Research Topics
| V OjettiSummaryCountry: Italy Publications
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Publications
The metabolic and toxicological considerations for mTOR inhibitors in the treatment of hepatocarcinomaFrancesca Ponziani
Catholic University of Sacred Heart, Gemelli Hospital, Largo A Gemelli, 8 Rome 00168, Italy
Expert Opin Drug Metab Toxicol 7:1535-46. 2011..Moreover, the authors believe that mTOR inhibitors could be used in a combined pharmacological approach to improve HCC molecular-targeted therapy by producing a multiple-level block of tumor intracellular signaling...
The effect of oral supplementation with Lactobacillus reuteri or tilactase in lactose intolerant patients: randomized trialV Ojetti
Department of Internal Medicine, Catholic University of the Sacred Heart, Rome, Italy
Eur Rev Med Pharmacol Sci 14:163-70. 2010....
Small bowel bacterial overgrowth and type 1 diabetesV Ojetti
Department of Internal Medicine, Catholic University of the Sacred Heart, Rome, Italy
Eur Rev Med Pharmacol Sci 13:419-23. 2009..Impaired intestinal motility is often associated with small-bowel bacterial overgrowth (SIBO) but only few studies evaluated the relationship between autonomic neuropathy and SIBO in diabetic pts...
The role of H. pylori infection in diabetesVeronica Ojetti
Department of Internal Medicine, Catholic University, Gemelli Hospital, Largo Gemelli, 8, 00168, Rome, Italy
Curr Diabetes Rev 1:343-7. 2005..Reduced lymphocyte activity, neutrophil dysfunction with failure of chemotaxis and a possible reservoir of H. pylori in dental plaque may explain the higher rate of re-infection in these patients...
A case-control study comparing methylene blue directed biopsies and random biopsies for detecting pre-cancerous lesions in the follow-up of gastric cancer patientsV Ojetti
Department of Surgery, Catholic University, Rome, Italy
Eur Rev Med Pharmacol Sci 11:291-6. 2007..To compare the accuracy of Methylene Blue (MB) targeted biopsies with random biopsies in detecting intestinal metaplasia and dysplasia in the follow-up of patients after gastrectomy for gastric cancer...
Quick test: a new test for the diagnosis of duodenal hypolactasiaVeronica Ojetti
Department of Internal Medicine, Gemelli Hospital, Catholic University, Largo Gemelli 8, 00168 Rome, Italy
Dig Dis Sci 53:1589-92. 2008..Based on these results we suggest performing the less expensive and more rapid QLT during the upper gastrointestinal endoscopy to evaluate the presence of lactase activity in duodenal biopsies...
Regression of lactose malabsorption in coeliac patients after receiving a gluten-free dietVeronica Ojetti
Internal Medicine Catholic University, Rome, Italy
Scand J Gastroenterol 43:174-7. 2008..Our aim was to evaluate the effect of a gluten-free diet on lactose malabsorption assessed using the hydrogen lactose breath test (LBT) and also the relationship with normalization of duodenal biopsies in coeliac patients...
Malabsorption in psoriatic patients: cause or consequence?Veronica Ojetti
Department of Internal Medicine, Catholic University, Rome, Italy
Scand J Gastroenterol 41:1267-71. 2006..Small-bowel abnormalities can cause clinical or, more frequently, laboratory alterations that give rise to malabsorption. The aim of the study was to evaluate the prevalence of malabsorption in psoriatic patients...
Association between Helicobacter pylori cytotoxic type I CagA-positive strains and migraine with auraA Gasbarrini
Angiology Department, Catholic University, Rome, Italy
Cephalalgia 20:561-5. 2000..A higher inflammatory response of the gastric mucosa to more virulent strains could release substances that may act as triggers of vasospasm in peculiar cerebral arterial districts, probably implicated in the 'aura' phenomenon...
The effect of oral administration of Lactobacillus GG on antibiotic-associated gastrointestinal side-effects during Helicobacter pylori eradication therapyA Armuzzi
Department of Internal Medicine, Catholic University, Rome, Italy
Aliment Pharmacol Ther 15:163-9. 2001..04). CONCLUSIONS: Lactobacillus GG supplementation showed a positive impact on H. pylori therapy-related side-effects and on overall treatment tolerability...
Moxifloxacin-based strategies for first-line treatment of Helicobacter pylori infectionE C Nista
Department of Internal Medicine, Catholic University, Rome, Italy
Aliment Pharmacol Ther 21:1241-7. 2005..CONCLUSIONS: Seven-day moxifloxacin-based triple therapies provide optimal eradication rates with a good compliance when compared with the standard triple therapy schemes...
Helicobacter pylori CagA-positive strains affect oxygen free radicals generation by gastric mucosaS Danese
Dept. of Clinical Chemistry, Gemelli Hospital, Catholic University, Rome, Italy
Scand J Gastroenterol 36:247-50. 2001..Assessment of CagA status might be useful to discriminate patients in which H. pylori eradication is advisable...
Prevalence of and risk factors for Helicobacter pylori infection among healthcare workers at a teaching hospital in Rome: the Catholic University Epidemiological StudyA Gasbarrini
Department of Medical Pathology, Gemelli Hospital, Catholic University, Rome, Italy
Eur J Gastroenterol Hepatol 13:185-9. 2001..To evaluate the prevalence of and the risk factors for Helicobacter pylori in a population of medical and non-medical workers at a teaching hospital in Rome, Italy...
Beta-lactamase inhibitor enhances Helicobacter pylori eradication rateV Ojetti
Departments of Internal Medicine and Gastroenterology, Gemelli Teaching Hospital, Catholic University of Rome, Rome, Italy
J Intern Med 255:125-9. 2004..pylori eradication rate than amoxicillin alone, without any increase in side-effects. The combination of amoxicillin and clavulanate may represent an alternative therapeutic scheme for the treatment of H. pylori infection...
Efficacy of Lactobacillus GG in maintaining remission of ulcerative colitisM A Zocco
Department of Internal Medicine, Catholic University of Rome, Rome, Italy
Aliment Pharmacol Ther 23:1567-74. 2006..05). CONCLUSIONS: Lactobacillus GG seems to be effective and safe for maintaining remission in patients with ulcerative colitis, and it could represent a good therapeutic option for preventing relapse in this group of patients...
Levofloxacin-based triple therapy vs. quadruple therapy in second-line Helicobacter pylori treatment: a randomized trialE C Nista
Internal Medicine Department, Catholic University, Rome, Italy
Aliment Pharmacol Ther 18:627-33. 2003..Side-effects were significantly lower in the LAR and LTR groups than in the 14TMBR group. CONCLUSION: Ten-day levofloxacin-based therapies are better than standard quadruple regimens as second-line option for H. pylori eradication...
Efficacy and tolerability of antibiotics in patients undergoing H. pylori eradicationS Danese
Internal Medicine Department, Gemelli Hospital, Catholic University, Rome, Italy
Hepatogastroenterology 48:465-7. 2001..Quadruple therapy, which appear highly efficacious as a second line therapy, is associated with a significantly higher incidence of side effects when compared to first-line treatment...
[Role of Helicobacter pylori infection in insulin-dependent diabetes mellitus]V Ojetti
Policlinico Gemelli, Rome, Italy
Minerva Med 92:137-44. 2001..pylori re-infection was observed in IDDM patients when compared to not IDDM controls. The data suggest that vaccine development seems to be the only effective long run treatment for this subset of patients...
Helicobacter pylori infection affects eosinophilic cationic protein in the gastric juice of patients with idiopathic chronic urticariaV Ojetti
Department of Internal Medicine, Catholic University, Rome, Italy
Int Arch Allergy Immunol 125:66-72. 2001..CONCLUSIONS: Although H. pylori infection affects gastric juice ECP and eosinophil infiltration of ICU patients, the role of the bacterium in the pathogenesis of this skin disorder still remains uncertain...
Antibiotic therapy in small intestinal bacterial overgrowth: rifaximin versus metronidazoleE C Lauritano
Internal Medicine Department, Catholic University of the Sacred Heart, Rome, Italy
Eur Rev Med Pharmacol Sci 13:111-6. 2009..Aim of the study was to assess efficacy, safety and tolerability of rifaximin with respect to metronidazole for the treatment of small intestinal bacterial overgrowth...
High prevalence of celiac disease in patients with lactose intoleranceVeronica Ojetti
Internal Medicine, Catholic University, Rome, Italy
Digestion 71:106-10. 2005..In these subjects lactase deficiency seems to be the only manifestation of celiac disease. We suggest serologic screening for celiac disease in all patients with a positive H2-lactose breath test before beginning a milk-exclusion diet...
Antibodies to Saccharomyces cerevisiae: are they useful in clinical practice?M Candelli
Department of Internal Medicine, Catholic University of Sacred Heart, Rome, Italy
Hepatogastroenterology 50:718-20. 2003..CONCLUSIONS: Our data show an association between Crohn's disease and antibodies to Saccharomyces cerevisiae. However, it does not seem useful in discriminating between ulcerative colitis and colic Crohn's disease...
Helicobacter pylori infection and diabetesV Ojetti
Department of Internal Medicine, Catholic University, Rome, Italy
Minerva Med 101:115-9. 2010..pylori strain selection. Finally, a higher H. pylori re-infection rate in DM patients than in general population has been shown...
Mono, dual and triple moxifloxacin-based therapies for Helicobacter pylori eradicationS Di Caro
Internal Medicine Department, Gemelli Hospital, Rome, Italy
Aliment Pharmacol Ther 16:527-32. 2002..CONCLUSIONS: Mono and dual moxifloxacin-based therapies are not acceptable for H. pylori eradication; conversely, moxifloxacin-based triple therapy may be considered as a new, effective, first-line therapy option...
Levofloxacin-based triple therapy in first-line treatment for Helicobacter pylori eradicationEnrico C Nista
Department of Internal Medicine, Catholic University, Rome, Italy
Am J Gastroenterol 101:1985-90. 2006..pylori eradication rates than standard regimens. These data suggest levofloxacin-based regimens can be the most effective in first-line anti-H. pylori therapy, at least in the Italian population...
Direct visualization of intestinal villi by high-resolution magnifying upper endoscopy: a validation studyGiovanni Cammarota
Department of Internal Medicine, Institute of Pathology, Catholic University of Medicine and Surgery, Rome, Italy
Gastrointest Endosc 60:732-8. 2004..CONCLUSIONS: High-resolution magnifying upper endoscopy can reliably predict the presence or the absence of duodenal villi...
Real time endoscopic imaging of oxyradical generation in pig stomach during ischemia-reperfusionV Ojetti
Department of Internal Medicine, Catholic University, Rome, Italy
Dig Liver Dis 35:309-13. 2003..This new endoscopic technique could be useful for the assessment of oxidative gastric mucosal injury in several gastric diseases; however, further studies remain necessary to determine the applicability of this technique in humans...
Increased blood pressure variability in menopauseA Migneco
Department of Internal Medicine, Catholic University, Rome, Italy
Eur Rev Med Pharmacol Sci 12:89-95. 2008..Menopausal status, aging and BMI increase may all, independently, contribute to the enhanced blood pressure variability we found in menopausal women...
The water immersion technique is easy to learn for routine use during EGD for duodenal villous evaluation: a single-center 2-year experienceGiovanni Cammarota
Department of Internal Medicine, Endoscopy Unit, A Gemelli University Hospital, Rome, Italy
J Clin Gastroenterol 43:244-8. 2009..We investigated the learning parameters of the immersion technique for the assessment of marked villous atrophy (MVA), during routine esophagogastroduodenoscopy (EGD)...
Eradication of Helicobacter pylori infection improves blood pressure values in patients affected by hypertensionAlessio Migneco
Department of Medical Pathology, Catholic University, Rome, Italy
Helicobacter 8:585-9. 2003..pylori and some peptides expressed by endothelial cells and smooth muscle cells...
Reliability of the "immersion technique" during routine upper endoscopy for detection of abnormalities of duodenal villi in patients with dyspepsiaGiovanni Cammarota
Department of Internal Medicine and Gastroenterology, Institute of Histopathology, Catholic University of Medicine and Surgery, Rome, Italy
Gastrointest Endosc 60:223-8. 2004..This simple diagnostic technique may be performed routinely during endoscopic exploration of duodenum...
Use of amiodarone in emergencyA Testa
Department of Emergency Medicine, Catholic University, Rome, Italy
Eur Rev Med Pharmacol Sci 9:183-90. 2005..Pharmacological interactions are reported with HMG-CoA reductase inhibitors, class I antiarrhythmic agents and other drugs which contribute to prolong QT interval, digoxin, oral anticoagulants and general anaesthesia...
Idiopathic chronic urticaria and celiac diseaseMaurizio Gabrielli
Department of Internal Medicine, Catholic University the Sacred Heart, Rome, Italy
Dig Dis Sci 50:1702-4. 2005..One control of 264 (0.38%) had CD. No statistical difference was found in the prevalence of CD between the two groups. ICU patients do not seem to bear a greater risk for CD compared to the general population...
Management of acute pancreatitis in emergencyV Ojetti
Department of Emergency Medicine, Catholic University, Rome, Italy
Eur Rev Med Pharmacol Sci 9:133-40. 2005..Patients with gallstone pancreatitis should have definitive Endoscopic Retrograde Colangio-Pancreatography (ERCP) or surgical management of the gallstones...
Intestinal permeability in cirrhotic patients with and without spontaneous bacterial peritonitis: is the ring closed?Emidio Scarpellini
Department of Internal Medicine, Catholic University of Sacred Heart, Gemelli Hospital, Rome, Italy
Am J Gastroenterol 105:323-7. 2010..The aim of this study was to assess IP in LC patients with respect to healthy controls...
Acute cryptogenic liver failure in an untreated coeliac patient: a case reportVeronica Ojetti
Departments of Emergency Medicine, Catholic University, Rome, Italy
Eur J Gastroenterol Hepatol 17:1119-21. 2005..Investigation of the patient led to the diagnosis of coeliac disease. A gluten-free diet led to the reversal of the severe liver failure, without the necessity for any surgical or medical treatment...
Rifaximin-based regimens for eradication of Helicobacter pylori: a pilot studyAntonio Gasbarrini
Department of Internal Medicine, Gemelli University Hospital, Catholic University of the Sacred Heart, Rome, Italy
Dig Dis 24:195-200. 2006..Poor compliance and antibiotic resistance are the main causes of treatment failure. The aim of the present study was to assess the efficacy of rifaximin, a poorly absorbed antibiotic, for H. pylori eradication...
Rifaximin pharmacology and clinical implicationsVeronica Ojetti
Internal Medicine Department, Catholic University of Sacred Heart, Gemelli Hospital, Rome, Italy veronica ojetti tin it
Expert Opin Drug Metab Toxicol 5:675-82. 2009..This antibiotic has the advantage of low microbial resistance and few systemic adverse events and is safe in all patient populations, including young children...
Small intestinal bacterial overgrowth: diagnosis and treatmentAntonio Gasbarrini
Internal Medicine Department, Gemelli Hospital, Catholic University of Sacred Heart, Rome, Italy
Dig Dis 25:237-40. 2007..Current SIBO treatment is based on empirical courses of broad-spectrum antibiotics since few controlled studies concerning the choice and duration of antibiotic therapy are available at present...
Lack of endoscopic visualization of intestinal villi with the "immersion technique" in overt atrophic celiac diseaseAntonio Gasbarrini
Internal Medicine and Gastroenterology, Gemelli Teaching Hospital, Catholic University of Rome, Italy
Gastrointest Endosc 57:348-51. 2003..This technique could also be useful for targeting duodenal biopsies...
