Research Topics
| Salvatore BenvengaSummaryAffiliation: University of Bologna Country: Italy Publications
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Detail Information
Publications
Euthyroid hyperthyrotropinemia secondary to hyperestrogenemia in a male with congenital adrenal hyperplasiaS Benvenga
Cattedra e Divisione di Endocrinologia, University of Messina School of Medicine, Messina, Italy
Horm Metab Res 32:321-5. 2000....- Heterogeneity of the thyroglobulin epitopes associated with circulating thyroid hormone autoantibodies in hashimoto's thyroiditis and non-autoimmune thyroid diseasesS Benvenga
Section of Endocrinology, Clinical and Experimental Department of Medicine and Pharmacology, University of Messina School of Medicine, Messina, Italy
J Endocrinol Invest 25:977-82. 2002..In light of recent data in the literature, we further suggest that the responsible epitopes are more likely to be expressed in leaked TG fragments, rather than leaked intact TG... - Changed presentation of Hashimoto's thyroiditis in North-Eastern Sicily and Calabria (Southern Italy) based on a 31-year experienceSalvatore Benvenga
Sezione di Endocrinologia del Dipartimento Clinico Sperimentale di Medicina e Farmacologia, University of Messina, Messina, Italy
Thyroid 18:429-41. 2008..To quantify the yearly prevalence of Hashimoto's thyroiditis at our Division and evaluate changes in its clinical presentation over the period 1975-2005... - Altered intestinal absorption of L-thyroxine caused by coffeeSalvatore Benvenga
Sezione di Endocrinologia del Dipartimento Clinico Sperimentale di Medicina e Farmacologia, Universita di Messina, Messina, Italy
Thyroid 18:293-301. 2008..To report eight case histories, and in vivo and in vitro studies showing coffee's potential to impair thyroxine (T4) intestinal absorption... - Effects of L-carnitine on thyroid hormone metabolism and on physical exercise toleranceS Benvenga
Sezione di Endocrinologia del Dipartimento Clinico Sperimentale di Medicina e Farmacologia, University of Messina School of Medicine, 98125 Messina, Italy
Horm Metab Res 37:566-71. 2005..CARN was also shown to modulate thyroid hormone action in peripheral tissues, the most frequent modulation observed being inhibition... - Human thyroid autoantigens and proteins of Yersinia and Borrelia share amino acid sequence homology that includes binding motifs to HLA-DR molecules and T-cell receptorSalvatore Benvenga
Sezione di Endocrinologia del Dipartimento Clinico Sperimentale di Medicina e Farmacologia, Universita di Messina, Messina, Italy
Thyroid 16:225-36. 2006..In conclusion, our in silico data do not directly demonstrate that Borrelia and Yersinia proteins trigger AITD but suggest that a restricted number of them might have the potential to, at least in persons with certain HLA-DR alleles... - Brain injury and hypopituitarism: the historical backgroundSalvatore Benvenga
Dipartimento Clinico Sperimentale di Medicina e Farmacologia Sezione di Endocrinologia, Programma di Endocrinologia Molecolare Clinica, AOU Policlinico Gaetano Martino, Universita di Messina, Messina, Italy
Pituitary 8:193-5. 2005..The interest triggered by the latest review, which concluded that PHTH was indeed less rare than commonly believed, was such that a total of 192 cases have been reported from year 2000 through April, 2005... - Effects of carnitine on thyroid hormone actionSalvatore Benvenga
Sezione di Endocrinologia, Dipartimento Clinico Sperimentale di Medicina e Farmacologia, University of Messina School of Medicine, 98125 Messina, Italy
Ann N Y Acad Sci 1033:158-67. 2004..Since hyperthyroidism impoverishes the tissue deposits of carnitine, there is a rationale for using L-carnitine at least in certain clinical settings... - Homologies between proteins of Borrelia burgdorferi and thyroid autoantigensSalvatore Benvenga
Sezione di Endocrinologia del Dipartimento Clinico Sperimentale di Medicina e Farmacologia, Universita di Messina, Messina, Italy
Thyroid 14:964-6. 2004..Our data strengthen the hypothesis of Bb and YE as environmental triggers of AITD in genetically predisposed persons through molecular mimicry mechanisms... - Central hormonal regulation and dimorphism of arousalS Benvenga
Sezione di Endocrinologia del Dipartimento Clinico Sperimentale di Medicina e Farmacologia, Universita di Messina, and Programma Dip di Endocrinologia Molecolare Clinica, A O U Policlinico Gaetano Martino, Messina, Italy
Int J Androl 28:18-22. 2005..A number of excitatory and inhibitory signals modulate the activity of certain brain structures. Scientists have begun to test some of these chemicals or their synthetic analogues/antagonists in humans... - High-density lipoprotein-facilitated entry of thyroid hormones into cells: a mechanism different from the low-density lipoprotein-facilitated entrySalvatore Benvenga
Sezione di Endocrinologia, Dipartimento Clinico Sperimentale di Medicina e Farmacologia, University of Messina School of Medicine, Policlinico Universitario, Messina, Italy
Thyroid 12:547-56. 2002..This effect of HDL represents facilitated diffusion of TH through the cell membrane... - Usefulness of L-carnitine, a naturally occurring peripheral antagonist of thyroid hormone action, in iatrogenic hyperthyroidism: a randomized, double-blind, placebo-controlled clinical trialS Benvenga
Cattedra and Sezione di Endocrinologia, Dipartimento Clinico Sperimentale di Medicina e Farmacologia, University of Messina School of Medicine, 98125 Messina, Italy
J Clin Endocrinol Metab 86:3579-94. 2001..Because hyperthyroidism depletes the body deposits of carnitine and since carnitine has no toxicity, teratogenicity, contraindications and interactions with drugs, carnitine can be of clinical use... - Gender differences in locomotor and stereotypic behavior associated with l-carnitine treatment in miceSalvatore Benvenga
Sezione di Endocrinologia, Dipartimento Clinico Sperimentale di Medicina e Farmacologia, dell Adolescenza e della Donna, Universita di Messina, Messina, Italy
Gend Med 8:1-13. 2011..The carnitines exert neuroprotective and neuromodulatory actions, and carnitine supplementation increases locomotor activity (LMA) in experimental animals... - Thyroxine binding to members and non-members of the serine protease inhibitor familyS Benvenga
Department of Clinical and Experimental Medicine and Pharmacology, University of Messina School of Medicine, Italy
J Endocrinol Invest 25:32-8. 2002..Some, but not all, of these alpha-globulins belong to the same superfamily of TBG and also bind steroid hormones... - Re-evaluation of the thyroxine binding to human plasma lipoproteins using three techniquesS Benvenga
Clinical Experimental Department of Medicine and Pharmacology, University of Messina, Italy
J Endocrinol Invest 24:RC16-8. 2001..Hence, the anti-atherosclerotic effects of T4 resulting from binding to the LDL should be greater than anticipated based on GFC data... - Carnitine is a naturally occurring inhibitor of thyroid hormone nuclear uptakeS Benvenga
Cattedra di Endocrinologia, University of Messina, School of Medicine, Italy
Thyroid 10:1043-50. 2000..Our data are consistent with carnitine being a peripheral antagonist of TH action, and they indicate a site of inhibition at or before the nuclear envelope... - Myxedema coma of both primary and secondary origin, with non-classic presentation and extremely elevated creatine kinaseS Benvenga
Cattedra e Divisione di Endocrinologia, University of Messina, School of Medicine, Italy
Horm Metab Res 32:364-6. 2000..In addition, cardiac problems as those of our patient should not discourage from substitutive treatment (using L-thyroxine and the gastrointestinal route of absorption), if the age is relatively low... - Detection of circulating autoantibodies against thyroid hormones in an infant with permanent congenital hypothyroidism and her twin with transient congenital hypothyroidism: possible contribution of thyroid hormone autoantibodies to neonatal and infant hySalvatore Benvenga
Sezione di Endocrinologia, Dipartimento Clinico Sperimentale di Medicina e Farmacologia, Policlinico Universitario di Messina, Italy
J Pediatr Endocrinol Metab 21:1011-20. 2008..THAb may contribute to the induction of hypothyroidism in neonates and infants, especially those with underlying autoimmune thyroid disease... - Apoptosis and apoptosis-related proteins in thyroid myopathiesMaria C Monici
Clinica Neurologia 2, Department of Neurosciences, Psychiatry and Anaesthesiology, Policlinico Universitario, 98125 Messina, Italy
Muscle Nerve 26:383-8. 2002..By contrast, Fas antigen was overexpressed in hyperthyroid myopathy, correlating with low TSH levels. These findings suggest an anti-apoptotic role for TSH itself in skeletal muscle... - Parathyroid carcinoma presenting as normocalcemic hyperparathyroidismAlfredo Campenni
Unità di Medicina Nucleare, Dipartimento di Scienze Radiologiche, Padiglione E, piano terra, Policlinico Universitario G Martino, University of Messina, V Consolare Valeria, 98125, Messina, Italy
J Bone Miner Metab 30:367-72. 2012..Moreover, Ki-67 expression and AgNOR analysis confirmed their additional value in complementing the histological evaluation of a parathyroid malignant mass... - Spontaneous recovery from isolated post-traumatic central hypogonadism in a womanRosaria M Ruggeri
Clinical Experimental Department of Medicine and Pharmacology, Section of Endocrinology, Policlinico Universitario G Martino, University of Messina, Messina, Italy
Hormones (Athens) 9:332-7. 2010..Hypopituitarism is a recognized complication of Traumatic Brain Injury (TBI). Resolution of established anterior pituitary hormones deficiency is rare... - Thyroid metastases from renal cell carcinoma: review of the literatureAlessandro Sindoni
University of Messina, Italy
ScientificWorldJournal 10:590-602. 2010..Finally, survival was longer for women. Thyroid metastases, even if rare in the clinical practice, must be considered in the differential diagnosis of a thyroid nodule, particularly in patients who have a history of malignancies... - Severe head trauma in patients with unexplained central hypothyroidismSalvatore Benvenga
Sezione di Endocrinologia del Dipartimento Clinico Sperimentale di Medicina e Farmacologia, University of Messina School of Medicine, Policlinico Universitario di Messina, Messina, Italy
Am J Med 116:767-71. 2004 - Cross-reactivity of Anisakis simplex: possible role of Ani s 2 and Ani s 3Fabrizio Guarneri
Istituto di Dermatologia, Policlinico Gaetano Martino, Universita di Messina, Messina, Italy
Int J Dermatol 46:146-50. 2007..To date, only four allergens of A. simplex have been characterized, but their role in cross-reactivity is largely unknown... - A patient with stress-related onset and exacerbations of Graves diseaseRoberto Vita
Department of Pathology and Experimental Microbiology, University of Messina, Messina, Italy
Nat Clin Pract Endocrinol Metab 5:55-61. 2009..Diagnostic work-up disclosed an avid radioactive iodine uptake by the goiter. On ultrasound examination, the thyroid gland was enlarged with a diffusely hypoechogenic structure and intense vascularization... - Association of lichen sclerosus and autoimmune thyroiditis: possible role of Borrelia burgdorferi?Mario Vaccaro
Institute of Dermatology, University of Messina, Messina, Italy
Thyroid 12:1147-8. 2002 - Update on thyroid cancerS Benvenga
Programma di Endocrinologia Molecolare Clinica, AOU Policlinico G Martino, Messina, Italy
Horm Metab Res 40:323-8. 2008.... - Supra-acetabular brown tumor due to primary hyperparathyroidism associated with chronic renal failureRosaria M Ruggeri
Department of Clinical Experimental Medicine and Pharmacology, University of Messina, Messina, Italy
ScientificWorldJournal 10:799-805. 2010.... - Environmental factors and genetic background that interact to cause autoimmune thyroid diseaseFabrizio Guarneri
Istituto di Dermatologia, Policlinico Gaetano Martino, Messina, Italy
Curr Opin Endocrinol Diabetes Obes 14:398-409. 2007..To provide an updated list of genetic and environmental causative factors of autoimmune thyroid disease, and report about the recent discoveries concerning their interaction in the pathogenesis of thyroid autoimmunity... - Thyroid hormone autoantibodies in primary Sjögren syndrome and rheumatoid arthritis are more prevalent than in autoimmune thyroid disease, becoming progressively more frequent in these diseasesR M Ruggeri
Clinical Experimental Department of Medicine and Pharmacology, University of Messina, School of Medicine, Policlinico Universitario, Italy
J Endocrinol Invest 25:447-54. 2002.... - Dysregulation of secretion of CXC alpha-chemokine CXCL10 in papillary thyroid cancer: modulation by peroxisome proliferator-activated receptor-gamma agonistsAlessandro Antonelli
Department of Internal Medicine, School of Medicine, University of Pisa, Pisa, Italy
Endocr Relat Cancer 16:1299-311. 2009..Moreover, TZDs inhibited CXCL10 secretion in TFC and stimulated it in PTCs. The effect of TZDs on CXCL10 was unrelated to the significant antiproliferative effect in PTCs... - Multifocal motor neuropathy and asymptomatic Hashimoto's thyroiditis: first report of an associationAntonio Toscano
Department of Neuroscience, Psychiatry and Anesthesiology, University of Messina, Via C Valeria, 98125, Messina, Italy
Neuromuscul Disord 12:566-8. 2002..This case also suggests to deeply investigate the thyroid function in patients with multifocal motor neuropathy... - Clinico-pathological significance of cell-type-specific loss of heterozygosity on chromosome 7q21: analysis of 318 microdissected thyroid lesionsMaria Trovato
Dipartimento di Patologia Umana, Policlinico Universitario, Messina, Italy
Endocr Relat Cancer 11:365-76. 2004..2, in the same position where the common fragile site FRA7E was previously mapped. LOH at this locus represents an early event in the development of follicular TC and is associated with intense growth of thyroid glands... - Germline mutation of von Hippel-Lindau (VHL) gene 695 G>A (R161Q) in a patient with a peculiar phenotype with type 2C VHL syndromeLibero Santarpia
Sezione di Endocrinologia del Dipartimento Clinico Sperimentale di Medicina e Farmacologia Policlinico Universitario, Messina, I-98125, Italy
Ann N Y Acad Sci 1073:198-202. 2006..We describe a Sicilian girl with type 2C VHL who showed the apparently de novo mutation R161Q in association with an extra-axial supratentorial frontal meningioma, which can be included as a characteristic sign in VHL... - Acromegaly and coronary disease: an integrated evaluation of conventional coronary risk factors and coronary calcifications detected by computed tomographySalvatore Cannavo
Sezione di Endocrinologia, Pad H, piano 4 Azienda Ospedaliera Universitaria Policlinico G Martino, Via Consolare Valeria 1, 98125 Messina, Italy
J Clin Endocrinol Metab 91:3766-72. 2006..At autopsy, it was demonstrated in about 20% of patients with long-lasting disease, and myocardial infarction was reported as cause of death in a quarter of acromegalics... - Serum thyroid autoantibodies in patients with idiopathic either acute or chronic urticariaS Gangemi
Operative Unit and School Allergology and Clinical Immunology, Department of Human Pathology, University of Messina, Messina, Italy
J Endocrinol Invest 32:107-10. 2009..6%) positiveness for at least one type of ATA in CIU is greater than that of 6 representative international studies published between the years 2000 and 2006 (111/488 or 22.7%, range 15-29%, chi2=4.884, p=0.027)... - Bilateral cyclic cheek lesions related to premenstrual syndrome: a multifactorial pathogenesis?Paola Lucia Minciullo
Department of Human Pathology, University of Messina, Italy
Arch Gynecol Obstet 279:927-9. 2009..Cheek biting is a chronic, usually innocuous, self-inflicted injury that often occurs as a parafunctional habit... - Thyroid metastasis of clear cell renal carcinoma: Report of a caseMassimo Rizzo
Department of Human Pathology, Laboratory of Diagnostic Cytology, Section of Medical Oncology, University of Messina, Messina, Italy
Diagn Cytopathol 37:759-62. 2009.... - Expression of CD30 ligand and CD30 receptor in normal thyroid and benign and malignant thyroid nodulesM Trovato
Dipartimento di Patologia Umana, University of Messina, School of Medicine, Italy
Thyroid 11:621-8. 2001..In conclusion, CD30L/CD30 signaling is activated only past the colloid nodule stage, most frequently in an autocrine fashion... - Co-expression of interleukin-6 (IL-6) and interleukin-6 receptor (IL-6R) in thyroid nodules is associated with co-expression of CD30 ligand/CD30 receptorR M Ruggeri
Section of Endocrinology, Clinical Experimental Department of Medicine and Pharmacology, University of Messina School of Medicine, Messina, Italy
J Endocrinol Invest 25:959-66. 2002..In the normal thyroid tissue, colloid nodules, and another subset of benign and malignant thyroid nodules, IL-6 expression is under control of signals other than CD30L/CD30... - Serum hepatocyte growth factor is increased in Hashimoto's thyroiditis whether or not it is associated with nodular goiter as compared with healthy non-goitrous individualsR M Ruggeri
Unit of Endocrinology, Clinical Experimental Department of Medicine and Pharmacology, University of Messina, Messina, Italy
J Endocrinol Invest 32:465-9. 2009..Some growth factors and cytokines are known to cooperate with TSH in thyroid nodular growth, but few data are available on their circulating levels in Hashimoto's thyroiditis (HT)... - Thyroid metastases from clear cell renal carcinoma 18 years after nephrectomyA Sindoni
Department of Radiological Sciences, Unit of Nuclear Medicine, University of Messina, Messina, Italy
Ann Endocrinol (Paris) 71:127-30. 2010..As a corollary, follow-up of such patients should include periodic thyroid exploration or at least a physical examination... - Disappearance of a virilizing adrenal tumor following therapy with cyproterone acetateA Lasco
Department of Internal Medicine, University of Messina School of Medicine, Italy
Endocr Relat Cancer 12:939-44. 2005..The patient remains symptom-free. This first report of a curative effect of CPA on a purely virilizing adrenal tumor opens new avenues in the management of such tumors... - Distinctive expression of STAT3 in papillary thyroid carcinomas and a subset of follicular adenomasM Trovato
Department of Pathology, Policlinico Universitario, Messina, Italy
Histol Histopathol 18:393-9. 2003..Because of the communeness of a HGF/c-met/STAT3 pattern between all PTC and a subset of FA, we speculate that a fraction of FA may progress to PTC... - Immunoexpression of the hepatocyte growth factor (HGF), HGF-receptor (c-met) and STAT3 on placental tissues from malformed fetusesM Trovato
Dipartimento di Patologia Umana, Padiglione D, Policlinico Universitario, Messina, Italy
Histol Histopathol 17:691-8. 2002..This immunohistochemical approach could be used in the diagnostic practice of pathologists on chorionic villi biopsy when genetic alterations are absent and ultrasound aspects are doubtful for malformations... - Immunoexpression of the CD30 ligand/CD30 and IL-6/IL-6R signals in thyroid autoimmune diseasesR M Ruggeri
Clinical Experimental Department of Medicine and Pharmacology, University of Messina, Italy
Histol Histopathol 21:249-56. 2006..The two systems could contribute to drive the autoimmune response skewing toward a Th2 phenotype and this appears to be correlated with the lymphoid aggregate grade... - Neural response to transcranial magnetic stimulation in adult hypothyroidism and effect of replacement treatmentVincenzo Rizzo
Department of Physiology and Pharmacology, CUNY School of Medicine, New York, NY 10031, USA
J Neurol Sci 266:38-43. 2008..We investigated the hypothesis that hypothyroidism might affect cortical excitability and modulates inhibitory and excitatory cortical circuits by using Transcranial Magnetic Stimulation... - Residual pituitary function after brain injury-induced hypopituitarism: a prospective 12-month studyGianluca Aimaretti
Division of Endocrinology and Metabolism, Department of Internal Medicine, University of Turin, C.so Dogliotti, 14, 10126 Turin, Italy
J Clin Endocrinol Metab 90:6085-92. 2005..Pituitary function in brain-injured patients may improve over time but, although rarely, may also worsen. Thus, brain-injured patients must undergo neuroendocrine follow-up over time... - Traumatic brain injury and subarachnoid haemorrhage are conditions at high risk for hypopituitarism: screening study at 3 months after the brain injuryGianluca Aimaretti
Division of Endocrinology and Metabolism, Department of Internal Medicine, University of Turin, Turin, Italy
Clin Endocrinol (Oxf) 61:320-6. 2004..The pituitary defect is often multiple and severe GHD is the most frequent defect. Thus neuroendocrine evaluations are always mandatory in patients after brain injuries... - Thyroid hormone autoantibodies in Hashimoto's thyroiditis: often transient but also increasingly frequentSalvatore Benvenga
Thyroid 13:995-6; author reply 996. 2003 - Don't forget the thyroid in the etiology of psychosesSalvatore Benvenga
Am J Med 115:159-60. 2003 - Conformational mutations in neuroserpin and familial dementiasSalvatore Benvenga
Lancet 360:1696. 2002 - Triggering of thyroid hormone autoantibodiesSalvatore Benvenga
J R Soc Med 96:50. 2003 - Cogan's syndrome as an autoimmune diseaseSalvatore Benvenga
Lancet 361:530-1. 2003 - L-carnitine: A nutritional modulator of glucocorticoid receptor functionsSalvatore Alesci
Pediatric and Reproductive Endocrinology Branch, National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland 20892 1583, USA
FASEB J 17:1553-5. 2003.... - Successive thyroid storms treated with L-carnitine and low doses of methimazoleSalvatore Benvenga
Am J Med 115:417-8. 2003 - Environment-induced reactivity against autoallergens: possible role of latexFabrizio Guarneri
J Allergy Clin Immunol 117:957-8. 2006 - Identification of potentially cross-reactive peanut-lupine proteins by computer-assisted search for amino acid sequence homologyFabrizio Guarneri
Istituto di Dermatologia, Policlinico Gaetano Martino, Messina, Italia
Int Arch Allergy Immunol 138:273-7. 2005..However, no lupine allergen has been characterized thus far. Prompted by a recently reported case of peanut-lupine cross-allergy, we wished to identify the possible cross-reactive allergen(s) between the two vegetal species...