Research Topics
| S BoniniSummaryAffiliation: Catholic University Country: Italy Publications
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Detail Information
Publications
Neurotrophic keratitisS Bonini
Laboratory of Ophthalmology, Interdisciplinary Center for Biomedical Research, University of Rome, Rome, Italy
Eye (Lond) 17:989-95. 2003..Future developments in the medical treatment including the administration of neuropeptide and growth factors are presented...
Vernal keratoconjunctivitisS Bonini
Interdisciplinary Center for Biomedical Research CIR, Laboratory of Ophthalmology, University of Rome, Campus Bio Medico, Rome, Italy
Eye (Lond) 18:345-51. 2004..A 2% solution of cyclosporine in olive oil or in castor oil should be considered as an alternative. The long-term prognosis of patients is generally good; however 6% of patients develop corneal damage, cataract, or glaucoma...
Allergic chronic inflammation of the ocular surface in vernal keratoconjunctivitisStefano Bonini
Interdisciplinary Center for Biomedical Research CIR Laboratory of Ophthalmology, University of Rome Campus Bio Medico, and G B Bietti Eye Foundation, Italy
Curr Opin Allergy Clin Immunol 3:381-7. 2003....
Upregulation of ICAM-1 expression in the conjunctiva of patients with chronic graft-versus-host diseaseS Aronni
Interdisciplinary Center for Biomedical Research (CIR, Laboratory of Ophthalmology, University of Roma Campus Bio-Medico, Roma, Italy
Eur J Ophthalmol 16:17-23. 2006..01, rho=0.982). CONCLUSIONS: Conjunctival ICAM-1 expression is increased in GVHD patients. The severity of the disease is associated with tear parameters, goblet cell decrease, and inflammatory markers, such as ICAM-1...
Systematic review and meta-analysis of randomised clinical trials on topical treatments for vernal keratoconjunctivitisF Mantelli
Department of Ophthalmology, University of Rome Campus Bio Medico, Via Emilio Longoni 83, 00155 Rome, Italy
Br J Ophthalmol 91:1656-61. 2007..The aim of this study was to assess the efficacy of currently available topical drugs for vernal keratoconjunctivitis (VKC) through a meta-analysis of randomised clinical trials (RCTs)...
Mimicking microbial 'education' of the immune system: a strategy to revert the epidemic trend of atopy and allergic asthma?P M Matricardi
DASRS, Pomezia Rome, Italy
Respir Res 1:129-32. 2000..Although such a strategy is far beyond our present potential, it may in principle revert the epidemic trend of atopy and allergic asthma without jeopardizing the fight against infectious diseases...
Nerve growth factor: an important molecule in allergic inflammation and tissue remodellingS Bonini
Institute of Experimental Medicine, CNR, University of Rome, Italy
Int Arch Allergy Immunol 118:159-62. 1999..Several studies provide evidence that nerve growth factor (NGF) has an expanding role in neuroimmune interactions...
Amniotic membrane transplantation associated with conjunctival peritomy in the management of Mooren's ulcer: a case reportA Lambiase
Interdisciplinary Center for Biomedical Research CIR, Laboratory of Ophthalmology, University of Roma Campus Bio Medico, Roma, Italy
Eur J Ophthalmol 15:274-6. 2005..To report the association of conjunctival peritomy with amniotic membrane transplantation (AMT) at the limbus with the exclusion of the central cornea in order to preserve visual function in one case of bilateral Mooren's ulcer...
Clinical application of nerve growth factor on human corneal ulcerA Lambiase
Interdisciplinary Center for Biomedical Research CIR, Laboratory of Ophthalmology, University of Rome Campus Bio Medico, G B Bietti Eye Foundation, Rome, Italy
Arch Ital Biol 141:141-8. 2003..These findings indicate that failure of cutaneous tissues to produce sufficient amounts of NGF might represent a prominent mechanism implicated in the clinical manifestation of ocular ulcers...
Atopic keratoconjunctivitisS Bonini
Institute of Neurobiology and Molecular Medicine, Italian National Research Council and San Raffaele H, Rome, Italy
Allergy 59:71-3. 2004..AKC and VKC may thus represent a model of atopy quite distinct from the classical type-1 hypersensitivity mechanism...
Nerve growth factor: neurotrophin or cytokine?S Bonini
Institute of Neurobiology and Molecular Medicine, Italian National Research Council INMM CNR, Rome, Italy
Int Arch Allergy Immunol 131:80-4. 2003..Data reviewed suggest, therefore, that NGF might also be viewed as a (Th2?) cytokine with a modulatory role in allergic inflammation and tissue remodeling...
Methodology for development of the Allergic Rhinitis and its Impact on Asthma guideline 2008 updateJ L Brozek
S C Epidemiologia, Italian National Cancer Institute Regina Elena, Rome, Italy
Allergy 63:38-46. 2008..The most prominent change is the application of the Grading of Recommendations Assessment, Development and Evaluation (GRADE) approach to compiling evidence, assessing the quality of evidence and grading of recommendations...
The future of microarray technology: networking the genome searchL Gatta
IRCCS San Raffaele, Research Center, Rome, Italy
Allergy 60:1219-26. 2005..Networks of excellence like GA(2)LEN may represent the best approach for teaching, cost reduction, data repositories, and functional studies implementation...
Rhinitis and asthma in athletes: an ARIA document in collaboration with GA2LENS Bonini
IRCCS San Raffale, Rome, Italy
Allergy 61:681-92. 2006....
Animal models of allergic and inflammatory conjunctivitisD A Groneberg
Department of Pediatric Pneumology and Immunology, , Humboldt-University Berlin, Germany
Allergy 58:1101-13. 2003..In the future, combined ocular, nasal and aerosolic challenges with allergens may provide a model of allergy that encompasses simultaneously the target organs eye, nose and airways with conjunctivitis, rhinitis and asthma...
Autologous fibrin-cultured limbal stem cells permanently restore the corneal surface of patients with total limbal stem cell deficiencyP Rama
Division of Ophthalmology, Ospedale S.S. Giovanni e Paolo, Venice, Italy
Transplantation 72:1478-85. 2001..The multicenter nature of this study and the handiness and ease of long-distance transportation of the fibrin-cultured epithelial sheets suggest that this technology can now be widely applied...
Allergy and infections: long-term improvement of vernal keratoconjunctivitis following viral conjunctivitisR Sgrulletta
Interdisciplinary Center for Biomedical Research (CIR, Laboratory of Ophthalmology, University of Roma 'Campus Bio-Medico' and G.B. Bietti Eye Foundation, IRCCS, Roma--Italy
Eur J Ophthalmol 16:470-3. 2006..CONCLUSIONS: In this case, the viral infection seemed to induce a clinical recovery of allergic disease, suggesting that an immune deviation induced by Th1-polarizing agents may revert an ongoing Th2 inflammation...
Rhinasthma: a new specific QoL questionnaire for patients with rhinitis and asthmaI Baiardini
Allergy and Respiratory Diseases, DIMI, Genoa University, Genoa, Italy
Allergy 58:289-94. 2003..It provides a short and simple assessment, and has overall psychometric properties. This is of relevance because of the frequent asthma-rhinitis comorbidity...
Standard skin prick testing and sensitization to inhalant allergens across Europe--a survey from the GALEN networkL Heinzerling
Department of Dermatology and Allergy, , Berlin, Germany
Allergy 60:1287-300. 2005..This overview may serve as reference for the practising doctor and suggests a GA(2)LEN Pan-European core SPT panel...
[Advances and gaps in ocular allergies]S Bonini
Arch Soc Esp Oftalmol 80:209-11. 2005
Advances and gaps in ocular allergiesS Bonini
Arch Soc Esp Oftalmol 80:205-7. 2005
Neutrophil and eosinophil participation in atopic and vernal keratoconjunctivitisS D Trocme
Department of Ophthalmology and Visual Sciences, University of Texas Medical Branch, 700 University Boulevard, Galveston, TX 77555 1106, USA
Curr Eye Res 26:319-25. 2003..A retrospective study was conducted at three centers to examine the participation of neutrophils and eosinophils in the inflammatory processes associated with atopic keratoconjunctivitis (AKC) and vernal keratoconjunctivitis (VKC)...
Exercise-induced asthma, respiratory and allergic disorders in elite athletes: epidemiology, mechanisms and diagnosis: part I of the report from the Joint Task Force of the European Respiratory Society (ERS) and the European Academy of Allergy and ClinicaK H Carlsen
Voksentoppen, Department of Paediatrics, Faculty of Medicine, University of Oslo, Rikshospitalet, Norwegian School of Sport Sciences, Oslo, Norway
Allergy 63:387-403. 2008....
