Research Topics
| Corrado BarbuiSummaryAffiliation: University of Verona Country: Italy Publications
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Publications
Using the needs of WHO to prioritise Cochrane reviews: The case of antipsychotic drugsMarianna Purgato
Department of Public Health and Community Medicine, Section of Psychiatry and Clinical Psychology, University of Verona, Verona, Italy
Int J Ment Health Syst 5:25. 2011..abstract:..
Persistence with polypharmacy and excessive dosing in patients with schizophrenia treated in four European countriesCorrado Barbui
Department of Medicine and Public Health, Section of Psychiatry and Clinical Psychology, University of Verona, Verona, Italy
Int Clin Psychopharmacol 21:355-62. 2006..Clinicians should consider that dose reduction strategies have been shown to be a feasible intervention in patients with schizophrenia...
Drug treatment modalities in psychiatric inpatient practice: a 20-year comparisonCorrado Barbui
Department of Medicine and Public Health, Section of Psychiatry and Clinical Psychology, University of Verona, Ospedale Policlinico, 37134 Verona, Italy
Eur Arch Psychiatry Clin Neurosci 255:136-42. 2005....
Off-label and non-classical prescriptions of antipsychotic agents in ordinary in-patient practiceC Barbui
Department of Medicine and Public Health, Section of Psychiatry, University of Verona, Ospedale Policlinico, 37134 Verona, Italy
Acta Psychiatr Scand 109:275-8. 2004..To estimate the proportion of off-label prescriptions of antipsychotics (APs) in ordinary in-patient practice...
Amitriptyline for inpatients and SSRIs for outpatients with depression? Systematic review and meta-regression analysisC Barbui
Department of Medicine and Public Health, Section of Psychiatry, University of Verona, Italy
Pharmacopsychiatry 37:93-7. 2004..The aim of this study was to investigate the contribution of study setting on outcome in clinical trials comparing amitriptyline with any other AD...
"Wish bias" in antidepressant drug trials?Corrado Barbui
Section of Psychiatry, Department of Medicine and Public Health, University of Verona, Verona, Italy
J Clin Psychopharmacol 24:126-30. 2004..The evidence that the outcome of fluoxetine trials varied according to whether this drug was used as a new compound or a reference one suggests the presence of bias...
Does the addition of a second antipsychotic drug improve clozapine treatment?Corrado Barbui
Schizophr Bull 35:458-68. 2009..91, 95% CI = 0.75 to 1.11). We conclude that the evidence base supporting a second antipsychotic in addition to clozapine in partially responsive patients with schizophrenia is weak. This weak evidence indicates modest to absent benefit...
Cross-sectional database analysis of antidepressant prescribing in ItalyCorrado Barbui
Istituto di Ricerche Farmacologiche Mario Negri, Milano, Italy
J Clin Psychopharmacol 23:31-4. 2003..The high proportion of occasional antidepressant users suggests that clinical trials should follow all patients, without excluding those who fail to continue the study medication...
Development of a registry for monitoring psychotropic drug prescriptions: aims, methods and implications for ordinary practice and researchCorrado Barbui
Department of Medicine and Public Health, Section of Psychiatry, University of Verona, Italy
Int J Methods Psychiatr Res 14:151-7. 2005....
Decision models in the evaluation of psychotropic drugs : useful tool or useless toy?Corrado Barbui
Dept Medicine and Public Health, Section of Psichiatry and Clinical Psichology, University of Verona, Italy
Eur J Health Econ 7:173-5. 2006..In this commentary, taking the olanzapine vs. risperidone model as an example, arguments are provided to support this statement...
Explanatory and pragmatic trialsCorrado Barbui
Department of Medicine and Public Health, Section of Psychiatry and Clinical Psychology, University of Verona, Piazzale L.A. Scuro, 10 - 37134 Verona, Italy
Epidemiol Psichiatr Soc 16:124-5. 2007
CNS drugs approved by the centralised European procedure: true innovation or dangerous stagnation?Corrado Barbui
Section of Psychiatry and Clinical Psychology, University of Verona, Policlinico GB Rossi, Piazzale Scuro 10, 37134, Verona, Italy
Psychopharmacology (Berl) 190:265-8. 2007
Factors associated with antipsychotic dosing in psychiatric inpatients: a prospective studyCorrado Barbui
Section of Psychiatry and Clinical Psychology, Department of Medicine and Public Health, University of Verona, Verona, Italy
Int Clin Psychopharmacol 22:221-5. 2007..Clinicians should consider that concurrent prescribing of two or more antipsychotic agents increases the probability of administering excessive dosing in the long-term...
Evidence-based psychopharmacology: an agenda for the futureC Barbui
Department of Medicine and Public Health, Section of Psychiatry and Clinical Psychology, University of Verona, Verona, Italy
Evid Based Ment Health 10:4-6. 2007
[Systematic review and clinical decisions in psychiatry]Corrado Barbui
, Sezione di Psichiatria, , Policlinico G.B. Rossi, P.le L.A. Scuro 10, 37134 Verona
Epidemiol Psichiatr Soc 12:154-9. 2003
Validity of the impact factor of journals as a measure of randomized controlled trial qualityCorrado Barbui
Department of Medicine and Public Health, Section of Psychiatry and Clinical Psychology, University of Verona, Policlinico G B Rossi, 37134 Verona, Italy
J Clin Psychiatry 67:37-40. 2006..To assess whether the impact factor, a measure of the frequency with which journal articles are cited in the scientific literature, is a proxy measure of the quality of articles reporting the results of randomized controlled trials...
Psychotropic drug epidemiology: the road travelled, the road aheadCorrado Barbui
Department of Medicine and Public Health, Section of Psychiatry and Clinical Psychiatry, University of Verona, Policlinico GB Rossi, 37134 Verona, Italy
Int Rev Psychiatry 17:143-51. 2005....
What are evidence-based treatment recommendations?C Barbui
Section of Psychiatry and Clinical Psychology, Department of Public Health and Community Medicine, University of Verona, Verona, Italy
Epidemiol Psychiatr Sci 20:29-31. 2011..This article briefly presents how this methodology may be employed to develop treatment recommendations that might constitute a permanent infrastructure between primary research and everyday clinical practice...
Aripiprazole versus haloperidol in combination with clozapine for treatment-resistant schizophrenia in routine clinical care: a randomized, controlled trialCorrado Barbui
World Health Organization Collaborating Centre for Research and Training in Mental Health and Service Organization, Department of Public Health and Community Medicine, Section of Psychiatry and Clinical Psychology, Verona, Italy
J Clin Psychopharmacol 31:266-73. 2011..However, an advantage in the perception of adverse effects with aripiprazole treatment may be meaningful for patients...
Efficacy of antidepressants and benzodiazepines in minor depression: systematic review and meta-analysisCorrado Barbui
Department of Public Health and Community Medicine, Section of Psychiatry and Clinical Psychology, University of Verona, Policlinico GB Rossi, 37134 Verona, Italy
Br J Psychiatry 198:11-6, sup 1. 2011..Depression is a common condition that has been frequently treated with psychotropics...
Health status, resource consumption, and costs of dysthymia. A multi-center two-year longitudinal studyCorrado Barbui
Department of Medicine and Public Health, Section of Psychiatry and Clinical Psychology, University of Verona, Ospedale Policlinico, 37134 Verona, Italy
J Affect Disord 90:181-6. 2006..In this study we estimated the health status, resource consumption and costs of a large cohort of patients with early and late-onset dysthymia...
Effectiveness of paroxetine in the treatment of acute major depression in adults: a systematic re-examination of published and unpublished data from randomized trialsCorrado Barbui
Department of Medicine and Public Health, Section of Psychiatry and Clinical Psychology, World Health Organization Collaborating Centre for Research and Training in Mental Health, University of Verona, Verona, Italy
CMAJ 178:296-305. 2008..We undertook a systematic review of published and unpublished clinical trial data to determine the effectiveness and acceptability of paroxetine...
Comparison of patient and clinician perspectives in the assessment of antipsychotic medication adherenceCorrado Barbui
Section of Psychiatry and Clinical Psychology, Department of Medicine and Public Health, University of Verona, Verona, Italy
Psychopathology 42:311-7. 2009..Factors influencing patient and clinician perspectives in the assessment of medication adherence have never been compared...
Sex differences in the subjective tolerability of antipsychotic drugsCorrado Barbui
Department of Medicine and Public Health, Section of Psychiatry and Clinical Psychology, University of Verona, Italy
J Clin Psychopharmacol 25:521-6. 2005..Studies should no longer consider men and women as a homogeneous group, given that the subjective tolerability of antipsychotic drugs substantially differs between sexes...
Fluoxetine dose and outcome in antidepressant drug trialsCorrado Barbui
Mario Negri Institute for Pharmacological Research, Milan, Italy
Eur J Clin Pharmacol 58:379-86. 2002..The present study compared fluoxetine dose and outcome in trials in which fluoxetine was the experimental drug with trials in which it was the comparator...
[Everyday evidence and practice based medicine: an issue of antidepressants]Corrado Barbui
, Sezione di Psichiatria, , Ospedale Policlinico, 37134 Verona
Epidemiol Psichiatr Soc 11:152-8. 2002
Prescribing second-generation antipsychotics and the evolving standard of care in ItalyC Barbui
Laboratory of Epidemiology and Social Psychiatry, Mario Negri Institute for Pharmacological Research, Milan, Italy
Pharmacopsychiatry 35:239-43. 2002....
Determinants of first- and second-generation antipsychotic drug use in clinically unstable patients with schizophrenia treated in four European countriesCorrado Barbui
Department of Medicine and Public Health, Section of Psychiatry and Clinical Psychology, University of Verona, Italy
Int Clin Psychopharmacol 21:73-9. 2006..Physicians tended to reserve polypharmacy for difficult-to-treat patients (i.e. for managing situations where, despite the lack of an evidence base, there is a pressing need to provide clinical answers)...
Economic evaluation of antidepressive agents: a systematic critique of experimental and observational studiesCorrado Barbui
Department of Medicine and Public Health, Section of Psychiatry, University of Verona, Italy
J Clin Psychopharmacol 23:145-54. 2003..Taken together, available pharmacoeconomic studies indicate that tricyclic drugs and selective serotonin reuptake inhibitors have similar cost effectiveness in the health care systems where these comparisons have been made...
Identification and management of depression in primary care settings. A meta-review of evidenceCorrado Barbui
Department of Medicine and Public Health, Section of Psychiatry and Clinical Psychology, WHO Collaborating Centre for Research and Training in Mental Health and Service Evaluation, University of Verona, Verona, Italy
Epidemiol Psichiatr Soc 15:276-83. 2006....
Rationale and design of an independent randomised controlled trial evaluating the effectiveness of aripiprazole or haloperidol in combination with clozapine for treatment-resistant schizophreniaMichela Nose
Department of Medicine and Public Health, Section of Psychiatry and Clinical Psychology, University of Verona, Italy
Trials 10:31. 2009....
Does randomized evidence support sertraline as first-line antidepressant for adults with acute major depression? A systematic review and meta-analysisAndrea Cipriani
Department of Medicine and Public Health, Section of Psychiatry and Clinical Psychology, University of Verona, Policlinico G B Rossi, Piazzale L A Scuro, 10, 37134 Verona, Italy
J Clin Psychiatry 69:1732-42. 2008..The aim of this study was to carry out a systematic review and meta-analysis to compare sertraline with any other antidepressant in the acute phase treatment of major depression at 8 weeks...
Determinants of antipsychotic polypharmacy in psychiatric inpatients: a prospective studyBruno Biancosino
Section of Psychiatry, Department of Medical Sciences of Communication and Behaviour, University of Ferrara, Ferrara, Italy
Int Clin Psychopharmacol 20:305-9. 2005..Conversely, the theoretical advantage of avoiding a high dose of a single drug is counterbalanced by the documented disadvantage of administering high total doses...
Is the Defined Daily Dose system a reliable tool for standardizing antipsychotic dosages?Michela Nose
Department of Medicine and Public Health, Section of Psychiatry and Clinical Psychology, University of Verona, Italy
Int Clin Psychopharmacol 23:287-90. 2008..In conclusion, this study found that the DDD system is a reliable tool for standardizing antipsychotic doses in drug utilization research...
Antidepressant drug use in Lombardy, Italy: a population-based studyMauro Percudani
Health Care Directorate, Region of Lombardy, Milan, Italy
J Affect Disord 83:169-75. 2004..In the present study, we examined the prevalence and distribution of antidepressant prescribing in Lombardy, a northern Italy region of nine million inhabitants...
Cerebral atrophy and white matter disruption in chronic schizophreniaNicola Andreone
Department of Medicine and Public Health, Section of Psychiatry and Clinical Psychology, University of Verona, Verona, Italy
Eur Arch Psychiatry Clin Neurosci 257:3-11. 2007..It also suggested that physiological aging effects on brain anatomy may be abnormally pronounced in schizophrenia...
Epidemiological impact of antidepressant and antipsychotic drugs on the general populationCorrado Barbui
Department of Medicine and Public Health, Section of Psychiatry and Clinical Psychology, University of Verona, Italy
Curr Opin Psychiatry 19:405-10. 2006..SUMMARY: The assessment of, and attention to, the development of specific adverse reactions in individuals exposed to second-generation psychotropic drugs may improve treatment outcomes...
Past use of selective serotonin reuptake inhibitors and the risk of cerebrovascular events in the elderlyCorrado Barbui
Department of Medicine and Public Health, Section of Psychiatry and Clinical Psychology, University of Verona, Italy
Int Clin Psychopharmacol 20:169-71. 2005..31, 95% CI 0.87-1.97). Although the risk of cerebrovascular accidents is a rare but serious event that should carefully be monitored during antidepressant therapy, this study indicated an absence of difference between TCAs and SSRIs...
Prevalence, incidence and persistence of antipsychotic drug prescribing in the Italian general population: retrospective database analysis, 1999-2002Mersia Mirandola
Servizio Farmaceutico ULSS 20, Verona, Italy
Pharmacoepidemiol Drug Saf 15:412-20. 2006....
Sertraline versus other antidepressive agents for depressionAndrea Cipriani
Department of Medicine and Public Health, Section of Psychiatry and Clinical Psychology, University of Verona, Policlinico G B Rossi, Piazzale L A Scuro, 10, Verona, Italy, 37134
Cochrane Database Syst Rev 4:CD006117. 2010..However, the included studies did not report on all the outcomes that were pre-specified in the protocol of this review. Outcomes of clear relevance to patients and clinicians were not reported in any of the included studies...
Impact of regulatory changes on first- and second-generation antipsychotic drug consumption and expenditure in ItalyMargherita Andretta
Servizio Farmaceutico, ULSS 20, Verona, Italy
Soc Psychiatry Psychiatr Epidemiol 40:72-7. 2005....
Understanding antipsychotic non-classical prescriptions: a quantitative and qualitative approachAntonio Veronese
Department of Medicine and Public Health, Section of Psychiatry and Clinical Psychology, University of Verona, Piazzale L A Scuro 10, 37134 Verona, Italy
Epidemiol Psichiatr Soc 17:236-41. 2008..The present study was carried out to develop concepts which help understand this phenomenon in a natural setting, giving emphasis to views of clinicians according to quali - quantitative research methodologies...
Benzodiazepine use in the real world of psychiatric practice: low-dose, long-term drug taking and low rates of treatment discontinuationAntonio Veronese
Department of Medicine and Public Health, Section of Psychiatry and Clinical Psychology, University of Verona, Ospedale Policlinico, 37134, Verona, Italy
Eur J Clin Pharmacol 63:867-73. 2007....
Adverse effects of antipsychotic drugs: survey of doctors' versus patients' perspectiveMichela Nose
Department of Public Health and Community Medicine, Section of Psychiatry and Clinical Psychology, University of Verona, Policlinico GB Rossi, 37134 Verona, Italy
Soc Psychiatry Psychiatr Epidemiol 47:157-64. 2012..The aim of this survey is to compare doctors' versus patients' perspective on the presence and level of distress due to antipsychotic adverse effects in a sample of patients under the care of the South-Verona mental health services...
Antidepressant drug prescription and risk of abnormal bleeding: a case-control studyCorrado Barbui
Department of Medicine and Public Health, Section of Psychiatry and Clinical Psychology, WHO Collaborating Centre for Research and Training in Mental Health, University of Verona, Italy
J Clin Psychopharmacol 29:33-8. 2009..74; 95% CI, 1.04-2.93). In a population with a low baseline risk of bleeding, we detected a significant increase in the risk of gastrointestinal bleeding only...
Are we going to increase the use of antidepressants up to that of benzodiazepines?Arcangelo Ciuna
Servizio Farmaceutico ULSS 20, Verona, Italy
Eur J Clin Pharmacol 60:629-34. 2004..CONCLUSIONS: In Italy, the consumption of benzodiazepines was not affected by the increased prescribing of selective serotonin-reuptake inhibitors and newer antidepressants...
Selective serotonin reuptake inhibitors and risk of suicide: a systematic review of observational studiesCorrado Barbui
World Health Organization Collaborating Centre for Research and Training in Mental Health, Department of Medicine and Public Health, Section of Psychiatry and Clinical Psychology, University of Verona, Verona, Italy
CMAJ 180:291-7. 2009..We explored the association between exposure to SSRIs and risk of suicide completion or attempt...
Relationship between quality of reports of antidepressant randomized controlled trials and treatment estimates: systematic review, meta-analysis, and meta-regression analysisAndrea Cipriani
Department of Medicine and Public Health, Section of Psychiatry and Clinical Psychology, University of Verona, Verona, Italy
J Clin Psychopharmacol 27:352-6. 2007..However, current quality measures are not related with treatment estimates in antidepressant trials and may not be useful weighting tools when meta-analyses of data extracted from antidepressant RCTs are carried out...
Second-generation antipsychotics and risk of cerebrovascular accidents in the elderlyMauro Percudani
Health Care Directorate, Region of Lombardy, Milan, Italy
J Clin Psychopharmacol 25:468-70. 2005..12-1.93). These data provide preliminary epidemiological evidence that exposure to SGAs, in comparison with exposure to first-generation antipsychotics, significantly increased the risk of cerebrovascular accidents in the elderly...
Assessment of cerebral blood volume in schizophrenia: A magnetic resonance imaging studyPaolo Brambilla
Department of Pathology and Experimental and Clinical Medicine, Section of Psychiatry, University of Udine, Udine, Italy
J Psychiatr Res 41:502-10. 2007..Thus, altered intracranial hemodynamics may accompany brain atrophy and cognitive deficits, being a crucial factor in the pathophysiology of schizophrenia...
Are all antidepressants really the same? The case of fluoxetine: a systematic reviewAndrea Cipriani
Department of Medicine and Public Health, Section of Psychiatry and Clinical Psychology, University of Verona, Verona, Italy
J Clin Psychiatry 67:850-64. 2006..To systematically review the efficacy and tolerability of fluoxetine, the most widely studied of newer antidepressants, in comparison with all other antidepressants in the acute treatment of depression in patients aged more than 18 years...
Violence in psychiatric units: a 7-year Italian study of persistently assaultive patientsLuigi Grassi
Section of Psychiatry, Department of Medical Sciences of Communication and Behaviour, University of Ferrara, Ferrara, Italy
Soc Psychiatry Psychiatr Epidemiol 41:698-703. 2006..The aim of this paper is to describe the characteristics of repeated episodes of violence among patients admitted to an Italian psychiatric ward...
Seven criteria for improving effectiveness trials in psychiatryMichele Tansella
Department of Medicine and Public Health, Section of Psychiatry and Clinical Psychology, University of Verona, Italy
Psychol Med 36:711-20. 2006..There are no published criteria for improving the quality of effectiveness of randomized controlled trials (RCTs) in psychiatry...
Antidepressant drug prescribing among elderly subjects: a population-based studyMauro Percudani
Health Care Directorate, Region of Lombardy, Milan, Italy
Int J Geriatr Psychiatry 20:113-8. 2005..In the present study we examined the prevalence and distribution of antidepressant prescribing in Lombardy, a northern Italy region with more than one and a half million elderly inhabitants...
Comparative efficacy and acceptability of antimanic drugs in acute mania: a multiple-treatments meta-analysisAndrea Cipriani
Department of Public Health and Community Medicine, Section of Psychiatry and Clinical Psychology, University of Verona, Italy
Lancet 378:1306-15. 2011..We did a multiple-treatments meta-analysis, which accounted for both direct and indirect comparisons, to assess the effects of all antimanic drugs...
Antipsychotic drug prescribing in the elderly is cause for concernMauro Percudani
Health Care Directorate, Region of Lombardy, Milan, Italy
Int Clin Psychopharmacol 19:347-50. 2004....
Relationship between self-reported and observer-reported ratings for psychopathology in psychiatric inpatientsBruno Biancosino
Section of Psychiatry, Department of Medical Sciences of Communication and Behaviour, University of Ferrara, Ferrara, Italy
Psychopathology 40:418-23. 2007..Psychopathology can be measured adopting the perspective of clinicians or the perspective of patients themselves. In the present study, we investigated the degree of coherence between these two viewpoints...
Health status, resource consumption, and costs of dysthymic patients in Italian primary careCorrado Barbui
Laboratory of Epidemiology and Social Psychiatry, Mario Negri Institute for Pharmacological Research, Milan, Italy
Epidemiol Psichiatr Soc 13:120-5. 2004..All dysthymic patients diagnosed by GPs might be considered together from a health policy perspective...
Routine outcome monitoring in clinical practice: service and non-service costs of psychiatric patients attending a Community Mental Health Centre in ItalyMauro Percudani
Department of Mental Health, Hospital of Legnano, Via Candiani 2, 20025 Legnano, Milan, Italy
Eur Psychiatry 19:469-77. 2004..This study estimated service and non-service costs in a random sample of patients attending a community psychiatric mental health centre in Italy...
Head-to-head comparison of the costs of atypical antipsychotics: a systematic reviewCorrado Barbui
Department of Medicine and Public Health, Section of Psychiatry and Clinical Psychology, University of Verona, Verona, Italy
CNS Drugs 19:935-50. 2005..As healthcare providers in different settings are ultimately the ones who pay for new innovations, it seems appropriate that they commission research into the cost effectiveness of SGAs...
Generating psychotropic drug exposure data from computer-based medical recordsChiara Bonetto
Department of Medicine and Public Health, Section of Psychiatry and Clinical Psychology, University of Verona, Verona, Italy
Comput Methods Programs Biomed 83:120-4. 2006....
[Systemic review of clinical interventions for reducing treatment non-adherence in psychosis]Michela Nose
Dipartimento di Medicina e Sanita Pubblica, Sezione di Psichiatria, Universita di Verona, Policlinico G B Rossi, P le L A Scuro 10, 37134 Verona
Epidemiol Psichiatr Soc 12:272-86. 2003..This systematic review was carried out to investigate the efficacy of clinical interventions that community psychiatric services can implement to reduce non-adherence in patients with psychosis...
Cost and outcome implications of using typical and atypical antipsychotics in ordinary practice in ItalyMauro Percudani
Department of Psychiatry, Hospital of Legnano, Milan, Italy
J Clin Psychiatry 64:1293-9. 2003..CONCLUSIONS: The introduction of atypical agents had a small impact in terms of total health care costs and outcome, and more important than the agent prescribed was the severity of illness...
Epidemiology of first- and second-generation antipsychotic agents in Lombardy, ItalyM Percudani
Health Care Directorate, Region of Lombardy, Milan, Italy
Pharmacopsychiatry 38:128-31. 2005..This study investigated the age and gender distribution of antipsychotic prescribing in Lombardy, a region of nine million inhabitants in northern Italy...
Patterns of benzodiazepine use in a Canadian population sampleEleonora Esposito
Department of Medicine and Public Health, Section of Psychiatry and Clinical Psychology, University of Verona, Verona, Italy
Epidemiol Psichiatr Soc 18:248-54. 2009....
Metareview on short-term effectiveness and safety of antidepressants for depression: an evidence-based approach to inform clinical practiceAndrea Cipriani
Department of Medicine and Public Health, University of Verona, Italy
Can J Psychiatry 52:553-62. 2007....
What is an individual patient data meta-analysis?Andrea Cipriani
Epidemiol Psichiatr Soc 16:203-4. 2007
Allocation concealment and blinding in clinical trialsAndrea Cipriani
Department of Medicine and Public Health, Section of Psychiatry and Clinical Psychology, University of Verona, Verona, Italy
Epidemiol Psichiatr Soc 17:115-6. 2008
What is an intention to treat analysis?Andrea Cipriani
Department of Medicine and Public Health, Section of Psychiatry and Clinical Psychology, University of Verona, Verona, Italy
Epidemiol Psichiatr Soc 17:26-7. 2008
What is a risk ratio?Andrea Cipriani
Department of Medicine and Public Health, Section of Psychiatry and Clinical Psychology, University of Verona, Piazzale L.A. Scuro, 10, 37134 Verona, Italy
Epidemiol Psichiatr Soc 16:20-1. 2007
Stressful life events and social health factors in women using anxiolytics and antidepressants: an Italian observational study in community pharmaciesPaola D'Incau
Department of Community Medicine and Public Health, Section of Clinical Pharmacology Unit, University of Verona, Verona, Italy
Gend Med 8:80-92. 2011..Women are more likely than men to have experienced poverty, gender discrimination, and physical and sexual abuse...
Monitoring community psychiatric services in Italy: differences between patients who leave care and those who stay in treatmentMauro Percudani
Department of Psychiatry, Hospital of Legnano, and Laboratory of Epidemiology and Social Psychiatry, Mario Negri' Institute for Pharmacological Research, Milan, Italy
Br J Psychiatry 180:254-9. 2002..Those who stay in treatment are more likely to suffer from psychosis, suggesting a commitment of Italian out-patient facilities to tackling the needs of patients with more severe disorders...
What is a clinical trial protocol?Andrea Cipriani
Department of Medicine and Public Health, Section of Psychiatry and Clinical Psychology, University of Verona, Italy
Epidemiol Psichiatr Soc 19:116-7. 2010..Trial protocols must meet a standard that adheres to the principles of Good Clinical Practice, and are used to obtain ethics approval by local Ethics Committees or Institutional Review Boards...
What is a forest plot?Andrea Cipriani
Department of Medicine and Public Health, Section of Psychiatry and Clinical Psychology, University of Verona, Piazzale L.A. Scuro, 10-37134 Verona, Italy
Epidemiol Psichiatr Soc 15:258-9. 2006
Superiority, equivalence or non-inferiority?Andrea Cipriani
Department of Medicine and Public Health, Section of Psychiatry and Clinical Psychology, University of Verona, Verona, Italy
Epidemiol Psichiatr Soc 18:311-3. 2009..Three kinds of RCTs may be designed: Superiority trials, Equivalence studies, Non-inferiority studies...
Antipsychotic drugs and cerebrovascular events in elderly patients with dementia: a systematic reviewSara Mazzucco
Department of Neurological Sciences and Vision, Section of Clinical Neurology, University of Verona, Piazzale L A Scuro, 10, 37134 Verona, Italy
Mini Rev Med Chem 8:776-83. 2008..Assessing both randomised and non-randomised evidence, this systematic review found conflicting findings, particularly for risperidone. More research is needed to better inform clinical practice...
Mortality and cause of death among psychiatric patients: a 20-year case-register study in an area with a community-based system of careL Grigoletti
Department of Medicine and Public Health, Section of Psychiatry and Clinical Psychology, University of Verona, Italy
Psychol Med 39:1875-84. 2009....
Determinants of subjective quality of life in patients attending community-based mental health services. The South-Verona Outcome Project 5M Ruggeri
Department of Medicine and Public Health, Section of Psychiatry, University of Verona, Italia
Acta Psychiatr Scand 105:131-40. 2002....
Avoidable mortality of psychiatric patients in an area with a community-based system of mental health careF Amaddeo
Department of Medicine and Public Health, Section of Psychiatry and Clinical Psychology, University of Verona, Verona, Italy
Acta Psychiatr Scand 115:320-5. 2007....
Clinical databases of patients receiving antidepressants. The missing link between research and practice?Corrado Barbui
Istituto di Ricerche Farmacologiche Mario Negri, Via Eritrea 62, 20157, Milano, Italy
J Affect Disord 70:191-6. 2002..Unfortunately, the epidemiology of these compounds has shown significant gaps between recommendations derived from randomised controlled trials and current clinical practice...
Antidepressant drug use in Italy since the introduction of SSRIs: national trends, regional differences and impact on suicide ratesC Barbui
Istituto di Ricerche Farmacologiche Mario Negri, Milano, Italy
Soc Psychiatry Psychiatr Epidemiol 34:152-6. 1999..9 to 3.2 per 100,000. These data suggest that SSRIs gave a new impetus to antidepressant sales. However, possible public health benefits related to the shift from old to new antidepressants have yet to be demonstrated...
Clozapine-treated subjects with treatment-resistant schizophrenia: a systematic review of experimental and observational studiesP Brambilla
Mario Negri Institute for Pharmacological Research, Milano, Italy
Int Clin Psychopharmacol 17:189-95. 2002..A new generation of observational studies should be developed to provide evidence on patient outcome in typical settings and under real-world circumstances, and on variables which may affect outcome...
Drug epidemiology in Italy: methods and ethical issues. The example of psychiatryC Barbui
Laboratory of Epidemiology and Social Psychiatry, WHO Collaborating Centre for Research and Training in Mental Health, Mario Negri Institute for Pharmacological Research, Milano, Italy
Pharmacoepidemiol Drug Saf 10:647-52. 2001..These notes aim at analysing current methods, ethical issues and major legislation changes related to drug epidemiology in Italy...
The Qualyop Project. 1: Monitoring the dismantlement of Italian public psychiatric hospitals. Characteristics of patients scheduled for dischargeB D'Avanzo
Laboratorio di Epidemiologia e Psichiatria Sociale, Istituto di Ricerche Farmacologiche Mario Negri, Milan, Italy
Int J Soc Psychiatry 45:79-92. 1999....
Clinical trials of new antipsychotics: a critical appraisalC Barbui
Laboratory of Epidemiology and Social Psychiatry, WHO Collaborating Centre for Research and Training in Mental Health, Mario Negri Institute for Pharmacological Research, Milan, Italy
Int Clin Psychopharmacol 14:133-7. 1999..The final goal is the implementation of a new generation of trials with the aim of demonstrating superiority of effect of the new antipsychotic over the reference one...
Psychotropic drug use in Italy, 1984-99: the impact of a change in reimbursement statusC Barbui
Laboratory of Epidemiology and Social Psychiatry, WHO Collaborating Centre for Research and Training in Mental Health, Mario Negri Institute for Pharmacological Research, Milano, Italy
Int Clin Psychopharmacol 16:227-33. 2001..This analysis highlights specific areas of concern which should become the object of public health programs...
Cortical white-matter microstructure in schizophrenia. Diffusion imaging studyN Andreone
Department of Medicine and Public Health, University of Verona, Italy
Br J Psychiatry 191:113-9. 2007..Several, although not all, of the previous small diffusion-weighted imaging (DWI) studies have shown cortical white-matter disruption in schizophrenia...
Side-effect profile of fluoxetine in comparison with other SSRIs, tricyclic and newer antidepressants: a meta-analysis of clinical trial dataP Brambilla
Department of Pathology and Experimental Medicine, Section of Psychiatry, University of Udine, Udine, Italy
Pharmacopsychiatry 38:69-77. 2005....
Efficacy and tolerability of milnacipran in the treatment of major depression in comparison with other antidepressants : a systematic review and meta-analysisAtsuo Nakagawa
Department of Neuropsychiatry, Keio University, School of Medicine, Tokyo, Japan
CNS Drugs 22:587-602. 2008..We undertook a systematic review and meta-analysis of randomized controlled trials that compared the efficacy and tolerability of milnacipran with other antidepressants...
[Antidepressant and antipsychotic drug prescribing in Lombardy]Mauro Percudani
Direzione Generale Sanita, Regione Lombardia, Milano
Epidemiol Psichiatr Soc 15:59-70. 2006..In the present study we examined the prevalence and distribution of antidepressant and antipsychotic prescribing in Lombardy, a northern Italy region of nine million inhabitants...
Mild depression in general practice: is the automatism of antidepressant prescribing an evidence-based approach?Corrado Barbui
Acta Psychiatr Scand 113:449-51. 2006
International dosage differences in fluoxetine clinical trialsScott Patten
Department of Community Health Sciences, University of Calgary, Alberta
Can J Psychiatry 50:31-8. 2005..CONCLUSIONS: International differences in prescriber behaviour may influence, and in turn be influenced by, the conduct of clinical trials. It is difficult to reconcile such differences with the principles of evidence-based medicine...
Antidepressant drugs: prevalence, incidence and indication of use in general practice of Southern Italy during the years 2003-2004Gianluca Trifiro
Department of Clinical and Experimental Medicine and Pharmacology, Pharmacology Unit, University of Messina, Messina, Italy
Pharmacoepidemiol Drug Saf 16:552-9. 2007..To estimate 1-year prevalence, 1-year incidence and indication of use of antidepressant (AD) drug treatment in general practice of Southern Italy during the years 2003-2004...
Imputing missing standard deviations in meta-analyses can provide accurate resultsToshi A Furukawa
Department of Psychiatry and Cognitive Behavioral Medicine, Nagoya City University Graduate School of Medical Sciences, Mizuho cho, Mizuho ku, Nagoya 467 8601 Japan
J Clin Epidemiol 59:7-10. 2006..Some meta-analysts substitute them by those reported in other studies, either from another meta-analysis or from other studies in the same meta-analysis. But the validity of such practices has never been empirically examined...
Antidepressant drug consumption and public health indicators in Italy, 1955 to 2000Giuseppe Guaiana
Department of Psychiatry, University of Hull, UK
J Clin Psychiatry 66:750-5. 2005..Furthermore, in Italy, newer antidepressants had no impact on the total number of admissions for depression or on the proportion of all admissions that were first admissions...
The prevalence of antidepressant and antipsychotic drug prescribing in Lombardy, ItalyMauro Percudani
J Clin Psychopharmacol 25:92-4. 2005
Antidepressants and the risk of suicidal behaviorsCorrado Barbui
JAMA 292:2833; author reply 2833. 2004
Trends in the use of the Italian Mental Health Act, 1979--1997Giuseppe Guaiana
The University of Hull, Hertford Building, Cottingham Road, Hull HU6 7RX, UK
Eur Psychiatry 19:444-5. 2004..The proportion of all admissions that were compulsory decreased from 17.1% to 11%. This study shows that a shift to community care was not associated with an increase in compulsory admissions in Italy...
