Research Topics
Genomes and Genes | Anna CorcioneSummaryAffiliation: G. Gaslini Institute Country: Italy Publications
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Detail Information
Publications
CX3CR1 is expressed by human B lymphocytes and mediates [corrected] CX3CL1 driven chemotaxis of tonsil centrocytesAnna Corcione
Laboratory of Oncology, IRCCS G Gaslini, Genova, Italy
PLoS ONE 4:e8485. 2009....- Phenotypic and functional characterization of switch memory B cells from patients with oligoarticular juvenile idiopathic arthritisAnna Corcione
Laboratory of Oncology, IRCCS G Gaslini, Largo G Gaslini 5, Genoa, 16148, Italy
Arthritis Res Ther 11:R150. 2009..Here, we have characterized synovial fluid and tissue B-cell subsets in patients with oligoarticular juvenile idiopathic arthritis (JIA), an issue not addressed before in detail... - Human mesenchymal stem cells modulate B-cell functionsAnna Corcione
Laboratory of Oncology, G Gaslini Institute, Largo G Gaslini 5, 16148 Genova, Italy
Blood 107:367-72. 2006..These results further support the potential therapeutic use of hMSCs in immune-mediated disorders, including those in which B cells play a major role... - Chemokine receptor expression and function in childhood acute lymphoblastic leukemia of B-lineageAnna Corcione
Laboratory of Oncology, G Gaslini Institute, Largo G Gaslini 5, 16148 Genova, Italy
Leuk Res 30:365-72. 2006..Freshly isolated CCR7(+) early pre-B-ALL cells migrated to CCL19, whereas CCR7(+) pro-B- and pre-B-ALL cells were attracted by CCL19 only following culture with soluble recombinant CD40 ligand... - Recapitulation of B cell differentiation in the central nervous system of patients with multiple sclerosisAnna Corcione
Laboratory of Oncology, Scientific Direction, G Gaslini Institute, 16148 Genoa, Italy
Proc Natl Acad Sci U S A 101:11064-9. 2004..The presence of lymphotoxin-alpha, CXCL12, and CXCL13 in the CNS may provide favorable microenvironmental conditions for these events... - CCL19 and CXCL12 trigger in vitro chemotaxis of human mantle cell lymphoma B cellsAnna Corcione
Laboratory of Oncology, G Gaslini Institute, Largo G Gaslini 5, 16148 Genoa, Italy
Clin Cancer Res 10:964-71. 2004..Information on these issues may allow us to identify novel mechanisms of chemokine-driven tumor cell migration... - Chemotaxis of human tonsil B lymphocytes to CC chemokine receptor (CCR) 1, CCR2 and CCR4 ligands is restricted to non-germinal center cellsAnna Corcione
Laboratory of Oncology, G Gaslini Institute, Largo G Gaslini 5, 16148 Genova, Italy
Int Immunol 14:883-92. 2002..CCR1, CCR2 and CCR4 were detected by flow cytometry on non-GC (i.e. naive and memory) B cells, whereas they were absent (CCR1 and CCR2) or poorly expressed (CCR4) on GC B cells... - CCL3 (MIP-1alpha) induces in vitro migration of GM-CSF-primed human neutrophils via CCR5-dependent activation of ERK 1/2Luciano Ottonello
Laboratory of Phagocyte Physiopathology and Inflammation, Department of Internal Medicine, University of Genoa, G Gaslini Institute, Genoa, Italy
Cell Signal 17:355-63. 2005..This suggests that by activating ERK-1, GM-CSF renders neutrophils rapidly responsive to CCL3 stimulation throughout CCR5 which is constitutively expressed on the cell surface... - B-cell differentiation in the CNS of patients with multiple sclerosisAnna Corcione
Laboratory of Oncology, Department of Experimental and Laboratory Medicine, Scientific G. Gaslini Institute, Genoa, Italy
Autoimmun Rev 4:549-54. 2005..Thus, B cells are likely to expand and mature inside the CNS, giving rise to ASC, which may play an effector role in the pathogenesis of MS... - Changes in cytokine profile pre- and post-immunosuppression in acquired aplastic anemiaCarlo Dufour
Haematology Unit, G Gaslini Children s Hospital, Genoa, Italy
Haematologica 94:1743-7. 2009.... - Human Fanconi A cells are susceptible to TRAIL-induced apoptosisSimona Pigullo
Haematology Unit, Department of Paediatric Haemato Oncology, G Gaslini Children s Hospital, Genoa, Italy
Br J Haematol 136:315-8. 2007..This effect involved poly(ADP-ribose) polymerase-1 cleavage and caspase-8 activation... - TNF-alpha and IFN-gamma are overexpressed in the bone marrow of Fanconi anemia patients and TNF-alpha suppresses erythropoiesis in vitroCarlo Dufour
Hematology Unit, Department of Pediatric Hematology Oncology, G Gaslini Children s Hospital, Largo G Gaslini 5, 16147 Genoa, Italy
Blood 102:2053-9. 2003..This indicates that FA subjects have a marrow TNF-alpha activity that inhibits erythropoiesis in vitro. TNF-alpha has a relevant role in the pathogenesis of erythroid failure in FA patients... - The interleukin-12 and interleukin-12 receptor system in normal and transformed human B lymphocytesIrma Airoldi
Laboratory of Oncology, G Gaslini Institute, Largo G Gaslini 5, 16148 Genoa, Italy
Haematologica 87:434-42. 2002..IL-12 also activates human B-cells through the IL-12 receptor (IL-12R) complex. Here we review the expression and function of IL-12 and IL-12R in human B-cells and in their malignant counterparts... - Mechanisms of the adaptive immune response inside the central nervous system during inflammatory and autoimmune diseasesEnrico Pedemonte
Neuroimmunology Unit, Department of Neurosciences, Ophthalmology and Genetics, University of Genoa, Italy
Pharmacol Ther 111:555-66. 2006....