Research Topics
| Valentina AmbrosiniSummaryAffiliation: University of Bologna Country: Italy Publications
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Detail Information
Publications
??Ga-labelled peptides for diagnosis of gastroenteropancreatic NETValentina Ambrosini
Nuclear Medicine, S Orsola Malpighi University Hospital, Bologna, Italy
Eur J Nucl Med Mol Imaging 39:S52-60. 2012....
F-18 FDG PET/CT detects muscle involvement in Erdheim-Chester diseaseValentina Ambrosini
Department of Nuclear Medicine, S Orsola Malpighi University Hospital, Bologna, Italy
Clin Nucl Med 37:196-7. 2012..Chronic steroid and hormone replacement therapy was administered, and the patient was asymptomatic. F-18 FDG PET/CT was useful for disease restaging at cardiac and soft tissues level...
68Ga-DOTA-NOC PET/CT detects somatostatin receptors expression in von hippel-lindau cerebellar diseaseValentina Ambrosini
Departments of Nuclear Medicine, Azienda Ospedaliero Universitaria di Bologna, S Orsola Malpighi University Hospital, Bologna, Italy
Clin Nucl Med 36:64-5. 2011....
68Ga-DOTANOC PET/CT allows somatostatin receptor imaging in idiopathic pulmonary fibrosis: preliminary resultsValentina Ambrosini
Nuclear Medicine, Azienda Ospedaliero Universitaria di Bologna, S Orsola Malpighi Hospital, Bologna, Italy
J Nucl Med 51:1950-5. 2010..The aim of this study was to evaluate (68)Ga-DOTANOC PET/CT in patients with IPF and NSIP...
68Ga-DOTANOC PET/CT clinical impact in patients with neuroendocrine tumorsValentina Ambrosini
Department of Nuclear Medicine, Azienda Ospedaliero Universitaria di Bologna, S Orsola Malpighi University Hospital, Bologna, Italy
J Nucl Med 51:669-73. 2010..The aim of this study was to assess the impact of (68)Ga-DOTANOC PET/CT on the clinical management of NET patients...
Comparison between 68Ga-DOTA-NOC and 18F-DOPA PET for the detection of gastro-entero-pancreatic and lung neuro-endocrine tumoursValentina Ambrosini
Unità Operativa di Medicina Nucleare, Azienda Ospedaliero Universitaria di Bologna, Policlinico S Orsola Malpighi, Padiglione 30, Via Massarenti 9, 40138, Bologna, Italy
Eur J Nucl Med Mol Imaging 35:1431-8. 2008..At present, there are no comparative studies investigating their role in NET...
(68)Ga-DOTA-NOC PET/CT in comparison with CT for the detection of bone metastasis in patients with neuroendocrine tumoursValentina Ambrosini
Department of Nuclear Medicine, S Orsola Malpighi University Hospital, Bologna, Italy
Eur J Nucl Med Mol Imaging 37:722-7. 2010..To retrospectively evaluate the sensitivity, specificity and accuracy of (68)Ga-DOTA-NOC PET/CT and CT alone for the evaluation of bone metastasis in patients with neuroendocrine tumour (NET)...
68Ga-DOTA-NOC: a new PET tracer for evaluating patients with bronchial carcinoidValentina Ambrosini
Department of Nuclear Medicine, Policlinico S Orsola Malpighi Hospital, Bologna, Italy
Nucl Med Commun 30:281-6. 2009..However, their role in BC has never been evaluated. Our aim is to evaluate the role of 68Ga-DOTA-NOC (68Ga-labelled [1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetic acid]-1-Nal3-octreotide) PET for the assessment of BC patients...
Evaluation of unusual neuroendocrine tumours by means of 68Ga-DOTA-NOC PETStefano Fanti
Unità Operativa di Medicina Nucleare, Policlinico S Orsola Malpighi, Bologna, Italy
Biomed Pharmacother 62:667-71. 2008..On the other hand, care has to be paid when studying lesions localized at sites of physiological concentration of the tracer, and in presence of inflammation...
11C-choline vs. 18F-FDG PET/CT in assessing bone involvement in patients with multiple myelomaCristina Nanni
Nuclear Medicine, PET Unit, Policlinico S Orsola Malpighi, Bologna University, Italy
World J Surg Oncol 5:68. 2007..Whole body skeletal survey (WBSS), Magnetic resonance (MR) and 18F-FDG PET/CT are imaging techniques routinely used for the evaluation of bone involvement in MM patients...
Role of 18F-dopa PET/CT imaging in the management of patients with 111In-pentetreotide negative GEP tumoursValentina Ambrosini
Unità Operativa di Medicina Nucleare, Policlinico S Orsola Malpighi, Bologna, Italy
Nucl Med Commun 28:473-7. 2007....
Late FDG PET normalization after radioimmunotherapy in a patient with non-Hodgkin lymphomaAnna Margherita Maffione
Unità Operativa di Medicina Nucleare, Policlinico S Orsola Malpighi, Bologna, Italy
Clin Nucl Med 34:777-8. 2009..This case indicates that after completion of radioimmunotherapy it may be recommended to wait several weeks before performing a PET scan and, in case of minimal findings, to consider a short-term re-evaluation...
Assessment of a chemically induced model of lung squamous cell carcinoma in mice by 18F-FDG small-animal PETValentina Ambrosini
Nuclear Medicine Department, Policlinico S Orsola Malpighi, Bologna University, Italy
Nucl Med Commun 28:647-52. 2007..There are various murine models for human lung adenocarcinoma, but those for squamous cell lung carcinoma, the most common form of human cancer, are lacking...
68Ga-citrate PET/CT for evaluating patients with infections of the bone: preliminary resultsCristina Nanni
Medicina Nucleare, Azienda Ospedaliero Universitaria di Bologna, Policlinico S Orsola Malpighi, Bologna, Italy
J Nucl Med 51:1932-6. 2010..The aim of this work was to preliminarily evaluate the sensitivity, specificity, positive predictive value, negative predictive value, and overall accuracy of (68)Ga-citrate PET/CT in a population of patients with suspected bone infections...
Is there a role for ¹¹C-choline PET/CT in the early detection of metastatic disease in surgically treated prostate cancer patients with a mild PSA increase <1.5 ng/ml?Paolo Castellucci
Service of Nuclear Medicine, Department of Haematology Oncology and Laboratory Medicine, Azienda Ospedaliero Universitaria di Bologna, Policlinico Sant Orsola Malpighi, University of Bologna, Bologna, Italy
Eur J Nucl Med Mol Imaging 38:55-63. 2011..5 ng/ml (early biochemical relapse) during follow-up (FU)...
Incidence of increased 68Ga-DOTANOC uptake in the pancreatic head in a large series of extrapancreatic NET patients studied with sequential PET/CTPaolo Castellucci
Nuclear Medicine Unit, Hematology Oncology and Laboratory Medicine Department, Azienda Ospedaliero Universitaria di Bologna Policlinico S Orsola Malpighi, University of Bologna, Bologna, Italy
J Nucl Med 52:886-90. 2011....
Role of [18F]fluorodeoxyglucose positron emission tomography scan in the follow-up of lymphomaPier Luigi Zinzani
Institute of Hematology and Oncology L and A Seragnoli, University of Bologna, Bologna, Italy
J Clin Oncol 27:1781-7. 2009..However, there are no prospective studies investigating the value of serial FDG-PET over time in patients in complete remission...
Focal lung uptake of 18F-fluorodeoxyglucose (18F-FDG) without computed tomography findingsMohsen Farsad
UO Medicina Nucleare, , Policlinico S. Orsola-Malpighi, Via Massarenti 9, 40138 Bologna, Italy
Nucl Med Commun 26:827-30. 2005..The only common feature to all was the paravenous injection of the radiotracer. CONCLUSION: The lesions detected by PET may be related to distal lung microembolism originating from the site of paravenous injection...
(18)F-FDG PET in Pediatric Lymphomas: A Comparison with Conventional ImagingEgesta Lopci
Department of Nuclear Medicine, Policlinico S Orsola Malpighi, Bologna, Italy
Cancer Biother Radiopharm 23:681-90. 2008..4% specificity for CI. This comparative study shows FDG PET to be more accurate than CI in evaluating children with lymphoma. Our data also confirms that (18)F-FDG PET may show false-positive findings...
Additional value of hybrid PET/CT fusion imaging vs. conventional CT scan alone in the staging and management of patients with malignant pleural mesotheliomaValentina Ambrosini
Nuclear Medicine Service - PET Unit, Policlinico S. Orsola-Malpighi, Bologna University, Bologna, Italy
Nucl Med Rev Cent East Eur 8:111-5. 2005..3% of cases). CONCLUSIONS: Our data show that (18)F-FDG PET/CT fusion imaging can play a relevant role in the staging and treatment planning of MPM patients...
18F-FDG PET/CT in myeloma with presumed solitary plasmocytoma of boneCristina Nanni
Department of Nuclear Medicine, Policlinico S Orsola Malpighi, Bologna, Italy
In Vivo 22:513-7. 2008..To evaluate the value of 18F-fluorodeoxy-glucose (FDG) positron emission tomography with computed tomography (PET/CT) in myeloma in patients presenting with a solitary plasmacytoma of bone (SPB)...
Diagnostic role of 18F-FDG PET in gastric MALT lymphomaValentina Ambrosini
Department of Nuclear Medicine - PET Unit, Policlinico S. Orsola-Malpighi Hospital, Bologna, Italy
Nucl Med Rev Cent East Eur 9:37-40. 2006..CONCLUSION: Our data demonstrate the significant accuracy of 18F-FDG-PET in detecting active disease in gastric lymphoma of both MALT and non-MALT NHL type. A higher SUV value appears to be related to a more aggressive disease...
Small animal PET in oncology: the road from bench to bedsideValentina Ambrosini
Department of Nuclear Medicine, Policlinico S Orsola Malpighi, Azienda Ospedaliero Universitaria di Bologna, Bologna, Italy
Cancer Biother Radiopharm 24:277-85. 2009..This review focuses on the applications of SA-PET for the visualization of the pathophysiologic pathways of tumor cells...
Early relapse in a patient with Hodgkin's disease and negative interim FDG-PETStefano Fanti
Unità Operativa di Medicina Nucleare, Padiglione 30, Azienda Ospedaliero Universitaria di Bologna, Policlinico S Orsola Malpighi, Via Massarenti 9, 40138 Bologna, Italy
Ann Nucl Med 22:429-32. 2008..This case testifies the possibility of early relapse of lymphoma even in the case of negative interim PET; it also supports the usefulness of end-treatment PET scan in lymphoma patients...
FDG small animal PET permits early detection of malignant cells in a xenograft murine modelCristina Nanni
Nuclear Medicine, Azienda Ospedaliera di Bologna Policlinico S Orsola Malpighi, Bologna, Italy
Eur J Nucl Med Mol Imaging 34:755-62. 2007..A second goal was to analyse the metabolic behaviour of this xenograft tumour over time...
Small animal PET for the evaluation of an animal model of genital infectionCristina Nanni
Department of Nuclear Medicine, Azienda Ospedaliero Universitaria di Bologna, Policlinico S Orsola Malpighi, Bologna, Italy
Clin Physiol Funct Imaging 29:187-92. 2009..Since the 1970s, Gallium scintigraphy is a well established test that has been used for the evaluation of inflammation and infection in human patients...
Standardized uptake values of (68)Ga-DOTANOC PET: a promising prognostic tool in neuroendocrine tumorsDavide Campana
Department of Clinical Medicine, Policlinico S Orsola Malpighi Hospital, University of Bologna, Bologna, Italy
J Nucl Med 51:353-9. 2010..Therefore, we prospectively investigated whether (68)Ga-[1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetic acid]-1-NaI3-octreotide ((68)Ga-DOTANOC) PET SUVmax could be used as an accurate noninvasive marker for disease prognosis...
Positron-emission tomography in gynaecologic malignanciesAnna Margherita Maffione
Department of Nuclear Medicine, Policlinico S Orsola Malpighi, Bologna, Italy
Arch Gynecol Obstet 280:521-8. 2009..However, this under utilisation is being actively re-addressed with a large number of reviews and studies, particularly in the last few years...
PET/CT with 68Gallium-DOTA-peptides in NET: an overviewValentina Ambrosini
Department of Nuclear Medicine, Sant Orsola Malpighi University Hospital, Bologna, Italy
Eur J Radiol 80:e116-9. 2011....
PET/CT imaging in different types of lung cancer: An overviewValentina Ambrosini
Department of Nuclear Medicine, Sant Orsola Malpighi Hospital, Bologna, Italy
Eur J Radiol 81:988-1001. 2012....
Alveolar Rhabdomyosarcoma With Neuroendocrine Differentiation Detected by Ga-68 DOTA-NOC PET/CT: A Case ReportLucia Zanoni
From the PET Center, Department of Nuclear Medicine, University Hospital S Orsola Malpighi, Bologna, Italy and Radiopharmacy, Department of Nuclear Medicine, University Hospital S Orsola Malpighi, Bologna, Italy
Clin Nucl Med 36:915-8. 2011..Ga-68 DOTA-NOC PET/CT demonstrated multiple lesions in her axilla, thoracic spine, and retroperitoneum. Biopsy of a palpable nodule at her left forearm revealed alveolar rhabdomyosarcoma with neuroendocrine differentiation...
Radiopeptide imaging and therapy in EuropeValentina Ambrosini
Nuclear Medicine, S Orsola Malpighi University Hospital, Bologna, Italy
J Nucl Med 52:42S-55S. 2011..Finally, another peptide family, the arginine-glycine-aspartate-based radiotracers, has made it to the clinic labeled with a variety of radioisotopes for monitoring the integrins ?(v)?(3) overexpressed during tumor angiogenesis...
Antitumor activity of sustained N-myc reduction in rhabdomyosarcomas and transcriptional block by antigene therapyRoberto Tonelli
Department of Pediatric Hematology, University of Bologna, Bologna, Italy
Clin Cancer Res 18:796-807. 2012..Our aim was to determine the prevalence of N-Myc protein expression and the potential therapeutic effects of reducing expression in rhabdomyosarcomas, including use of an antigene strategy that inhibits transcription...
Role of 18F-FDG-PET and PET/CT imaging in thyroid cancerCristina Nanni
Department of Radiology, Istituto Oncologico Veneto (IOV, Padova, Italy
Biomed Pharmacother 60:409-13. 2006....
18F-FDG PET in mucosa-associated lymphoid tissue (MALT) lymphomaLapo Alinari
Institute of Hematology and Oncology Seragnoli, University of Bologna, Italy
Leuk Lymphoma 47:2096-101. 2006..Sensitivity of 18F FDG-PET for extra-nodal MALT was 81%. The data show that 18FDG-PET is a useful diagnostic tool in order to stage, restage or monitor disease in patients with extra-nodal MALT lymphoma...
68Ga-DOTA-peptides versus 18F-DOPA PET for the assessment of NET patientsValentina Ambrosini
Nucl Med Commun 29:415-7. 2008
Discordant response to chemotherapy: an unusual pattern of fluoro-deoxy-D-glucose uptake in heavily pre-treated lymphoma patientsLapo Alinari
, Italy
Leuk Lymphoma 47:1048-52. 2006....
Retro-orbital injection is an effective route for radiopharmaceutical administration in mice during small-animal PET studiesCristina Nanni
Nuclear Medicine Department, Azienda Ospedaliero Universitaria di Bologna Policlinico S Orsola Malpighi, Italy
Nucl Med Commun 28:547-53. 2007..The aim of our study was to compare the retro-orbital (RO) versus tail vein intravenous (i.v.) administration of (18)F-FDG and (11)C-choline in mice for small-animal PET studies...
Epithelial and mesenchymal tumor compartments exhibit in vivo complementary patterns of vascular perfusion and glucose metabolismMirco Galiè
Dipartimento Scienze Morfologico Biomediche, sez Anatomia ed Istologia, Universita di Verona, Verona, Italy
Neoplasia 9:900-8. 2007..Our results suggests that FDG-PET-based clinical analysis can underestimate the malignity or tumor extension of carcinomas exhibiting any trait of "mesenchymalization" such as desmoplasia or epithelial-mesenchymal transition...
Is there an ideal diagnostic algorithm in solitary pulmonary nodules?Valentina Ambrosini
Respiration 73:587-9. 2006
