Research Topics
Species | G L CeresoliSummaryAffiliation: San Raffaele Scientific Institute Country: Italy Publications
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Detail Information
Publications
Gefitinib in patients with brain metastases from non-small-cell lung cancer: a prospective trialG L Ceresoli
Department of Oncology, Scientific Institute San Raffaele, Milan
Ann Oncol 15:1042-7. 2004..The aim of this study was to evaluate the activity and safety of gefitinib in NSCLC patients with brain metastases...
Brain metastases in locally advanced nonsmall cell lung carcinoma after multimodality treatment: risk factors analysisGiovanni Luca Ceresoli
Department of Radiochemotherapy, IRCCS San Raffaele, Via Olgettina 60, 02132 Milan, Italy
Cancer 95:605-12. 2002..New treatment and follow-up strategies are needed to reduce the risk of BM and to diagnose them early enough for effective treatment...
Phase II study of weekly paclitaxel as second-line therapy in patients with advanced non-small cell lung cancerGiovanni Luca Ceresoli
Department of Oncology, Scientific Institute San Raffaele, Via Olgettina, 60 20132 Milan, Italy
Lung Cancer 44:231-9. 2004..Patients with PS 0-1, non-squamous histology and with no progression within 4 months of first line cisplatin-based chemotherapy seem more likely to benefit from this treatment...
Therapeutic outcome according to histologic subtype in 121 patients with malignant pleural mesotheliomaG L Ceresoli
Department of Radiochemotherapy, San Raffaele H Scientific Institute, Via Olgettina 60, 20132 Milan, Italy
Lung Cancer 34:279-87. 2001..However, these results must be confirmed in a larger prospective trial with uniform treatment...
Automatic registration of PET and CT studies for clinical use in thoracic and abdominal conformal radiotherapyG Rizzo
Institute of Molecular Bioimaging and Physiology IBFM CNR, Milan, Italy
Q J Nucl Med Mol Imaging 49:267-79. 2005....
Feasibility of [18F]FDG-PET and coregistered CT on clinical target volume definition of advanced non-small cell lung cancerC Messa
DNTB, School of Medicine, University of Milano Bicocca, Milan, Italy
Q J Nucl Med Mol Imaging 49:259-66. 2005..To prospectively evaluate the impact of coregistered positron emission tomography (PET) and computed tomography (CT) in 3D conformal radiotherapy (3D-CRT) planning in patients with non-small lung cancer (NSCLC)...
18-FDG positron emission tomography in the evaluation of malignant pleural diseases - a pilot studyA Carretta
Department of Thoracic Surgery, University of Milan, Scientific Institute H San Raffaele, Via Olgettina, 60 20132, Milan, Italy
Eur J Cardiothorac Surg 17:377-83. 2000..The aim of this study was to evaluate the role of 18-FDG PET in the diagnostic assessment of pleural diseases...
Consolidation radiotherapy to bulky or semibulky lesions in the management of stage III-IV diffuse large B cell lymphomasA J Ferreri
Department of Radiochemotherapy, San Raffaele H Scientific Institute, Milan, Italy
Oncology 58:219-26. 2000..To assess the impact on survival of consolidation radiotherapy to bulky or semibulky lesions in patients with advanced diffuse large B cell lymphoma (DLCL) in complete remission after primary chemotherapy...
Diagnostic and therapeutic management of neuroendocrine lung tumors: a clinical study of 44 casesA Carretta
Department of Thoracic Surgery, Scientific Institute H San Raffaele, University of Milan, Via Olgettina, 60 20132, Milan, Italy
Lung Cancer 29:217-25. 2000..The prognostic role of biological factors such as cytometry and genetic markers requires further investigation before any definitive conclusions can be drawn...
Role of cMET expression in non-small-cell lung cancer patients treated with EGFR tyrosine kinase inhibitorsP A Zucali
Department of Medical Oncology and Hematology, Istituto Clinico Humanitas, Rozzano, Milan, Italy
Ann Oncol 19:1605-12. 2008..However, resistance mechanisms are not well understood. We evaluated several potential biological markers of intrinsic EGFR-TKIs-resistance in NSCLC...
Therapeutic management with adriamycin-containing chemotherapy and radiotherapy of monostotic and polyostotic primary non-Hodgkin's lymphoma of bone in adultsA J Ferreri
Department of Radiochemotherapy, San Raffaele H Scientific Institute, Milan, Italy
Cancer Invest 16:554-61. 1998..Patients with multiple adjacent lesions that can be included within a single radiation field with acceptable toxicity should be treated as cases of monostotic PLB...
Effect on local control and survival of electron beam intraoperative irradiation for resectable pancreatic adenocarcinomaM Reni
Department of Radiochemotherapy, San Raffaele H Scientific Institute, Milan, Italy
Int J Radiat Oncol Biol Phys 50:651-8. 2001..To assess the impact on local control and survival of intraoperative radiotherapy (IORT) in resectable pancreatic adenocarcinoma...
Evaluation of radiological and pathological prognostic factors in surgically-treated patients with bronchoalveolar carcinomaA Carretta
Department of Thoracic Surgery, Scientific Institute H San Raffaele, Milan, Italy
Eur J Cardiothorac Surg 20:367-71. 2001..The aim of this study was to retrospectively evaluate radiological and pathological factors affecting survival in patients with bronchoalveolar carcinoma (BAC) or BAC associated with adenocarcinoma who underwent surgical treatment...
Irradiation fields and doses in glioblastoma multiforme: are current standards adequate?M Reni
Department of Radiochemotherapy, San Raffaele Hospital Scientific Institute, Milan, Italy
Tumori 87:85-90. 2001..To better characterize a standard radiotherapy in glioblastoma multiforme, the impact on survival of different fields and doses was analyzed in a retrospective single center series...
Advances in the biology of malignant pleural mesotheliomaP A Zucali
Department of Medical Oncology, Istituto Clinico Humanitas, Via Manzoni 56, 20089 Rozzano, Milan, Italy
Cancer Treat Rev 37:543-58. 2011..This paper reviews advances in the molecular biology of malignant pleural mesothelioma in terms of pathogenesis, the major molecular pathways and the associated therapeutic strategies, and the roles of biomarkers...
Second-line chemotherapy in malignant pleural mesothelioma: Results of a retrospective multicenter surveyP A Zucali
Department of Oncology, Humanitas Cancer Center, Rozzano, Italy
Lung Cancer 75:360-7. 2012..Considering the important limitations of this study, due to retrospective nature and the possible selection bias, prospective clinical trials are warranted to clarify these issues...
Pemetrexed plus carboplatin in elderly patients with malignant pleural mesothelioma: combined analysis of two phase II trialsG L Ceresoli
Department of Oncology, Istituto Clinico Humanitas IRCCS, Rozzano, Milano, Italy
Br J Cancer 99:51-6. 2008..9 months, P=0.12). Apart from slightly worse haematological toxicity, there was no significant difference in outcome or toxicity between age groups. The PC regimen is effective and well tolerated in selected elderly patients with MPM...
Differential diagnosis and management of focal ground-glass opacitiesM Infante
Dept of Thoracic Surgery, IRCCS Istituto Clinico Humanitas, Milan, Italy
Eur Respir J 33:821-7. 2009..The stepwise approach adopted in the present study increased the diagnostic specificity and reduced time to definitive diagnosis. Segmentectomy might be the ideal resection volume for such tumours...
Multi-modal medical image integration to optimize radiotherapy planning in lung cancer treatmentG Rizzo
IBFM CNR, Via Fratelli Cervi 93, Segrate, Milan, Italy
Ann Biomed Eng 32:1399-408. 2004..The proposed method for PET/CT integration has been confirmed as being useful for optimizing radiotherapy planning in lung cancer treatment...
Akt phosphorylation and gefitinib efficacy in patients with advanced non-small-cell lung cancerFederico Cappuzzo
Department of Oncologic Sciences, Bellaria Maggiore Hospital, Bologna, Italy
J Natl Cancer Inst 96:1133-41. 2004....
Significant correlation between rectal DVH and late bleeding in patients treated after radical prostatectomy with conformal or conventional radiotherapy (66.6-70.2 Gy)Cesare Cozzarini
Department of Radiochemotherapy, San Raffaele H Scientific Institute, Milan, Italy
Int J Radiat Oncol Biol Phys 55:688-94. 2003..1; p = 0.001) are independently predictive of late bleeding. CONCLUSIONS: DVHs of the rectum are significantly correlated with late bleeding for patients irradiated at 66.6-70.2 Gy after radical prostatectomy...
Short schedule of cisplatin and vinorelbine: a dose-finding study in non-small-cell lung cancerPaolo Andrea Zucali
Department of Medical Oncology and Hematology, Istituto Clinico Humanitas, Rozzano, Milan, Italy
Oncology 71:229-36. 2006..A dose-finding study of a new cisplatin/vinorelbine schedule was done to increase activity of the combination, and improve compliance of non-small-cell lung cancer PATIENTS...
Phase II trial of alternating intravenous and oral vinorelbine in combination with cisplatin in advanced non-small cell lung cancerElisabetta Campagnoli
Dipartimento di Oncologia Medica e Ematologia, Istituto Clinico Humanitas IRCCS, Via Manzoni 56, 20089, Rozzano, MI, Italy
Invest New Drugs 25:559-64. 2007..Non-haematological toxicity was mild. This schedule of cisplatin and vinorelbine treatment showed a good toxicity profile and an efficacy similar to other standard regimens. Oral vinorelbine could be administered safely at home on day 5...
Role of computed tomography and [18F] fluorodeoxyglucose positron emission tomography image fusion in conformal radiotherapy of non-small cell lung cancer: a comparison with standard techniques with and without elective nodal irradiationGiovanni Luca Ceresoli
Department of Oncology and Hematology, Istituto Clinico Humanitas, Rozzano, Milan, Italy
Tumori 93:88-96. 2007....
Effects of gefitinib on serum epidermal growth factor receptor and HER2 in patients with advanced non-small cell lung cancerVanesa Gregorc
Department of Oncology, Scientific Institute University Hospital San Raffaele, Milan
Clin Cancer Res 10:6006-12. 2004....
Target delineation in post-operative radiotherapy of brain gliomas: interobserver variability and impact of image registration of MR(pre-operative) images on treatment planning CT scansGiovanni Mauro Cattaneo
Medical Physics, Scientific Institute, H S Raffaele, Milano, Italy
Radiother Oncol 75:217-23. 2005..To investigate the interobserver variability of intracranial tumour delineation on computed tomography (CT) scans using pre-operative MR hardcopies (CT+MR(conv)) or CT-MR (pre-operative) registered images (CT+MR(matched))...
Prognostic significance of cancer-testis gene expression in resected non-small cell lung cancer patientsGiulio Melloni
Department of Thoracic Surgery, Scientific Institute H. San Raffaele, Italy
Oncol Rep 12:145-51. 2004..In conclusion, the detection of GAGE gene expression by RT-PCR appears to be an independent survival predictor in completely resected NSCLC patients...
Anatomic variations due to radical prostatectomy. Impact on target volume definition and dose-volume parameters of rectum and bladderGiuseppe Sanguineti
Department of Radiation Oncology, University of Texas Medical Branch, Galveston, Texas 77555 0711, USA
Strahlenther Onkol 180:563-72. 2004..The purpose of this study was to investigate the impact of prostatectomy on the definition of CTV, on the position of bladder and rectum and their implications for three-dimensional conformal radiotherapy (3-D CRT)...
Role of postoperative radiotherapy after pelvic lymphadenectomy and radical retropubic prostatectomy: a single institute experience of 415 patientsCesare Cozzarini
Department of Radiochemotherapy, San Raffaele H Scientific Institute, Milan, Italy
Int J Radiat Oncol Biol Phys 59:674-83. 2004....
Molecular alterations in spontaneous sputum of cancer-free heavy smokers: results from a large screening programEkaterina Baryshnikova
Molecular Genetics Laboratory, IRCCS Istituto Clinico Humanitas, Milan, Italy
Clin Cancer Res 14:1913-9. 2008....
Current state and future directions of pleural mesothelioma imagingSamuel G Armato
Department of Radiology, The University of Chicago, 5841 S Maryland Ave, MC 2026, Chicago, IL 60637, USA
Lung Cancer 59:411-20. 2008..From diagnosis to response, PET/CT to molecular bioprobes, volumetric analysis to computerized tumor assessment, imaging promises to provide valuable insight for patients with mesothelioma and the physicians who treat them...
Multidisciplinary treatment of malignant pleural mesotheliomaGiovanni Luca Ceresoli
Dipartimento di Oncologia Medica e Ematologia, Istituto Clinico Humanitas IRCCS, Via Manzoni, Rozzano MI, Italy
Oncologist 12:850-63. 2007..However, currently available treatments still appear to have modest results. Further studies are needed to provide evidence-based recommendations for the treatment of early and advanced stages of this disease...
Factors predicting radiation pneumonitis in lung cancer patients: a retrospective studyTiziana Rancati
Physics Department, University of Milano, Via Celoria 16, 20133, Milan, Italy
Radiother Oncol 67:275-83. 2003..In the entire population NTCP values were not significantly correlated with the incidence of RP. Mean lung dose shows a clear trend toward statistical significance in the patient group without COPD...
