto Appenzeller
New Mexico Health Enhancement and Marathon Clinics Research Foundation, 361, Big Horn Ridge, NE Albuquerque 87122 1424, USA
J Neurol Sci 207:37-41. 2003..VEGF-165 expression suggests that it contributes to preservation of neuronal function in human chronic hypoxia. VHL mutations may mark those destined to develop neural crest tumors which are common in the Andes...
Effects of unilateral and bilateral carotid baroreflex stimulation on cardiac and neural sympathetic discharge oscillatory patternsRaffaello Furlan
Unità Sincopi e Disturbi della Postura, Medicina Interna II, Ospedale L Sacco, Universita di Milano, Via G B Grassi 74, 20157 Milano, Italy
Circulation 108:717-23. 2003..We tested the hypothesis that unilateral carotid baroreceptor perturbation might differentially affect HR, AP, and MSNA variability compared with stimulation of the opposite side...
Consensus statement on chronic and subacute high altitude diseasesFabiola Leon-Velarde
Cayetano Heredia University IIA, Department of Biological and Physiological Sciences, Oxygen Transport Laboratory, Lima 100, Peru
High Alt Med Biol 6:147-57. 2005..Most of the cases of high altitude diseases are preventable if on-site personnel identify the condition and implement appropriate care...
Frequency-dependent baroreflex control of blood pressure and heart rate during physical exerciseGiammario Spadacini
Dipartimento di Medicina Interna IRCCS S Matteo and University of Pavia, Italy
Int J Cardiol 107:171-9. 2006..We hypothesised that this uncertainty arose from the differing responses of the vagus (fast) and sympathetic (slow) arms of the autonomic effectors, and to differing sympatho-vagal balance at different exercise intensities...
Effect of treatment with nasal continuous positive airway pressure on ventilatory response to hypoxia and hypercapnia in patients with sleep apnea syndromeLucia Spicuzza
Dipartimento di Medicina Interna e Medicina Specialistica, Sezione di Malattie Respiratorie, Universita di Catania, Catania, Italy
Chest 130:774-9. 2006..Nasal CPAP (nCPAP) is an effective treatment for OSA, but little is known on its effect on chemoreflex sensitivity...
Music and the heart. Interview by Emma BainesLuciano Bernardi
Circulation 116:f139-40. 2007
How to assess arterial compliance in humansGianfranco Parati
J Hypertens 24:1009-12. 2006
