Research Topics
| D ChiumelloSummaryCountry: Italy Publications
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Publications
Lung opening and closing during ventilation of acute respiratory distress syndromePietro Caironi
Dipartimento di Anestesiologia, Fondazione Istituto di Ricovero e Cura a Carattere Scientifico Ospedale Maggiore Policlinico, Universita degli Studi di Milano, Milan, Italy
Am J Respir Crit Care Med 181:578-86. 2010....- Bench-to-bedside review: chest wall elastance in acute lung injury/acute respiratory distress syndrome patientsLuciano Gattinoni
Institute of Anesthesia and Critical Care, University of Milan, Policlinico IRCCS Hospital, Milan, Italy
Crit Care 8:350-5. 2004..It is always important in the most critically ill patients to assess the intra-abdominal pressure and the chest wall elastance... - Chest wall mechanics during pressure support ventilationAndrea Aliverti
Dipartimento di Bioingegneria, Politecnico di Milano, Milano, Italy
Crit Care 10:R54. 2006.... - Effects of thoraco-pelvic supports during prone position in patients with acute lung injury/acute respiratory distress syndrome: a physiological studyDavide Chiumello
Dipartimento di Anestesia e Rianimazione, Fondazione IRCCS-Ospedale Maggiore Policlinico, Mangiagalli, Regina Elena, Via F, Sforza 35, 20122 Milan, Italy
Crit Care 10:R87. 2006..Consequently, we stopped their use in clinical practice... - Effect of different cycling-off criteria and positive end-expiratory pressure during pressure support ventilation in patients with chronic obstructive pulmonary diseaseDavide Chiumello
Dipartimento di Anestesia e Rianimazione, Fondazione Istituto di Ricovero e Cura a Carattere Scientifico Ospedale Maggiore Policlinico, Mangiagalli, Regina Elena, Milan, Italy
Crit Care Med 35:2547-52. 2007..This study evaluated the effect of two different cycling-off criteria on breathing pattern, respiratory effort, and gas exchange in patients with chronic obstructive pulmonary disease... - Long-term outcomes in survivors of acute respiratory distress syndrome ventilated in supine or prone positionD Chiumello
Dipartimento di Anestesia, Rianimazione Intensiva e Subintensiva e Terapia del Dolore, Fondazione IRCCS Ca Granda Ospedale Maggiore Policlinico, Via Francesco Sforza 35, Milan, Italy
Intensive Care Med 38:221-9. 2012.... - A complication of amiodarone infusionDavide Chiumello
Istituto di Anestesia e Rianimazione, Universita di Milano, Ospedale Policlinico IRCCS, Milan, Italy
Eur J Emerg Med 11:102-4. 2004..We hypothesized that this intravascular mass was due to a deposition of the Amiodarone during the infusion in the central line.. - Respirator management of sepsis-related respiratory failureDavide Chiumello
U O Anestesia e Rianimazione, Dipartimento di Anestesia, Rianimazione Intensiva e Subintensiva e Terapia del Dolore, Fondazione IRCCS, Ospedale Maggiore Policlinico, Mangiagalli, Regina Elena di Milano, Via Francesco Sforza 35, 20122 Milano, Italy
Curr Infect Dis Rep 11:365-71. 2009..Inhaled nitric oxide, which is a pulmonary vasodilator with anti-inflammatory properties, is associated with limited improvement in oxygenation without improvement in survival... - Nitrogen washout/washin, helium dilution and computed tomography in the assessment of end expiratory lung volumeDavide Chiumello
Dipartimento di Anestesia, Rianimazione Intensiva e Subintensiva e Terapia del Dolore, Fondazione IRCCS Ospedale Maggiore Policlinico Mangiagalli Regina Elena, Via Francesco Sforza 35, 20122, Milano, Italy
Crit Care 12:R150. 2008..We compared the EELV measured by spiral computed tomography (CT) taken as gold standard with the lung volume measured with the modified nitrogen washout/washin and with the helium dilution technique... - Effect of a heated humidifier during continuous positive airway pressure delivered by a helmetDavide Chiumello
Unità Operativa di Anestesia e Rianimazione, Fondazione IRCCS Ospedale Maggiore Policlinico, Mangiagalli, Regina Elena, Via F, Sforza 35, 20122 Milan, Italy
Crit Care 12:R55. 2008..We evaluated the temperature and humidity of respiratory gases inside the helmet, with and without a heated humidifier, during continuous positive airway pressure (CPAP) delivered with a helmet... - Estimation of dead space fraction can be simplified in the acute respiratory distress syndromeDavide Chiumello
Dipartimento di Anestesia, Rianimazione e Terapia del Dolore, Fondazione IRCCS, Ca Granda Ospedale Maggiore Policlinico, Via F, Sforza 35, Milan, Italy
Crit Care 14:195. 2010.... - Noninvasive positive pressure ventilation delivered by helmet vs. standard face maskDavide Chiumello
Istituto di Anestesia e Rianimazione, Ospedale Maggiore Policlinico IRCCS, Universita degli Studi di Milano, Via Francesco Sforza 35, 20122 Milan, Italy
Intensive Care Med 29:1671-9. 2003..This bench and human study compared large and small helmets with face mask (FM) for delivery of noninvasive positive pressure ventilation... - A validation study of a new nasogastric polyfunctional catheterD Chiumello
Dipartimento di Anestesia, Rianimazione, Fondazione IRCCS Ca Granda, Ospedale Maggiore Policlinico, Milan, Italy
Intensive Care Med 37:791-5. 2011..We compared the Pes and IGP measured using this new device with those obtained with a standard balloon catheter taken as gold standard... - Non-invasive ventilation in postoperative patients: a systematic reviewD Chiumello
U O Anestesia e Rianimazione, Dipartimento di Anestesia, Rianimazione Intensiva e Subintensiva e Terapia del Dolore, Fondazione IRCCS Ca Granda Ospedale Maggiore Policlinico, Via Francesco Sforza 35, 20122 Milan, Italy
Intensive Care Med 37:918-29. 2011..Non-invasive ventilation (NIV), primarily applied in cardiogenic pulmonary edema, decompensated COPD and hypoxemic pulmonary failure, is nowadays also used in perioperative settings... - Year in Review in MINERVA ANESTESIOLOGICA, 2007. I Critical Care. Experimental and clinical studiesD Chiumello
Department of Anesthesia and Intensive Care, IRCCS Foundation, Ospedale Maggiore Policlinico, Mangiagalli Regina Elena, Milan, Italy
Minerva Anestesiol 74:35-40. 2008 - Effects of volume shift on the pressure-volume curve of the respiratory system in ALI/ARDS patientsD Chiumello
Department of Anesthesia and Intensive Care, IRCCS Foundation, Ospedale Maggiore Policlinico, Mangiagalli, Regina Elena, Milan, Italy
Minerva Anestesiol 73:109-18. 2007..Another possible confounding factor is the volume shift, primarily blood, out of the chest wall when the intrathoracic pressures rise. We set out to quantify the volume shift and investigate its mechanisms... - The effect of different volumes and temperatures of saline on the bladder pressure measurement in critically ill patientsDavide Chiumello
Dipartimento di Anestesia e Rianimazione, Fondazione IRCCS Ospedale Maggiore Policlinico, Mangiagalli, Regina Elena, Via F Sforza 35, 20122 Milan, Italy
Crit Care 11:R82. 2007..The aim of this study was to evaluate the effect of different volumes and temperatures of infused saline on bladder pressure measurements in comparison with gastric pressure... - In vitro and in vivo evaluation of a new active heat moisture exchangerDavide Chiumello
Institute of Anesthesia and Critical Care, University of Milan, Policlinico Hospital, IRCCS, Milan, Italy
Crit Care 8:R281-8. 2004..In this study we evaluated the efficiency, both in vitro and in vivo, of a new active HME (the Performer; StarMed, Mirandola, Italy) as compared with that of existing HMEs (Hygroster and Hygrobac; Mallinckrodt, Mirandola, Italy)... - Estimation of end-expiratory lung volume variations by optoelectronic plethysmographyR L Dellaca
Dipartimento di Bioingegneria Politecnico Di Milano and the Centro di Bioingegneria, Fond Don Gnocchi IRCCS, Politecnico di Milano, Milano, Italy
Crit Care Med 29:1807-11. 2001..To test the capability of optoelectronic plethysmography (OEP) to monitor positive end-expiratory pressure (PEEP)-induced changes of end-expiratory lung volume (EELV) changes in mechanically ventilated paralyzed patients... - Physical and biological triggers of ventilator-induced lung injury and its preventionL Gattinoni
Institute of Anaesthesia and Intensive Care, University of Milan, Policlinico Hospital, IRCCS, Milan, Italy
Eur Respir J Suppl 47:15s-25s. 2003.... - Different modes of assisted ventilation in patients with acute respiratory failureD Chiumello
Istituto di Anestesia e Rianimazione, Universita' degli Studi di Milano, Ospedale Policlinico-IRCCS, Italy
Eur Respir J 20:925-33. 2002..During assist control, tidal volume and peak inspiratory flow (set by the physician) are the main determinants of the patient/ventilator interaction... - [A rationale basis for airways conditioning: too wet or not too wet? ]P Severgnini
Dipartimento di Scienze Cliniche e Biologiche, Universita degli Studi dell Insubria, Varese, Italy
Minerva Anestesiol 69:297-301. 2003..We think that inspired AH must be equal to expired AH to maintain an airway hydric balance at least level. At last, the temperature of inspired gases, with active hot humidifiers, shouldn't exceed 32-34 degrees C... - Fulminant multiorgan failure due to varicella zoster virus and HHV6 in an immunocompetent adult patient, and anhepatiaU Maggi
U O Chirurgia Generale e Trapianti di Fegato, Fondazione IRCCS Cà Granda Ospedale Maggiore Policlinico Milano, Milano, Italy
Transplant Proc 43:1184-6. 2011.... - Non-invasive ventilation outside the Intensive Care Unit for acute respiratory failureD Chiumello
Operative Unit of Anesthesia and Resuscitation, Department of Anesthesia, Intensive and Subintensive Resuscitation and Pain Therapy, IRCCS Foundation, Polyclinic Mangiagalli Regina Elena, Milan, Italy
Minerva Anestesiol 75:459-66. 2009..This review presents and discusses the currently available data regarding NIV success outside the intensive care unit, the optimal ventilatory strategy, possible solutions to the mechanical problems and the minimum monitoring required... - Lung stress and strain during mechanical ventilation for acute respiratory distress syndromeDavide Chiumello
Dipartimento di Anestesia, Rianimazione, Intensiva e Subintensivae, Terapia del Dolore, Fondazione IRCCS, Ospedale Maggiore Policlinico Mangiagalli Regina Elena di Milano, Milan, Italy
Am J Respir Crit Care Med 178:346-55. 2008..Lung injury caused by a ventilator results from nonphysiologic lung stress (transpulmonary pressure) and strain (inflated volume to functional residual capacity ratio)... - Lung recruitment in patients with the acute respiratory distress syndromeLuciano Gattinoni
Istituto di Anestesiologia e Rianimazione, Fondazione Istituto di Ricovero e Cura a Carattere Scientifico, Ospedale Maggiore Policlinico, Mangiagalli, Regina Elena di Milano, Universita degli Studi di Milano, Milan, Italy
N Engl J Med 354:1775-86. 2006.... - Reduced tidal volumes and lung protective ventilatory strategies: where do we go from here?Luciano Gattinoni
Istituto di Anestesia e Rianimazione, Universita degli Studi di Milano, Ospedale Policlinico IRCCS, Milano, Italy
Curr Opin Crit Care 8:45-50. 2002..quot;Full" protective lung strategy was tested in only one study and in a limited number of patients. Several physiologic studies strongly suggest the advantages of the lung protective strategy... - Prolongation of antibiotic prophylaxis after clean and clean-contaminated surgery and surgical site infectionS De Chiara
Department of General Resuscitation, Institute of Anesthesia and Resuscitation University of Milan, Fondazione IRCCS, Ospedale Maggiore Policlinico, Mangiagalli and Regina Elena, Milan, Italy
Minerva Anestesiol 76:413-9. 2010..In this observational study, we evaluated the risk of surgical site infection (SSI) associated with the prolongation of AMP after clean and clean-contaminated surgery... - [The fluid balance in the critically ill patient]P Bruzzone
Istituto di Anestesia e Rianimazione, Ospedale Policlinico, IRCCS, Universita degli Studi di Milano, Milano, Italy
Minerva Anestesiol 70:431-6. 2004..Aim of this study was to prospectively evaluate the accuracy of the fluid balance compared to the body weight measured by a dedicated mattress (Hill-Rom)... - Acute respiratory distress syndrome, the critical care paradigm: what we learned and what we forgotLuciano Gattinoni
Istituto di Anestesia e Rianimazione, Universita degli Studi di Milano, Ospedale Policlinico IRCCS, Milano, Italy
Curr Opin Crit Care 10:272-8. 2004..Measurements of variables as transpulmonary pressure and end expiratory lung volume, for a rational setting of mechanical ventilation, should be introduced in routine clinical practice... - Pulmonary computed tomography and adult respiratory distress syndromeLuciano Gattinoni
Istituto de Anestesia e Rianimazione, Universita degli Studi di Milano, Ospedale Policlinico IRCCS, Italy
Swiss Med Wkly 135:169-74. 2005..In this brief review we will emphasize the most relevant new knowledge achieved using CT scanning and we will briefly discuss its clinical use in ARDS patients... - Relationship between gas exchange response to prone position and lung recruitability during acute respiratory failureAlessandro Protti
Dipartimento di Anestesiologia, Terapia Intensiva e Scienze Dermatologiche, Fondazione IRCCS Ospedale Maggiore Policlinico, Mangiagalli e Regina Elena di Milano, Universita degli Studi di Milano, Via F Sforza 35, 20122 Milan, Italy
Intensive Care Med 35:1011-7. 2009..To clarify whether the gas exchange response to prone position is associated with lung recruitability in mechanically ventilated patients with acute respiratory failure... - Case of exogenous lipoid pneumonia: steroid therapy and lung lavage with an emulsifierRiccarda Russo
Istituto di Anestesia e Rianimazione, Fondazione Instituto di Ricovero e Cura a Carattere Scientifico (IRCCS, Ospedale Maggiore Policlinico Mangiagalli e Regina Elena, Milano, Italy
Anesthesiology 104:197-8. 2006 - Total hepatectomy, recombinant activated factor VII and rescue liver transplantationP Cozzi
Department of Anesthesia and Intensive Care, Fondazione IRCCS Ca Granda, Ospedale Maggiore Policlinico, Milan, Italy
Minerva Anestesiol 76:550-3. 2010..In the case of an anhepatic phase complicated by severe bleeding that is unresponsiveness to several transfusions, a single administration of rFVIIa should be considered as a rescue therapy to control massive bleeding... - Physiologic rationale for ventilator setting in acute lung injury/acute respiratory distress syndrome patientsLuciano Gattinoni
Istituto di Anestesia e Rianimazione, Universita' degli Studi di Milano, Ospedale Policlinico-IRCCS, Milano, Italy
Crit Care Med 31:S300-4. 2003..CONCLUSIONS: The majority of physiologic, experimental, and clinical trial data converge on one simple concept: treat the lung gently... - Effect of different inspiratory rise time and cycling off criteria during pressure support ventilation in patients recovering from acute lung injuryDavide Chiumello
Istituto di Anestesia e Reanimazione, Universita' degli Studi Milano, Ospedale Policlinico-IRCSS, Milan, Italy
Crit Care Med 31:2604-10. 2003..Modifications of inspiratory rise time and cycling off criteria must be carefully adjusted during pressure support ventilation... - Decrease in PaCO2 with prone position is predictive of improved outcome in acute respiratory distress syndromeLuciano Gattinoni
Istituto di Anestesia e Rianimazione, Universita degli Studi di Milano, Ospedale Policlinico, Milan, Italy
Crit Care Med 31:2727-33. 2003..To determine whether gas exchange improvement in response to the prone position is associated with an improved outcome in acute lung injury (ALI)/acute respiratory distress syndrome (ARDS)... - Anatomical and functional intrapulmonary shunt in acute respiratory distress syndromeMassimo Cressoni
Istituto di Anestesiologia e Rianimazione, Universita degli Studi di Milano, Milan, Italy
Crit Care Med 36:669-75. 2008..Therefore, we aimed to assess the value of venous admixture (functional shunt) in estimating the fraction of nonaerated lung tissue (anatomical shunt compartment) and to describe their relationship... - Sigh in supine and prone position during acute respiratory distress syndromePaolo Pelosi
Dipartimento di Scienze Cliniche e Biologiche, , Ospedale di Circolo, Fondazione Macchi, Varese
Am J Respir Crit Care Med 167:521-7. 2003..82, p < 0.001). We conclude that adding a recruitment maneuver such as cyclical sighs during ventilation in the prone position may provide optimal lung recruitment in the early stage of ARDS... - Noninvasive positive pressure ventilation using a helmet in patients with acute exacerbation of chronic obstructive pulmonary disease: a feasibility studyMassimo Antonelli
Istituto di Anestesiologia e Rianimazione, Universita Cattolica del Sacro Cuore, Rome, Italy
Anesthesiology 100:16-24. 2004..Whether it is feasible to treat these patients with NPPV delivered by a helmet is not known... - Performance of heated wire humidifiers: an in vitro studyPaolo Pelosi
Department of Environment, Health, and Safety, University of Insubria Circolo and Fondazione Macchi Hospital, Varese, Italy
J Crit Care 22:258-64. 2007..We assessed the performance of heated wire humidifiers (HWHs), which should avoid water condensation in the circuit... - Is the helmet different than the face mask in delivering noninvasive ventilation?Davide Chiumello
Chest 129:1402-3. 2006 - Non-invasive ventilation delivered by conventional interfaces and helmet in the emergency departmentPaolo Pelosi
, Dipartimento di Scienze Cliniche e Biologiche, Azienda Ospedaliera Universitaria, Ospedale di Circolo e Fondazione Macchi, Varese, Italy
Eur J Emerg Med 10:79-86. 2003..We believe that the helmet can extend the application of non-invasive positive pressure ventilation in different categories of patients with respiratory failure... - Spontaneous breathing during mechanical ventilationDavide Chiumello
Crit Care Med 33:1170-1. 2005 - Prevalence of intra-abdominal hypertension in critically ill patients: a multicentre epidemiological studyManu L N G Malbrain
Medical Intensive Care Unit, ACZA Campus Stuivenberg, Lange Beeldekensstraat 267, 2060 Antwerp, Belgium. manu.malbrain@ skynet.be
Intensive Care Med 30:822-9. 2004..CONCLUSION: Although we found a quite high prevalence of IAH, no risk factors were reliably associated with IAH; consequently, to get valid information about IAH, IAP needs to be measured... - Incidence and prognosis of intraabdominal hypertension in a mixed population of critically ill patients: a multiple-center epidemiological studyManu L N G Malbrain
Intensive Care Unit Director, Medical Intensive Care Unit, Ziekenhuis Netwerk Antwerpen, Campus Stuivenberg, Lange Beeldekensstraat 267, B 2060 Antwerpen 6, Belgium
Crit Care Med 33:315-22. 2005....