J Silver

Summary

Affiliation: The Hebrew University
Country: Israel

Publications

  1. ncbi Cellular and molecular mechanisms of secondary hyperparathyroidism
    J Silver
    Department of Nephrology and Hypertension Services, Hadassah University Hospital, Jerusalem, Israel
    Clin Nephrol 63:119-26. 2005
  2. ncbi Regulation of the parathyroid hormone gene by vitamin D, calcium and phosphate
    J Silver
    Minerva Center for Calcium, Hadassah University Hospital, Hebrew University School of Medicine, Jerusalem, Israel
    Kidney Int Suppl 73:S2-7. 1999
  3. ncbi Molecular mechanisms of secondary hyperparathyroidism
    J Silver
    Minerva Center for Calcium and Bone Metabolism, Hadassah Hospital and Hebrew University, Hadassah Medical School, Jerusalem, Israel
    Pediatr Nephrol 14:626-8. 2000
  4. ncbi Calcitonin gene regulation in vivo
    J Silver
    Minerva Center for Calcium and Bone Metabolism, Hadassah University Hospital, Jerusalem, Israel
    Horm Metab Res 25:470-2. 1993
  5. ncbi A conserved cis-acting element in the parathyroid hormone 3'-untranslated region is sufficient for regulation of RNA stability by calcium and phosphate
    R Kilav
    Minerva Center for Calcium and Bone Metabolism, Nephrology Services, Hadassah University Hospital, Jerusalem il-91120, Israel
    J Biol Chem 276:8727-33. 2001
  6. ncbi Dynein light chain binding to a 3'-untranslated sequence mediates parathyroid hormone mRNA association with microtubules
    E Epstein
    Minerva Center for Calcium and Bone Metabolism, Nephrology Services, Hadassah University Hospital, Jerusalem, Israel 91120
    J Clin Invest 105:505-12. 2000
  7. ncbi Parathyroid hormone gene expression in Hyp mice fed a low-phosphate diet
    K H Marks
    Minerva Center for Calcium and Bone Metabolism, Hadassah University Hospital, Jerusalem, Israel
    Nephrol Dial Transplant 12:1581-5. 1997
  8. ncbi The details bedevil DCOR
    J Silver
    Minerva Center for Calcium and Bone Metabolism, Nephrology and Hypertension Services, Hadassah Hebrew University Medical Center, Jerusalem, Israel
    Kidney Int 72:1041-3. 2007
  9. ncbi The IBD1 locus for susceptibility to Crohn's disease has a greater impact in Ashkenazi Jews with early onset disease
    P N Akolkar
    Department of Medicine, North Shore University Hospital/New York University School of Medicine, Manhasset 11030, USA
    Am J Gastroenterol 96:1127-32. 2001
  10. ncbi Role of Thy-1 in T cell development
    D M Page
    Department of Biology and the Cancer Center, University of California at San Diego, La Jolla 92093, USA
    J Immunol 159:5285-92. 1997

Collaborators

  • Tally Naveh-Many
  • S M King
  • Rafael Levi
  • R Kilav
  • P N Akolkar
  • E Epstein
  • D M Page
  • K H Marks
  • R Desnick
  • M Daly
  • X Y Lin
  • D Present
  • B Gulwani-Akolkar
  • J Levine
  • L Mayer
  • Z Zhou
  • S Katz
  • B Gelb
  • J K Yisraeli
  • A Sela-Brown
  • I Ringel
  • S E Benashski
  • C L Stewart
  • Y Tokugawa
  • E Berman

Detail Information

Publications11

  1. ncbi Cellular and molecular mechanisms of secondary hyperparathyroidism
    J Silver
    Department of Nephrology and Hypertension Services, Hadassah University Hospital, Jerusalem, Israel
    Clin Nephrol 63:119-26. 2005
    ..These findings may help guide the development of novel therapies for secondary hyperparathyroidism...
  2. ncbi Regulation of the parathyroid hormone gene by vitamin D, calcium and phosphate
    J Silver
    Minerva Center for Calcium, Hadassah University Hospital, Hebrew University School of Medicine, Jerusalem, Israel
    Kidney Int Suppl 73:S2-7. 1999
    ..The characterization of the parathyroid cytosolic proteins that interact with the PTH mRNA 3'-UTR may lead to a clearer understanding of how changes in serum calcium and phosphate result in secondary hyperparathyroidism...
  3. ncbi Molecular mechanisms of secondary hyperparathyroidism
    J Silver
    Minerva Center for Calcium and Bone Metabolism, Hadassah Hospital and Hebrew University, Hadassah Medical School, Jerusalem, Israel
    Pediatr Nephrol 14:626-8. 2000
    ..The understanding of the molecular mechanisms involved in the genesis of secondary hyperparathyroidism will allow the design of new effective strategies in the management of this troubling condition...
  4. ncbi Calcitonin gene regulation in vivo
    J Silver
    Minerva Center for Calcium and Bone Metabolism, Hadassah University Hospital, Jerusalem, Israel
    Horm Metab Res 25:470-2. 1993
    ..Estrogens given to ovariectomized rats led to increases in calcitonin mRNA. The estrogen receptor was present in the thyroid C-cells. Therefore the calcitonin gene is regulated by vitamin D and estrogens, but not by calcium...
  5. ncbi A conserved cis-acting element in the parathyroid hormone 3'-untranslated region is sufficient for regulation of RNA stability by calcium and phosphate
    R Kilav
    Minerva Center for Calcium and Bone Metabolism, Nephrology Services, Hadassah University Hospital, Jerusalem il-91120, Israel
    J Biol Chem 276:8727-33. 2001
    ..This defined element in the PTH mRNA 3'-UTR is necessary and sufficient for the regulation of PTH mRNA stability by calcium and phosphate...
  6. ncbi Dynein light chain binding to a 3'-untranslated sequence mediates parathyroid hormone mRNA association with microtubules
    E Epstein
    Minerva Center for Calcium and Bone Metabolism, Nephrology Services, Hadassah University Hospital, Jerusalem, Israel 91120
    J Clin Invest 105:505-12. 2000
    ..The dynein complex may be the motor that is responsible for transporting mRNAs to specific locations in the cytoplasm and for the consequent is asymmetric distribution of translated proteins in the cell...
  7. ncbi Parathyroid hormone gene expression in Hyp mice fed a low-phosphate diet
    K H Marks
    Minerva Center for Calcium and Bone Metabolism, Hadassah University Hospital, Jerusalem, Israel
    Nephrol Dial Transplant 12:1581-5. 1997
    ..Phosphate directly regulates the parathyroid (PT) in normal rats and it is of interest whether this regulation is intact in Hyp mice...
  8. ncbi The details bedevil DCOR
    J Silver
    Minerva Center for Calcium and Bone Metabolism, Nephrology and Hypertension Services, Hadassah Hebrew University Medical Center, Jerusalem, Israel
    Kidney Int 72:1041-3. 2007
    ..Dialysis Clinical Outcomes Revisited (DCOR) is an outcomes study on the effect of sevelamer compared with calcium-based phosphorus binders in dialysis patients. It does not show a clear superiority of one compound over the other...
  9. ncbi The IBD1 locus for susceptibility to Crohn's disease has a greater impact in Ashkenazi Jews with early onset disease
    P N Akolkar
    Department of Medicine, North Shore University Hospital/New York University School of Medicine, Manhasset 11030, USA
    Am J Gastroenterol 96:1127-32. 2001
    ..CONCLUSIONS: The IBD1 gene plays a greater role in conferring susceptibility to CD in Jews with early onset disease than in Jews with late onset disease...
  10. ncbi Role of Thy-1 in T cell development
    D M Page
    Department of Biology and the Cancer Center, University of California at San Diego, La Jolla 92093, USA
    J Immunol 159:5285-92. 1997
    ..This finding is discussed in light of recent data regarding the role of other glycosyl-phosphatidylinositol-linked proteins in thymocyte development...
  11. ncbi Development and aging of the eye in mice with inherited optic nerve aplasia: histopathological studies
    J Silver
    Exp Eye Res 38:257-66. 1984
    ..Retinal rosettes were also commonly present...