Research Topics
| Sandra MontiSummaryAffiliation: Unit of Bologna Country: Italy Publications
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Detail Information
Publications
Interaction of 4-hydroxybiphenyl with cyclodextrins: effect of complex structure on spectroscopic and photophysical propertiesP Bortolus
Istituto di Fotochimica e Radiazioni d Alta Energia, CNR Area della Ricerca, Bologna, Italy
Chemistry 6:1578-91. 2000..Triplet-triplet absorption and triplet quenching data supported this interpretation. The photophysical properties of both the 1:1 and the 2:2 complexes are characterized by a significant reduction of the nonradiative decay rates...
Multifaceted photoreactivity of 6-fluoro-7-aminoquinolones from the lowest excited states in aqueous media: a study by nanosecond and picosecond spectroscopic techniquesS Monti
Istituto di Fotochimica e Radiazioni d Alta Energia CNR, Bologna, Italy
Chemistry 7:2185-96. 2001..The correlation between the transients observed and the final photoproducts in the different media was elucidated...
Photoprocesses of photosensitizing drugs within cyclodextrin cavitiesSandra Monti
Istituto per la Sintesi Organica e la Fotoreattività del CNR, Area della Ricerca, Via Piero Gobetti 101, I 40129 Bologna, Italy
Chem Soc Rev 31:287-300. 2002..The limitations for the use of CDs as protective systems for the clinical administration of photosensitising drugs is also evidenced...
Laser flash photolysis study of photoionization in fluoroquinolonesSandra Monti
Istituto per la Sintesi Organica e la Fotoreattivita, CNR, Area della Ricerca, Via Piero Gobetti 101, I 40129 Bologna, Italy
Photochem Photobiol Sci 1:877-81. 2002..With rufloxacin, besides the two-photon process, a one photon contribution with a quantum yield of 0.034 was measured...
Binding of a chiral drug to a protein: an investigation of the 2-(3-benzoylphenyl)propionic acid/bovine serum albumin system by circular dichroism and fluorescenceSandra Monti
Istituto per la Sintesi Organica e la Fotoreattivita ISOF, CNR Area della Ricerca, Via P Gobetti 101, 40129 Bologna, Italy
Phys Chem Chem Phys 7:4002-8. 2005....
Complexes of the antitumoral drugs Doxorubicin and Sabarubicin with telomeric G-quadruplex in basket conformation: ground and excited state propertiesIlse Manet
Istituto per la Sintesi Organica e la Fotoreattivita, Consiglio Nazionale delle Ricerche, Via Gobetti 101, I 40129, Bologna, Italy
Photochem Photobiol Sci 10:1326-37. 2011..The experimental CD spectra combined with conformational calculations at MM level and quantum mechanical calculation of the rotational strength of the electronic transitions afforded information on the binding geometries...
Structure and properties of licochalcone A-human serum albumin complexes in solution: a spectroscopic, photophysical and computational approach to understand drug-protein interactionSandra Monti
Istituto per la Sintesi Organica e la Fotoreattivita, Consiglio Nazionale delle Ricerche, Via Gobetti 101, Bologna, I 40129
Phys Chem Chem Phys 10:6597-606. 2008..The overall rigidity of the structure causes a lengthening of the triplet lifetime...
Binding and photochemistry of enantiomeric 2-(3-benzoylphenyl)propionic acid (ketoprofen) in the human serum albumin environmentSandra Monti
Istituto per la Sintesi Organica e la Fotoreattivita ISOF, CNR, Via P Gobetti 101, 40129, Bologna, Italy
Photochem Photobiol Sci 6:462-70. 2007..7-0.9). Secondary transients were consistent with the occurrence of photodecarboxylation and/or photoreduction within the protein matrix...
Chiral recognition of 2-(3-benzoylphenyl)propionic acid (ketoprofen) by serum albumin: an investigation with microcalorimetry, circular dichroism and molecular modellingSandra Monti
Istituto per la Sintesi Organica e la Fotoreattivita, Consiglio Nazionale delle Ricerche CNR, Via Gobetti 101, I 40129 Bologna, Italy
Phys Chem Chem Phys 11:9104-13. 2009..The same sites are involved in the formation of 2:1 complexes. The equilibrium structures are characterized by marked geometrical distortion of KP...
Stereoselective interaction of ketoprofen enantiomers with ?-cyclodextrin: ground state binding and photochemistryGiancarlo Marconi
Istituto per la Sintesi Organica e la Fotoreattivita, Consiglio Nazionale delle Ricerche, Via Piero Gobetti 101, I 40129, Bologna, Italy
Photochem Photobiol Sci 10:48-59. 2011....
Licochalcone A bound to bovine serum albumin: a spectroscopic, photophysical and structural studySandra Monti
Istituto per la Sintesi Organica e la Fotoreattivita, Consiglio Nazionale delle Ricerche, I 40129 Bologna, Italy
Photochem Photobiol Sci 8:805-13. 2009..MM and MD calculations also showed LA associates in domain III, the lowest energy complex being one with the drug close to Tyr409...
Combination of spectroscopic and computational methods to get an understanding of supramolecular chemistry of drugs: from simple host systems to biomoleculesSandra Monti
Istituto per la Sintesi Organica e la Fotoreattivita, ISOF CNR, Via Piero Gobetti 101, 40129 Bologna, Italy
Phys Chem Chem Phys 13:20893-905. 2011....
Gaining an insight into the photoreactivity of a drug in a protein environment: a case study on nalidixic acid and serum albuminSandra Monti
Istituto per la Sintesi Organica e la Fotoreattivita, CNR, Via P Gobetti 101, 40129 Bologna, Italy
J Phys Chem B 112:5742-54. 2008..Decay of the confined radical pairs occurred with rates approximately 10(7) s(-1). Formation of covalent drug-protein adducts in mixtures irradiated at lambdairr> 324 nm was proved using HPLC with fluorescence detection...
A cationic Zn(II) porphyrazine induces a stable parallel G-quadruplex conformation in human telomeric DNAIlse Manet
Istituto per la Sintesi Organica e la Fotoreattivita, Consiglio Nazionale delle Ricerche, Via Gobetti 101, 40129 Bologna, Italy
Org Biomol Chem 9:684-8. 2011..A water soluble Zn(II) porphyrazine drives the conformational equilibrium of the G-quadruplex of a human telomeric sequence exclusively towards a parallel conformation upon complexation...
Affinity of the anthracycline antitumor drugs Doxorubicin and Sabarubicin for human telomeric G-quadruplex structuresIlse Manet
Istituto per la Sintesi Organica e la Fotoreattivita, Consiglio Nazionale delle Ricerche, Via Piero Gobetti 101, I 40129 Bologna, Italy
Phys Chem Chem Phys 13:540-51. 2011..Complexation caused a small increase in the thermal stability of the G-quadruplex main conformation, shifting T(m) from 62 to 67 °C...
Revealing phenylium, phenonium, vinylenephenonium, and benzenium ions in solutionIlse Manet
Istituto per la Sintesi Organica e la Fotoreattivita ISOF, CNR Area della Ricerca, Via P Gobetti 101, 40129 Bologna, Italy
Chemistry 14:1029-39. 2008..The final products were anisylhexyne and methoxybiphenyl (an analogous product and intermediate were detected with thiophene)...
Diastereoselectivity and site dependency in the photochemistry of ketoprofen in the bovine serum albumin matrixSandra Monti
Istituto per la Sintesi Organica e la Fotoreattivita ISOF, CNR, Via P Gobetti 101, 40129 Bologna, Italy
Photochem Photobiol 82:13-9. 2006..The photoreactivity in the BSA matrix was rationalized on the basis of diastereoselective photodecarboxylation in the two main protein sites...
Photoisomerization and photo-hydration of 3-hydroxystyrylnaphthalenesElisa Bandini
, Via Piero Gobetti 101, 40129, Bologna, Italy
Photochem Photobiol Sci 4:862-8. 2005....
Change in conformation with reduction of alpha-helix content causes loss of neutrophil binding activity in fully cytotoxic Shiga toxin 1Maurizio Brigotti
Dipartimento di Patologia Sperimentale, Universita di Bologna, Bologna, Italy
J Biol Chem 286:34514-21. 2011....
Modeling the photochemistry of the reference phototoxic drug lomefloxacin by steady-state and time-resolved experiments, and DFT and post-HF calculationsMauro Freccero
Department of Organic Chemistry, University of Pavia, Via Taramelli 10, 27100 Pavia, Italy
Chemistry 14:653-63. 2008..These findings suggest that the mutagenic activity of the DNA-intercalated drug involves attack of the photogenerated cation to the heterocyclic bases...
Photophysics and photochemistry of fluoroquinolonesAngelo Albini
Dipartimento di Chimica Organica, Universita di Pavia, Viale Taramelli 10, I 27100, Italy
Chem Soc Rev 32:238-50. 2003..The results can help in the understanding of the photochemistry occurring in biological environments and in the assessing of the correlation between structural characteristics and biological photodamage...
