Research Topics
| Ettore ZuccatoSummaryAffiliation: Istituto di Ricerche Farmacologiche Mario Negri Country: Italy Publications
| Collaborators
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Detail Information
Publications
Methodological approaches for studying pharmaceuticals in the environment by comparing predicted and measured concentrations in River Po, ItalySara Castiglioni
Department of Environmental Health Sciences, Mario Negri Institute for Pharmacological Research, Via Eritrea 62, 20157 Milan, Italy
Regul Toxicol Pharmacol 39:25-32. 2004..Predictive models might therefore be useful for studying pharmaceuticals in the environment, providing enough experimental data is available on the environmental fate of the molecules...- PCB concentrations in some foods from four European countriesE Zuccato
Food Toxicology Laboratory, Mario Negri Institute for Pharmacological Research, Milan, Italy
Food Chem Toxicol 46:1062-7. 2008..This could have health consequences, because daily intakes are higher than the tolerable levels for a considerable part of the European population... - Illicit drugs, a novel group of environmental contaminantsEttore Zuccato
Department of Environmental Health Sciences, Mario Negri Institute for Pharmacological Research, Via La Masa 19, 20156 Milan, Italy
Water Res 42:961-8. 2008..Since most of these residues still have potent pharmacological activities, their presence in the aquatic environment may have potential implications for human health and wildlife... - Source, occurrence and fate of antibiotics in the Italian aquatic environmentEttore Zuccato
Department of Environmental Health Sciences, Mario Negri Institute for Pharmacological Research, Via La Masa 19, 20156 Milan, Italy
J Hazard Mater 179:1042-8. 2010..In conclusion, antibiotics, particularly macrolides and quinolones, are widespread environmental contaminants, and urban STPs are confirmed a major source of the contamination... - Pharmaceuticals in the environment in Italy: causes, occurrence, effects and controlEttore Zuccato
Department of Environmental Health Sciences, Mario Negri Institute for Pharmacological Research, Via Eritrea 62, 20157 Milan, Italy
Environ Sci Pollut Res Int 13:15-21. 2006..The aim of this work is to review the papers dealing with environmental contamination by pharmaceuticals in Italy, with the aim of providing a comprehensive view on a national scale... - Cocaine in surface waters: a new evidence-based tool to monitor community drug abuseEttore Zuccato
Department of Environmental Health Sciences, Mario Negri Institute for Pharmacological Research, Via Eritrea 62, 20157 Milan, Italy
Environ Health 4:14. 2005..We thus tested a more direct approach based on 'field' evidence of cocaine use by the general population... - Identification of the pharmaceuticals for human use contaminating the Italian aquatic environmentEttore Zuccato
Department of Environmental Health Sciences, Mario Negri Institute for Pharmacological Research, Milan, Italy
J Hazard Mater 122:205-9. 2005.... - Estimating community drug abuse by wastewater analysisEttore Zuccato
Department of Environmental Health Sciences, Istituto di Ricerche Farmacologiche Mario Negri, Milano, Italy
Environ Health Perspect 116:1027-32. 2008..The social and medical problems of drug abuse are a matter of increasing global concern. To tackle drug abuse in changing scenarios, international drug agencies need fresh methods to monitor trends and patterns of illicit drug consumption... - Mass spectrometric analysis of illicit drugs in wastewater and surface waterSara Castiglioni
Department of Environmental Health Sciences, Mario Negri Institute for Pharmacological Research, Via La Masa 19, 20156 Milan, Italy
Mass Spectrom Rev 27:378-94. 2008..Instrumental conditions and fragmentation patterns of illicit drugs and their metabolites are described... - Changes in illicit drug consumption patterns in 2009 detected by wastewater analysisEttore Zuccato
Department of Environmental Health Sciences, Mario Negri Institute for Pharmacological Research, Via G La Masa 19, 20156 Milan, Italy
Drug Alcohol Depend 118:464-9. 2011..Wastewater analysis can provide estimates of illicit drug (ID) consumption in local communities... - Illicit drugs in the environmentEttore Zuccato
Department of Environmental Health Sciences, Mario Negri Institute for Pharmacological Research, Via La Masa 19, 20156 Milan, Italy
Philos Transact A Math Phys Eng Sci 367:3965-78. 2009..Given that current epidemiological methods are indirect and possibly biased, this evidence-based approach offers a new tool for estimating drug abuse in real time... - A multiresidue analytical method using solid-phase extraction and high-pressure liquid chromatography tandem mass spectrometry to measure pharmaceuticals of different therapeutic classes in urban wastewatersSara Castiglioni
Department of Environmental Health Sciences, Mario Negri Institute for Pharmacological Research, Via Eritrea 62, 20157 Milan, Italy
J Chromatogr A 1092:206-15. 2005..The present analytical method was useful to check for pharmaceuticals in various Italian STPs and to identify the most abundant compounds... - The effect of waste combustion on the occurrence of polychlorinated dibenzo-p-dioxins (PCDDs), polychlorinated dibenzofurans (PCDFs) and polychlorinated biphenyls (PCBs) in breast milk in ItalyMaria M Ulaszewska
Mario Negri Institute for Pharmacological Research, Milan, Italy
Chemosphere 82:1-8. 2011..466/2001 and 1881/2006 setting maximum levels for certain contaminants in foodstuffs... - Polychlorobiphenyls (PCBs), polychlorinated dibenzo-p-dioxins (PCDDs) and dibenzofurans (PCDFs) in fruit and vegetables from an industrial area in northern ItalyPaola Grassi
Department of Environmental Health Sciences, Mario Negri Institute for Pharmacological Research, Milan, Italy
Chemosphere 79:292-8. 2010.... - PCDD/Fs and dioxin-like PCBs in human milk and estimation of infants' daily intake: a reviewMaria Malgorzata Ulaszewska
Mario Negri Institute for Pharmacological Research, Department of Environmental Health Science, Via La Masa 19, 20156 Milan, Italy
Chemosphere 83:774-82. 2011.... - Novel homologs of the multiple resistance regulator marA in antibiotic-contaminated environmentsSara Castiglioni
Department of Environmental Health Sciences, Mario Negri Institute for Pharmacological Research, Via La Masa 19, 20156 Milano, Italy
Water Res 42:4271-80. 2008..Quantitative PCR assays indicate that the frequency of this gene in antropised environments seems to be related to bacterial exposure to water-borne antibiotics... - Identification of cocaine and its metabolites in urban wastewater and comparison with the human excretion profile in urineSara Castiglioni
Department of Environmental Health Sciences, Mario Negri Institute for Pharmacological Research, Via La Masa 19, 20156 Milan, Italy
Water Res 45:5141-50. 2011..Results suggested that the measurement of other metabolites in combination with benzoylecgonine might reflect 60% of an administered dose of cocaine providing also information on different patterns of use... - Identification and measurement of illicit drugs and their metabolites in urban wastewater by liquid chromatography-tandem mass spectrometrySara Castiglioni
Department of Environmental Health Sciences, Mario Negri Institute for Pharmacological Research, Via Eritrea 62, 20157 Milan, Italy
Anal Chem 78:8421-9. 2006..As previously reported for cocaine, this method could be useful to estimate and monitor drug consumption in the population in real time, helping social scientists and authorities to combat drug abuse... - Direct analysis of isopropylthioxanthone (ITX) in milk by high-performance liquid chromatography/tandem mass spectrometryRenzo Bagnati
Environmental Health Sciences Department, Istituto di Ricerche Farmacologiche Mario Negri, Via Eritrea 62, 20157 Milano, Italy
Rapid Commun Mass Spectrom 21:1998-2002. 2007..Out of 37 milk samples analyzed, 16 were positive with concentrations ranging from 173-439 microg/L for 2-ITX and from <6 (lower than limit of quantification) to 25 microg/L for 4-ITX... - Removal of pharmaceuticals in sewage treatment plants in ItalySara Castiglioni
Department of Biotechnology and Molecular Sciences, University of Insubria, Via J.H. Dunant 3, 21100 Varese, Italy
Environ Sci Technol 40:357-63. 2006.... - Antibiotics in the environment: occurrence in Italian STPs, fate, and preliminary assessment on algal toxicity of amoxicillinRoberto Andreozzi
Department of Chemical Engineering, University of Naples Federico II, Piazzale Tecchio, 1 80125 Naples, Italy
Environ Sci Technol 38:6832-8. 2004.... - Gene expression profiles in zebrafish (Danio rerio) liver cells exposed to a mixture of pharmaceuticals at environmentally relevant concentrationsFrancesco Pomati
School of Biotechnology and Biomolecular Sciences, The University of New South Wales, Sydney, Australia
Chemosphere 70:65-73. 2007.... - Effects and interactions in an environmentally relevant mixture of pharmaceuticalsFrancesco Pomati
School of Biotechnology and Biomolecular Sciences, The University of New South Wales, Sydney 2052, Australia
Toxicol Sci 102:129-37. 2008..Hazard identification for micropollutants depends heavily on appropriate study designs, and we indicate the use of in vitro cytotoxicity threshold and statistical design of experiments (DOEs) as a valid approach...