Research Topics
Species | Sarit CohenSummaryAffiliation: Tel Aviv University Country: Israel Publications
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Publications
Formation of extrachromosomal circles from telomeric DNA in Xenopus laevisSarit Cohen
Institute of Human Genetics, CNRS, Genome Dynamics and Development, 141 rue de la Cardonille, 34396 Montpellier Cedex 5, France
EMBO Rep 3:1168-74. 2002..These results reveal an unusual plasticity of telomeric DNA during normal development of Xenopus...
Extrachromosomal circular DNA of tandemly repeated genomic sequences in DrosophilaSarit Cohen
Department of Molecular Microbiology and Biotechnology, Tel Aviv University, Tel Aviv 69978, Israel
Genome Res 13:1133-45. 2003..Mutations in the genes okra, mus309, and mei41 did not affect eccDNA under normal conditions or following mutagen treatment, implying that eccDNA formation is different from known pathways of DNA repair...
Evidence for rolling circle replication of tandem genes in DrosophilaSarit Cohen
Department of Molecular Microbiology and Biotechnology, Tel Aviv University Tel Aviv 69978, Israel
Nucleic Acids Res 33:4519-26. 2005..RCIs are detected throughout the life cycle of Drosophila and in cultured fly cells. These structures are found regardless of the expression of the replicated gene or of its chromosomal copy number...
Extrachromosomal circular DNA derived from tandemly repeated genomic sequences in plantsSarit Cohen
Department of Molecular Microbiology and Biotechnology, Tel Aviv University, Tel Aviv, Israel
Plant J 53:1027-34. 2008..This mechanism may involve looping-out via intrachromosomal homologous recombination. The implications of these results on genome plasticity and evolutionary processes are discussed...
Extrachromosomal circular DNA in eukaryotes: possible involvement in the plasticity of tandem repeatsS Cohen
Department of Molecular Microbiology and Biotechnology, Tel Aviv University, Tel Aviv, Israel
Cytogenet Genome Res 124:327-38. 2009..This review summarizes recent experimental data which characterizes eccDNA in several organisms using 2D gel electrophoresis, and discusses its possible implications on the dynamics of chromosomal tandem repeats...
Extrachromosomal circles of satellite repeats and 5S ribosomal DNA in human cellsSarit Cohen
Department of Molecular Microbiology and Biotechnology Tel Aviv University, Tel Aviv 69978, Israel
Mob DNA 1:11. 2010..Using this technique we have previously demonstrated that most of eccDNA consists of exact multiples of chromosomal tandemly repeated DNA, including both coding genes and satellite DNA...
