Enrico de Divitiis

..CONCLUSION: The endoscopic surgical route should be tailored to different sellar lesions, and some modifications of the procedure are recommended in selected cases...

..The extended transnasal approach allows early decompression of the optic canals, obviates the need for brain retraction, and reduces neurovascular manipulation...

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..Whether or not the transsphenoidal approach should be performed with the use of the microscope or the endoscope is finally discussed...

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..We describe the surgical technique for the purely endoscopic endonasal variant of the extended transsphenoidal "low route" to tuberculum sellae meningiomas...

..Epidermoid tumors, especially those located on the CPA, resulting from their avascular and noninfiltrative nature, appear particularly suited to being treated using an endoscopic approach...

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..The extended endonasal transsphenoidal route, under either microscopic or endoscopic visualization, has only recently been proposed as a viable surgical technique for the management of such tumors...

..Effective reconstruction of large skull base defects is a major concern in such extended approaches and remains challenging...

..The approach could be proposed as an alternative to the standard microsurgical transmaxillary-transantral route...

..This study aims to provide neurosurgeons with new data concerning direct endoscopic measurements and precise anatomical topography features of the pterygopalatine fossa...

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..The aim of this study is to define the pathological features, proliferation indexes, growth factors and hormone receptor expression in predicting the meningioma recurrence...

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..This study defines the indications, results, and limits of lateral orbitotomy coupled with resection of the sphenoid wing for removing lateral sphenoid wing meningiomas with intraorbital extension...

..In addition, they typically involve large intraoperative CSF leaks, which necessitate precise and effective dural closure...

..The procedure ends with the reconstruction of the sella and removal of the endoscope from the nostril, without any postoperative nasal packing...

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..Knowledge of these could be useful in decreasing morbidity and mortality during surgery in this region, these approaches being reserved to experienced transsphenoidal surgeons only...

..When used in combination, the collagen fleece enhances the sealing and tissue regeneration properties of the fibrin sealant, thus reducing the incidence of postoperative CSF leaks, obviating the need for a lumbar drain placement...

..This study describes the use of a novel collagen-based dural substitute in endoscopic endonasal transsphenoidal surgery...

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..Some minor expedients can be useful for the reconstruction, and the ideal material for the repair should be chosen...

..The recent advent of the endoscope in this specific field and the development of further possibilities and instrumentation has contributed to a new renaissance of this old treatment modality...

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..Considerable experience on cadavers should have already been obtained with the endoscope prior to any application in the operating room...

..The aim of this study is to evaluate the rate of infectious complications post endoscopic transspheinodal neurosurgery in patients receiving a new antibiotic chemoprophylaxis regimen...

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..The current possibilities of transsphenoidal endoscopy, with its related advantages and limitations, are presented...

..A series of 25 patients treated by endoscopic technique was analyzed, and the results were compared with those of 14 studies reporting patients treated by shunting...

..The case outlines that unilateral papilledema offers little information concerning tumor localization, and may represent a 'false' localizing sign...

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..The three main chapters of neuroendoscopy (transventricular, endonasal transphenoidal and endoscope-assisted microsurgery) are reviewed, concerning operative instruments, surgical procedures, main indications and results...

..5% and 9%, respectively. Overall success rate based on the patient questionnaire was 91% in Group 1 and 76% in Group 2. The authors conclude that the ligamentum flavum preservation technique is helpful in achieving good long-term results...