Sergio BoniniSummaryAffiliation: IRCCS San Raffaele Country: Italy Publications
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Publications
Allergic conjunctivitis: the forgotten diseaseSergio Bonini
Chair Allergology and Clinical Immunology, Second University of Naples and IRCCS San Raffaele, Rome, Italy
Chem Immunol Allergy 91:110-20. 2006..In particular, the classification of the various forms of a 'red eye' of allergic origin appears inadequate to answer the progress achieved in their multifactorial pathogenesis...
The hygiene hypothesis: does it function worldwide?Megon Bresciani
IRCCS San Raffaele Pisana, Research Center, Rome, Italy
Curr Opin Allergy Clin Immunol 5:147-51. 2005....
The hygiene hypothesis: epidemiologic evidenceSergio Bonini
Consiglio Nazionale Richerche, Rome, Italy
J Pediatr Gastroenterol Nutr 40:S37-8. 2005
Development and testing of the quality of life in children with vernal keratoconjunctivitis questionnaireMarta Sacchetti
Department of Ophthalmology, University of Rome Campus Bio Medico, Rome, Italy
Am J Ophthalmol 144:557-63. 2007..To develop and validate a questionnaire that measures health-related quality of life (HRQoL) in children with vernal keratoconjunctivitis (VKC)...
Nerve growth factor has a modulatory role on human primary fibroblast cultures derived from vernal keratoconjunctivitis-affected conjunctivaAlessandra Micera
CIR Laboratory of Ophthalmology, University Campus Bio Medico, Rome, Italy
Mol Vis 13:981-7. 2007..NGF, a pleiotrophic factor with documented profibrogenic activities, is produced by inflammatory and structural cells populating the VKC conjunctiva and is increased in the serum and tears of VKC patients...
Conjunctival expression of thymosin-beta4 in vernal keratoconjunctivitisAlessandra Micera
Istituto di Ricovero e Cura a Carattere Scientifico Gian Battista Bietti Eye Foundation and CIR, Laboratory of Ophthalmology, University Campus Bio Medico, Rome, Italy
Mol Vis 12:1594-600. 2006....
Allergic bronchial airway inflammation in nerve growth factor (NGF)-deprived rats: evidence suggesting a neuroimmunomodulatory role of NGFBarbara Stampachiacchiere
Institute of Neurobiology and Molecular Medicine, Section of Neurobiology, National Research Council CNR, Rome, Italy
Exp Lung Res 32:305-20. 2006..The present findings suggest that at least NGF does not act as a proper proinflammatory factor but most probably as a neuroimmune modulator molecule of the allergic state...
Nerve growth factor modulates toll-like receptor (TLR) 4 and 9 expression in cultured primary VKC conjunctival epithelial cellsAlessandra Micera
CIR, Laboratory of Ophthalmology, University Campus Bio Medico, Rome, Italy
Mol Vis 15:2037-44. 2009..To investigate if nerve growth factor (NGF) might modulate toll-like receptor (TLR) 4 and 9 expression in primary cultures of vernal keratoconjunctivitis (VKC)-derived conjunctival epithelial cells (VKC-ECs)...
Expression of Toll-like receptors in healthy and allergic conjunctivaStefano Bonini
CIR Laboratory of Ophthalmology, Campus Bio Medico and G B Bietti Eye Foundation, Rome, Italy
Ophthalmology 112:1528; discussion 1548-9. 2005..To investigate the expression of toll-like receptors (TLRs) in healthy and active vernal keratoconjunctivitis (VKC) conjunctiva...
Nerve growth factor involvement in the visual system: implications in allergic and neurodegenerative diseasesAlessandra Micera
CIR Laboratorio di Oftalmologia, Campus Bio-Medico and Fondazione GB Bietti, Rome, Italy
Cytokine Growth Factor Rev 15:411-7. 2004..The present review of experimental and clinical studies will highlight old and recent strategies for treating ocular surface and tear disorders with NGF...
Cytokines in ocular allergyStefano Bonini
Institute of Neurobiology and Molecular Medicine, National Research Council, Rome, Italy
Int Ophthalmol Clin 43:27-32. 2003
Montelukast, a leukotriene receptor antagonist, in vernal keratoconjunctivitis associated with asthmaAlessandro Lambiase
Interdisciplinary Research Center, University Campus Bio-Medico, Laboratory of Ophthalmology, Rome, Italy
Arch Ophthalmol 121:615-20. 2003....
Nerve growth factor and the immune system: old and new concepts in the cross-talk between immune and resident cells during pathophysiological conditionsAlessandro Lambiase
CIR Ophthalmology Laboratory, Campus Bio-Medico' and G.B. Bietti Eye Foundation, and San Raffaele H Research, Rome, Italy
Curr Opin Allergy Clin Immunol 4:425-30. 2004..Understanding these complex mechanisms will introduce new therapeutic approaches for nerve growth factor in the immune system, in addition to those already established in the nervous system...
Allergic chronic inflammation of the ocular surface in vernal keratoconjunctivitisStefano Bonini
Interdisciplinary Center for Biomedical Research CIR Laboratory of Ophthalmology, University of Rome Campus Bio Medico, and G B Bietti Eye Foundation, Italy
Curr Opin Allergy Clin Immunol 3:381-7. 2003....
Nerve growth factor and tissue repair remodeling: trkA(NGFR) and p75(NTR), two receptors one fateAlessandra Micera
Department of Pharmacology, School of Pharmacy, Faculty of Medicine, The Hebrew University of Jerusalem, Israel
Cytokine Growth Factor Rev 18:245-56. 2007..In summary, these novel findings on the potential pro-healing capacity of NGF might open new possibilities for this growth factor in modulating the healing processes in several pathological conditions...
Hyperosmolar conjunctival provocation for the evaluation of nonspecific hyperreactivity in healthy patients and patients with allergyMarta Sacchetti
Department of Ophthalmology, University of Rome, Campus Bio-Medico, Italy
J Allergy Clin Immunol 118:872-7. 2006..CLINICAL IMPLICATIONS: Hyperosmolar provocation test may be useful for identifying conjunctival hyperreactivity in subjects with and without allergy with a history of ocular discomfort...
Practice evidence to put evidence into practiceBarbara Caracciolo
Allergy 59:1165-7. 2004
Practical approach to diagnosis and treatment of ocular allergy: a 1-year systematic reviewSergio Bonini
Second University of Naples, Naples, Italy
Curr Opin Allergy Clin Immunol 7:446-9. 2007..A 1-year systematic review in the field of ocular allergy was carried out to select new information which may be useful for a practical approach to allergic conjunctivitis...
Natural killer cells in vernal keratoconjunctivitisAlessandro Lambiase
Interdisciplinary Center for Biomedical Research CIR, Laboratory of Ophthalmology, University Campus Bio Medico of Rome, Italy
Mol Vis 13:1562-7. 2007..The aim of this study was to evaluate NK in the blood and the conjunctiva of patients with vernal keratoconjunctivitis (VKC)...
The elite athlete: yes, with allergy we canSergio Bonini
J Allergy Clin Immunol 122:249-50. 2008
Allergic eye disordersLeonard Bielory
UMDNJ-New Jersey Medical School, Newark, New Jersey, USA
Clin Allergy Immunol 16:311-23. 2002
