Sandro Giannini

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..Congenital brachymetatarsia, a shortened metatarsal bone, can be corrected surgically by callus distraction or one-stage lengthening using bone graft...

..The aim of this study was to examine the capacity of chondrocytes harvested from a detached osteochondral fragment to proliferate and to serve as a source of viable cells for ACI in the repair of ankle cartilage defects...

..Level of Evidence: Therapeutic study, Level IV. See the Guidelines for Authors for a complete description of levels of evidence...

..Seven patients affected by Duchenne muscular dystrophy with neck hyperextension or poor head control in extension have undergone surgery consisting of posterior cervical interspinous fusion...

..Autologous chondrocyte implantation (ACI) in the ankle was considered up to now an extremely technically demanding surgery with considerable morbidity for the patients...

..For these reasons, we may hypothesise that the use of BMMCs has a role in the re-building of large segmental defects...

..The aim of this study was to retrospectively evaluate the results of a series of 50 consecutive feet affected by symptomatic bunionette deformity treated by S.E.R.I. (simple, effective, rapid, inexpensive) osteotomy...

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..In this review, the aforementioned methods of operative treatment are examined and issues that are related to these methods are discussed...

..The precise etiology of interdigital neuroma remains obscure...

..Moreover, once a correct alignment of the joint is achieved, secondary surgery, if necessary, can be performed more easily, and with better results...

..The use of growth factors and new tissue engineering techniques in the future would simplify the methodology, rendering it less invasive and more effective...

..quot; In fact, health care and economic aid are integrated with the safety and rehabilitation of the worker and his or her return to family, social, and working life...

..to 91/100 points at 24 months of follow up was obtained. Laboratory data have confirmed the presence of reconstructed cartilage with chondrocytes and expression of collagen II, characteristic of hyaline cartilage...

..e., accurate rotation-translation at the replaced knee and complete locomotion patterns at both lower limb joints, suggested that bi-cruciate substituting arthroplasty can restore physiological knee motion and normal overall function...

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..0005). Histological analysis showed good osteointegration of the two coated pin types. This study shows that HA-coating is more important for optimal pin fixation than the particular combination of design parameters used in each pin type...

..To evaluate whether fixing a locking compression plate (LCP) with hydroxyapatite (HA)-coated screws provides improved biomechanical fixation and healing compared with standard screws under loaded conditions...

..LEVEL OF EVIDENCE: Level IV, therapeutic study. See Guidelines for Authors for a complete description of levels of evidence...

..The aim of this study was to describe a lateral trans-malleolar technique for BFOA, and to evaluate the results in a case series...

..Osteochondritis dissecans is a relatively common cause of knee pain. The aim of this study was to describe the outcomes of five different surgical techniques in a series of sixty patients with osteochondritis dissecans...

..0005). The survival after 6 years was 97.8% overall and 98.5% (excluding a post traumatic femoral neck fracture). These good medium-term results suggest that HR is an effective procedure in young and active patients...

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..The main purpose of this study was to investigate the persistence of the beneficial effects observed...

..3° (5.1-18.0°), respectively. The pivot point for these lines was found mostly in the central area of the base-plate. Nearly physiological range of axial rotation can be achieved at the replaced knee during activities of daily living...

..The aim of this study was to evaluate the mid-term results of a series of patients arthroscopically treated by ACI and investigate the nature of the repair tissue by MRI T2 mapping...

..In followup studies, various authors have noted clinically relevant adjacent-level degeneration. However, factors associated with adjacent-level degeneration are not well known...

..The aim of this study was to use gait analysis to compare the functional performance of patients who underwent TAR versus a control population...

..The tapered stem achieved adequate stability and orientation, and may be a suitable option for total hip arthroplasty for arthritis following developmental hip dysplasia...

..0001). These studies demonstrate that with the use of hydroxyapatite-coated pins, no deterioration of pin fixation occurs, and that there is no significant pin loosening and infection, regardless of bone type and loading conditions...

..Unlike all current prostheses, the new design uses nonanatomically shaped components on the tibia and talus and a fully conforming interposed meniscal bearing...

..Their consistence provides fundamental information to understand orthopedic treatment of the knee and for possible relevant measurements intraoperatively...

..The aim of this study was to measure the alignment deviation caused by standard impaction of the tibial and femoral components following bone resections with use of navigation control...

..To evaluate whether coating AO/ASIF screws with osteoconductive materials can improve bone-screw fixation...

..There is biomechanical evidence that a limb lengthening of up to two centimetres after THA in general does not need to be corrected by means of a contralateral shoe lift. Individual decisions to the contrary need to be justified...

..This study compares the biomechanics of the knee in patients after total knee arthroplasty with and without patellar resurfacing during stair climbing...

..Articular surface conformity restores physiological rollback in the presence of a spine-cam mechanism, but not coherently in the presence of the posterior cruciate ligament...

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..This study evaluates the results in terms of pain and disability of intra-articular injections of hyaluronan derivates into the ankle joint in patients suffering from grade II primary or secondary osteoarthritis of the ankle...

..Furthermore, magnetic resonance imaging T2 mapping is becoming an increasingly used method for noninvasive assessment of repair tissue in the knee, but no experience on the ankle has been reported...

..Therefore, we compared the two treatments in a clinical trial of elderly patients with pertrochanteric fracture...

..Among the various pin types coated with hydroxyapatite, the best results were obtained with the tapered pins...

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..The two groups were isokinetically similar. In this study, the percutaneous and minimally invasive techniques of repair of the Achilles tendon yielded essentially identical clinical and functional outcomes...

..Therefore, when choosing an allograft tendon, particular care is needed to choose a biomechanically suitable graft...

..We assessed a series of patients affected by developmental hip dysplasia treated with total hip arthroplasty using cementless tapered stem and here we report the outcomes at long-term follow-up...

..The aim of our study is to compare the efficacy of platelet-rich plasma (PRP) and viscosupplementation (hyaluronic acid [HA]) intra-articular injections for the treatment of knee cartilage degenerative lesions and osteoarthritis (OA)...

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..These positive results should be confirmed at a longer follow-up in a large cohort of patients...

..Level of Evidence: Level III, therapeutic study. See the Guidelines for Authors for a complete description of levels of evidence...

..Functional assessment by specific tests should be included in the examination, as evidence exists that morphology and function are not necessarily related...

..HR preserves the bone-stock of the proximal femur. When the femoral component is implanted in a valgus position BMD is further enhanced, thus potentially reducing the risk of femoral neck fractures...

..Therefore, stem tip migration occurred at the bone-cement interface. Key words: total hip arthroplasty, anatomic stem, radiostereometry, subsidence, bone-cement interface...

..3 ±?3.1%) compared to the control group (mean 0.2 ±?0.1%). The results indicate that MSC and PL in a fibrin or collagen scaffold can promote NB formation around an uncemented hip prosthesis stem...

..The aim of this paper was to report the results of treating closed displaced midshaft clavicle fractures nonoperatively...

..LEVEL OF EVIDENCE: Level IV, therapeutic study. See the Guidelines for Authors for a complete description of levels of evidence...

..Radiographic assessment is still used to evaluate flexible flatfoot in children...

..Therefore, both pin types are recommended for tibial fixation. However, the tapered pins showed higher extraction torque, an important result for external fixation treatments...

..The outcome of both procedures is reported. In addition, the treatment technique of CT-guided percutaneous injections of demineralized bone matrix mixed with bone marrow concentrate is described...

..Consequently, we suggest that restoring the original posterior slope of the tibial plateau must be a goal of tibial component implantation...

..Although the fracture was evident on the MRI, the findings were subtle and overlooked. The fracture was later confirmed by CT and radiograph, showing the reparative process...

..0005). The preliminary results indicate that the treatment with PRP injections is safe and has the potential to reduce pain and improve knee function and quality of live in younger patients with low degree of articular degeneration...

..0.17). We can conclude that the VDR genotype polymorphism affects bone density of renal transplant recipients via its effects on the severity of SHPT...

..Recent studies have described the subtalar joint as a structure with no degrees of unresisted freedom, i.e., motion from the single neutral position is attained only by deformation of the ligaments and of the articular surfaces...

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..Surgical treatment of talocalcaneal coalition seems to be effective in restoring more physiologic subtalar and forefoot motion and loading patterns...

..The aim of this study was to verify whether reduced INSL3 activity could cause or contribute to some signs of hypogonadism, such as reduced BMD, currently attributed to testosterone deficiency...

..To establish reference values for fat-free mass (FFM), the FFM index (FFMI), fat mass (FM) and the FM index (FMI) in an Italian adult population, developing percentile distribution curves for age brackets between 20 and 80 years...

..A low 1 mCi Sestamibi dose appears sufficient to perform MIRP. Patients with concomitant Sestamibi avid thyroid nodules should be excluded from MIRP...

..Amino-bisphosphonates induced a significant increase of apoptosis in MCF-7. In addition, they showed a significant decrease in telomerase expression and activity with respect to control and to clodronate...

..Vertebral fractures should be looked for carefully in all post-menopausal women receiving long-term systemic GCs since they can be asymptomatic and are scarcely predictable...

..For its probable safety and excellent feasibility and cost-effectiveness, this primary intervention has a great potential for generalisability...

..The aim of the present study was to define the efficacy of minimally invasive radioguided surgery (MIRS) in PHPT patients with a high probability of a solitary PA with particular regard to benefits achievable in elderly patients...

..They were 45-88 years of age and had been referred for their first visit to our Unit for Metabolic Bone Diseases over a 2-year period because of primary osteoporosis (bone density T-score < -2.5)...

..This review provides a comprehensive overview of the anti-fracture efficacy of bisphosphonates at the spine, hip, and non-vertebral sites...

..Risk factors usually associated to BMD as measured by DXA are also associated to calcaneal bone stiffness as measured by QUS, and most risk factors for osteoporosis usually observed in women are equally applicable to men...

..0.17). We can conclude that the VDR genotype polymorphism affects bone density of renal transplant recipients via its effects on the severity of SHPT...