Massimo Imazio

..The described association can be important because interaction between ischemia and Brugada syndrome electrophysiological substrate could modulate individual susceptibility to life-threatening ventricular tachyarrhythmias...

..0), a lack of response to nonsteroidal anti-inflammatory drugs, and recurrent or incessant pericarditis (OR 10.0). A similar prognosis was found in patients with or without a history of known cancer...

..Treatment should focus on symptomatic relief, usually through the administration of non-steroidal anti-inflammatory drugs, and patients should be carefully evaluated and monitored for common complications of the disease...

..After a mean follow-up of 40 months, a higher recurrence rate was recorded in these patients (33.3% vs 14.1%; p = 0.02) as well as a nonsignificant trend to a higher rate of constrictive pericarditis...

..An early diagnosis allows timely surgical treatment. We report an unusual case of a main pulmonary artery aneurysm presenting with persistent non-productive cough and provide a review of the pertinent published data...

..We sought to investigate the safety and efficacy of a protocol for acute pericarditis triage and outpatient management of low-risk cases...

..This study was designed to investigate the prognostic value of cardiac troponin I (cTnI) in viral or idiopathic pericarditis...

..In developed countries the clinicians should rule out neoplastic, tuberculous, and purulent pericarditis, as well as pericarditis related to a systemic disease...

..In this article, the therapy of idiopathic and more common forms of infectious pericarditis (viral and bacterial) is reviewed...

..The aim of this work was to verify the safety and efficacy of colchicine as an adjunct to conventional therapy for the treatment of the first episode of acute pericarditis...

..Severe complications are rare, but the syndrome is responsible for hospital stay prolongation and readmissions. Female gender and pleura incision are risk factors for PPS...

..The aim of the Colchicine for the Prevention of the Post-Pericardiotomy Syndrome (COPPS) POAF substudy was to test the efficacy and safety of colchicine for the prevention of POAF after cardiac surgery...

..46 to 23.99, p <0.001) was associated with an increased risk for recurrence. After a mean follow-up of 72 months (range 48 to 108), a similar rate of complications was found in patients with or without recurrences...

..On this basis, we realized a substudy of the COPPS trial to assess the efficacy and safety of colchicine for the prevention of postoperative pericardial and pleural effusions...

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..e. pericardial window) should be considered whenever fluid re-accumulates (especially with tamponade), becomes loculated, or biopsy material is required...

..In this article, the therapy of more common forms of noninfectious pericarditis (pericarditis in systemic autoimmune diseases and neoplastic pericardial disease), pericardial effusion, and constrictive pericarditis is reviewed...

..A preliminary clinical trial has shown that colchicine may be considered not only for the treatment of postpericardiotomy syndrome (PPS), but also for its primary prevention...

..Colchicine is generally contraindicated during pregnancy, except in women with familial Mediterranean fever. These pregnancies should be followed by a dedicated multidisciplinary teams...

..However, the use of the drug is not based on any strong evidence obtained from clinical trials, and no randomized placebo-controlled trial is available to guide the management of acute pericarditis...

..The aim of the present article is to assess the relationship between clinical features at presentation and specific causes or complications...

..The aim of this work was to compare side effects, recurrences and other complications, and hospitalizations of a low- versus high-dose regimen of prednisone for recurrent pericarditis...

..This study is sought to investigate the prevalence and clinical significance of ANA in IRP...

..Few data have been reported on the diagnostic accuracy of Duke criteria in IVDUs with or without HIV infection, and a comparison of these two populations is lacking...

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..Early post-AMI pericarditis remains a marker of larger infarct size but without independent prognostic significance...

..The aim of this study is to evaluate the risk of CP after acute pericarditis in a prospective cohort study with long-term follow-up...

..Immunosuppressive drugs and steroid sparing agents might be used, but it should be acknowledged that only weak evidence-based data support their use...

..The aim of the COlchicine for the Prevention of the Post-pericardiotomy Syndrome (COPPS) trial is to test the efficacy and safety of colchicine for the primary prevention of the PPS...

..Corticosteroid use should be restricted, and low-to-medium doses (i.e., prednisone 0.2-0.5 mg/kg/day) should be preferred. Colchicine 0.5-1.2 mg/day is effective for reducing recurrences...

..Emerging data indicate that management can be tailored to the individual patient and, although the optimal duration of treatment is not clearly established, some recommendations can be formulated to guide management and follow-up...

..This paper also reviews specific dosing and precautions for the clinical use...

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..Moreover, some authors recommend the use of the drug at the first recurrence, whereas others propose to consider the drug only after failure of conventional therapies for the second or subsequent recurrence...

..Recurrence is the most common complication of pericarditis, affecting 10% to 50% of patients. Objective: To evaluate the efficacy and safety of colchicine for the secondary prevention of recurrent pericarditis...

..The aim of this study was to evaluate an alternative clinical approach by which echocardiographic screening is limited to patients with a clinical suspicion of heart disease...

..Invasive procedures should be limited mainly to patients in whom therapeutic intervention is necessary...

..Nevertheless, available data suggest a beneficial profile for colchicine and open a new therapeutic strategy for prevention of PPS...

..In order to provide an evidence-based clinical approach to management, we performed a systematic review of all publications on acute and recurrent pericarditis focusing on recent clinical trials...

..Therapeutic choices should take into account of the overall good outcome of these patients, including less toxic agents...

..Unfortunately, few data have been published on myopericarditis, the paper reviews current available evidence on the presentation, management, and prognosis of myopericarditis...

..The radial approach is not only safe but it enables faster patient mobilisation and seems also useful in reducing management costs with a hospital stay that can be reduced to 6 h in low-risk cases...

..Recurrence is the most common complication of pericarditis,affecting 10% to 50% of patients...

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..The background, rationale, aims and expected results of the registry are reviewed...

..e., pregnancy and systemic autoimmune diseases). Recurrences are the most common complication, but the overall prognosis is related to the etiology, usually benign in idiopathic pericarditis...

..Illicit drugs such as cocaine, and methadone can induce acquired long QT syndrome...

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..We report the results of a 2-year multicenter prospective survey that investigated new trends in the epidemiology, microbiological and clinical features and the prognosis of IE...

..The safety profile seems superior to other drugs such as corticosteroids and immunosuppressive drugs...

..goodfellowii sp. nov. Both cases were identified using 16S rRNA gene sequencing. Review of the English literature revealed only two other cases of Leptotrichia sp. endocarditis...

..This condition should immediately lead to cardiac surgery. Although pericardiectomy is the only treatment for permanent constriction, this procedure is contraindicated when extensive myocardial fibrosis and/or atrophy are demonstrated...

..This is also due to reluctance to perform BLS, especially mouth-to-mouth ventilation without barrier devices in victims who are unknown to the rescuer (either layperson or healthcare provider)...

..Indications for surgical intervention are different and mortality is increased. Newer antifungal treatment options are increasingly used. Large, multi-center studies are needed to help better define Candida IE...

..0% vs 50.6%, p=0.022; NNT= 4.0). No serious adverse effects were observed, while corticosteroids were an independent risk factor for further recurrences (OR 2.89)...

..The goal of the present study was to assess whether thoracic aorta calcification is associated with an increased risk of cardiovascular events and death in patients with stable angina pectoris...