Research Topics
| Antonino RomanoSummaryCountry: Italy Publications
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Publications
Diagnosis and management of drug hypersensitivity reactionsAntonino Romano
Allergy Unit, Complesso Integrato Columbus, Rome, Italy
J Allergy Clin Immunol 127:S67-73. 2011..Desensitization also permits the use of aspirin in aspirin-sensitive patients undergoing revascularization and in subjects with aspirin-exacerbated respiratory disease...- Patch testing in non-immediate drug eruptionsAntonino Romano
Department of Internal Medicine and Geriatrics, Università Cattolica del Sacro Cuore UCSC Allergy Unit, C, I, Columbus, Rome, Italy, and Istituto di Ricovero e Cura a Carattere Scientifico IRCCS Oasi Maria S, S, Troina, Italy
Allergy Asthma Clin Immunol 4:66-74. 2008..Patch tests can be performed with any form of commercial drugs and are safer than intradermal tests. However, patch tests are less sensitive than intradermal tests, and their sensitivity may vary, depending on the vehicle used... - IgE-mediated hypersensitivity to cephalosporins: cross-reactivity and tolerability of penicillins, monobactams, and carbapenemsAntonino Romano
Allergy Unit, Complesso Integrato Columbus, Rome, Italy
J Allergy Clin Immunol 126:994-9. 2010..There have been few studies regarding the cross-reactivity and tolerability of penicillins, aztreonam, and carbapenems in large samples of subjects with cephalosporin allergy... - Brief communication: tolerability of meropenem in patients with IgE-mediated hypersensitivity to penicillinsAntonino Romano
Universita Cattolica del Sacro Cuore, Complesso Integrato Columbus, Rome, Italy
Ann Intern Med 146:266-9. 2007..Although clinicians avoid giving meropenem to patients with penicillin allergy because of potential cross-reactivity, the rate of cross-reactivity between penicillins and meropenem has not been prospectively determined... - Recent advances in the diagnosis of drug allergyAntonino Romano
Allergy Unit of Integrated Complex Columbus, Catholic University of Sacred Heart, Rome, Italy
Curr Opin Allergy Clin Immunol 7:299-303. 2007..Immediate reactions occur within 1 h; nonimmediate ones occur after more than 1 h... - Diagnosing hypersensitivity reactions to cephalosporins in childrenAntonino Romano
Unità di Allergologia, Complesso Integrato Columbus, Via G Moscati, 31, 00168 Rome, Italy
Pediatrics 122:521-7. 2008..The goals were to evaluate the usefulness of skin tests, patch tests, serum specific IgE assays, and challenges in diagnosing hypersensitivity reactions to cephalosporins and to clarify the pathogenic mechanism of such reactions... - Cross-reactivity and tolerability of cephalosporins in patients with immediate hypersensitivity to penicillinsAntonino Romano
Universita Cattolica del Sacro Cuore, Complesso Integrato Columbus, Rome, Italy
Ann Intern Med 141:16-22. 2004..In patients with documented IgE-mediated hypersensitivity to penicillins, data on sensitization to cephalosporins vary. Administering cephalosporins to such patients is often deferred because of the risk for cross-reactivity... - Etoricoxib tolerability in patients with hypersensitivity to nonsteroidal anti-inflammatory drugsMarinella Viola
Department of Internal Medicine and Geriatrics, UCSC Allergy Unit, Complesso Integrato Columbus, Rome, Italy
Int Arch Allergy Immunol 143:103-8. 2007..Our aim was to investigate the clinical tolerability of etoricoxib, a new selective cyclooxygenase-2 inhibitor, in a group of patients with well-established NSAID hypersensitivity... - Celecoxib tolerability in patients with hypersensitivity (mainly cutaneous reactions) to nonsteroidal anti-inflammatory drugsMarinella Viola
Department of Internal Medicine and Geriatrics, UCSC-Allergy Unit, Complesso Integrato Columbus, Rome, Italy
Int Arch Allergy Immunol 137:145-50. 2005..CONCLUSIONS: Celecoxib showed a 98.9% rate of tolerability in the 92 patients with exclusively cutaneous reactions and was well tolerated by all 28 subjects with NSAID-related respiratory or anaphylactic symptoms... - Hypersensitivity to aromatic anticonvulsants: in vivo and in vitro cross-reactivity studiesAntonino Romano
Department of Internal Medicine and Geriatrics, UCSC Allergy Unit, Complesso Integrato Columbus, Rome, Italy
Curr Pharm Des 12:3373-81. 2006..e., assessed by lymphocyte toxicity assays) is high. Further in vivo and in vitro studies in large samples of subjects are needed to evaluate cross-reactivity among aromatic anticonvulsants... - Cross-reactive reactions to nonsteroidal anti-inflammatory drugsMarinella Viola
Department of Internal Medicine and Geriatrics, UCSC Allergy Unit, Complesso Integrato Columbus, Rome, Italy
Curr Pharm Des 14:2826-32. 2008..Many subjects report cutaneous and/or respiratory symptoms and, less frequently, anaphylactic shock after the administration of one (single-reactors) or different (cross-reactors) drugs of this class... - Cross-reactivity among drugs: clinical problemsAntonino Romano
Department of Internal Medicine and Geriatrics, UCSC Allergy Unit, Unità di Allergologia, Complesso Integrato Columbus, via G Moscati 31, 00168 Rome, Italy
Toxicology 209:169-79. 2005.... - Hypersensitivity to lamotrigine and nonaromatic anticonvulsant drugs: a reviewFrancesco Gaeta
Department of Internal Medicine and Geriatrics, UCSC Allergy Unit, Complesso Integrato Columbus, Rome, Italy
Curr Pharm Des 14:2874-82. 2008..Challenge tests can also be useful to identify safe alternatives. Our study reports hypersensitivity reactions to lamotrigine and to nonaromatic antiepileptic drugs, especially those assessed by allergologic tests... - Immediate hypersensitivity to cephalosporinsAntonino Romano
Department of Internal Medicine and Geriatrics, UCSC-Allergy Unit, Cl Columbus, I-00168 Rome, Italy
Allergy 57:52-7. 2002 - Tolerability of rofecoxib in patients with adverse reactions to nonsteroidal anti-inflammatory drugs: a study of 216 patients and literature reviewMaria Rosaria Perrone
Department of Internal Medicine and Geriatrics, UCSC-Allergy Unit, Complesso Integrato Columbus, Rome, Italy
Int Arch Allergy Immunol 132:82-6. 2003..Rofecoxib also had a very low rate (1.6%) of cross-reactivity in the 600 patients with exclusively cutaneous reactions to NSAIDs... - Effective prophylactic protocol in delayed hypersensitivity to contrast media: report of a case involving lymphocyte transformation studies with different compoundsAntonino Romano
Department of Internal Medicine and Geriatrics, Universita Cattolica del Sacro Cuore, Allergy Unit, Complesso Integrato Columbus, via G Moscati 31, 00168 Rome, Italy
Radiology 225:466-70. 2002..The patient received 6-alpha-methylprednisolone and cyclosporine 1 week before and 2 weeks after four angiograms were obtained with the use of iobitridol, which was well tolerated... - IgE-mediated hypersensitivity to cephalosporinsJean Louis Gueant
INSERM U 724, Laboratoire de Pathologie Cellulaire et Moléculaire en Nutrition and Department of Clinical Biochemistry, University Hospital Center of Nancy and Medical Faculty, University Henry Poincaré, 54500, Nancy, France
Curr Pharm Des 12:3335-45. 2006..In assessing the selectivity of the response, negative results in skin testing with cephalosporins other than the responsible one appear to be a reliable indicator of tolerability... - Update on beta-lactam allergy diagnosisPascal Demoly
Exploration des Allergies, Maladies Respiratoires, INSERM U454 IFR3, Hopital Arnaud de Villeneuve, University Hospital of Montpellier, 34295 Montpellier Cedex 5, France
Curr Allergy Asthma Rep 5:9-14. 2005..In this review, we describe the general guidelines for evaluating subjects in whom there is suspicion of allergic reactions to beta-lactams... - Imipenem in patients with immediate hypersensitivity to penicillinsAntonino Romano
N Engl J Med 354:2835-7. 2006 - Hypersensitivity reactions to complementary and alternative medicine productsMaria Teresa Ventura
Department of Internal Medicine, Immunology and Infectious Diseases MIDIM, University of Bari Medical School, Policlinico, Piazza G Cesare, 11, 70124 Bari, Italy
Curr Pharm Des 12:3393-9. 2006..Because little is known about adverse reactions to CAM products, further systematic studies and an appropriate regulation by heath authorities are necessary... - Hypersensitivity reactions to iodinated contrast mediaRosa Maria Guéant-Rodriguez
INSERM U 724, Laboratory of Cellular and Molecular Pathology in Nutrition, Faculty of Medicine, B P 184 54505 Vandoeuvre les Nancy Cedex, France
Curr Pharm Des 12:3359-72. 2006..This paper summarizes the current state of the art and addresses the research that is still needed on the pathogenic mechanisms, diagnosis, and prevention of ICM-induced hypersensitivity reactions... - Parecoxib tolerability in patients with hypersensitivity to nonsteroidal anti-inflammatory drugsMarinella Viola
J Allergy Clin Immunol 117:1189-91. 2006 - Delayed reactions to drugs show levels of perforin, granzyme B, and Fas-L to be related to disease severitySinforiano J Posadas
Allergy Service, La Paz Hospital, Madrid; the Research Unit for Allergy Diseases, Carlos Haya Hospital, Malaga, Spain
J Allergy Clin Immunol 109:155-61. 2002..These findings support the role of T cells in allergic drug reactions and provide further clues pertaining to therapeutic interventions...