Research Topics
| M CostantiniSummaryAffiliation: National Cancer Research Institute Country: Italy Publications
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Detail Information
Publications
The effectiveness of the Liverpool care pathway in improving end of life care for dying cancer patients in hospital. A cluster randomised trialMassimo Costantini
Regional Palliative Care Network, National Cancer Research Institute, Genoa, Italy
BMC Health Serv Res 11:13. 2011..The results from qualitative and quantitative studies suggest that the LCP Program can improve significantly the quality of end-of-life care delivery in hospitals, but no randomised trial has been conducted till now...- Inequity in the provision of and access to palliative care for cancer patients. Results from the Italian survey of the dying of cancer (ISDOC)Monica Beccaro
Unit of Clinical Epidemiology, National Cancer Institute, Genova, Italy
BMC Public Health 7:66. 2007.... - [Improving quality of end-of-life care. A possible and necessary change]Massimo Costantini
SC Coordinamento regionale cure palliative, Istituto Nazionale per la Ricerca sul Cancro, Genova
Epidemiol Prev 35:229-33. 2011..In conclusion, development and assesment of the LCP Program in Italy shows that it is possible to perform studies aimed at assessing complex interventions in end-of-life care... - Health services research on end-of-life careMassimo Costantini
Regional Palliative Care Network, National Cancer Research Institute, Genova, Italy
Curr Opin Support Palliat Care 3:190-4. 2009..To summarize and discuss recent research aimed at evaluating palliative care services, and other complex interventions in end-of-life care... - Prevalence, distress, management, and relief of pain during the last 3 months of cancer patients' life. Results of an Italian mortality follow-back surveyM Costantini
Regional Palliative Care Network, National Cancer Research Institute, Genova, Italy
Ann Oncol 20:729-35. 2009..This study estimates prevalence, management, and relief of pain during the last 3 months of life of a representative sample of dying cancer patients in Italy... - Cancer trajectories at the end of life: is there an effect of age and gender?Massimo Costantini
Regional Palliative Care Network, National Cancer Research Institute, Largo R, Benzi, 10 16132 Genova, Italy
BMC Cancer 8:127. 2008..Few empirical data show the pattern of functional decline at the end of life for cancer patients, especially among older patients... - The last three months of life of Italian cancer patients. Methods, sample characteristics and response rate of the Italian Survey of the Dying of Cancer (ISDOC)Massimo Costantini
Unit of Clinical Epidemiology, National Cancer Institute, Genova, Italy
Palliat Med 19:628-38. 2005..The Italian Survey of the Dying of Cancer (ISDOC) was undertaken to evaluate the experiences of Italian people dying from cancer during their last three months of life in all settings of care... - Interobserver agreement in the histologic diagnosis of colorectal polyps. the experience of the multicenter adenoma colorectal study (SMAC)Massimo Costantini
Unit of Clinical Epidemiology and Trials, National Cancer Institute, Largo Rosanna Benzi 10, Genoa 16132, Italy
J Clin Epidemiol 56:209-14. 2003..84). Agreement on diagnosis of adenoma histologic subtypes, degrees of dysplasia, or infiltrating carcinoma in adenoma was moderate. A simpler classifications might help to better identify patients at different risk of colorectal cancer... - Methodological issues in a before-after study design to evaluate the Liverpool Care Pathway for the Dying Patient in hospitalMassimo Costantini
Regional Palliative Care Network, National Cancer Research Institute, Genoa, Italy
Palliat Med 25:766-73. 2011..The primary aim was to evaluate the feasibility of LCP implementation in the Italian context. The secondary aim of the study was to evaluate the effectiveness of the LCP with an uncontrolled before-after design... - Assessment of DNA flow cytometry as a surrogate end point biomarker in a bladder cancer chemoprevention trialS Bruno
Cytometry Unit, National Cancer Institute, 16132 Genoa, Italy
J Cell Biochem 76:311-21. 1999..We conclude that DNA flow cytometry and conventional cytology on epithelial cells obtained from bladder washings do not appear to provide suitable surrogate endpoint biomarkers during the early stages of bladder carcinogenesis... - Cancer patients as 'experts' in defining quality of life domains. A multicentre survey by the Italian Group for the Evaluation of Outcomes in Oncology (IGEO)M Costantini
Unit of Clinical Epidemiology and Trials, National Cancer Institute, Genoa
Qual Life Res 9:151-9. 2000..These results reinforce the criticism that available quality of life instruments are more likely to reflect the perspective of health professionals than patients... - Detecting psychological distress in cancer patients: validity of the Italian version of the Hospital Anxiety and Depression ScaleM Costantini
Unit of Clinical Epidemiology and Trials, National Cancer Institute, Genoa, Italy
Support Care Cancer 7:121-7. 1999..The use of the two subscales as a 'case identifier' or as an outcome measure should be considered with caution... - Diagnosis and prognosis disclosure among cancer patients. Results from an Italian mortality follow-back surveyM Costantini
Unit of Clinical Epidemiology, National Cancer Institute, Genova, Italy
Ann Oncol 17:853-9. 2006..CONCLUSIONS: These findings suggest that not necessarily the observed cultural changes towards a less paternalistic approach in medical care translate into an effective change in the quantity of information delivered to the patients... - Randomized phase III trial evaluating the role of erythropoietin in the prevention of chemotherapy-induced anemiaL Del Mastro
Divisione di Oncologia Medica I, Istituto Nazionale per la Ricerca sul Cancro, Genova, Italy
J Clin Oncol 15:2715-21. 1997..The aim of this study was to evaluate the ability of EPO in preventing the development of clinically significant anemia in patients treated with chemotherapy... - Predicting mood disorders in breast cancer patientsG Morasso
Department of Psychology, National Cancer Institute, L go R Benzi, 10, 16132, Genova, Italy
Eur J Cancer 37:216-23. 2001.... - Actual and preferred place of death of cancer patients. Results from the Italian survey of the dying of cancer (ISDOC)Monica Beccaro
Unit of Clinical Epidemiology, National Cancer Institute, Largo Rosanna Benzi, 10, 16132, Genoa, Italy
J Epidemiol Community Health 60:412-6. 2006..As home was the preferred place of death for most cancer patients, effective programmes to enable the patients to remain at home should be implemented... - End-of-life care in Italian hospitals: quality of and satisfaction with care from the caregivers' point of view--results from the Italian Survey of the Dying of CancerMonica Beccaro
Regional Palliative Care Network, National Cancer Research Institute, 16132 Genoa, Italy
J Pain Symptom Manage 39:1003-15. 2010..A number of studies have highlighted the poor quality of end-of-life (EOL) care provided in hospital settings, leading to a reduction in the quality of EOL care and increase in patient and caregiver dissatisfaction levels... - An unconventional cancer treatment lacking clinical efficacy remains available to Italian cancer patientsDomenico Franco Merlo
Epidemiology and Biostatistics and Clinical Trials and Bioethics, National Cancer Research Institute, Genoa, Italy
Tumori 94:830-2. 2008..Access to the multitherapy was investigated three years later within the post-bereavement Italian Survey of the Dying of Cancer (ISDOC), whose broader aim was to investigate the end-of-life care experiences of terminal cancer patients... - End-of-life care in Italy: personal experience of family caregivers. A content analysis of open questions from the Italian Survey of the Dying of Cancer (ISDOC)Gabriella Morasso
Unit of Psycho Oncology, National Cancer Institute, Genoa, Italy
Psychooncology 17:1073-80. 2008.... - [Evaluation of quality of life in oncology. Rationale and objectives of the first phase of the Quality of Life in Oncology project]M Costantini
Servizio di Epidemiologia Clinica e Sperimentazioni Controllate, Istituto Nazionale per la Ricerca sul Cancro, Genova, Italy
Tumori 83:S25-7. 1997..The present study shows the possibility to define the content domain of quality of life attributes for cancer patients, using patients as experts... - Effect of a palliative home care team on hospital admissions among patients with advanced cancerMassimo Costantini
Unit of Clinical Epidemiology and Trials, National Cancer Institute, Genova, Italy
Palliat Med 17:315-21. 2003..We conclude that a PHCT appears to reduce days in hospital and allows patients to spend more time at home. Differences in time in care between groups requires further investigations... - Prevalence of pain in Italian hospitals: results of a regional cross-sectional surveyMassimo Costantini
Unit of Clinical Epidemiology and Trials, Biomedical Technology Assessment (Beta, Genoa, Italy
J Pain Symptom Manage 23:221-30. 2002..In a multivariable ordinal regression logistic analysis, only sex, diagnosis, days from surgery, and hospitals remain significantly associated with increased pain prevalence... - Impact of two different dose-intensity chemotherapy regimens on psychological distress in early breast cancer patientsL Del Mastro
Department of Medical Oncology, National Cancer Research Institute, Genova, Italy
Eur J Cancer 38:359-66. 2002..Final results of the randomised trial will indicate whether such higher adverse effects of the dose-intensive regimen are counterbalanced by a higher efficacy of the experimental treatment in terms of survival... - Reliability of short-term esophageal pH monitoring versus 24-hour studyA Barabino
Department of Pediatrics, G Gaslini Institute, Genoa, Italy
J Pediatr Gastroenterol Nutr 21:87-90. 1995..Reflux/h values were not in agreement for the same groups. Absence of agreement was found if the absolute value of RI was considered.(ABSTRACT TRUNCATED AT 250 WORDS).. - Randomized trial of fenretinide in superficial bladder cancer using DNA flow cytometry as an intermediate end pointA Decensi
Division of Medical Oncology II, National Cancer Institute, Genoa, Italy
Cancer Epidemiol Biomarkers Prev 9:1071-8. 2000..Because our data are hampered by the lack of predictivity of the selected biomarkers, additional studies are necessary to assess the activity of fenretinide in preventing bladder cancer... - Dying of cancer in Italy: impact on family and caregiver. The Italian Survey of Dying of CancerPaolo Giorgi Rossi
Agency for Public Health, Lazio Region, via di S Costanza 53, 00198 Rome, Italy
J Epidemiol Community Health 61:547-54. 2007..To describe the effect of terminal cancer on the patient's family, finances and daily life... - Communication in end-of-life cancer care: a comparison of team assessments in three European countriesIrene J Higginson
Department of Palliative Care and Policy, King s College London, Weston Education Centre, London, United Kingdom
J Clin Oncol 20:3674-82. 2002..To compare team assessments of end-of-life communication in three European countries, and to identify factors associated with problematic communication... - The methane sink associated to soils of natural and agricultural ecosystems in ItalySimona Castaldi
Department of Environmental Sciences, Second University of Naples, Via Vivaldi 43, 81100 Caserta, Italy
Chemosphere 66:723-9. 2007..The aggregated CH4 sink, calculated for natural ecosystems present in the Italian region, is significantly higher than previously reported estimates, which were extrapolated from fluxes measured in other temperate ecosystems... - Predicting survival in terminal cancer patients: clinical observation or quality-of-life evaluation?Pietro Toscani
Istituto de Ricerca in Medicina Palliativa L Maestroni, Cremona
Palliat Med 19:220-7. 2005..This study compares the relative prognostic power of clinical variables and quality-of-life (QoL) measures in a population of terminal cancer patients... - [Survival and quality of life: integrated endpoints]Massimo Costantini
Servizio di Epidemiologia Clinica e Sperimentazioni Controllate, Istituto Nazionale per la Ricerca sul Cancro, Genova
Suppl Tumori 3:S10-1. 2004 - Paroxetine in the treatment of severe non-dermatological pruritus: a randomized, controlled trialZbigniew Zylicz
Hospice Rozenheuvel, Rozendaal, The Netherlands
J Pain Symptom Manage 26:1105-12. 2003..The outcome of this study indicates that paroxetine is effective in the treatment of severe pruritus of non-dermatological origin... - [Testing an instrument measuring Italian nurses' knowledge and attitudes regarding pain]Gianluca Catania
Infermiere di Ricerca, S.S. Clinical Trials, IST, Genova
Assist Inferm Ric 25:149-56. 2006....