Research Topics
| Graziella FilippiniSummaryAffiliation: Istituto Nazionale Neurologico Carlo Besta Country: Italy Publications
| Collaborators
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Detail Information
Publications
Relation of childhood brain tumors to exposure of parents and children to tobacco smoke: the SEARCH international case-control study. Surveillance of Environmental Aspects Related to Cancer in HumansGraziella Filippini
Neuroepidemiology Research Unit, Istituto Nazionale Neurologico C Besta, Milan, Italy
Int J Cancer 100:206-13. 2002..These results did not change considering the child's age at diagnosis, the histologic type of tumor or center...- Interferons in relapsing remitting multiple sclerosis: a systematic reviewGraziella Filippini
Unità di Neuroepidemiologia, Istituto Nazionale Neurologico C Besta, Milan, Italy
Lancet 361:545-52. 2003..Recombinant interferons have been approved by many national regulatory agencies for treatment of relapsing remitting multiple sclerosis, but widespread discussion continues about their true effectiveness, benefits, side-effects, and costs... - Prognostic factors for survival in 676 consecutive patients with newly diagnosed primary glioblastomaGraziella Filippini
Unit of Neuroepidemiology, Fondazione IRCCS Istituto Neurologico Carlo Besta, Via Celoria 11, 20133 Milan, Italy
Neuro Oncol 10:79-87. 2008..The benefit of second surgery at recurrence is uncertain, and new trials are needed to assess its effectiveness. Chemotherapy with PCV or temozolomide seems to be a reasonable option at tumor recurrence... - Treatment of recurrent glioblastoma: can local delivery of mitoxantrone improve survival?Amerigo Boiardi
Department of Neuro Oncology, Fondazione IRCSS Istituto Neurologico Carlo Besta, Via Celoria 11, Milan, Italy
J Neurooncol 88:105-13. 2008..64; 0.46-0.89), but the most significant favorable prognostic factor for survival was the local delivery of mitoxantrone which reduced the risk of death to 50% (HR = 0.50; 0.38-0.68)... - Salvage chemotherapy with procarbazine and fotemustine combination in the treatment of temozolomide treated recurrent glioblastoma patientsAntonio Silvani
Department of Neuro Oncology, Fondazione IRCCS Istituto Neurologico Carlo Besta, Milan, Italy
J Neurooncol 87:143-51. 2008..7-24.8). We concluded that the PCB + FTM combination as done in the current trial for patients with recurrent GBM after treatment with TMZ showed some benefit with regards to increased survival and that a Phase III trial is warranted... - Survival of 793 patients with amyotrophic lateral sclerosis diagnosed over a 28-year periodDaniela Testa
Department of Neurology, Istituto Nazionale Neurologico Carlo Besta, Milan, Italy
Amyotroph Lateral Scler Other Motor Neuron Disord 5:208-12. 2004..We also found a significant increase in survival over time, probably due to improved comprehensive treatment of ALS patients in Italy... - Erythropoietin in amyotrophic lateral sclerosis: a pilot, randomized, double-blind, placebo-controlled study of safety and tolerabilityGiuseppe Lauria
Neuromuscular Diseases Unit, IRCCS Foundation, National Neurological Institute Carlo Besta, Via Celoria 11, Milan, Italy
Amyotroph Lateral Scler 10:410-5. 2009..RhEPO treatment was safe and well tolerated in ALS patients. Our results suggest that larger studies are warranted to confirm safety of treatment and to investigate different dose schedule and efficacy... - Methylation of O6-methylguanine DNA methyltransferase and loss of heterozygosity on 19q and/or 17p are overlapping features of secondary glioblastomas with prolonged survivalMarica Eoli
Unit of Clinical Neuro Oncology, Istituto Nazionale Neurologico Besta, Milan, Italy
Clin Cancer Res 13:2606-13. 2007..Results in contradiction with these findings, however, are present in the literature and the clinical and genetic context framing MGMT methylation is poorly characterized... - Meningiomas invading the superior sagittal sinus: surgical experience in 108 casesFrancesco DiMeco
Department of Neurosurgery, Istituto Nazionale Neurologico C Besta, 20133 Milan, Italy
Neurosurgery 55:1263-72; discussion 1272-4. 2004..There is a lack of published large series to provide definitive guidelines for the surgical treatment of these complex cases. We report our 15-year experience with surgery of parasagittal meningiomas invading the SSS... - Spontaneous intracranial hypotension with deep brain swellingMario Savoiardo
Department of Neuroradiology, Istituto Nazionale Neurologico C Besta, Via Celoria 11, 20133 Milano, Italy
Brain 130:1884-93. 2007..We suggest that in the application of the Monro-Kellie doctrine to SIH, the brain volume should not be considered as always invariable... - Lack of evidence for use of glatiramer acetate in multiple sclerosisLuca M Munari
Azienda Ospedaliera Niguarda Ca' Granda, Milan, Italy
Lancet Neurol 3:641. 2004 - Household water source and the risk of childhood brain tumours: results of the SEARCH International Brain Tumor StudyBeth A Mueller
Public Health Sciences Division, Fred Hutchinson Cancer Research Center, PO Box 19024, Mail Stop M4 C308, Seattle, WA 98109 1024, USA
Int J Epidemiol 33:1209-16. 2004..We examined whether household water source and the presence of nitrates or nitrites in residential water were associated with increased risks of childhood brain tumours (CBT)... - Maternal medication use and the risk of brain tumors in the offspring: the SEARCH international case-control studyAmanda H Cardy
Department of Public Health, University of Aberdeen, Aberdeen AB25 2ZD, Scotland, United Kingdom
Int J Cancer 118:1302-8. 2006..This is the largest case-control study of CBT and maternal medications to date. Our data provide little support for an association between maternal use of medications that may form NOC and subsequent development of CBT in the offspring... - Accuracy of magnetic resonance imaging for the diagnosis of multiple sclerosis: systematic reviewPenny Whiting
MRC Health Services Research Collaboration, Department of Social Medicine, Bristol BS8 2PR
BMJ 332:875-84. 2006..To determine the accuracy of magnetic resonance imaging criteria for the early diagnosis of multiple sclerosis in patients with suspected disease... - Accuracy of death certificates for amyotrophic lateral sclerosis varies significantly from north to south of Italy: implications for mortality studiesPaolo Ragonese
Institute of Neuropsychiatry, University of Palermo, Palermo, Italy
Neuroepidemiology 23:73-7. 2004..CONCLUSIONS: Mortality statistics based on official death records do not accurately reflect interregional mortality for ALS in Italy... - Interferon-beta treatment and the natural history of relapsing-remitting multiple sclerosisMarcus Koch
Ann Neurol 63:125-6; author reply 126-7. 2008 - Amyotrophic lateral sclerosis in Olmsted County, Minnesota, 1925 to 1998Daniela Testa
Neurology 60:1560; author reply 1560-1. 2003 - Clinical presentation and progression of sporadic and familial primary torsion dystonia in ItalyAnna Rita Bentivoglio
Istituto di Neurologia, Universita Cattolica del Sacro Cuore, Rome, Italy
Adv Neurol 94:171-8. 2004