Avi A Weinbroum

Summary

Country: Israel

Publications

  1. ncbi Dextromethorphan reduces immediate and late postoperative analgesic requirements and improves patients' subjective scorings after epidural lidocaine and general anesthesia
    Avi A Weinbroum
    Post-Anesthesia Care Unit, Tel Aviv Sourasky Medical Center, Tel Aviv University, Tel Aviv, Israel
    Anesth Analg 94:1547-52. 2002
  2. ncbi Superiority of postoperative epidural over intravenous patient-controlled analgesia in orthopedic oncologic patients
    Avi A Weinbroum
    Post Anesthesia Care Unit, Tel Aviv Sourasky Medical Center and the Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel
    Surgery 138:869-76. 2005
  3. ncbi Methylene blue attenuates pancreas ischemia-reperfusion (IR)-induced lung injury: a dose response study in a rat model
    Avi A Weinbroum
    Animal Research Laboratory, Tel Aviv Sourasky Medical Center and the Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel
    J Gastrointest Surg 13:1683-91. 2009
  4. ncbi A single small dose of postoperative ketamine provides rapid and sustained improvement in morphine analgesia in the presence of morphine-resistant pain
    Avi A Weinbroum
    Post Anesthesia Care Unit, Tel Aviv Sourasky Medical Center, and the Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel
    Anesth Analg 96:789-95, table of contents. 2003
  5. ncbi Efficiency of the operating room suite
    Avi A Weinbroum
    Post Anesthesia Care Unit, Tel Aviv Sourasky Medical Center, 6 Weizman St, Israel
    Am J Surg 185:244-50. 2003
  6. ncbi Importance of early identification of methylenedioxymethamphetamine ('ecstasy') ingestion in victims of motor vehicle accidents
    Avi A Weinbroum
    Post Anesthesia Care Unit, Tel Aviv Sourasky Medical Center and the Sackler Faculty of Medicine, Tel Aviv University, Israel
    Eur J Emerg Med 10:19-22. 2003
  7. ncbi Mannitol dose-dependently attenuates lung reperfusion injury following liver ischemia reperfusion: a dose-response study in an isolated perfused double-organ model
    A A Weinbroum
    The Post Anesthesia Care Unit and Animal Research Laboratory, Tel Aviv Sourasky Medical Center and the Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel
    Lung 180:327-38. 2002
  8. ncbi Preoperative and postoperative dextromethorphan provides sustained reduction in postoperative pain and patient-controlled epidural analgesia requirement: a randomized, placebo-controlled, double-blind study in lower-body bone malignancy-operated patients
    Avi A Weinbroum
    Post Anesthesia Care Unit, Tel Aviv Sourasky Medical Center, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel
    Cancer 97:2334-40. 2003
  9. ncbi Flumazenil is innocuous in a paroxysmal supraventricular tachycardia and radiofrequency ablation: a paediatric case report and review of the literature
    Avi A Weinbroum
    Post Anaesthesia Care Unit, Tel Aviv Sourasky Medical, Tel Aviv University, Tel Aviv, Israel
    Paediatr Anaesth 13:349-54. 2003
  10. ncbi Mannitol prevents acute lung injury after pancreas ischemia-reperfusion: a dose-response, ex vivo study
    Avi A Weinbroum
    The Animal Research Laboratory, Tel Aviv Sourasky Medical Center and the Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel
    Lung 187:215-24. 2009

Collaborators

Detail Information

Publications77

  1. ncbi Dextromethorphan reduces immediate and late postoperative analgesic requirements and improves patients' subjective scorings after epidural lidocaine and general anesthesia
    Avi A Weinbroum
    Post-Anesthesia Care Unit, Tel Aviv Sourasky Medical Center, Tel Aviv University, Tel Aviv, Israel
    Anesth Analg 94:1547-52. 2002
    ..Subjectively scored levels of pain, sedation, and well-being were better as well...
  2. ncbi Superiority of postoperative epidural over intravenous patient-controlled analgesia in orthopedic oncologic patients
    Avi A Weinbroum
    Post Anesthesia Care Unit, Tel Aviv Sourasky Medical Center and the Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel
    Surgery 138:869-76. 2005
    ..Surgery for bone malignancy is associated with intense postoperative pain. Patient-controlled epidural analgesia (PCEA) and intravenous patient-controlled analgesia (IV-PCA) are used currently for postoperative pain control...
  3. ncbi Methylene blue attenuates pancreas ischemia-reperfusion (IR)-induced lung injury: a dose response study in a rat model
    Avi A Weinbroum
    Animal Research Laboratory, Tel Aviv Sourasky Medical Center and the Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel
    J Gastrointest Surg 13:1683-91. 2009
    ..We now investigated whether methylene blue (MB), a clinically used coloring agent and antioxidant in itself, protected the lung exposed to pancreas IR...
  4. ncbi A single small dose of postoperative ketamine provides rapid and sustained improvement in morphine analgesia in the presence of morphine-resistant pain
    Avi A Weinbroum
    Post Anesthesia Care Unit, Tel Aviv Sourasky Medical Center, and the Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel
    Anesth Analg 96:789-95, table of contents. 2003
    ..Ketamine reduced morphine consumption and provided rapid and sustained improvement in morphine analgesia and in subjective feelings of well-being, without unacceptable side effects...
  5. ncbi Efficiency of the operating room suite
    Avi A Weinbroum
    Post Anesthesia Care Unit, Tel Aviv Sourasky Medical Center, 6 Weizman St, Israel
    Am J Surg 185:244-50. 2003
    ..The need to control high costs of running operating rooms while providing for timely patient care led us to assess the time wasted in the operating room (OR)...
  6. ncbi Importance of early identification of methylenedioxymethamphetamine ('ecstasy') ingestion in victims of motor vehicle accidents
    Avi A Weinbroum
    Post Anesthesia Care Unit, Tel Aviv Sourasky Medical Center and the Sackler Faculty of Medicine, Tel Aviv University, Israel
    Eur J Emerg Med 10:19-22. 2003
    ....
  7. ncbi Mannitol dose-dependently attenuates lung reperfusion injury following liver ischemia reperfusion: a dose-response study in an isolated perfused double-organ model
    A A Weinbroum
    The Post Anesthesia Care Unit and Animal Research Laboratory, Tel Aviv Sourasky Medical Center and the Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel
    Lung 180:327-38. 2002
    ..It is concluded that mannitol in a narrow therapeutic dose range can reduce oxidalive stress-induced lung damage that is related to liver IR...
  8. ncbi Preoperative and postoperative dextromethorphan provides sustained reduction in postoperative pain and patient-controlled epidural analgesia requirement: a randomized, placebo-controlled, double-blind study in lower-body bone malignancy-operated patients
    Avi A Weinbroum
    Post Anesthesia Care Unit, Tel Aviv Sourasky Medical Center, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel
    Cancer 97:2334-40. 2003
    ....
  9. ncbi Flumazenil is innocuous in a paroxysmal supraventricular tachycardia and radiofrequency ablation: a paediatric case report and review of the literature
    Avi A Weinbroum
    Post Anaesthesia Care Unit, Tel Aviv Sourasky Medical, Tel Aviv University, Tel Aviv, Israel
    Paediatr Anaesth 13:349-54. 2003
    ....
  10. ncbi Mannitol prevents acute lung injury after pancreas ischemia-reperfusion: a dose-response, ex vivo study
    Avi A Weinbroum
    The Animal Research Laboratory, Tel Aviv Sourasky Medical Center and the Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel
    Lung 187:215-24. 2009
    ..55 < 0.22 < 1.1 mM) dosages. Amylase and lipase did not contribute to lung injury. Ex vivo acute pancreatitis induces acute lung injury via oxidants/antioxidants imbalance, which is preventable by mannitol...
  11. ncbi Reliability of cardiac output calculation by the fick principle and central venous oxygen saturation in emergency conditions
    Avi A Weinbroum
    Department of Anesthesiology and Critical Care, Tel Aviv Sourasky Medical Center and Sackler Faculty of Medicine, Tel Aviv University, Israel
    J Clin Monit Comput 22:361-6. 2008
    ....
  12. ncbi Morphine with adjuvant ketamine vs higher dose of morphine alone for immediate postthoracotomy analgesia
    Nachum Nesher
    Director, Post Anesthesia Care Unit, Tel Aviv Sourasky Medical Center, 6 Weizman St, Tel Aviv 64239, Israel
    Chest 136:245-52. 2009
    ..We hypothesized that the concomitant use of a subanesthetic dose of ketamine plus a two-third-standard morphine dose might provide more effective analgesia with fewer side effects than a standard morphine dose for early pain control...
  13. ncbi Dextromethorphan-associated epidural patient-controlled analgesia provides better pain- and analgesics-sparing effects than dextromethorphan-associated intravenous patient-controlled analgesia after bone-malignancy resection: a randomized, placebo-control
    Avi A Weinbroum
    Postanesthesia Care Unit, the Acute Pain Service, Tel Aviv Sourasky Medical Center and the Sackler Faculty Medicine, Tel Aviv University, Tel Aviv, Israel
    Anesth Analg 98:714-22, table of contents. 2004
    ..DM patients ambulated earlier than placebo recipients...
  14. ncbi Concomitant administration of mannitol and N-acetylcysteine for the prevention of lung reperfusion injury
    Avi A Weinbroum
    Post Anesthesia Care Unit and Animal Research Laboratory, Tel Aviv Sourasky Medical Center, affiliated to the Sackler Faculty of Medicine, Tel Aviv University, Israel
    J Trauma 60:1290-6. 2006
    ..Mannitol (MN) and N- acetylcysteine (NAC) are partially successful in preventing lung reperfusion injury after liver ischemia reperfusion (IR). Their concomitant administration might enhance the individual effects of each...
  15. ncbi Methylene blue attenuates lung injury after mesenteric artery clamping/unclamping
    A A Weinbroum
    Post Anaesthesia Care Unit, Animal Research Laboratory, Tel Aviv Sourasky Medical Center and the Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel
    Eur J Clin Invest 34:436-42. 2004
    ..This controlled, experimental study was designed to assess the effects of intratracheal and intravenous methylene blue on reperfusion lung injury following superior mesenteric artery clamping/unclamping...
  16. ncbi Multidisciplinary management of life-threatening tracheal obstruction
    Avi A Weinbroum
    Post Anesthesia Care Unit, Tel Aviv Sourasky Medical Center, affiliated with the Sackler Faculty of Medicine, Tel Aviv University, 6 Weizman Street, Tel Aviv 64239, Tel Aviv, Israel
    Resuscitation 64:115-7. 2005
    ..We describe our management to provide safe airway control in a severely dyspnoeic patient with unilateral vocal cord paralysis and a 1mm opening of the lower trachea...
  17. ncbi Pathophysiological and clinical aspects of combat anticholinesterase poisoning
    Avi A Weinbroum
    Post Anaesthesia Care Unit, Tel Aviv Sourasky Medical Centre and Sackler Faculty of Medicine, Tel Aviv University, 6 Weizman Street, Tel Aviv 64239 Israel
    Br Med Bull 72:119-33. 2004
    ..This review summarizes the biochemistry and pathophysiology of anticholinesterase poisoning, the relevant clinical manifestations and the currently available therapeutic strategies...
  18. ncbi N-acetyl-L-cysteine mitigates aortic tone injury following liver ischemia-reperfusion
    Avi A Weinbroum
    Animal Research Laboratory and Post Anesthesia Care Unit, Tel Aviv Sourasky Medical Center and the Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel
    J Cardiovasc Pharmacol 45:509-15. 2005
    ..NAC concentrations directly and inversely correlated with xanthine oxidase activity but not with GSH level. It preserved aortic functions dose-specifically, mainly by oxidant quenching...
  19. ncbi Halothane, isoflurane, and fentanyl increase the minimally effective defibrillation threshold of an implantable cardioverter defibrillator: first report in humans
    Avi A Weinbroum
    Post Anesthesia Care Unit, Department of Anesthesiology and Critical Care, Tel Aviv Sourasky Medical Center, 6 Weizman Street, Tel Aviv 64239, Israel
    Anesth Analg 95:1147-53, table of contents. 2002
    ..Subcutaneous lidocaine plus intermittent small-dose IV propofol minimizes DFT compared with these general anesthetics while providing equal patient satisfaction...
  20. ncbi Wrist actigraphy in anesthesia
    A A Weinbroum
    Post Anesthesia Care Unit, Department of Anesthesiology and Critical Care Medicine, Tel Aviv Sourasky Medical Center, 6 Weizman Street, Tel Aviv 64239, Israel
    J Clin Anesth 13:455-60. 2001
    ..To examine the use of wrist actigraphy during and following anesthesia or monitored sedation and its ability to objectively assess sleep-related events...
  21. ncbi Dextromethorphan attenuation of postoperative pain and primary and secondary thermal hyperalgesia
    A A Weinbroum
    Post Anesthesia Care Unit, Tel Aviv Sourasky Medical Center, and the Sackler Faculty of Medicine Tel Aviv University, Israel
    Can J Anaesth 48:167-74. 2001
    ..To determine the effect of 90 mg dextromethorphan (DM) p.o. vs placebo 90 min preoperatively, on the immediate and delayed postoperative course...
  22. ncbi Lung preconditioning with N-acetyl-L-cysteine prevents reperfusion injury after liver no flow-reflow: a dose-response study
    A A Weinbroum
    Department of Anesthesiology, Tel Aviv Sourasky Medical Center, Israel
    Transplantation 71:300-6. 2001
    ..We now investigated whether preconditioning of lungs with NAC could attenuate lung respiratory or vascular derangement after no flow-reflow (ischemia-reperfusion, IR) and if this depends on lung GSH levels...
  23. ncbi Liver glutathione level influences myocardial reperfusion injury following liver ischemia-reperfusion
    A A Weinbroum
    Department of Anesthesiology, Critical Care Medicine, Tel Aviv Sourasky Medical Center, Israel
    Med Sci Monit 7:1137-44. 2001
    ..N-acetyl-L-cysteine (NAC) both replenishes reduced glutathione (GSH) and mitigates reperfusion injury. We hypothesized that liver content of GSH could affect remote myocardial reperfusion injury following liver ischemia-reperfusion...
  24. ncbi External pacing does not potentiate allopurinol protection of the heart from liver ischemia-reperfusion -- a study in an isolated perfused liver-heart rat model
    A A Weinbroum
    The Post Anesthesia Care Unit, Tel Aviv Sourasky Medical Center, Israel
    Med Sci Monit 7:1145-52. 2001
    ..The objective was to study the effects of low dose allopurinol together with external pacing in attenuating myocardial reperfusion dysfunction following liver IR in the same double organ model...
  25. ncbi Flumazenil improves cognitive and neuromotor emergence and attenuates shivering after halothane-, enflurane- and isoflurane-based anesthesia
    A A Weinbroum
    Post Anesthesia Care Unit, The Department Of Anesthesiology Critical Care Tel Aviv Sourasky Medical Center, The Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel
    Can J Anaesth 48:963-72. 2001
    ..To conduct a randomized, placebo-controlled, double-blinded, clinical experiment testing the hypothesis that flumazenil, a benzodiazepine antagonist, may affect recovery from halothane-, enflurane- and isoflurane-based anesthesia...
  26. ncbi Dextromethorphan and dexmedetomidine: new agents for the control of perioperative pain
    A A Weinbroum
    Post Anaesthesia Care Unit, Tel Aviv Sourasky Medical Centre affiliated to the Sackler Faculty of Medicine, Tel Aviv University, Israel
    Eur J Surg 167:563-9. 2001
    ..It also minimises opioid-induced muscle rigidity, lessens postoperative shivering, causes minimal respiratory depression, and has haemodynamic stabilising effects...
  27. ncbi The midazolam-induced paradox phenomenon is reversible by flumazenil. Epidemiology, patient characteristics and review of the literature
    A A Weinbroum
    Post Anesthesia Care Unit, Tel Aviv Sourasky Medical Center, 6 Weizman St, Tel Aviv 64239, Israel
    Eur J Anaesthesiol 18:789-97. 2001
    ....
  28. ncbi Anaesthesia and critical care considerations in nerve agent warfare trauma casualties
    A A Weinbroum
    Post Anaesthesia Care Unit, Tel Aviv Sourasky Medical Centre, The Sackler Faculty of Medicine, Tel Aviv University, 6 Weizman Street, 64239, Tel Aviv, Israel
    Resuscitation 47:113-23. 2000
    ....
  29. ncbi N-acetyl-L-cysteine for preventing lung reperfusion injury after liver ischemia-reperfusion: a possible dual protective mechanism in a dose-response study
    A A Weinbroum
    Department of Anesthesiology, Tel Aviv Sourasky Medical Center, and the Sackler Faculty of Medicine, Tel Aviv University, Israel
    Transplantation 69:853-9. 2000
    ..We now assessed the therapeutic effect of NAC-in preventing ALI caused by liver IR-if administered to the lung during liver reperfusion...
  30. ncbi Dextromethorphan for the reduction of immediate and late postoperative pain and morphine consumption in orthopedic oncology patients: a randomized, placebo-controlled, double-blind study
    Avi A Weinbroum
    Postanesthesia Care Unit, Tel Aviv Sourasky Medical Center and the Sackler Faculty of Medicine, Tel Aviv University, Israel
    Cancer 95:1164-70. 2002
    ..The authors investigated 75 patients who underwent surgery for bone and soft tissue malignancies, in whom postoperative pain is more severe compared with patients who undergo general surgery...
  31. ncbi The role of dextromethorphan in pain control
    A A Weinbroum
    Department of Anesthesiology and Critical Care, Tel Aviv Sourasky Medical Center, Israel
    Can J Anaesth 47:585-96. 2000
    ..To review the clinical benefits of dextromethorphan (DM) in pain management, describe its neuropharmacological properties...
  32. ncbi Impairment of aortal tone by no flow-reflow conditions and its partial amelioration by mannitol
    A A Weinbroum
    Department of Anesthesiology, Tel Aviv Sourasky Medical Center and the Sackler Faculty of Medicine, Tel Aviv University, Israel
    Ann Thorac Surg 69:1439-44. 2000
    ..Thus, we tested these remote effects in an ex-vivo double organ model...
  33. ncbi Effects of intravenous patient-controlled analgesia with buprenorphine and morphine alone and in combination during the first 12 postoperative hours: a randomized, double-blind, four-arm trial in adults undergoing abdominal surgery
    Stanislav Oifa
    Department of Anesthesia, Tel Aviv Sourasky Medical Center and the Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel
    Clin Ther 31:527-41. 2009
    ..Buprenorphine (BUP) is not typically used intravenously in this setting, particularly in combination with morphine (MO), due to concerns that BUP might inhibit the analgesic effect of MO...
  34. ncbi Subanaesthetic ketamine spares postoperative morphine and controls pain better than standard morphine does alone in orthopaedic-oncological patients
    Yehuda Kollender
    Department of Orthopaedic Oncology, Tel Aviv Sourasky Medical Centre and the Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel
    Eur J Cancer 44:954-62. 2008
    ....
  35. ncbi Low-dose ketamine via intravenous patient-controlled analgesia device after various transthoracic procedures improves analgesia and patient and family satisfaction
    Shoshana Chazan
    Tel Aviv Sourasky Medical Center, Tel Aviv University, Tel Aviv, Israel
    Pain Manag Nurs 11:169-76. 2010
    ....
  36. ncbi Ketamine spares morphine consumption after transthoracic lung and heart surgery without adverse hemodynamic effects
    Nahum Nesher
    Department of Cardiothoracic Surgery, Tel Aviv Medical Center and the Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel
    Pharmacol Res 58:38-44. 2008
    ..We hypothesized that by combining a sub-anesthetic dose of ketamine with morphine, we could effectively control pain with less morphine and minimize drowsiness, while maintaining safe hemodynamic and respiratory parameters...
  37. ncbi Ketamine for acute and subacute pain in opioid-tolerant patients
    Shoshana Chazan
    Acute Pain Service, Tel Aviv Sourasky Medical Center, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel
    J Opioid Manag 4:173-80. 2008
    ..It is effective even when mega doses of IV, epidural, or oral opioids prove ineffective and when signs of tolerance have developed...
  38. ncbi Mannitol attenuates kidney damage induced by xanthine oxidase-associated pancreas ischemia-reperfusion
    Wisam Khoury
    Division of Surgery B, Tel Aviv Sourasky Medical Center and the Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel
    J Surg Res 160:163-8. 2010
    ..It may be propagated by xanthine oxidase (XO)-generated oxidant stress. We investigated whether pancreas IR directly and acutely induces renal dysfunction and if this outcome could be prevented by mannitol...
  39. ncbi Electromechanical impairment of human auricle and rat myocardial strip subjected to exogenous oxidative stress
    Ron Ben Abraham
    Departments of Anesthesiology and Critical Care, Tel Aviv Sourasky Medical Center and the Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel
    Eur J Cardiothorac Surg 23:66-73. 2003
    ..CONCLUSIONS: Remotely and exogenously originated oxidative burst directly induces electromechanical dysfunction and disrupts oxidant/antioxidant balance in human auricles as it does in the rat myocardial strip...
  40. ncbi Ventilatory and hemodynamic changes during retroperitoneal and transperitoneal laparoscopic nephrectomy: a prospective real-time comparison
    Andrei Nadu
    Department of Urology, Tel Aviv Sourasky Medical Center and Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel
    J Urol 174:1013-7. 2005
    ..05). CONCLUSIONS: Nephrectomy via the retroperitoneal laparoscopic approach interferes with ventilatory and hemodynamic functions less than nephrectomy via the transperitoneal approach...
  41. ncbi Dextromethorphan mitigates phantom pain in cancer amputees
    Ron Ben Abraham
    Post-Anesthesia Care Unit and Acute Pain Service, Tel Aviv Sourasky Medical Center and Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel
    Ann Surg Oncol 10:268-74. 2003
    ..Three patients stopped all previous analgesic use during the study. CONCLUSIONS: Persistent phantom pain probably involves NMDA receptor hyperexcitability because DM 120 to 270 mg/day mitigated the pain satisfactorily...
  42. ncbi Mesenteric artery clamping/unclamping-induced acute lung injury is attenuated by N-methyl-D-aspartate antagonist dextromethorphan
    R Ben-Abraham
    Animal Research Laboratory, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel
    Lung 184:309-17. 2006
    ..Thus, Intravenous dextromethorphan mitigates lung reperfusion injury following SMA clamping/unclamping in a dose-dependent manner. This is a novel potential use of dextromethorphan in vivo...
  43. ncbi CobraPLA Insertion by anesthetists and non-anesthetists wearing unconventional protective gear: a prospective study in humans
    Ron Ben-Abraham
    Anesthesia and Critical Care Department, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel
    Med Sci Monit 14:PI13-8. 2008
    ..We assessed the performance of anesthesia and non-anesthesia residents in inserting the CobraPLA, a supraglottic airway device, on consecutive anesthetized patients, to assess its potential use under simulated conditions...
  44. ncbi Laryngeal mask airway insertion by anesthetists and nonanesthetists wearing unconventional protective gear: a prospective, randomized, crossover study in humans
    Ron Flaishon
    Anesthesiology and Critical Care Department and Outpatient Surgery and Post-Anesthesia Care Units, Tel Aviv Sourasky Medical Center and the Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel
    Anesthesiology 100:267-73. 2004
    ..Novices initially perform at the level of surgical residents, but their learning curve was quick under both conditions...
  45. ncbi Repeated and escalating preoperative subanesthetic doses of ketamine for postoperative pain control in patients undergoing tumor resection: a randomized, placebo-controlled, double-blind trial
    Evgeny Rakhman
    Department of Anesthesia and CCM, Tel Aviv Sourasky Medical Center, Tel Aviv University, Tel Aviv, Israel
    Clin Ther 33:863-73. 2011
    ..Ketamine induces a short-term effect on postoperative pain when administered intravenously immediately before or during acute pain. Repeated administration of low-dose ketamine may induce long-term pain relief in chronic pain syndromes...
  46. ncbi Effects of methylene blue and volatile anesthetics on survival in a murine hemorrhage resuscitation model
    Boris Aptekman
    Department of Anesthesia and Intensive Care Medicine, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel
    J Trauma 69:1433-40; discussion 1440-1. 2010
    ....
  47. ncbi Renal apoptosis following carbon dioxide pneumoperitoneum in a rat model
    Wisam Khoury
    Department of Surgery B and Transplantation Unit, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel
    J Urol 180:1554-8. 2008
    ..We investigated the effects of CO(2) induced pneumoperitoneum on kidney function, as reflected by blood and urine creatinine levels, and its relation with renal cell apoptosis...
  48. ncbi The hemodynamic effects of CO2-induced pressure on the kidney in an isolated perfused rat kidney model
    Wisam Khoury
    Division of General Surgery B, Tel Aviv Sourasky Medical Center, The Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel
    Surg Laparosc Endosc Percutan Tech 18:573-8. 2008
    ..Variable mechanisms were suggested to mediate the changes in renal hemodynamics during pneumoperitoneum. To assess whether it can be pressure dependent only, we conduct a study in an isolated, pressurized, and perfused organ model...
  49. ncbi Antichemical protective gear prolongs time to successful airway management: a randomized, crossover study in humans
    Ron Flaishon
    Department of Anesthesiology and Critical Care Medicine, Directorate, and Outpatient Surgery and Post-Anesthesia Care Units, Tel Aviv Sourasky Medical Center and the Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel
    Anesthesiology 100:260-6. 2004
    ..If chances for rapid and successful tracheal intubation under such chaotic conditions are poor, laryngeal mask airway insertion is a viable choice for airway management until a proper secured airway is obtainable...
  50. ncbi Dextromethorphan for phantom pain attenuation in cancer amputees: a double-blind crossover trial involving three patients
    Ron Ben Abraham
    Post Anesthesia Care Unit, Tel Aviv Sourasky Medical Center and the Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel
    Clin J Pain 18:282-5. 2002
    ..CONCLUSIONS: Further clinical trials are warranted to determine the optimal dosage and identify which patients with phantom pain would benefit the most from this therapeutic approach...
  51. ncbi Laparoscopic surgery may be associated with severe pain and high analgesia requirements in the immediate postoperative period
    Perla Ekstein
    Department of Anesthesia and Intensive Care Medicine, Tel Aviv Sourasky Medical Center and the Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel
    Ann Surg 243:41-6. 2006
    ..By 24 hours, the former are in less pain than the latter...
  52. ncbi Supraglottic devices: a possible role in prehospital toxic mass casualty event?
    Ron Ben-Abraham
    Department of Anesthesiology and Critical Care Medicine, Tel Aviv Sourasky Medical Center, Israel
    J Med 35:105-14. 2004
    ....
  53. ncbi Prophylactic fluconazole does not improve outcome in patients with purulent and fecal peritonitis due to lower gastrointestinal perforation
    Wisam Khoury
    Division of General Surgery B, Tel Aviv Sourasky Medical Center, 6 Weizman Street, Tel Aviv 64239, Israel
    Am Surg 76:197-202. 2010
    ..5%, and 58% vs 35%, respectively). Empiric fluconazole in patients with peritonitis associated with LGIT perforation did not improve patients' outcome compared with those without empiric treatment...
  54. ncbi Inhaled nitric oxide improves pulmonary functions following massive pulmonary embolism: a report of four patients and review of the literature
    Oded Szold
    Surgical Intensive Care Unit, Tel Aviv Sourasky Medical Center and Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel
    Lung 184:1-5. 2006
    ..Inhaled NO may be useful in treating acute massive pulmonary embolism. This potential application warrants further investigation...
  55. ncbi Dextromethorphan premedication reduces midazolam requirement: objective and subjective parameters in peribronchoscopy
    Yehuda Schwarz
    Department of Pulmonology, Tel Aviv Medical Center, Sackler Faculty of Medicine, Tel Aviv, Israel
    Respiration 74:314-9. 2007
    ..Also prior to the procedure patients show high levels of anxiety due to fear of the pain and breathing difficulties that they might experience during the procedure...
  56. ncbi Application of a cuirass and institution of biphasic extra-thoracic ventilation by gear-protected physicians
    Ron Ben-Abraham
    Department of Anesthesiology, Tel Aviv Sourasky Medical Center, Tel Aviv University, Israel
    J Crit Care 19:36-41. 2004
    ..Extra-thoracic ventilation should be further evaluated as an option for emergent respiratory support during toxic mass casualty events...
  57. ncbi 'Ecstasy' intoxication: life-threatening manifestations and resuscitative measures in the intensive care setting
    Ron Ben-Abraham
    Department of Anesthesiology and Critical Care, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel
    Eur J Emerg Med 10:309-13. 2003
    ....
  58. ncbi Attenuation of liver ischemia-reperfusion-induced atrial dysfunction by external pacing but not by isoproterenol
    Ron Ben-Abraham
    Department of Anesthesiology and Critical Care, Tel Aviv Sourasky Medical School, 6 Weizman Street, Tel Aviv 64239, Israel
    Can J Physiol Pharmacol 82:9-15. 2004
    ..05 vs. baseline control ischemia-paced strips). Thus, external electrical pacing prevented liver ischemia-reperfusion-induced atrial strips' bradycardia and loss of contractility, while isoproterenol did not...
  59. ncbi Methylene blue in preventing hemodynamic and metabolic derangement following superior mesenteric artery clamping/unclamping: an intratracheal vs. intraperitoneal dose-response study
    Avi A Weinbroum
    Post-Anesthesia Care Unit, Tel-Aviv Sourasky Medical Center, Sackler Faculty of Medicine, Tel-Aviv University, Israel
    Shock 17:372-6. 2002
    ..No drug regimen affected heart rate. We concluded that intraperitoneal and intratracheal MB at specific doses prevented systemic derangement following SMA clamping/unclamping...
  60. ncbi Effect of small bowel perforation during laparoscopy on end-tidal carbon dioxide: observation in a small animal model
    Shmuel Avital
    Department of Surgery A, Tel Aviv Sourasky Medical Center and the Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel
    J Surg Res 143:368-71. 2007
    ..The aim of this study was to assess the influence of small bowel perforation during laparoscopy on ETCO(2) in a rat model...
  61. ncbi Secondary reconstruction of the extensor mechanism using part of the quadriceps tendon, patellar retinaculum, and Gore-Tex strips after proximal tibial resection
    Yehuda Kollender
    National Unit of Orthopedic Oncology, Tel Aviv Sourasky Medical Center, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel
    J Arthroplasty 19:354-60. 2004
    ..All patients had good to excellent functional outcomes and reported no limitations in daily life activities...
  62. ncbi Immediate postoperative pain in orthopedic patients is more intense and requires more analgesia than in post-laparotomy patients
    Margaret P Ekstein
    Department of Anesthesia and Intensive Care Medicine, Tel Aviv Sourasky Medical Center and the Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel
    Pain Med 12:308-13. 2011
    ..To compare the immediate postoperative pain intensity between orthopedic and general surgery patients and evaluate the extent of severe pain in each group...
  63. ncbi Flumazenil attenuates development of tolerance to diazepam after chronic treatment of mice with either isoflurane or diazepam
    Ron Flaishon
    Department of Anesthesiology and Critical Care Medicine, Tel Aviv Sourasky Medical Center, and the Sackler Faculty of Medicine, Tel Aviv, Israel
    Anesth Analg 97:1046-52, table of contents. 2003
    ..These findings suggest that isoflurane and diazepam share a mechanism of action, most probably via the gamma-aminobutyric acid system and the CBR...
  64. ncbi Monitored anaesthesia care in the elderly: guidelines and recommendations
    Margaret Ekstein
    Department of Anesthesia and Critical Care Medicine, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel
    Drugs Aging 25:477-500. 2008
    ..In this way, a huge range of procedures can be safely performed in our aging population with expectations for a full and early return to baseline functional status...
  65. ncbi Increased propofol requirement during succeeding administrations for electroconvulsive therapy
    Yitzhak Cohen
    Department of Anesthesiology and Critical Care Medicine, Tel Aviv Sourasky Medical Center and the Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel
    J Clin Anesth 16:282-5. 2004
    ..CONCLUSIONS: Repeated injections of propofol in patients undergoing ECT under deep sedation can induce a tolerance-like reaction to the drug...
  66. ncbi Nontoxic effect of tacrolimus on normally perfused isolated liver and protective effect on hypoperfused liver
    Richard Nakache
    Organ Transplantation Unit, Tel Aviv Sourasky Medical Center and the Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel
    Med Sci Monit 13:BR32-9. 2007
    ....
  67. ncbi The endotracheal tube moves more often in obese patients undergoing laparoscopy compared with open abdominal surgery
    Tiberiu Ezri
    Department of Anesthesiology, Wolfson Medical Center, Holon, Israel
    Anesth Analg 96:278-82, table of contents. 2003
    ..The Rapiscope identifies all these changes, but not the clinically available variables...
  68. ncbi Practical guidelines for acute care of victims of bioterrorism: conventional injuries and concomitant nerve agent intoxication
    Ron Ben Abraham
    Department of Anesthesiology and Critical Care Medicine, Tel Aviv Sourasky Medical Center and the Sackler Faculty of Medicine, Tel Aviv University, Israel
    Anesthesiology 97:989-1004. 2002
  69. ncbi Resuscitative challenges in nerve agent poisoning
    Ron Ben Abraham
    Department of Anesthesiology and Critical Care Medicine, Tel Aviv Sourasky Medical Center and the Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel
    Eur J Emerg Med 10:169-75. 2003
    ..In this review, we summarize the knowledge on the possible pharmacological interactions between nerve agents and acute care...
  70. ncbi Role of adjuvant cryosurgery in intralesional treatment of sacral tumors
    Yehuda Kollender
    National Orthopedic Oncology Unit, Tel-Aviv Sourasky Medical Center, Sackler Faculty of Medicine, Tel Aviv University, Israel
    Cancer 97:2830-8. 2003
    ..CONCLUSIONS: Cryosurgery is a conservative, feasible, and safe adjuvant technique in the treatment of sacral tumors. It is associated with minimal permanent neurologic and vascular injury compared with sacrectomy...
  71. ncbi Laryngeal mask airway control versus endotracheal intubation by medical personnel wearing protective gear
    Ron Ben-Abraham
    Department of Anesthesiology and Critical Care, Tel Aviv University, Israel
    Am J Emerg Med 22:24-6. 2004
    ....
  72. ncbi Postoperative discomfort (other than pain) - a neglected feature of postanesthesia patient care
    Alexander Zegerman
    Post Anesthesia Care Unit, Tel Aviv Sourasky Medical Center, 6 Weizman St, Tel Aviv 64239, Israel
    J Clin Monit Comput 22:279-84. 2008
    ..We assessed the extent of unreported distressing or unpleasant events among patients who had undergone general surgery or orthopedic procedures under standard general anesthesia and their recall 24 h afterwards...
  73. ncbi Carbon dioxide pneumoperitoneum-related liver injury is pressure dependent: A study in an isolated-perfused organ model
    Amir Szold
    Endoscopic Surgery Service, Tel Aviv Sourasky Medical Center and the Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel
    Surg Endosc 22:365-71. 2008
    ..The extent, duration and reversibility of such an injury are unknown. An isolated organ model was used to assess reversibility of liver injury in a CO(2)-pneumoperitoneum-like environment...
  74. ncbi Higher levels of serum cytokines and myocardial tissue markers during on-pump versus off-pump coronary artery bypass surgery
    Nahum Nesher
    Department of Cardiothoracic Surgery, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel
    J Card Surg 21:395-402. 2006
    ..High levels of these factors could correlate with myocardial damage during coronary artery bypass surgery. This finding warrants further laboratory and clinical confirmation in the future...
  75. ncbi An evaluation of general and spinal anesthesia techniques for prostate brachytherapy in a day surgery setting
    Ron Flaishon
    Department of Anesthesiology, Tel Aviv Sourasky Medical Center 6, Weizmann St, Tel Aviv 64239, Israel
    Anesth Analg 101:1656-8. 2005
    ..TIVA allows for earliest voiding and therefore fastest discharge home. Spinal block with 2.5 mg of bupivacaine plus 25 mug of fentanyl provides earlier voiding and consequently earlier discharge than 5 mg of bupivacaine alone...
  76. ncbi Wearing surgical attire outside the operating room: a survey of habits of anesthesiologists and surgeons in Israel
    Avi A Weinbroum
    Post Anesthesia Care Unit, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel
    J Am Coll Surg 205:314-8. 2007
    ..We assessed physicians' attitudes and behavior about OR attire in non-OR areas...
  77. ncbi Interleukin-8 secretion following cardiopulmonary bypass in children as a marker of early postoperative morbidity
    Ron Ben-Abraham
    Department of Anesthesiology and Critical Care Medicine, Tel-Aviv Sourasky Medical Center, Israel
    Paediatr Anaesth 12:156-61. 2002
    ..IL-8 release may be related to some of the haemodynamic changes in the early postoperative course following CPB. The relationship between IL-8 and late markers of patient outcome in high-risk infants awaits further studies...