A Bianchetti

..An individualized, multimodal treatment plan addressing the treatment of cognitive, behavioural and functional decline is essential. Aim of the paper is to describe the principal components of the treatment plan of AD patients...

..These data do not permit a conclusion as to the possible mechanism of action of the association of the two treatments...

..The trilinear model of the association between insight and cognitive status reflects more closely the observable decline of insight and can provide estimates of when the decline of insight begins and ends...

..to assess the validity of the Direct Assessment of Functional Status (DAFS) performance-based functional scale for the staging of dementia severity by comparing it with established clinical, functional and cognitive scales...

..To investigate the predictors of caregiver's depressive symptoms in a sample of community-dwelling Alzheimer's patients...

..With regard to the content, no significant differences were observed between AD and MID patients; 53% of psychotic symptoms were found to be paranoid delusions while 47% were misidentification delusions...

..We calculated a regression equation for use in predicting MMSE scores from Itel-MMSE scores. Data fit a linear regression model...

..The data show an overall reduction in behavioral disturbances and a decreased use of psychotropic drugs and physical restraints...

..12 in the oldest age group. It is concluded that the relation of the epsilon4 allele with Alzheimer's disease is age dependent, indicating that other risk factors might be relevant in the younger and older ages...

..Assessment of personality changes in patients with dementia has received little systematic investigation, although caregivers report personality modifications in every phase of dementia...

..To describe atrophic changes of the hippocampus and entorhinal cortex in frontotemporal dementia (FTD) and compare them with those of AD...

..To evaluate the impact of continued Reality Orientation Therapy (ROT) in delaying the outcomes of dementia progression...

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..Disease progression is highly variable, and median survival after the onset of dementia ranges from 5 to 9.3 years. Early recognition of AD allows time to plan for the future, and to treat patients before marked deterioration occurs...

..Patients with dementia are vulnerable to delirium at lower levels of medical acuity than non-demented patients...

..In this paper we present the results of this approach in a large population of AD subjects followed for 36 weeks by 14 AEUs in Eastern Lombardy, Italy...

..Other issues covered are opportunities for Alzheimer's disease prevention, various modalities of care, and the treatment of comorbidities...

..To identify clinical outcomes and variables associated with 6-month mortality in very elderly patients admitted for nonacidotic acute exacerbation of chronic obstructive pulmonary disease (AECOPD)...

..Despite some potential limitations, our results strongly suggest that the Itel-MMSE may be used as a screening test to identify healthy elderly subjects whose cognitive performance is poor...

..MCI and AD patients had significant improvements in global cognitive status and/or in specific cognitive areas. On the contrary, MSA patients did not benefit at all...

..With specificity set to 95%, sensitivity ranged from 57% to 74% for CT-based measures and from 52% to 74% for MR-based measures. CONCLUSION: The rWTH is an accurate marker of AD that could be used in routine clinical settings...