Giuseppe Legname

Summary

Affiliation: International School for Advanced Studies
Country: Italy

Publications

  1. ncbi A novel class of potential prion drugs: preliminary in vitro and in vivo data for multilayer coated gold nanoparticles
    Hoang Ngoc Ai Tran
    Laboratory of Prion Biology, Neurobiology Sector, Scuola Internazionale Superiore di Studi Avanzati SISSA, Ed Q1, Basovizza Campus, S S 14 Km 163, 5, 34149, Trieste, Italy
    Nanoscale 2:2724-32. 2010
  2. ncbi Early structural features in mammalian prion conformation conversion
    Giuseppe Legname
    Laboratory of Prion Biology, Neurobiology Sector, Scuola Internazionale Superiore di Studi Avanzati SISSA, Trieste, Italy
    Prion 6:37-9. 2012
  3. ncbi Aberrant ERK 1/2 complex activation and localization in scrapie-infected GT1-1 cells
    Alessandro Didonna
    Laboratory of Prion Biology, Neurobiology Sector, Scuola Internazionale Superiore di Studi Avanzati SISSA, via Bonomea 265, I 34136 Trieste, Italy
    Mol Neurodegener 5:29. 2010

Collaborators

  • Alessandro Didonna
  • Hoang Ngoc Ai Tran
  • Silke Krol
  • Munish Chanana
  • Michela Morbin
  • Fabrizio Tagliavini
  • Chiara Vimercati
  • Subhra Mandal
  • Fernanda Sousa
  • Fabio Moda

Detail Information

Publications3

  1. ncbi A novel class of potential prion drugs: preliminary in vitro and in vivo data for multilayer coated gold nanoparticles
    Hoang Ngoc Ai Tran
    Laboratory of Prion Biology, Neurobiology Sector, Scuola Internazionale Superiore di Studi Avanzati SISSA, Ed Q1, Basovizza Campus, S S 14 Km 163, 5, 34149, Trieste, Italy
    Nanoscale 2:2724-32. 2010
    ..Finally, incubation periods of prion-infected mice treated with nanomolar concentrations of gold nanoparticles were significantly longer compared to untreated controls...
  2. ncbi Early structural features in mammalian prion conformation conversion
    Giuseppe Legname
    Laboratory of Prion Biology, Neurobiology Sector, Scuola Internazionale Superiore di Studi Avanzati SISSA, Trieste, Italy
    Prion 6:37-9. 2012
    ..Recent experimental data support these findings, thus opening novel approaches to determine initial structural determinants of prion formation...
  3. ncbi Aberrant ERK 1/2 complex activation and localization in scrapie-infected GT1-1 cells
    Alessandro Didonna
    Laboratory of Prion Biology, Neurobiology Sector, Scuola Internazionale Superiore di Studi Avanzati SISSA, via Bonomea 265, I 34136 Trieste, Italy
    Mol Neurodegener 5:29. 2010
    ..The latter derives from the host cellular form, PrPC, through a process whereby portions of its alpha-helical and coil structures are refolded into beta-sheet structures...