Research Topics
Species | Jeffrey M HausdorffSummaryAffiliation: Laboratory for Gait and Neurodynamics Country: Italy Publications
| Collaborators
|
Detail Information
Publications
Gait dynamics, fractals and falls: finding meaning in the stride-to-stride fluctuations of human walkingJeffrey M Hausdorff
Laboratory for Gait and Neurodynamics, Movement Disorders Unit, Department of Neurology, Tel Aviv Sourasky Medical Center, Israel
Hum Mov Sci 26:555-89. 2007....
Dual-tasking effects on gait variability: the role of aging, falls, and executive functionShmuel Springer
Movement Disorders Unit, Neurology Department, Tel-Aviv Sourasky Medical Center, Tel-Aviv, Israel
Mov Disord 21:950-7. 2006..In contrast, dual tasking destabilizes the gait of idiopathic elderly fallers, an effect that appears to be mediated in part by a decline in EF...
A training program to improve gait while dual tasking in patients with Parkinson's disease: a pilot studyGalit Yogev-Seligmann
Movement Disorders Unit, Department of Neurology, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel
Arch Phys Med Rehabil 93:176-81. 2012..The present results are also consistent with the possibility that DT gait training enhances divided attention abilities during walking...
Dual tasking, gait rhythmicity, and Parkinson's disease: which aspects of gait are attention demanding?Galit Yogev
Movement Disorders Unit, Neurology Department, Tel-Aviv Sourasky Medical Center, 6 Weizman Street, Tel-Aviv 64239, Israel
Eur J Neurosci 22:1248-56. 2005..Moreover, the associations between executive function and gait variability suggest that a decline in executive function in PD may exacerbate the effects of dual tasking on gait, potentially increasing fall risk...
Gait in attention deficit hyperactivity disorder : effects of methylphenidate and dual taskingYael Leitner
Paediatric Neurology Unit and Child Development Center, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel
J Neurol 254:1330-8. 2007..Cognitive function and the loading of attention presumably play an important role in gait as well as in fall risk, but previous work has not demonstrated this in any cause-and-effect way...
A novel multidomain computerized cognitive assessment for attention-deficit hyperactivity disorder: evidence for widespread and circumscribed cognitive deficitsYael Leitner
Paediatric Neurology Unit and Child Development Center, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel
J Child Neurol 22:264-76. 2007..Hence, on the limited basis of this pilot study, the set of computerized tests studied appears to be useful for measuring cognitive function in ADHD; however, additional studies are needed to confirm this...
Effects of methylphenidate on cognitive function and gait in patients with Parkinson's disease: a pilot studyEitan Auriel
Movement Disorders Unit, NPF Center of Excellence, Department of Neurology, Tel-Aviv Sourasky Medical Center, Tel-Aviv, Israel
Clin Neuropharmacol 29:15-7. 2006..These findings suggest a new potential pharmacologic means of enhancing mobility and decreasing fall risk in Parkinson's disease...
Virtual reality for gait training: can it induce motor learning to enhance complex walking and reduce fall risk in patients with Parkinson's disease?Anat Mirelman
Movement Disorders Unit, Department of Neurology, Tel Aviv Sourasky Medical Center, Israel
J Gerontol A Biol Sci Med Sci 66:234-40. 2011..We hypothesized that VR may be applied to address the multifaceted deficits associated with fall risk in PD...
Effects of cognitive function on gait and dual tasking abilities in patients with Parkinson's disease suffering from motor response fluctuationsMeir Plotnik
Movement Disorders Unit, Department of Neurology, Laboratory for Gait and Neurodynamcis, Tel Aviv Sourasky Medical Center, 6 Weizmann St, Tel Aviv 64239, Israel
Exp Brain Res 208:169-79. 2011....
A common cognitive profile in elderly fallers and in patients with Parkinson's disease: the prominence of impaired executive function and attentionJeffrey M Hausdorff
Movement Disorders Unit, Tel Aviv Sourasky Medical Center
Exp Aging Res 32:411-29. 2006..e., variability of response timing) and underscore the importance of executive function and attention as potential targets for fall risk screening and interventions...
Can methylphenidate reduce fall risk in community-living older adults? A double-blind, single-dose cross-over studyRon Ben-Itzhak
Movement Disorders Unit, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel
J Am Geriatr Soc 56:695-700. 2008..To test the hypothesis that methylphenidate modifies markers of fall risk in older adults...
Executive control deficits as a prodrome to falls in healthy older adults: a prospective study linking thinking, walking, and fallingTalia Herman
Movement Disorders Unit, Department of Neurology, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel
J Gerontol A Biol Sci Med Sci 65:1086-92. 2010..Indeed, the effects of dual tasking (DT) on gait, a challenge to executive control, are more exaggerated in persons with a history of falls. Prospective evidence is, however, lacking...
Dual-task decrements in gait: contributing factors among healthy older adultsJeffrey M Hausdorff
Tel Aviv Sourasky Medical Center, Tel Aviv 64239, Israel
J Gerontol A Biol Sci Med Sci 63:1335-43. 2008..We hypothesized that cognitive and motor reserve (e.g., executive function [EF], postural control, and walking abilities) and affect (e.g., anxiety, depressive symptoms) influence the DT decrements (DTDs) in gait...
Gait asymmetry in patients with Parkinson's disease and elderly fallers: when does the bilateral coordination of gait require attention?Galit Yogev
Movement Disorders Unit, Neurology Department, Tel Aviv Sourasky Medical Center, 6 Weizman Street, Tel Aviv 64239, Israel
Exp Brain Res 177:336-46. 2007..In contrast, however, when gait becomes impaired and less automatic, GA apparently relies on cognitive input and attention...
Can an accelerometer enhance the utility of the Timed Up & Go Test when evaluating patients with Parkinson's disease?Aner Weiss
Laboratory for Gait and Neurodynamics, Movement Disorders Unit, Department of Neurology, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel
Med Eng Phys 32:119-25. 2010..We tested the hypothesis that body-fixed accelerometers can provide insight into TUG performance in PD patients...
Properties of the 'timed up and go' test: more than meets the eyeTalia Herman
Laboratory for Gait Analysis and Neurodynamics, Movement Disorders Unit, Department of Neurology, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel
Gerontology 57:203-10. 2011..We speculated that its properties may be different from other performance-based tests and assessed whether cognitive function may contribute to the differences among these tests in a cohort of healthy older adults...
Bilateral coordination of walking and freezing of gait in Parkinson's diseaseMeir Plotnik
Movement Disorders Unit, Laboratory for Gait and Neurodynamics, Department of Neurology, Tel Aviv Sourasky Medical Center, Israel
Eur J Neurosci 27:1999-2006. 2008..Poor bilateral coordination of walking may predispose to FOG, especially during challenging tasks that demand a high degree of left-right coordination...
When does walking alter thinking? Age and task associated findingsJennifer M Srygley
Movement Disorders Unit, Department of Neurology, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel
Brain Res 1253:92-9. 2009..Age-associated declines in EF apparently contribute to the difference in dual tasking abilities during walking between young and older adults...
Self-report of missteps in older adults: a valid proxy of fall risk?Jennifer M Srygley
Movement Disorders Unit, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel
Arch Phys Med Rehabil 90:786-92. 2009..To evaluate the relationship between missteps and falls and to identify factors associated with missteps, potentially to generate a broader picture of fall risk...
Heart rate changes during freezing of gait in patients with Parkinson's diseaseInbal Maidan
Movement Disorders Unit, Department of Neurology, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel
Mov Disord 25:2346-54. 2010..Although further studies are needed to evaluate these associations, the current results provide experimental evidence linking impaired motor blockades to autonomic nervous system function among patients with PD...
Rhythmic auditory stimulation modulates gait variability in Parkinson's diseaseJeffrey M Hausdorff
Laboratory for Gait and Neurodynamics, Movement Disorders Unit and Parkinson Center, Department of Neurology, Tel Aviv Sourasky Medical Center, 6 Weizman Street, Tel Aviv 64239, Israel
Eur J Neurosci 26:2369-75. 2007....
Assessing fear of falling: Can a short version of the Activities-specific Balance Confidence scale be useful?Chava Peretz
Movement Disorders Unit and Parkinson Center, Department of Neurology, Tel Aviv Sourasky Medical Center, Tel Aviv University, Tel Aviv, Israel
Mov Disord 21:2101-5. 2006..ICCs between the short and the long versions was 0.88 (HLGDs), 0.83 (PDs), and 0.78 (Controls). To conclude, the short version of the ABC has properties analogous to the parent questionnaire and is apparently useful in assessing FOF...
Deep brain stimulation effects on gait variability in Parkinson's diseaseJeffrey M Hausdorff
Tel Aviv Sourasky Medical Center, Israel
Mov Disord 24:1688-92. 2009..These findings suggest that different mechanisms may contribute to performance on UPDRS motor testing and gait stability in response to DBS...
Gait dynamics in Parkinson's disease: common and distinct behavior among stride length, gait variability, and fractal-like scalingJeffrey M Hausdorff
Movement Disorders Unit, Department of Neurology, Tel Aviv Sourasky Medical Center, Tel Aviv 64239, Israel
Chaos 19:026113. 2009....
The Dynamic Gait Index in healthy older adults: the role of stair climbing, fear of falling and genderTalia Herman
Movement Disorders Unit, Department of Neurology, Tel Aviv Sourasky Medical Center, Israel
Gait Posture 29:237-41. 2009..Conversely, ABC scores and fall history were different. These findings suggest that the DGI, although susceptible to ceiling effects, appears to be an appropriate tool for assessing function in healthy older adults...
Is freezing of gait in Parkinson's disease related to asymmetric motor function?Meir Plotnik
Movement Disorders Unit, Department of Neurology, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel
Ann Neurol 57:656-63. 2005..Taken together, the results of this study suggest that bilateral uncoordinated gait and marked gait asymmetry, but not asymmetry in motor performance in general, are associated with FOG...
Marked alterations in the gait timing and rhythmicity of patients with de novo Parkinson's diseaseRossitza Baltadjieva
Laboratory for Gait and Neurodynamics, Movement Disorders Unit and NPF Center for Parkinson's Disease, Department of Neurology, Tel Aviv Sourasky Medical Center, 6 Weizmann Street, Tel Aviv, 64239, Israel
Eur J Neurosci 24:1815-20. 2006..PD apparently impinges on the regulation of a consistent gait rhythm, even early in the course of the disease when observed alterations are not the result of any pharmacologic treatment...
A new measure for quantifying the bilateral coordination of human gait: effects of aging and Parkinson's diseaseMeir Plotnik
Movement Disorders Unit, Tel Aviv Sourasky Medical Center, 6 Weizmann St, Tel Aviv, 64239, Israel
Exp Brain Res 181:561-70. 2007..This study demonstrates that bilateral coordination of gait deteriorates with aging, further deteriorates in PD, and is not strongly associated with other spatio-temporal features of gait...
The role of gait rhythmicity and bilateral coordination of stepping in the pathophysiology of freezing of gait in Parkinson's diseaseMeir Plotnik
Movement Disorders Unit, Department of Neurology, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel
Mov Disord 23:S444-50. 2008....
Gait dynamics in Parkinson's disease: relationship to Parkinsonian features, falls and response to levodopaJoanna D Schaafsma
Movement Disorders Unit, Department of Neurology, Tel Aviv Sourasky Medical Center, and Sackler School of Medicine, Tel Aviv University, 6 Weizmann Street, Tel Aviv 64239, Israel
J Neurol Sci 212:47-53. 2003..Stride-to-stride variability is especially impaired among PD subjects with a history of falls, suggesting, for the first time, the possibility of exaggerated impairment of internal clock function in PD fallers...
The role of executive function and attention in gaitGalit Yogev-Seligmann
Movement Disorders Unit, Department of Neurology, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel
Mov Disord 23:329-42; quiz 472. 2008..Lastly, we suggest how assessments of executive function and attention could be applied in the clinical setting as part of the process of identifying and understanding gait disorders and fall risk...
Audio-biofeedback training for posture and balance in patients with Parkinson's diseaseAnat Mirelman
Laboratory for Gait and Neurodynamics, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel
J Neuroeng Rehabil 8:35. 2011..Based on the observation that postural control improved in patients with vestibular dysfunction after audio-biofeedback training, we tested the feasibility and effects of this training modality in patients with PD...
Six weeks of intensive treadmill training improves gait and quality of life in patients with Parkinson's disease: a pilot studyTalia Herman
Movement Disorders Unit, Tel Aviv Sourasky Medical Center, Department of Physical Therapy, Sackler School of Medicine, Tel Aviv University, Israel
Arch Phys Med Rehabil 88:1154-8. 2007..To evaluate the effects of 6 weeks of intensive treadmill training on gait rhythmicity, functional mobility, and quality of life (QOL) in patients with Parkinson's disease (PD)...
Walking is more like catching than tapping: gait in the elderly as a complex cognitive taskJeffrey M Hausdorff
Movement Disorders Unit, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel
Exp Brain Res 164:541-8. 2005....
Methylphenidate for the treatment of Parkinson disease and other neurological disordersEitan Auriel
Movement Disorders Unit, Department of Neurology, Tel Aviv Sourasky Medical Center, Tel Aviv University, Tel Aviv, Israel
Clin Neuropharmacol 32:75-81. 2009....
Gait alterations in healthy carriers of the LRRK2 G2019S mutationAnat Mirelman
Movement Disorders Unit, Department of NeurologyTel Aviv Sourasky Medical Center, Tel Aviv, Israel
Ann Neurol 69:193-7. 2011..These findings support the possibility of previously unidentified, presymptomatic motor changes among relatives who have an increased risk of developing PD...
Effects of cognitive challenge on gait variability in patients with Parkinson's diseaseJeffrey M Hausdorff
Movement Disorders Unit, Department of Neurology, Tel Aviv Sourasky Medical Center and Sackler School of Medicine, Tel Aviv, Israel
J Geriatr Psychiatry Neurol 16:53-8. 2003..These results highlight the profound effects of attention on gait and indicate that walking while cognitively challenged impairs the ability of patients with PD to maintain a stable walk...
The role of mental function in the pathogenesis of freezing of gait in Parkinson's diseaseNir Giladi
Movement Disorders Unit, NPF Center for Parkinson s Disease, Department of Neurology, Tel Aviv Sourasky Medical Center, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel
J Neurol Sci 248:173-6. 2006..A conceptual model that explains how mental conditions may modulate FOG is developed...
Balance and gait in older adults with systemic hypertensionJeffrey M Hausdorff
Movement Disorders Unit, Department of Neurology, Tel-Aviv Sourasky Medical Center, Sackler School of Medicine, Tel-Aviv University, Tel-Aviv, Israel
Am J Cardiol 91:643-5. 2003
"Brain Screen": A self-referral, screening program for strokes, falls and dementia risk factorsNir Giladi
Movement Disorders Unit, Department of Neurology, Tel Aviv Sourasky Medical Center, 6 Weizman Street, Tel Aviv 64239, Israel
J Neurol 253:307-15. 2006..Falls, strokes and dementia can be predicted and their occurrence can be delayed or even prevented by treatment of risk factors. The value of screening self-referred adults is unknown...
Toward automated, at-home assessment of mobility among patients with Parkinson disease, using a body-worn accelerometerAner Weiss
Laboratory for Gait and Neurodynamics, Movement Disorders Unit, Department of Neurology, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel
Neurorehabil Neural Repair 25:810-8. 2011....
Is freezing of gait in Parkinson's disease a result of multiple gait impairments? Implications for treatmentMeir Plotnik
Laboratory for Gait and Neurodynamics, Movement Disorders Unit, Department of Neurology, Tel Aviv Sourasky Medical Center, Tel Aviv 64239, Israel
Parkinsons Dis 2012:459321. 2012..The proposed theoretical framework sets the stage for testable hypotheses regarding the mechanisms that lead to FOG and may also lead to new treatment ideas...
Automated detection of near falls: algorithm development and preliminary resultsAner Weiss
Laboratory for Gait and Neurodynamics and Movement Disorders Unit, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel
BMC Res Notes 3:62. 2010..The purpose of the present study was to develop a method for automatic detection of near falls, potentially a sensitive, objectivemarker of fall risk and to demonstrate the ability to detect near falls using this approach...
The power of cueing to circumvent dopamine deficits: a review of physical therapy treatment of gait disturbances in Parkinson's diseaseTamar C Rubinstein
Movement Disorders Unit, Neurology Department, Tel-Aviv Sourasky Medical Center, and Sackler School of Medicine, Tel-Aviv University, Tel-Aviv, Israel
Mov Disord 17:1148-60. 2002....
Gait unsteadiness and fall risk in two affective disorders: a preliminary studyJeffrey M Hausdorff
Division on Aging, Harvard Medical School, Boston, MA, USA
BMC Psychiatry 4:39. 2004....
Effects of a new radio frequency-controlled neuroprosthesis on gait symmetry and rhythmicity in patients with chronic hemiparesisJeffrey M Hausdorff
Department of Physical Therapy, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel
Am J Phys Med Rehabil 87:4-13. 2008..To assess the effects of a new neuroprosthesis (NESS L300) designed to ameliorate foot drop on gait symmetry and rhythmicity during walking...
Fractal dynamics in physiology: alterations with disease and agingAry L Goldberger
Cardiovascular Division and Margret and H A Rey Laboratory for Nonlinear Dynamics in Medicine, Department of Medicine, Beth Israel Deaconess Medical Center Harvard Medical School, Boston, MA 02215, USA
Proc Natl Acad Sci U S A 99:2466-72. 2002..Elucidating the fractal and nonlinear mechanisms involved in physiologic control and complex signaling networks is emerging as a major challenge in the postgenomic era...
The role of higher-level cognitive function in gait: executive dysfunction contributes to fall risk in Alzheimer's diseasePamela L Sheridan
Behavioral Neurology Division, Department of Neurology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts 02215, USA
Dement Geriatr Cogn Disord 24:125-37. 2007..We also briefly examine the current treatment of gait instability in AD, mainly exercise, and propose a new approach targeting cognition...
Treadmill walking as an external pacemaker to improve gait rhythm and stability in Parkinson's diseaseSilvi Frenkel-Toledo
Department of Physical Therapy, Sackler School of Medicine, Tel-Aviv, Israel
Mov Disord 20:1109-14. 2005....
Falls and freezing of gait in Parkinson's disease: a review of two interconnected, episodic phenomenaBastiaan R Bloem
Department of Neurology, University Medical Centre St Radboud, Nijmegen, The Netherlands
Mov Disord 19:871-84. 2004....
Influence of executive function on locomotor function: divided attention increases gait variability in Alzheimer's diseasePamela L Sheridan
Department of Neurology, Beth Israel Deaconess Medical Center, Boston, Massachusetts 02215, USA
J Am Geriatr Soc 51:1633-7. 2003..To evaluate how cognitive function and divided attention affect gait in Alzheimer's disease (AD)...
Detecting scaling in the period dynamics of multimodal signals: application to Parkinsonian tremorNir Sapir
Department of Physics and Gonda-Goldschmied Medical Diagnostic Research Center, Bar-Ilan University, Ramat-Gan 52900, Israel
Phys Rev E Stat Nonlin Soft Matter Phys 67:031903. 2003....
Quantifying fractal dynamics of human respiration: age and gender effectsC K Peng
Margret and H. A. Rey Institute for Nonlinear Dynamics in Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA
Ann Biomed Eng 30:683-92. 2002....
Influence of African American elders' age stereotypes on their cardiovascular response to stressBecca R Levy
Department of Epidemiology and Public Health, Yale University, New Haven, CT 06520 8034, USA
Anxiety Stress Coping 21:85-93. 2008..These results suggest that negative age stereotypes generate a susceptibility to stress among African American elders, whereas positive age may provide them with a defense against this stress...
Cognitive function may be important for fall injury prevention trialsJeffrey M Hausdorff
J Am Geriatr Soc 54:865; author reply 865-6. 2006
The sensory feedback mechanisms enabling couples to walk synchronously: an initial investigationAri Z Zivotofsky
Gonda Brain Research Center, Bar Ilan University, Ramat Gan, Israel
J Neuroeng Rehabil 4:28. 2007....
Effects of pharmacological therapy on gait and cognitive function in depressed patientsDiana Paleacu
Neurology Service and Memory Clinic, Abarbanel Mental Health Center, Bat Yam, Israel
Clin Neuropharmacol 30:63-71. 2007..To investigate the relationship among affective status, cognitive function, and gait in depressed patients and to evaluate the effects of treatment of depression on gait and cognitive function...
