Salvatore Pece

Summary

Affiliation: European Institute of Oncology
Country: Italy

Publications

  1. ncbi Biological and molecular heterogeneity of breast cancers correlates with their cancer stem cell content
    Salvatore Pece
    IFOM, Fondazione Istituto FIRC di Oncologia Molecolare, Via Adamello 16, 20139 Milan, Italy
    Cell 140:62-73. 2010
  2. ncbi Alterations of the Notch pathway in lung cancer
    Britta Westhoff
    IFOM, Fondazione Istituto FIRC di Oncologia Molecolare, Milan, Italy
    Proc Natl Acad Sci U S A 106:22293-8. 2009
  3. ncbi NUMB-ing down cancer by more than just a NOTCH
    Salvatore Pece
    Fondazione Istituto FIRC di Oncologia Molecolare, Via Adamello 16, 20139, Milan, Italy
    Biochim Biophys Acta 1815:26-43. 2011
  4. ncbi NUMB controls p53 tumour suppressor activity
    Ivan N Colaluca
    IFOM, the FIRC Institute for Molecular Oncology Foundation, Via Adamello 16, 20139, Milan, Italy
    Nature 451:76-80. 2008

Collaborators

Detail Information

Publications4

  1. ncbi Biological and molecular heterogeneity of breast cancers correlates with their cancer stem cell content
    Salvatore Pece
    IFOM, Fondazione Istituto FIRC di Oncologia Molecolare, Via Adamello 16, 20139 Milan, Italy
    Cell 140:62-73. 2010
    ..Our data support the notion that the heterogeneous phenotypical and molecular traits of human breast cancers are a function of their CSC content...
  2. ncbi Alterations of the Notch pathway in lung cancer
    Britta Westhoff
    IFOM, Fondazione Istituto FIRC di Oncologia Molecolare, Milan, Italy
    Proc Natl Acad Sci U S A 106:22293-8. 2009
    ..Our results show that the deregulation of the Notch pathway is a relatively frequent event in NSCLCs and suggest that it might represent a possible target for molecular therapies in these tumors...
  3. ncbi NUMB-ing down cancer by more than just a NOTCH
    Salvatore Pece
    Fondazione Istituto FIRC di Oncologia Molecolare, Via Adamello 16, 20139, Milan, Italy
    Biochim Biophys Acta 1815:26-43. 2011
    ..Finally, we will discuss the role of Numb in the maintenance of the normal stem cell compartment, as a starting point to interpret the tumor suppressor function of Numb in the context of the cancer stem cell hypothesis...
  4. ncbi NUMB controls p53 tumour suppressor activity
    Ivan N Colaluca
    IFOM, the FIRC Institute for Molecular Oncology Foundation, Via Adamello 16, 20139, Milan, Italy
    Nature 451:76-80. 2008
    ..Biologically, this results in an aggressive tumour phenotype, as witnessed by findings that NUMB-defective breast tumours display poor prognosis. Our results uncover a previously unknown tumour suppressor circuitry...