Research Topics
| Luigi Ferini-StrambiSummaryAffiliation: San Raffaele Scientific Institute Country: Italy Publications
| Collaborators
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Detail Information
Publications
Snoring & sleep apnea: a population study in Italian womenL Ferini-Strambi
Sleep Disorders Center, State University and IRCCS H San Raffaele, Milan, Italy
Sleep 22:859-64. 1999..We concluded that in middle-aged women, both snoring and sleep apnea are very common. A high percentage of snoring is not essential for the occurrence of sleep apnea, nor it necessarily indicates the presence of sleep apnea...- Increased periodic arousal fluctuations during non-REM sleep are associated to superior memoryLuigi Ferini-Strambi
Sleep Disorders Center, Scientific Institute H San Raffaele, University Vita Salute San Raffaele, Via Stamina d Ancona 20, 20127 Milano, Italy
Brain Res Bull 63:439-42. 2004..D. units above that observed in age-matched controls). Since CAP rate reflects the structural organization of non-REM sleep, this observation supports the hypothesis of a link between non-REM sleep and declarative memory performance... - Treatment of restless legs syndromeLuigi Ferini-Strambi
Sleep Disorders Center, Department of Neuroscience, Universita Vita Salute San Raffaele, Milan, Italy
Parkinsonism Relat Disord 15:S65-70. 2009..Pharmacological treatment should be limited to those patients who suffer from clinically relevant RLS with impaired sleep quality or quality of life. Treatment on demand is a clinical need in RLS cases that present intermittent symptoms... - Effects of reboxetine on sleep and nocturnal cardiac autonomic activity in patients with dysthymiaLuigi Ferini-Strambi
Sleep Disorders Center, Universita Vita Salute, IRCCS H San Raffaele, Italy
J Psychopharmacol 18:417-22. 2004..Long-term treatment with 4 mg reboxetine does not cause significant changes in cardiac autonomic function... - Genetics in restless legs syndromeLuigi Ferini-Strambi
Sleep Disorders Center, University Vita Salute San Raffaele and Human Molecular Genetics Unit, Dibit San Raffaele Hospital, Via Stamina d Ancona 20, 20122 Milano, Italy
Sleep Med 5:301-4. 2004..However, the efforts toward the identification of RLS genes must continue in order to obtain a better characterization of the syndrome and to identify new therapeutic strategies... - Epidemiology of obstructive sleep apnea syndromeL Ferini-Strambi
Department of Neurology, Sleep Disorders Center, Vita Salute University, San Raffaele Hospital, Via Stamira d Ancona 20, 20127 Milan, Italy
Minerva Med 95:187-202. 2004.... - Neuropsychological assessment in idiopathic REM sleep behavior disorder (RBD): does the idiopathic form of RBD really exist?L Ferini-Strambi
Sleep Disorders Center, Universita Vita Salute San Raffaele, Milano, Italy
Neurology 62:41-5. 2004..To evaluate the cognitive performance of patients with idiopathic REM sleep behavior disorder (RBD)... - Treatment options for restless legs syndromeLuigi Ferini-Strambi
Universita Vita Salute San Raffaele, Sleep Disorders Center, Milan, Italy
Expert Opin Pharmacother 10:545-54. 2009..Dopaminergic agents are the best-studied agents, and are considered first-line treatment of RLS... - RLS-like symptoms: differential diagnosis by history and clinical assessmentLuigi Ferini-Strambi
Sleep Disorders Center, Universita Vita Salute San Raffaele, Via Stamira d Ancona 20, 20127 Milan, Italy
Sleep Med 8:S3-6. 2007.... - REM sleep behaviour disorderL Ferini-Strambi
Sleep Disorders Center, Department of Neurology, Universita Vita Salute San Raffaele, Via Stamira d Ancona 20, I 20127 Milan, Italy
Neurol Sci 26:s186-92. 2005..The detection of early markers of neurodegenerative disorders in idiopathic RBD, and the evaluation of their value by the combined application in prospective studies may be crucial for developing early intervention strategies... - Cognitive dysfunction in patients with obstructive sleep apnea (OSA): partial reversibility after continuous positive airway pressure (CPAP)L Ferini-Strambi
Sleep Disorders Center, Universita Vita Salute San Raffaele, Via Stamira d Ancona 20, 20127 Milano, Italy
Brain Res Bull 61:87-92. 2003..The findings of this study confirm the hypothesis of partial reversibility of cognitive dysfunction in OSA patients after CPAP... - The impact of cyclic alternating pattern on heart rate variability during sleep in healthy young adultsL Ferini-Strambi
Sleep Disorders Center, University of Milano and IRCCS H San Raffaele, Milan, Italy
Clin Neurophysiol 111:99-101. 2000..The aim of our study was to evaluate HR variability in relation to CAP during non-REM sleep in healthy adults... - REM sleep behavior disorderL Ferini-Strambi
Sleep Disorders Center, Istituto Scientifico H San Raffaele, Via Prinetti 27, 20127, Milano, Italy
Clin Neurophysiol 111:S136-40. 2000..Most importantly, RBD is readily diagnosable and treatable. Patients and their bed partners usually report immediate improvement in sleep-related motor behavior with small doses of clonazepam... - Cerebrovascular diseases and sleep-disordered breathingLuigi Ferini-Strambi
Dept of Neurology, Sleep Disorders Center, Universita Vita Salute San Raffaele, Milan, Italy
Clin Exp Hypertens 28:225-31. 2006..Specific treatment of SDB may reduce the possibility of further cerebrovascular disturbances... - Does idiopathic REM sleep behavior disorder (iRBD) really exist? What are the potential markers of neurodegeneration in iRBD?Luigi Ferini-Strambi
Sleep Disorders Center, Vita Salute San Raffaele University, Milan, Italy
Sleep Med 12:S43-9. 2011.... - First night efficacy of pramipexole in restless legs syndrome and periodic leg movementsMauro Manconi
Sleep Disorders Center, Department of Neurology, Scientific Institute and University Ospedale San Raffaele, Vita Salute University, Milan, Italy
Sleep Med 8:491-7. 2007..Restless legs syndrome (RLS) seems to improve immediately after a single dose of dopamine-agonists (DA). The aim of the present study was to investigate the acute effects of a low standard dose of pramipexole in RLS drug-naïve patients... - Autosomal dominant restless legs syndrome maps on chromosome 14qMaria Teresa Bonati
Human Molecular Genetics Unit, Department of Neuroscience, DIBIT San Raffaele Scientific Institute, Milan, Italy
Brain 126:1485-92. 2003..The complementary clinical and genetic studies on multiplex families are likely to be of the utmost importance in unfolding the complete expressivity of RLS phenotype spectrum... - Nocturnal eating: sleep-related eating disorder or night eating syndrome? A videopolysomnographic studyRoberto Vetrugno
Sleep Disorders Center, Department of Neurological Sciences, University of Bologna, Italy
Sleep 29:949-54. 2006..To describe the clinical and videopolysomnographic characteristics of nocturnal eating episodes in sleep-related eating disorder... - Longitudinal study of cognitive function in idiopathic REM sleep behavior disorderMaria Livia Fantini
Sleep Disorders Center, Universita Vita Salute San Raffaele, Milan, Italy
Sleep 34:619-25. 2011..To assess the longitudinal course of cognitive functions in a cohort of patients with idiopathic REM sleep behavior disorder (iRBD)... - Time structure analysis of leg movements during sleep in REM sleep behavior disorderMauro Manconi
Sleep Disorders Center, Department of Neurology, H San Raffaele Scientific Institute, Universita Vita Salute San Raffaele, Milan, Italy
Sleep 30:1779-85. 2007..To compare the time structure of leg movements (LM) during sleep of patients with rapid eye movement (REM) sleep behavior disorder (RBD) with that of patients with restless legs syndrome (RLS) or control subjects... - Effects of acute dopamine-agonist treatment in restless legs syndrome on heart rate variability during sleepMauro Manconi
Sleep Disorders Center, Department of Neuroscience, Scientific Institute and University Ospedale San Raffaele, Vita Salute University, Milan, Italy
Sleep Med 12:47-55. 2011..To compare heart rate variability (HRV) changes in patients with restless legs syndrome (RLS) and in healthy subjects, and to evaluate HRV before and after treatment with pramipexole in RLS patients... - Event-related potentials in idiopathic rapid eye movements sleep behaviour disorderAlberto Raggi
Department of Neurology and Neurorehabilitation, San Raffaele Turro Hospital, Via Stamira d Ancona 20, 20127 Milan, Italy
Clin Neurophysiol 118:669-75. 2007..To assess psychophysiological parameters in idiopathic rapid eye movements sleep behaviour disorder (RBD), in order to identify possible markers for pre or sub-clinical cognitive abnormalities... - Topiramate treatment for nocturnal frontal lobe epilepsyAlessandro Oldani
Sleep Disorders Center, Department of Neurology, HSR Turro and Università Vita Salute San Raffaele, Milan, Italy
Seizure 15:649-52. 2006..Aim of this study was to evaluate the efficacy and tolerability of the antiepileptic drug topiramate (TPM) in a sample of patients with nocturnal frontal lobe epilepsy (NFLE)... - Prevalence of habitual snoring and sleep-disordered breathing in preschool-aged children in an Italian communityVincenza Castronovo
Sleep Disorders Center, IRCCS H San Raffaele, Milano, Italy
J Pediatr 142:377-82. 2003..To measure the prevalence of habitual snoring and sleep-disordered breathing in preschool-aged children... - Measuring the error in sleep estimation in normal subjects and in patients with insomniaMauro Manconi
Sleep Disorders Center, Department of Neuroscience, Scientific Institute and University Ospedale San Raffaele, Vita Salute University, Milan, Italy
J Sleep Res 19:478-86. 2010..The MI gives a reliable and immediate description of sleep misperception in healthy and insomnia subjects. Its application supports the existence of the high misperception of insomnia as a separate pathological entity... - Defining the boundaries of the response of sleep leg movements to a single dose of dopamine agonistMauro Manconi
Sleep Disorders Center, Department of Neurology, Scientific Institute and University Ospedale San Raffaele, Vita Salute University, Milan, Italy
Sleep 31:1229-37. 2008..To define which leg movements (LM) associated with restless legs syndrome (RLS) respond to dopamine-agonist treatment and verify if they fall within current diagnostic criteria for periodic LM during sleep (PLMS)... - The official World Association of Sleep Medicine (WASM) standards for recording and scoring periodic leg movements in sleep (PLMS) and wakefulness (PLMW) developed in collaboration with a task force from the International Restless Legs Syndrome Study GrouMarco Zucconi
Sleep Disorders Center, San Raffaele Hospital, Milano, Italy
Sleep Med 7:175-83. 2006 - Studio Morfeo: insomnia in primary care, a survey conducted on the Italian populationMario Giovanni Terzano
Sleep Disorders Center, University of Parma, Via del Quartiere 4, Parma 43100, Italy
Sleep Med 5:67-75. 2004.... - Case of symptomatic propriospinal myoclonus evolving toward acute "myoclonic status"Mauro Manconi
Department of Neurology, Vita Salute University, Istituto di Ricovero e Cura a Carattere Scientifico San Raffaele Turro, Milan, Italy
Mov Disord 20:1646-50. 2005..It is necessary to consider this severe progression and support it with prompt emergency maneuvers and adequate pharmacotherapy... - Pramipexole versus ropinirole: polysomnographic acute effects in restless legs syndromeMauro Manconi
Department of Neurology, Sleep Disorders Center, Scientific Institute and University Ospedale San Raffaele, Vita Salute University, Milan, Italy
Mov Disord 26:892-5. 2011..Pramipexole and ropinirole have become the first-line treatment for restless legs syndrome. The aim of this study was to perform the first direct comparison between these two molecules in restless legs syndrome... - Cabergoline is an effective single-drug treatment for restless legs syndrome: clinical and actigraphic evaluationMarco Zucconi
Sleep Disorders Center, Department of Neurology, H San Raffaele Scientific Institute and Hospital, Universita Vita Salute San Raffaele, Milan, Italy
Sleep 26:815-8. 2003..To evaluate the efficacy and the safety of cabergoline, a dopamine-receptor agonist with a long half-life, in restless legs syndrome (RLS)... - Association between bruxism and nocturnal groaningMauro Manconi
Center of Sleep Medicine, Department of Neurology, Scientific Institute of San Raffaele, Milan, Italy
Mov Disord 23:737-9. 2008..The hypothesis of a common trigger mechanism for NG and bruxism, through an arousal-induced activation, is discussed... - Frontal lobe epilepsy and mutations of the corticotropin-releasing hormone geneRomina Combi
Department of Biology and Genetics for Medical Sciences, University of Milan, Milan, Italy
Ann Neurol 58:899-904. 2005..In vitro experiments showed altered levels of gene expression. CRH alterations could explain several autosomal dominant nocturnal frontal lobe epilepsy clinical features... - Multicenter case-control study on restless legs syndrome in multiple sclerosis: the REMS studyMauro Manconi
Sleep Disorders Center, Scientific Institute and Ospedale San Raffaele, Via Stamira d Ancona 20, 20127 Milan, Italy
Sleep 31:944-52. 2008..To verify the existence of a symptomatic form of restless legs syndrome (RLS) secondary to multiple sclerosis (MS) and to identify possible associated risk factors... - Obstructive sleep apnea: brain structural changes and neurocognitive function before and after treatmentNicola Canessa
Center for Cognitive Neuroscience, Vita Salute San Raffaele University, Milan, Italy
Am J Respir Crit Care Med 183:1419-26. 2011..Knowledge of the brain structures involved in OSA and the corresponding functional implications could provide clues to the pathogenesis of cognitive impairment and its reversibility in this disorder... - Effect of pramipexole on RLS symptoms and sleep: a randomized, double-blind, placebo-controlled trialLuigi Ferini-Strambi
Institute San Raffaele Turro, Milan, Italy
Sleep Med 9:874-81. 2008..Our goal was to test the ability of pramipexole to improve sleep in RLS patients and to reconfirm its efficacy for primary RLS symptoms... - Olfactory deficit in idiopathic rapid eye movements sleep behavior disorderMaria Livia Fantini
Sleep Disorders Center, Department of Neurology, Universita Vita Salute San Raffaele, via Stamira d Ancona n 20, 20127 Milan, Italy
Brain Res Bull 70:386-90. 2006..Pathological changes in the anterior olfactory nucleus and olfactory loss occur very early in the course of PD and DLB. The aim of the study was to assess olfactory function in a large group of idiopathic RBD patients... - Multivariate and multiorgan analysis of cardiorespiratory variability signals: the CAP sleep caseAnna M Bianchi
Department of Biomedical Engineering, Polytechnic University of Milano, Milano, Italy
Biomed Tech (Berl) 51:167-73. 2006..During 2 CAP MC, the increased synchronization involved myoclonus and respiration. The underlying mechanism seems to be related to a global control system at the central level that involves the different systems... - Respiratory monitoring by means of an unattended device in children with suspected uncomplicated obstructive sleep apnea: a validation studyMarco Zucconi
Sleep Disorders Center, Department of Neurology, and Statistic Unit, IRCCS H San Raffaele, Milan, Italy
Chest 124:602-7. 2003..To compare an unattended device for cardiorespiratory monitoring (POLY-MESAM; MAP; Martinsried, Germany) [P-M] with classic nocturnal polysomnography (PSG) for diagnosis of obstructive sleep apnea (OSA) in children... - Epidemiology and clinical findings of restless legs syndromeMarco Zucconi
Department of Neurology, Sleep Disorders Center, H San Raffaele Scientific Institute, Universita Vita Salute San Raffaele, Via Stamira d Ancona 20, 20 127 Milan, Italy
Sleep Med 5:293-9. 2004.... - Studio Morfeo 2: survey on the management of insomnia by Italian general practitionersMario Giovanni Terzano
Department of Neuroscience, Sleep Disorders Center, University of Parma, Via Gramsci, 14, 43100 Parma, Italy
Sleep Med 7:599-606. 2006..To carry out an observational epidemiological survey (Studio Morfeo 2) in order to define the management procedures of insomnia in a large Italian population presenting directly to the general practitioner (GP)... - Expression of mutant beta2 nicotinic receptors during development is crucial for epileptogenesisIrene Manfredi
San Raffaele Scientific Institute, Milan, Italy
Hum Mol Genet 18:1075-88. 2009..Our data indicate that mutant nicotinic receptors are responsible for abnormal formation of neuronal circuits and/or long-lasting alteration of network assembly in the developing brain, thus leading to epilepsy... - The behavioural features of fatal familial insomnia: A new Italian case with pathological verificationAlberto Raggi
Department of Clinical Neurosciences, San Raffaele Turro Hospital, 20127 Milan, Italy
Sleep Med 10:581-5. 2009..We report a new, pathologically verified Italian case of fatal familial insomnia, whose clinical presentation was characterised by complex behavioural disturbances, suggesting wakefulness/NREM/REM combinations... - Response to Clinical Corners case (Sleep Medicine 6/2: 83-4): Pregnancy associated with daytime sleepiness and nighttime restlessnessMauro Manconi
Department of Neurology, Sleep Disorders Center, Vita-Salute University, IRCCS H S. Raffaele, Milan, Italy
Sleep Med 6:477-8. 2005 - Autosomal dominant nocturnal frontal lobe epilepsy--a critical overviewRomina Combi
Department of Biology and Genetics for, Medical Sciences University of Milan, Via Viotti 3/5, 20133, Milan, Italy
J Neurol 251:923-34. 2004..This is an overview on the clinical and genetic aspects of ADNFLE including a discussion of some open questions on the role of the neuronal nicotinic receptor subunit mutations in the pathogenesis of this form of epilepsy... - Sleep in genetically confirmed pantothenate kinase-associated neurodegeneration: a video-polysomnographic studyMaria Livia Fantini
Sleep Disorders Center, Department of Clinical Neurosciences, Vita Salute San Raffaele University, H San Raffaele Turro, 20127 Milan, Italy
Parkinsons Dis 2010:342834. 2010..Sleep studies may phenotypically differentiate PKAN from other neurodegenerative disorders... - A quantitative statistical analysis of the submentalis muscle EMG amplitude during sleep in normal controls and patients with REM sleep behavior disorderRaffaele Ferri
Sleep Research Centre, Department of Neurology I C, Oasi Institute IRCCS, Troina, Italy
J Sleep Res 17:89-100. 2008.... - Catathrenia (nocturnal groaning): what is it?Roberto Vetrugno
Department of Neurological Sciences, University of Bologna, Bologna, Italy
Sleep 31:308-9. 2008 - Efficacy of rotigotine for treatment of moderate-to-severe restless legs syndrome: a randomised, double-blind, placebo-controlled trialClaudia Trenkwalder
Paracelsus Elena Hospital, Kassel, Germany
Lancet Neurol 7:595-604. 2008..Continuous administration of a dopamine agonist could be used to treat patients with restless legs syndrome. Our aim was to investigate the efficacy of transdermal rotigotine in the treatment of idiopathic restless legs syndrome... - Parkinsonism with excessive daytime sleepiness--a narcolepsy-like disorder?Christian Baumann
Neurologische Poliklinik, , Frauenklinikstrasse 26, , Switzerland
J Neurol 252:139-45. 2005..Sleep apnea and PLMS may play a so-far underestimated role in the pathogenesis of EDS in Parkinsonian patients... - Health-related quality of life in Italian patients with narcolepsy: the SF-36 health surveyLuca Vignatelli
Dipartimento di Scienze Neurologiche, , Via Ugo Foscolo 7, 40123 Bologna, Italy
Sleep Med 5:467-75. 2004..EDS is the main symptom determining this impairment. However, disease duration plays a role in counterbalancing this feature, probably by means of adaptation... - Emotional information processing in patients with narcolepsy: a psychophysiologic investigationValter Tucci
Department of Psychology, University of Padua, Padua, Italy
Sleep 26:558-64. 2003..The drawback exhibited by these patients suggests reduced reactivity of the aversive motivational system responsible for negative or unpleasant emotions... - Impact, diagnosis and treatment of restless legs syndrome (RLS) in a primary care population: the REST (RLS epidemiology, symptoms, and treatment) primary care studyWayne Hening
Department of Neurology, Robert Wood Johnson Medical School, University of Medicine and Dentistry of New Jersey, New Brunswick, NJ, USA
Sleep Med 5:237-46. 2004..To assess the frequency, impact, and medical response to the restless legs syndrome (RLS) in a large multi-national primary care population... - Computer-assisted detection of nocturnal leg motor activity in patients with restless legs syndrome and periodic leg movements during sleepRaffaele Ferri
Sleep Research Centre, Department of Neurology I C, Oasi Institute IRCCS, Troina, Italy
Sleep 28:998-1004. 2005..To assess the performance of a new method for automatic detection of periodic leg movements during sleep... - NREM sleep alterations in narcolepsy/cataplexyRaffaele Ferri
Department of Neurology IC, Sleep Research Centre, Oasi Institute IRCCS, Troina, Enna, Italy
Clin Neurophysiol 116:2675-84. 2005..NREM sleep patterns of narcoleptic patients with cataplexy were studied, focusing on their sleep 'microstructure', by analyzing the cyclic alternating pattern (CAP)... - Different periodicity and time structure of leg movements during sleep in narcolepsy/cataplexy and restless legs syndromeRaffaele Ferri
Sleep Research Centre, Department of Neurology I C, Oasi Institute for Research on Mental Retardation and Brain Aging IRCCS, Troina, Italy
Sleep 29:1587-94. 2006..To analyze periodic leg movements (PLM) during sleep in patients with narcolepsy and compare the results with those obtained in normal controls and subjects with restless legs syndrome (RLS)... - Heart rate and spectral EEG changes accompanying periodic and non-periodic leg movements during sleepRaffaele Ferri
Sleep Research Centre, Department of Neurology I C, Oasi Institute IRCCS, 94018 Troina, Italy
Clin Neurophysiol 118:438-48. 2007..To evaluate the changes in heart rate (HR) and EEG spectra accompanying periodic (PLM) and non-periodic leg movements (NPLM) during sleep in patients with restless legs syndrome (RLS)... - New approaches to the study of periodic leg movements during sleep in restless legs syndromeRaffaele Ferri
Sleep Research Centre, Department of Neurology I C, Oasi Institute for Research on Mental Retardation and Brain Aging IRCCS, Troina, Italy
Sleep 29:759-69. 2006..To describe a new approach for the analysis of quantity, type, and periodicity of the leg motor activity during sleep in patients with restless legs syndrome (RLS) and periodic leg movements (PLM)... - Restless legs syndrome among pregnant womenMauro Manconi
Sleep 27:350; author reply 351. 2004 - Genetics of restless legs syndromeJuliane Winkelmann
Institute of Human Genetics, GSF National Research Center for Environment and Health, Ingolstadter Landstrasse 1, D 85764 Munich Neuherberg, Germany
Sleep Med Rev 10:179-83. 2006..It is important to investigate whether further RLS families show linkage to one of these loci to discuss the contribution of these loci and to provide a prerequisite of a mutational screening and identification of the RLS genes... - Pramipexole in Restless Legs syndrome. Evaluation by suggested immobilization testMauro Manconi
J Neurol 250:1494-5. 2003 - Sleep and quantitative EEG in neurodegenerative disordersDominique Petit
, , , , Canada
J Psychosom Res 56:487-96. 2004..The study of sleep variables and that of the spectral composition of the EEG can provide valuable information for understanding the pathophysiology and for assisting the diagnosis of neurodegenerative diseases... - Evidence for a fourth locus for autosomal dominant nocturnal frontal lobe epilepsyRomina Combi
Department of Biology and Genetics for Medical Sciences, University of Milan, Via Viotti 3/5, 20133 Milan, Italy
Brain Res Bull 63:353-9. 2004..These data strongly suggest that ENFL1, ENFL2 and ENFL3 are minor loci for the disease and point to the existence of at least a fourth locus for ADNFLE... - Exclusion of linkage of nine neuronal nicotinic acetylcholine receptor subunit genes expressed in brain in autosomal dominant nocturnal frontal lobe epilepsy in four unrelated familiesMaria Teresa Bonati
Department of Biology and Genetics for Medical Sciences, University of Milan, via Viotti 3 5, 20133 Milan, Italy
J Neurol 249:967-74. 2002..These findings support the hypothesis that genes different from those coding for alpha2-7 and beta2-4 neuronal nAChR subunits could be responsible for ADNFLE... - Family-based association study of the restless legs syndrome loci 2 and 3 in a European populationDavid Kemlink
Institute of Human Genetics, GSF National Research Center for Environment and Health, Munich, Germany
Mov Disord 22:207-12. 2007..0077, respectively). These results represent the first confirmation of these loci in a mixed European population. Variable results observed in families of different ethnic groups further corroborate the genetic complexity of RLS... - Restless legs syndrome: prevalence and impact in children and adolescents--the Peds REST studyDaniel Picchietti
University of Illinois School of Medicine and Carle Clinic Association, Department of Pediatrics, 602 W University Ave, Urbana, IL 61801, USA
Pediatrics 120:253-66. 2007..In this first population-based study to use specific pediatric diagnostic criteria, we examined the prevalence and impact of restless legs syndrome in 2 age groups: 8 to 11 and 12 to 17 years... - Burden of restless legs syndrome on health-related quality of lifeClete Kushida
Stanford Center of Excellence for Sleep Disorders, Stanford, CA, USA
Qual Life Res 16:617-24. 2007..To quantify the total and unique burden of Restless Legs Syndrome (RLS) on patient-reported health-related quality of life (HRQoL)... - Left thalamomegaly in a patient with partial epilepsyGiacomo Della Marca
Department of Neurosciences, Catholic University, Rome, Italy
Clin Neurol Neurosurg 110:298-301. 2008..18-FDG PET showed reduced metabolic activity in the upper right temporal gyrus and in the ipsilateral thalamus. Thalamic asymmetry in our patient could be an occasional finding... - Validation of the Augmentation Severity Rating Scale (ASRS): a multicentric, prospective study with levodopa on restless legs syndromeDiego Garcia-Borreguero
Fundacion Jimenez Diaz, Madrid, Spain
Sleep Med 8:455-63. 2007..The changes in each dimension are summed to give an ASRS total score... - Two new putative susceptibility loci for ADNFLERomina Combi
Department of Biology and Genetics for Medical Sciences, University of Milano, Italy
Brain Res Bull 67:257-63. 2005..In particular, we propose and discuss the hypothesis of a digenic transmission of the disease... - Clinical trials in restless legs syndrome--recommendations of the European RLS Study Group (EURLSSG)Claudia Trenkwalder
Paracelsus Elena Hospital, Center of Parkinsonism and Movement Disorders, Klinikstr 16, 34128 Kassel, Germany
Mov Disord 22:S495-504. 2007..The aim of these recommendations is to support research groups or pharmaceutical companies in the design of optimized study protocols... - State of the art in restless legs syndrome therapy: practice recommendations for treating restless legs syndromeWolfgang H Oertel
Department of Neurology, Philipps University, Marburg, Germany
Mov Disord 22:S466-75. 2007..Opioids and anticonvulsants such as gabapentine are second-line options in individual patients. Iron substitution is justified in people with iron deficiency related RLS (ferritin concentration lower than 50 microg/L)... - Sleep disturbances and teacher ratings of school achievement and temperament in childrenOliviero Bruni
Department of Developmental Neurology and Psychiatry, Center for Pediatric Sleep Disorders, University of Rome La Sapienza, Via dei Sabelli 108, 00185 Rome, Italy
Sleep Med 7:43-8. 2006..The current study examined the relationships between academic achievement, sleep, temperament and demographic-historical data in school-age children... - Restless legs syndrome prevalence and impact: REST general population studyRichard P Allen
Department of Neurology, The Johns Hopkins University, Baltimore, MD 21224, USA
Arch Intern Med 165:1286-92. 2005..Previous epidemiological studies, however, have failed to determine the prevalence of those with clinically significant RLS symptoms and to examine the life effects and medical experiences of this group... - Idiopathic REM sleep behavior disorder: toward a better nosologic definitionMaria Livia Fantini
, , , Canada
Neurology 64:780-6. 2005..Identifying subjects with a high risk of developing a neurodegenerative process may be crucial in order to develop early intervention strategies... - Mutational analysis of nicotinic acetylcholine receptor beta2 subunit gene (CHRNB2) in a representative cohort of Italian probands affected by autosomal dominant nocturnal frontal lobe epilepsyStefano Duga
Department of Biology and Genetics for Medical Sciences, University of Milan, Via Viotti, 3 5 20133 Milan, Italy
Epilepsia 43:362-4. 2002..In none of the patients were mutations in the analyzed region of CHRNB2 found. These data, obtained in the largest ADNFLE cohort so far analyzed, demonstrate the rarity of the identified CHRNB2 mutations in ADNFLE patients...