Research Topics
| A F CiceroSummaryCountry: Italy Publications
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Publications
Serum lipopotein (a) levels in a large sample of subjects affected by familial combined hyperlipoproteinaemia and in general populationArrigo F G Cicero
Atherosclerosis Study Center G Descovich, Clinical Medicine and Applied Biotechnologies, Dept D Campanacci, University of Bologna, Italy
J Cardiovasc Risk 10:149-51. 2003..Serum lipoprotein (a) [Lp(a)] is a lipidic parameter, strictly under genetic control. Lp(a) levels vary in different dyslipidaemias according to the underlying disease...
Rice bran oil and gamma-oryzanol in the treatment of hyperlipoproteinaemias and other conditionsA F Cicero
Atherosclerosis and Dysmetabolic Disease Study Center G Descovich, Clinical Medicine and Applied Biotechnology Dept D Campanacci, University of Bologna, Italy
Phytother Res 15:277-89. 2001..This paper reviews the available data on the pharmacology and toxicology of rice bran oil and its main components with particular attention to those studies relating to plasma lipid altering effects...
[Cardiovascular risk factors in severely ill psychiatric patients]Arrigo F G Cicero
Centro per lo studio dell aterosclerosi e delle malattie dismetaboliche GC Descovichi, Ospedale Sant Orsola Malpighi Bologna
Epidemiol Prev 27:40-3. 2003..Thus, we find unethical do not treat hypertension, dyslipidemia and diabetes in severe psychiatric patients...
Effects of a new soy/beta-sitosterol supplement on plasma lipids in moderately hypercholesterolemic subjectsArrigo F G Cicero
Atherosclerosis and Dysmetabolic Disease Study Center G Descovich, Clinical Medicine and Applied Biotechnologies D Campanacci, University of Bologna, Italy
J Am Diet Assoc 102:1807-11. 2002..According to this recommends, low doses of soy protein added in b-sitosterol seems to be a practical and safe alternative for patients seeking modest reductions in LDL-C (< 15%)...
Panax notoginseng (Burk.) effects on fibrinogen and lipid plasma level in rats fed on a high-fat dietA F G Cicero
Athensclensis Study Center, G Descovich, University of Bologna, Italy
Phytother Res 17:174-8. 2003..Besides a moderate, non dose-related decrease in the plasma lipid levels, P. notoginseng appeared to induce a significant reduction in the rat fibrinogenaemia...
The realization of a project aimed at reducing the plasmatic lipid level in a large Italian population improves the mean calcium daily intake: the Brisighella StudyA Gaddi
Atherosclerosis and Metabolic Diseases Study Centre G Descovich, Department of Internal Medicine and Applied Biotechnology, University of Bologna, Italy
Eur J Clin Nutr 55:97-106. 2001..Evaluation of the impact of a coronary heart disease prevention program on calcium, magnesium, phosphorus and vitamin D dietary intake in respect of recommended daily allowances in a large Italian rural population...
Metalloproteinase-2 and -9 in diabetic and nondiabetic subjects during acute coronary syndromesGiuseppe Derosa
Department of Internal Medicine and Therapeutics, University of Pavia, Fondazione IRCCS Policlinico S Matteo, Pavia, Italy
Endothelium 14:45-51. 2007..MMP-9, TIMP-1, and TIMP-2 plasma levels were increased in diabetic patients with ACSs, which may reflect abnormal extracellular matrix metabolism in diabetes during acute event...
Interaction between serum cholesterol levels and the renin-angiotensin system on the new onset of arterial hypertension in subjects with high-normal blood pressureClaudio Borghi
Department of Internal Medicine, University of Bologna, Bologna, Italy
J Hypertens 25:2051-7. 2007..To investigate the possible interactions between serum cholesterol levels and the renin-angiotensin system on the development of stable hypertension in subjects with high-normal blood pressure (BP)...
Antihyperlipidaemic effect of a Monascus purpureus brand dietary supplement on a large sample of subjects at low risk for cardiovascular disease: a pilot studyArrigo F G Cicero
Department of Internal Medicine and Applied Biotechnology, Atherosclerosis and Metabolic Diseases Study Centre G Descovich, University of Bologna, S Orsola Malpighi University Hospital Via Massarenti, 9 40138 Bologna, Italy
Complement Ther Med 13:273-8. 2005....
Changes in LDL fatty acid composition as a response to olive oil treatment are inversely related to lipid oxidative damage: The EUROLIVE studyArrigo F G Cicero
GC Descovich Atherosclerosis and Metabolic Disease Research Unit, Internal Medicine, Aging and Kidney Diseases Dept, University of Bologna, Via Massarenti, 9, 40138 Bologna, Italy
J Am Coll Nutr 27:314-20. 2008..The aim of our study was to assess the changes in the fatty acid composition of low density lipoproteins (LDL) after sustained consumption of olive oil at real-life doses (25 mL/day) and their relationship with lipid oxidative damage...
Comparison of the effects of telmisartan and nifedipine gastrointestinal therapeutic system on blood pressure control, glucose metabolism, and the lipid profile in patients with type 2 diabetes mellitus and mild hypertension: a 12-month, randomized, doublGiuseppe Derosa
Department of Internal Medicine and Therapeutics, University of Pavia, Pavia, Italy
Clin Ther 26:1228-36. 2004..Angiotensin receptor blockers (ARBs) provide effective blood pressure control. Whereas none of the ARBs appear to affect glucose homeostasis, some ARBs have been associated with a decrease in cholesterolemia...
Effects of a new low dose soy protein/beta-sitosterol association on plasma lipid levels and oxidationArrigo F G Cicero
Atherosclerosis and Metabolic Diseases Study Centre G Descovich, Clinical Medicine and Applied Biotechnology, Dept D Campanacci, S Orsola Malpighi University Hospital, Via Massarenti, 9, 40138 Bologna, Italy
Eur J Nutr 43:319-22. 2004..High doses of soy protein are able to decrease plasma cholesterolemia significantly, but they unbalance daily protein intake and strongly modify nutritional habits in patients...
Metabolic effects of pioglitazone and rosiglitazone in patients with diabetes and metabolic syndrome treated with glimepiride: a twelve-month, multicenter, double-blind, randomized, controlled, parallel-group trialGiuseppe Derosa
Department of Internal Medicine and Therapeutics, University of Pavia, Piazzale C Golgi 2, 27100 Pavia, Italy
Clin Ther 26:744-54. 2004..Glimepiride is approved as monotherapy and in combination with metformin or with insulin, whereas the combination of glimepiride with other antihyperglycemic drugs is under investigation...
Eulipidemic effects of berberine administered alone or in combination with other natural cholesterol-lowering agents. A single-blind clinical investigationArrigo F G Cicero
G Descovich Atherosclerosis and Dysmetabolic Disease Research Center, D Campanacci Clinical Medicine and Applied Biotechnology Department, University of Bologna, Bologna, Italy
Arzneimittelforschung 57:26-30. 2007....
Telmisartan and irbesartan therapy in type 2 diabetic patients treated with rosiglitazone: effects on insulin-resistance, leptin and tumor necrosis factor-alphaGiuseppe Derosa
Department of Internal Medicine and Therapeutics, University of Pavia, Pavia, Italy
Hypertens Res 29:849-56. 2006..These observed metabolic effects of different angiotensin type 1 receptor blockers could be relevant when choosing a therapy to correct metabolic derangement of patients affected by metabolic syndrome and diabetes...
Asymptomatic massive hypertriglyceridemia in an octogenarianArrigo F G Cicero
Atherosclerosis and Metabolism Diseases Study Centre GC Descovich, Clinical Medicine and Applied Biotechnology Department D Campanacci, University of Bologna, Italy
Med Princ Pract 12:51-3. 2003..To report the case of an 85-year-old man with asymptomatic massive hypertriglyceridemia (MHTG)...
Blood pressure control and inflammatory markers in type 2 diabetic patients treated with pioglitazone or rosiglitazone and metforminGiuseppe Derosa
Department of Internal Medicine and Therapeutics, University of Pavia, Fondazione IRCCS Policlinico S Matteo, Pavia, Italy
Hypertens Res 30:387-94. 2007....
Metabolic and antihypertensive effects of moxonidine and moxonidine plus irbesartan in patients with type 2 diabetes mellitus and mild hypertension: a sequential, randomized, double-blind clinical trialGiuseppe Derosa
Department o f Internal Medicine and Therapeutics, University of Pavia, Fondazione IRCCS Policlinico S Matteo, Pavia, Italy
Clin Ther 29:602-10. 2007..The autonomic nervous system plays an important part in the homeostasis of blood pressure (BP), and sympathetic overactivity may contribute to metabolic conditions such as glycemic intolerance or insulin resistance...
Cerebrovascular disease in Italy and Europe: it is necessary to prevent a 'pandemia'Antonio Gaddi
Atherosclerosis and Dysmetabolic Disease Study Centre G Descovich, University of Bologna, Italy
J Cardiovasc Risk 9:143-5. 2002..It is plausible that the application of a suitable early prevention of the cerebrovascular pathology could bring to a more late slatentisation and less serious demonstrations of Alzheimer's disease, when this is destined to develop...
Vascular remodeling and prothrombotic markers in subjects affected by familial combined hyperlipidemia and/or metabolic syndrome in primary prevention for cardiovascular diseaseArrigo F G Cicero
GC Descovich Atherosclerosis and Metabolic Disease Research Unit, D Campanacci Clinical Medicine and Applied Biotechnology Department, Alma Mater Studiorum University of Bologna, Bologna, Italy
Endothelium 14:193-8. 2007..However, the superposition of MS on FCH further increases the plasma level of these parameters. The prognostic value of this observation has to be evaluated...
Comparison between metalloproteinases-2 and -9 in healthy subjects, diabetics, and subjects with acute coronary syndromeGiuseppe Derosa
Department of Internal Medicine and Therapeutics, University of Pavia, Fondazione IRCCS Policlinico S Matteo, Pavia, Italy
Heart Vessels 22:361-70. 2007..In conclusion, MMP-2, MMP-9, TIMP-1, and TIMP-2 plasma levels were higher in diabetic, ACS, and DACS patients, which may reflect abnormal extracellular matrix metabolism in diabetes and in acute coronary syndrome...
Persistence on treatment and blood pressure control with different first-line antihypertensive treatments: a prospective evaluationMaria Grazia Prandin
D Campanacci Clinical Medicine and Applied Biotechnology Department, Alma Mater Studiorum, University of Bologna, Italy
Clin Exp Hypertens 29:553-62. 2007..46.6%). Systolic and diastolic BP decreased more in patients treated with ARBs (-11.2/-5.8 mmHg), ACE inhibitors (-10.5/-5.1 mmHg), and CCBs (-8.5/-4.6 mmHg) when compared to beta-blockers (-4.0/-2.3 mmHg) and diuretics (-2.3/-2.1 mmHg)...
Fixed combination of zofenopril plus hydrochlorothiazide in the management of hypertension: a review of available dataClaudio Borghi
Hypertension Research Center, D Campanacci Clinical Medicine and Applied Biotechnology Department, Alma Mater Studiorum, University of Bologna, Italy
Vasc Health Risk Manag 2:341-9. 2006....
Synergistic effect of doxazosin and acarbose in improving metabolic control in patients with impaired glucose toleranceGiuseppe Derosa
Department of Internal Medicine and Therapeutics, University of Pavia, Pavia, Italy
Clin Drug Investig 26:529-39. 2006..The aim of this study was to evaluate if the expected improvement in glucose and lipid metabolism obtainable with doxazosin is or is not synergistic with standard antihyperglycaemic treatment using the alpha-glucosidase inhibitor acarbose...
A randomized, double-blind, controlled, parallel-group comparison of perindopril and candesartan in hypertensive patients with type 2 diabetes mellitusGiuseppe Derosa
Department of Internal Medicine and Therapeutics, University of Pavia, IRCCS Policlinico S Matteo, Pavia, Italy
Clin Ther 25:2006-21. 2003....
Effect of oral chronic isoflavones supplementation on male rat sexual performances and sexual hormone plasma levelsArrigo F G Cicero
Biomedical Sciences Department, Pharmacology Section, University of Modena and Reggio nell emilia, Modena, Italy
Phytother Res 18:849-52. 2004..No significant difference has been observed as regards FSH, progesterone, androstenedione plasma levels, either between groups or between baseline and study end. Slight differences were found regards LH and testosterone plasma level...
Antithrombotic effects of rosiglitazone-metformin versus glimepiride-metformin combination therapy in patients with type 2 diabetes mellitus and metabolic syndromeGiuseppe Derosa
Department of Internal Medicine and Therapeutics, University of Pavia, Italy
Pharmacotherapy 25:637-45. 2005....
A comparison of the effects of pioglitazone and rosiglitazone combined with glimepiride on prothrombotic state in type 2 diabetic patients with the metabolic syndromeGiuseppe Derosa
Department of Internal Medicine and Therapeutics, University of Pavia, P le C Golgi, 2 27100 Pavia, Italy
Diabetes Res Clin Pract 69:5-13. 2005..To compare the effects of glimepiride plus pioglitazone or plus rosiglitazone in diabetic patients with the metabolic syndrome on coagulation and fibrinolysis parameters...
The effect of L-carnitine on plasma lipoprotein(a) levels in hypercholesterolemic patients with type 2 diabetes mellitusGiuseppe Derosa
Department of Internal Medicine and Therapeutics, University of Pavia, Pavia, Italy
Clin Ther 25:1429-39. 2003..A previous study has demonstrated that L-carnitine reduces plasma lipoprotein(a) (Lp[a]) levels in patients with hypercholesterolemia...
Hypercholesterolemia underdiagnosis and undertreatment in psychiatric patients in ItalyArrigo F G Cicero
Eur J Epidemiol 18:373-4. 2003
Matrix metalloproteinase-2, -9, and tissue inhibitor of metalloproteinase-1 in patients with hypertensionGiuseppe Derosa
Department of Internal Medicine and Therapeutics, University of Pavia, Pavia, Italy
Endothelium 13:227-31. 2006..0001) and for TIMP-1 (p < .0001) in hypertensive patients. Plasma levels and activities of MMP-2, MMP-9, and TIMP-1 are increased in hypertensive patients, which may reflect abnormal ECM metabolism...
Effects of 1 year of treatment with pioglitazone or rosiglitazone added to glimepiride on lipoprotein (a) and homocysteine concentrations in patients with type 2 diabetes mellitus and metabolic syndrome: a multicenter, randomized, double-blind, controlledGiuseppe Derosa
Department of Internal Medicine and Therapeutics, University of Pavia, Pavia, Italy
Clin Ther 28:679-88. 2006....
Prospects for the development of novel anti-hyperlipidemic drugsGiuseppe Derosa
Department of Internal Medicine and Therapeutics, University of Pavia, Italy
Curr Opin Investig Drugs 7:826-33. 2006....
Long-term effects of glimepiride or rosiglitazone in combination with metformin on blood pressure control in type 2 diabetic patients affected by the metabolic syndrome: a 12-month, double-blind, randomized clinical trialGiuseppe Derosa
Department of Internal Medicine and Therapeutics, University of Pavia, Pavia, Italy
Clin Ther 27:1383-91. 2005..Based on a literature search, few direct comparisons of different antihyperglycemic treatments on blood pressure have been reported...
