P Ragazzini

Summary

Affiliation: Istituti Ortopedici Rizzoli
Country: Italy

Publications

  1. ncbi Amplification of CDK4, MDM2, SAS and GLI genes in leiomyosarcoma, alveolar and embryonal rhabdomyosarcoma
    P Ragazzini
    Laboratory of Oncologic Research, Rizzoli Orthopaedic Institute, Bologna, Italy
    Histol Histopathol 19:401-11. 2004
  2. ncbi Alteration of pRb/p16/cdk4 regulation in human osteosarcoma
    M S Benassi
    Department of Musculoskeletal Oncology, Laboratory of Oncologic Research, Rizzoli Orthopedic Institute, Bologna, Italy
    Int J Cancer 84:489-93. 1999
  3. ncbi Involvement of INK4A gene products in the pathogenesis and development of human osteosarcoma
    M S Benassi
    Department of Musculoskeletal Oncology, Laboratory of Oncologic Research, Rizzoli Orthopedic Institute, Bologna, Italy
    Cancer 92:3062-7. 2001
  4. ncbi Increased c-myc oncogene expression in Ewing's sarcoma: correlation with Ki67 proliferation index
    M R Sollazzo
    Laboratorio di Ricerca Oncologica, Istituti Ortopedici Rizzoli, Bologna, Italy
    Tumori 85:167-73. 1999
  5. ncbi Metalloproteinase expression and prognosis in soft tissue sarcomas
    M S Benassi
    Laboratory of Oncologic Research, Rizzoli Orthopaedic Institute, Bologna, Italy
    Ann Oncol 12:75-80. 2001
  6. ncbi Proteases and interleukin-6 gene analysis in 92 giant cell tumors of bone
    G Gamberi
    Laboratory of Oncologic Research, Department of Musculoskeletal Oncology, Istituto Ortopedico Rizzoli, Bologna, Italy
    Ann Oncol 15:498-503. 2004
  7. ncbi Molecular alterations of monophasic synovial sarcoma: loss of chromosome 3p does not alter RASSF1 and MLH1 transcriptional activity
    L Pazzaglia
    Laboratory of Oncologic Research, Rizzoli Orthopaedic Institute, Bologna, Italy
    Histol Histopathol 21:187-95. 2006
  8. ncbi Presence and expression of the simian virus-40 genome in human giant cell tumors of bone
    G Gamberi
    Laboratory of Oncologic Research, Rizzoli Institute, Bologna, Italy
    Genes Chromosomes Cancer 28:23-30. 2000
  9. ncbi Tissue and serum loss of metalloproteinase inhibitors in high grade soft tissue sarcomas
    M S Benassi
    Oncological Research Laboratory, Istituti Ortopedici Rizzoli, Bologna, Italy
    Histol Histopathol 18:1035-40. 2003
  10. ncbi Analysis of SAS gene and CDK4 and MDM2 proteins in low-grade osteosarcoma
    P Ragazzini
    Laboratory of Oncologic Research, Rizzoli Orthopedic Institute, Bologna, Italy
    Cancer Detect Prev 23:129-36. 1999

Detail Information

Publications11

  1. ncbi Amplification of CDK4, MDM2, SAS and GLI genes in leiomyosarcoma, alveolar and embryonal rhabdomyosarcoma
    P Ragazzini
    Laboratory of Oncologic Research, Rizzoli Orthopaedic Institute, Bologna, Italy
    Histol Histopathol 19:401-11. 2004
    ..These two seem to have a more similar behavior than anaplastic and classic embryonal that are classified in the same subtype...
  2. ncbi Alteration of pRb/p16/cdk4 regulation in human osteosarcoma
    M S Benassi
    Department of Musculoskeletal Oncology, Laboratory of Oncologic Research, Rizzoli Orthopedic Institute, Bologna, Italy
    Int J Cancer 84:489-93. 1999
    ..These data confirm the role of the pRb/p16/cdk4 pathway in OS development...
  3. ncbi Involvement of INK4A gene products in the pathogenesis and development of human osteosarcoma
    M S Benassi
    Department of Musculoskeletal Oncology, Laboratory of Oncologic Research, Rizzoli Orthopedic Institute, Bologna, Italy
    Cancer 92:3062-7. 2001
    ..It encodes two transcripts, p16 and p14 alternate reading frame (ARF), involved in retinoblastoma protein (pRb)- and p53- cell growth control pathways, respectively...
  4. ncbi Increased c-myc oncogene expression in Ewing's sarcoma: correlation with Ki67 proliferation index
    M R Sollazzo
    Laboratorio di Ricerca Oncologica, Istituti Ortopedici Rizzoli, Bologna, Italy
    Tumori 85:167-73. 1999
    ..CONCLUSION: These results suggest a possible role of the c-myc oncogene and Ki67 antigen in the malignant progression of Ewing's sarcoma...
  5. ncbi Metalloproteinase expression and prognosis in soft tissue sarcomas
    M S Benassi
    Laboratory of Oncologic Research, Rizzoli Orthopaedic Institute, Bologna, Italy
    Ann Oncol 12:75-80. 2001
    ..This study assessed the prognostic role of MMP2, MMP9 metalloproteinases, and of the metalloproteinase inhibitor TIMP2, related to disease-free survival (DFS), in soft tissue sarcoma (STS) patients...
  6. ncbi Proteases and interleukin-6 gene analysis in 92 giant cell tumors of bone
    G Gamberi
    Laboratory of Oncologic Research, Department of Musculoskeletal Oncology, Istituto Ortopedico Rizzoli, Bologna, Italy
    Ann Oncol 15:498-503. 2004
    ..Few prognostic markers have been reported to predict the clinical outcome of GCT patients, so is very important to find the factor that can be implicated in its potential aggressiveness...
  7. ncbi Molecular alterations of monophasic synovial sarcoma: loss of chromosome 3p does not alter RASSF1 and MLH1 transcriptional activity
    L Pazzaglia
    Laboratory of Oncologic Research, Rizzoli Orthopaedic Institute, Bologna, Italy
    Histol Histopathol 21:187-95. 2006
    ..These findings confirm the genetic complexity of monophasic synovial sarcoma and underline the need to integrate different analyses for a better knowledge of this tumour, essential to investigate new diagnostic and prognostic markers...
  8. ncbi Presence and expression of the simian virus-40 genome in human giant cell tumors of bone
    G Gamberi
    Laboratory of Oncologic Research, Rizzoli Institute, Bologna, Italy
    Genes Chromosomes Cancer 28:23-30. 2000
    ..001). These results show that SV40 DNA sequences and SV40 Tag are present in GCTs and might induce FOS activity. These data suggest that SV40 might play a role in the development and progression of some GCTs...
  9. ncbi Tissue and serum loss of metalloproteinase inhibitors in high grade soft tissue sarcomas
    M S Benassi
    Oncological Research Laboratory, Istituti Ortopedici Rizzoli, Bologna, Italy
    Histol Histopathol 18:1035-40. 2003
    ..0001). In conclusion, low levels of negative regulators of proteolysis may be related to tumor biological aggressiveness and used to select patients with poor prognosis to improve cure...
  10. ncbi Analysis of SAS gene and CDK4 and MDM2 proteins in low-grade osteosarcoma
    P Ragazzini
    Laboratory of Oncologic Research, Rizzoli Orthopedic Institute, Bologna, Italy
    Cancer Detect Prev 23:129-36. 1999
    ..SAS was found amplified in 15% of the samples. These findings indicate that these genes may be involved in tumorigenesis and progression of low-grade osteosarcoma...
  11. ncbi Bone hemangioendothelioma: an immunohistochemical study related to histological malignancy and proliferative activity (NORs)
    M S Benassi
    Laboratory of Oncologic Research, Rizzoli Orthopaedic Institute, Bologna, Italy
    Tumori 81:179-84. 1995
    ..CONCLUSIONS: The mean nucleolar organizer region (NOR) area, as a measure of cell proliferation, was significantly higher in grade 4 malignancies than in lower grades, revealing novel prognostic parameters...