Research Topics
| E BiganzoliSummaryAffiliation: Istituto Nazionale Tumori Country: Italy Publications
| Collaborators
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Detail Information
Publications
Recurrence dynamics does not depend on the recurrence siteRomano Demicheli
Department of Medical Oncology, Fondazione Istituto di Ricovero e Cura a Carattere Scientifico Istituto Nazionale Tumori, Milano, Italy
Breast Cancer Res 10:R83. 2008..A few explanations have been suggested to help interpret this finding, assuming that each peak is generated by clustering of similar recurrences and different peaks result from distinct categories of recurrence...
Recurrence and mortality according to estrogen receptor status for breast cancer patients undergoing conservative surgery. Ipsilateral breast tumour recurrence dynamics provides clues for tumour biology within the residual breastRomano Demicheli
Scientific Direction, Fondazione IRCCS Istituto Nazionale Tumori, Milano, Italy
BMC Cancer 10:656. 2010..The study was designed to determine how tumour hormone receptor status affects the subsequent pattern over time (dynamics) of breast cancer recurrence and death following conservative primary breast cancer resection...
A prediction model for breast cancer recurrence after adjuvant hormone therapyP Boracchi
Istituto di Statistica Medica e Biometria, Universita degli Studi di Milano, Milan, Italy
Int J Biol Markers 23:199-206. 2008....
Prognosis in node-negative primary breast cancer: a neural network analysis of risk profiles using routinely assessed factorsE Biganzoli
Unità di Statistica Medica e Biometria, Istituto Nazionale per lo Studio e la Cura dei Tumori, Milan, Italy
Ann Oncol 14:1484-93. 2003..The present study investigated complex time-dependent effects of routinely assessed factors on the risk of breast cancer recurrence over follow-up time, with a partial logistic artificial neural network (PLANN) model...
Relationship between steroid receptors (as continuous variables) and response to adjuvant treatments in postmenopausal women with node-positive breast cancerD Coradini
U O Determinanti Biomolecolari nella Prognosi e Terapia, Istituto Nazionale per lo Studio e la Cura dei Tumori, Milano, Italy
Int J Biol Markers 14:60-7. 1999..Our results seem to suggest that the use of steroid receptor concentrations on a continuous scale, instead of dichotomous "status", is to be preferred in the choice of adequate therapeutic strategies...
Vascular endothelial growth factor in node-positive breast cancer patients treated with adjuvant tamoxifenD Coradini
Unità Operativa Determinanti Biomolecolari nella Prognosi e Terapia, Istituto Nazionale per lo Studio e la Cura dei Tumori, Via Venezian, 1, 20133 Milan, Italy
Br J Cancer 89:268-70. 2003..These findings indicate that tumour progression, activated or sustained by high VEGF levels, may be counteracted in high-ER(LBA) cancers by tamoxifen, which in contrast fails to contrast the metastatic potential in low-ER(LBA) tumours...
Contribution of vascular endothelial growth factor to the Nottingham prognostic index in node-negative breast cancerD Coradini
, , Milan, Italy
Br J Cancer 85:795-7. 2001..VEGF provided an additional prognostic contribution to NPI mainly within ER-poor tumours...
Prognostic factors for metachronous contralateral breast cancer: a comparison of the linear Cox regression model and its artificial neural network extensionL Mariani
Istituto Nazionale per lo Studio e la Cura dei Tumori, Milan, Italy
Breast Cancer Res Treat 44:167-78. 1997..Research for better prognostic variables should therefore continue...
Time-dependent relevance of steroid receptors in breast cancerD Coradini
Unità Operativa Determinanti Biomolecolari nella Prognosi e Terapia, Milan, Italy
J Clin Oncol 18:2702-9. 2000....
Response to cyclophosphamide, methotrexate, and fluorouracil in lymph node-positive breast cancer according to HER2 overexpression and other tumor biologic variablesS Menard
Molecular Targeting Unit, Department of Experimental Oncology, Scientific Direction, Istituto Nazionale Tumori, Milan, Italy
J Clin Oncol 19:329-35. 2001..In this study, we investigated this issue in the 386 breast cancer patients in the first CMF controlled clinical trial with a 20-year follow-up...
Effect of steroid receptors, pS2 and cathepsin D on the outcome of elderly breast cancer patients: an exploratory investigationD Coradini
Division of Experimental Oncology C, Istituto Nazionale per lo Studio e la Cura dei Tumori, Milan, Italy
Int J Cancer 79:305-11. 1998....
Feed forward neural networks for the analysis of censored survival data: a partial logistic regression approachE Biganzoli
Divsione di Statistica Medica e Biometria, Istituto Nazionale per lo Studio e la Cura dei Tumori, Milano, Italy
Stat Med 17:1169-86. 1998....
Modelling cause-specific hazards with radial basis function artificial neural networks: application to 2233 breast cancer patientsP Boracchi
Istituto di Statistica Medica e Biometria, Universita degli Studi di Milano, Via Venezian 1, 20133 Milan, Italy
Stat Med 20:3677-94. 2001..The adoption of a radial basis function network made it possible to highlight effects that were not considered by previous analyses of the same data...
Tecniche "high throughput" in patologia umana. Biostatistica. "High throughput" technique in human pathology. BiostatisticsE Biganzoli
Istituto Nazionale per lo Studio e la Cura dei Tumori, Unit, di Statistica Medica e Biometria, Milano, Italy
Pathologica 97:190-1. 2005
Biostatistics and tumor marker studies in breast cancer: design, analysis and interpretation issuesE Biganzoli
, Istituto Nazionale per lo Studio e la Cura dei Tumori, Milan, Italy
Int J Biol Markers 18:40-8. 2003
Markers of prognosis and response to treatment: ready for clinical use in oncology? A biostatistician's viewpointP Boracchi
Istituto di Statistica Medica e Biometria, , Milan, Italy
Int J Biol Markers 18:65-9. 2003
Double-contrast barium enema and computerised tomography in the pre-operative evaluation of rectal carcinoma: are they still useful diagnostic procedures?E M Civelli
Department of Radiology, Istituto Nazionale perlo Studio e la Cura dei Tumori, Milan, Italy
Tumori 86:389-92. 2000..DCBE and CT can therefore be usefully employed for staging of cancer of the rectum in those cases in which there are limitations of the current standard methods...
Quality of life and length of survival in advanced cancer patients on home parenteral nutritionF Bozzetti
Italian Society for Parenteral and Enteral Nutrition, Milan, Italy
Clin Nutr 21:281-8. 2002..Provided that these patients survive longer than 3 months, there is some evidence that QoL remains stable for some months and acceptable for the patients...
Prognostic role of serum CA15.3 in 362 node-negative breast cancers. An old player for a new gameM Gion
Centro Regionale per lo Studio degli Indicatori Biochimici di Tumore, Ospedale Civile, ULSS12 Venice, Italy
Eur J Cancer 38:1181-8. 2002..3 is a prognostic marker in node-negative breast cancer; (ii) its relationship with prognosis is continuous, with the risk of relapse increasing progressively from approximately 10 U/ml...
Thrombospondin-1 and -2 in node-negative breast cancer: correlation with angiogenic factors, p53, cathepsin D, hormone receptors and prognosisG Gasparini
Division of Medical Oncology, Azienda Complesso Ospedaliero 'San Filippo Neri, Rome, Italy
Oncology 60:72-80. 2001..On the contrary, TSP-1 and -2, potential naturally occurring negative regulators of angiogenesis, lacked prognostic value...
Angiogenesis sustains tumor dormancy in patients with breast cancer treated with adjuvant chemotherapyG Gasparini
Division of Medical Oncology, Azienda Ospedaliera S. Filippo Neri, Rome, Italy
Breast Cancer Res Treat 65:71-5. 2001..The clinical and therapeutic implications of our results are discussed...
