A Serafino

Summary

Affiliation: Institute of Neurobiology and Molecular Medicine
Country: Italy

Publications

  1. ncbi Differentiation of human melanoma cells induced by cyanidin-3-O-beta-glucopyranoside
    Annalucia Serafino
    Institute of Neurobiology and Molecular Medicine, National Research Council, Rome, Italy
    FASEB J 18:1940-2. 2004
  2. ncbi Phenotypic and genotypic characteristics of new euploid-diploid lymphoblastoid B cell lines EBV+, normal human bone marrow derived, spontaneously overgrown in vitro
    Luisa Bertolini
    Istituto di Neorobiologia e Medicina Molecolare, CNR, Via del Fosso del Cavaliere, 100, 00133 Rome, Italy
    J Virol Methods 126:91-100. 2005
  3. ncbi Resveratrol down-regulates the growth and telomerase activity of breast cancer cells in vitro
    Giulia Lanzilli
    Institute of Neurobiology and Molecular Medicine, CNR, Area Ricerca Roma Tor Vergata, I 00133 Rome, Italy
    Int J Oncol 28:641-8. 2006
  4. ncbi Gene expression profiling of human macrophages at late time of infection with Mycobacterium tuberculosis
    Elisabetta Volpe
    Department of Biology, University of Rome Tor Vergata, Rome, Italy
    Immunology 118:449-60. 2006
  5. ncbi Delayed internalization and lack of recycling in a beta2-adrenergic receptor fused to the G protein alpha-subunit
    Maria Grazia Di Certo
    Istituto di Neurobiologia e Medicina Molecolare, CNR, c o Fondazione Santa Lucia EBRI, via del Fosso di Fiorano 64 65, 00143 Rome, Italy
    BMC Cell Biol 9:56. 2008
  6. ncbi The activation of human endogenous retrovirus K (HERV-K) is implicated in melanoma cell malignant transformation
    A Serafino
    Institute of Neurobiology and Molecular Medicine ARTOV, CNR via Fosso del Cavaliere 100, 00133 Rome, Italy
    Exp Cell Res 315:849-62. 2009
  7. ncbi Stimulatory effect of Eucalyptus essential oil on innate cell-mediated immune response
    Annalucia Serafino
    Institute of Neurobiology and Molecular Medicine ARTOV, CNR, Via Fosso del Cavaliere 100, 00133 Rome, Italy
    BMC Immunol 9:17. 2008
  8. ncbi N-acetyl-l-cysteine fosters inactivation and transfer to endolysosomes of c-Src
    Ewa K Krasnowska
    Istituto di Neurobiologia e Medicina Molecolare, CNR, Rome, Italy
    Free Radic Biol Med 45:1566-72. 2008
  9. ncbi Gap junction channels reconstituted in two closely apposed lipid bilayers
    Alfonsina Ramundo-Orlando
    Institute of Neurobiology and Molecular Medicine, National Research Council Via del Fosso del Cavaliere, 00133 Rome, Italy
    Arch Biochem Biophys 436:128-35. 2005
  10. ncbi Modifications of mitochondria in human tumor cells during anthracycline-induced apoptosis
    A Serafino
    Institute of Experimental Medicine, Research Area of Rome Tor Vergata, National Research Council, Via Fosso del Cavaliere 100, Rome, Italy
    Anticancer Res 20:3383-94. 2000

Collaborators

  • Alberto Fruscalzo
  • Giulia Lanzilli
  • B Tavazzi
  • F Pica
  • C Spadafora
  • O Franzese
  • Antonella Lisi
  • Tiziana Parasassi
  • Maria Grazia Di Certo
  • Alfonsina Ramundo-Orlando
  • L Romani
  • M Cerquetti
  • C Puoti
  • A Martino
  • Giuseppe Lazzarino
  • Matteo Landriscina
  • Mara Ceridono
  • Nadia Canu
  • M Piacentini
  • Luisa Bertolini
  • Ewa K Krasnowska
  • Christian Barbato
  • Vanessa Manni
  • Guido Rasi
  • Paola Sinibaldi Vallebona
  • Enrico Garaci
  • Pietro Calissano
  • Esther Edlundh-Rose
  • Maria Teresa Ciotti
  • Anna C Gustafsson
  • Giulia Greco
  • Maria Beatrice Valli
  • Anna Teresa Palamara
  • Pasquale Pierimarchi
  • Elisabetta Volpe
  • Luisa Bracci-Laudiero
  • Ilya Kupershmidt
  • Thomas Lundeberg
  • Maria-Concetta Romano
  • Ilaria Sciamanna
  • Joakim Lundeberg
  • Laura Falasca
  • Guido Carloni
  • Gelsomina De Stasio
  • Settimio Grimaldi
  • Arturo Romano
  • Livio Giuliani
  • Sabrina Rieti
  • Francesca Belleudi
  • Anna Maria Brunati
  • Eugenia Pittaluga
  • Fulvio Ursini
  • Marco De Spirito
  • Roberto Brunelli
  • Graziella Costa
  • Carlo Cogoni
  • Cartesio Favalli
  • Stefano Menzo
  • Giuseppe Maria Ettorre
  • Antonio Ponzetto
  • Francesco Bistoni
  • Gianpietro Ravagnan
  • Maria Teresa Lonardo
  • Giovanni Vennarecci
  • Lia Bellis
  • Annalisa Crema
  • Federica Andreola
  • Manuela Zonfrillo
  • Massimo Clementi
  • Claudia Matteucci
  • Eugenio Santoro
  • Antonio Mastino
  • Giulia Cappelli
  • Francesca Mariani
  • Vittorio Colizzi
  • Nunzia Sanarico
  • Manuela Grassi
  • Paola Sinibaldi-Vallebona
  • Rosanna Beraldi
  • Maria Luisa Aebischer
  • Peter Nilsson
  • Giuseppina Amadoro
  • Elisabetta Mattei
  • Alberto Faggioni
  • Franco Ameglio
  • Isabella Delaroche
  • Antonio Angeloni
  • Tommaso Russo
  • Alessandra Cassano
  • Valentina Iadevaia

Detail Information

Publications32

  1. ncbi Differentiation of human melanoma cells induced by cyanidin-3-O-beta-glucopyranoside
    Annalucia Serafino
    Institute of Neurobiology and Molecular Medicine, National Research Council, Rome, Italy
    FASEB J 18:1940-2. 2004
    ..We conclude that C-3-G is a very promising molecule to include in the strategies for treatment of melanoma; also because of its nutritional relevance...
  2. ncbi Phenotypic and genotypic characteristics of new euploid-diploid lymphoblastoid B cell lines EBV+, normal human bone marrow derived, spontaneously overgrown in vitro
    Luisa Bertolini
    Istituto di Neorobiologia e Medicina Molecolare, CNR, Via del Fosso del Cavaliere, 100, 00133 Rome, Italy
    J Virol Methods 126:91-100. 2005
    ..These tests were planned to characterize more fully this panel of new bone marrow cell lines sharing normal B cell traits...
  3. ncbi Resveratrol down-regulates the growth and telomerase activity of breast cancer cells in vitro
    Giulia Lanzilli
    Institute of Neurobiology and Molecular Medicine, CNR, Area Ricerca Roma Tor Vergata, I 00133 Rome, Italy
    Int J Oncol 28:641-8. 2006
    ..These results speak in favor of a potential role of resveratrol in chemoprevention/chemotherapy of breast cancer...
  4. ncbi Gene expression profiling of human macrophages at late time of infection with Mycobacterium tuberculosis
    Elisabetta Volpe
    Department of Biology, University of Rome Tor Vergata, Rome, Italy
    Immunology 118:449-60. 2006
    ..The identified host and mycobacterial genes that were expressed until 7 days after infection, could have a role in the interplay between the host immune defences and the bacterial escape mechanisms...
  5. ncbi Delayed internalization and lack of recycling in a beta2-adrenergic receptor fused to the G protein alpha-subunit
    Maria Grazia Di Certo
    Istituto di Neurobiologia e Medicina Molecolare, CNR, c o Fondazione Santa Lucia EBRI, via del Fosso di Fiorano 64 65, 00143 Rome, Italy
    BMC Cell Biol 9:56. 2008
    ..To further investigate this phenomenon, we have compared the rates of internalization and recycling between wild-type and Galphas-fused beta2AR...
  6. ncbi The activation of human endogenous retrovirus K (HERV-K) is implicated in melanoma cell malignant transformation
    A Serafino
    Institute of Neurobiology and Molecular Medicine ARTOV, CNR via Fosso del Cavaliere 100, 00133 Rome, Italy
    Exp Cell Res 315:849-62. 2009
    ..Down-regulation of HERV-K expression by RNA interference prevents the transition from the adherent to the non-adherent growth phenotype in low serum. These results implicate HERV-K in at least some critical steps of melanoma progression...
  7. ncbi Stimulatory effect of Eucalyptus essential oil on innate cell-mediated immune response
    Annalucia Serafino
    Institute of Neurobiology and Molecular Medicine ARTOV, CNR, Via Fosso del Cavaliere 100, 00133 Rome, Italy
    BMC Immunol 9:17. 2008
    ....
  8. ncbi N-acetyl-l-cysteine fosters inactivation and transfer to endolysosomes of c-Src
    Ewa K Krasnowska
    Istituto di Neurobiologia e Medicina Molecolare, CNR, Rome, Italy
    Free Radic Biol Med 45:1566-72. 2008
    ..With the objective of deciphering the complex issue of c-Src regulation and of devising new strategies to revert its activation in cancers, redox regulation thus emerges as a promising area for study...
  9. ncbi Gap junction channels reconstituted in two closely apposed lipid bilayers
    Alfonsina Ramundo-Orlando
    Institute of Neurobiology and Molecular Medicine, National Research Council Via del Fosso del Cavaliere, 00133 Rome, Italy
    Arch Biochem Biophys 436:128-35. 2005
    ..Future use of this model system has the potential to improve our understanding of the permeability and modulation of junctional channels in its native intercellular assembly...
  10. ncbi Modifications of mitochondria in human tumor cells during anthracycline-induced apoptosis
    A Serafino
    Institute of Experimental Medicine, Research Area of Rome Tor Vergata, National Research Council, Via Fosso del Cavaliere 100, Rome, Italy
    Anticancer Res 20:3383-94. 2000
    ..Our results indicated that mitochondria are actively involved in anthracycline-induced programmed cell death, suggesting a novel mechanism that may be common to all forms of apoptosis...
  11. ncbi Autocrine nerve growth factor is essential for cell survival and viral maturation in HHV-8-infected primary effusion lymphoma cells
    F Pica
    Departments of Experimental Medicine and Biochemical Sciences, Public Health and Cell Biology, and Neuroscience, University of Rome, Tor Vergata, Rome, Italy
    Blood 95:2905-12. 2000
    ..These data indicate that NGF is essential for both cell survival and virus maturation in HHV-8-infected cell lines. (Blood. 2000;95:2905-2912)..
  12. ncbi Permeability changes of connexin32 hemi channels reconstituted in liposomes induced by extremely low frequency, low amplitude magnetic fields
    Alfonsina Ramundo-Orlando
    Institute of Neurobiology and Molecular Medicine, CNR, Via del Fosso del Cavaliere 100, 00133 Rome, Italy
    Biochim Biophys Acta 1668:33-40. 2005
    ..Although the observed effect was very low, it seems to confirm the applicability of our model previously proposed for the interaction of low frequency electromagnetic fields with lipid membrane...
  13. ncbi Differentiation of normal and cancer cells induced by sulfhydryl reduction: biochemical and molecular mechanisms
    T Parasassi
    Istituto di Neurobiologia e Medicina Molecolare, CNR, Viale Marx 15 43, 00137 Roma, Italy
    Cell Death Differ 12:1285-96. 2005
    ....
  14. ncbi Binding of Clostridium difficile to Caco-2 epithelial cell line and to extracellular matrix proteins
    Marina Cerquetti
    Laboratory of Bacteriology and Medical Mycology, Istituto Superiore di Sanita, Rome, Italy
    FEMS Immunol Med Microbiol 32:211-8. 2002
    ..Furthermore, binding of C. difficile C253 to several extracellular matrix proteins in vitro was demonstrated by an ELISA-based assay...
  15. ncbi Effect of extremely low frequency electromagnetic fields (ELF-EMF) on Kaposi's sarcoma-associated herpes virus in BCBL-1 cells
    Francesca Pica
    Department of Experimental Medicine and Biochemical Sciences, University of Rome Tor Vergata, Rome, Italy
    Bioelectromagnetics 27:226-32. 2006
    ..1A/B (P < .01), but not with percentage of gp K8.1A/B-positive cells or of cells containing virions. Viral progeny produced under ELF-EMF exposure consisted mainly of defective viral particles...
  16. ncbi Thymosin alpha 1: from bench to bedside
    Enrico Garaci
    University of Rome Tor Vergata, Rome, Italy
    Ann N Y Acad Sci 1112:225-34. 2007
    ....
  17. ncbi Molecular and cellular determinants of cell-to-cell transmission of HCV in vitro
    Maria Beatrice Valli
    Institute of Neurobiology and Molecular Medicine, National Research Council CNR, Roma, Italy
    J Med Virol 79:1491-9. 2007
    ..These observations may provide an explanation for the establishment of HCV infection, the occurrence of chronic infection and HCV-related lymphoproliferative diseases...
  18. ncbi Nerve growth factor involvement in liver cirrhosis and hepatocellular carcinoma
    Guido Rasi
    National Research Council, Istituto di Neurobiologia e Medicina Molecolare, Via Fosso del Cavaliere 100, 00133 Rome, Italy
    World J Gastroenterol 13:4986-95. 2007
    ..To define NGF (nerve growth factor) and its high-affinity receptor trkA(NGF) presence and distribution in fibrotic liver and in HCC, and to verify if NGF might have a role in fibrosis and HCC...
  19. ncbi Low cell dosage of lymphoblastoid human cell lines EBV(+) is associated to chronic hepatitis in a minority of inoculated Nu/Nu mice
    Luisa Bertolini
    Istituto di Biologia Cellulare Consiglio Nazionale delle Ricerche (CNR, Rome, Italy
    J Med Virol 66:70-81. 2002
    ..These data show that we succeeded in dissecting the infectious from the proliferative activity of the endogenous EBV carrier CE cell line. This provides in addition a promising model for chronic EBV-associated hepatitis...
  20. ncbi Low electromagnetic field (50 Hz) induces differentiation on primary human oral keratinocytes (HOK)
    Vanessa Manni
    Istituto di Neurobiologia e Medicina Molecolare (INeMM, CNR, Rome, Italy
    Bioelectromagnetics 25:118-26. 2004
    ..These observations support the hypothesis that 50 Hz electromagnetic fields may modify cell morphology and interfere in differentiation and cellular adhesion of normal keratinocytes...
  21. ncbi Cidofovir on HHV-8 in BCBL-1 cells
    Francesca Pica
    Department of Experimental Medicine and Biochemical Sciences, University of Rome Tor Vergata, Rome, Italy
    Antivir Ther 9:823-5. 2004
  22. ncbi Suggested role of the Golgi apparatus and endoplasmic reticulum for crucial sites of hepatitis C virus replication in human lymphoblastoid cells infected in vitro
    Annalucia Serafino
    Institute of Neurobiology and Molecular Medicine, National Research Council, Rome, Italy
    J Med Virol 70:31-41. 2003
    ....
  23. ncbi Global gene expression analysis in time series following N-acetyl L-cysteine induced epithelial differentiation of human normal and cancer cells in vitro
    Anna C Gustafsson
    Department of Biotechnology, Royal Institute of Technology, AlbaNova University Center, Roslagstullsbacken 21, SE 106 91 Stockholm, Sweden
    BMC Cancer 5:75. 2005
    ....
  24. ncbi Interaction of Tau with Fe65 links tau to APP
    Christian Barbato
    Dipartimento di Neuroscienze, , Via Montpellier 1, 00133 Roma, Italy
    Neurobiol Dis 18:399-408. 2005
    ..These findings open new perspectives for the study of the possible crosstalk between these proteins in the pathogenesis of AD...
  25. ncbi Inhibition of endogenous reverse transcriptase antagonizes human tumor growth
    Ilaria Sciamanna
    Istituto Superiore di Sanit, Viale Regina Elena 299, Via del Castro Laurenziano 25, 00161 Rome, Italy
    Oncogene 24:3923-31. 2005
    ..Based on these data, the endogenous RT can be regarded as an epigenetic regulator of cell differentiation and proliferation and may represent a novel target in cancer therapy...
  26. ncbi Gene expression analysis of human epidermal keratinocytes after N-acetyl L-cysteine treatment demonstrates cell cycle arrest and increased differentiation
    Esther Edlundh-Rose
    Department of Biotechnology, AlbaNova University Center, Royal Institute of Technology, and Rehabilitation Medicine, Karolinska University Hospital, Stockholm, Sweden
    Pathobiology 72:203-12. 2005
    ....
  27. ncbi Neuronal fibrillogenesis: amyloid fibrils from primary neuronal cultures impair long-term memory in the crab Chasmagnathus
    Arturo Romano
    , , , Facultad de Ciencias Exactas y Naturales, Universidad de Buenos Aires, 1428, Argentina
    Behav Brain Res 147:73-82. 2003
    ..These results indicate that only naturally secreted fibrils, but not synthetic Abeta, clearly interfere with memory process...
  28. ncbi The endocytic pathway followed by the keratinocyte growth factor receptor
    Francesca Belleudi
    Dipartimento di Medicina Sperimentale e Patologia, Universita di Roma La Sapienza, Viale Regina Elena 324, 00161 Rome, Italy
    Histochem Cell Biol 118:1-10. 2002
    ..Pulse-chase experiments showed that the internalized KGFRs underwent degradation detectable at 1 h of endocytosis at 37 degrees C, indicating that KGFRs are functionally downregulated...
  29. ncbi Dicer expression and localization in post-mitotic neurons
    Christian Barbato
    EBRI European Brain Research Institute Fondazione EBRI Rita Levi Montalcini, Via del Fosso di Fiorano, 64 65, 00143 Roma, Italy
    Brain Res 1175:17-27. 2007
    ....
  30. ncbi Effects of extremely low frequency (50 Hz) magnetic field on morphological and biochemical properties of human keratinocytes
    Vanessa Manni
    Istituto di Neurobiologia e Medicina Molecolare CNR-Rome, Italy
    Bioelectromagnetics 23:298-305. 2002
    ..Our observations confirm the hypothesis that electromagnetic fields at 50 Hz may modify cell membrane morphology and interfere with initiation of the signal cascade pathway and cellular adhesion...
  31. ncbi Transglutaminase type II is a key element in the regulation of the anti-inflammatory response elicited by apoptotic cell engulfment
    Laura Falasca
    Laboratory of Electron Microscopy, National Institute for Infectious Diseases, National Institute for Infectious Diseases L Spallanzani, Italy
    J Immunol 174:7330-40. 2005
    ..These results help explain the autoimmune phenotype developed by these mice and suggest that TG2 is a key regulatory element of the anti-inflammatory features of apoptosis...
  32. ncbi Imaging the cell surface: argon sputtering to expose inner cell structures
    Gelsomina De Stasio
    University of Wisconsin Madison, Department of Physics and Synchrotron Radiation Center, Stoughton, Wisconsin 53589, USA
    Microsc Res Tech 63:115-21. 2004
    ..We conclude that the sputtering method is a new valuable tool for surface sensitive microscopies...