Y Nadir

Summary

Country: Israel

Publications

  1. ncbi Heparanase procoagulant effects and inhibition by heparins
    Yona Nadir
    Thrombosis and Hemostasis Unit, Department of Hematology, Rambam Health Care Campus, Haifa, Israel
    Thromb Res 125:S72-6. 2010
  2. ncbi Heparanase, tissue factor, and cancer
    Yona Nadir
    Thrombosis and Hemostasis Unit, Department of Hematology, Rambam Medical Center, Haifa, Israel
    Semin Thromb Hemost 34:187-94. 2008
  3. ncbi Hemostatic balance on the surface of leukemic cells: the role of tissue factor and urokinase plasminogen activator receptor
    Yona Nadir
    Department of Hematology and Bone Marrow Transplantation, Rambam Medical Center, Haifa, Israel
    Haematologica 90:1549-56. 2005
  4. ncbi Association of homocysteine, vitamin B12, folic acid, and MTHFR C677T in patients with a thrombotic event or recurrent fetal loss
    Y Nadir
    Thrombosis and Hemostasis Unit, Department of Hematology, Rambam Medical Center, Haifa, Israel
    Ann Hematol 86:35-40. 2007
  5. ncbi A fatal case of enoxaparin induced skin necrosis and thrombophilia
    Yona Nadir
    Department of Hematology and Bone Marrow Transplantation, Thrombosis and Hemostasis Unit, Rambam Medical Centre and Bruce Rappaport Faculty of Medicine, Haifa, Israel
    Eur J Haematol 77:166-8. 2006
  6. ncbi Heparanase induces tissue factor expression in vascular endothelial and cancer cells
    Y Nadir
    Cancer and Vascular Biology Research Center, The Bruce Rappaport Faculty of Medicine, Technion, Haifa, Israel
    J Thromb Haemost 4:2443-51. 2006
  7. ncbi Heparanase, heparin and the coagulation system in cancer progression
    Israel Vlodavsky
    Cancer and Vascular and Biology Research Center, The Bruce Rappaport Faculty of Medicine, Technion, Haifa, Israel
    Thromb Res 120:S112-20. 2007
  8. ncbi Heparanase induces tissue factor pathway inhibitor expression and extracellular accumulation in endothelial and tumor cells
    Yona Nadir
    Cancer and Vascular Biology Research Center, The Bruce Rappaport Faculty of Medicine, Technion, Haifa 31096, Israel
    Thromb Haemost 99:133-41. 2008
  9. ncbi An ELISA method for the detection and quantification of human heparanase
    Itay Shafat
    Cancer and Vascular Biology Research Center, The Bruce Rappaport Faculty of Medicine, Technion, Haifa 31096, Israel
    Biochem Biophys Res Commun 341:958-63. 2006
  10. ncbi Leukomogenic factors downregulate heparanase expression in acute myeloid leukemia cells
    Rinat Eshel
    The Hematology Institute, Sourasky Medical Center, Tel Aviv, Israel
    Biochem Biophys Res Commun 335:1115-22. 2005

Collaborators

Detail Information

Publications11

  1. ncbi Heparanase procoagulant effects and inhibition by heparins
    Yona Nadir
    Thrombosis and Hemostasis Unit, Department of Hematology, Rambam Health Care Campus, Haifa, Israel
    Thromb Res 125:S72-6. 2010
    ....
  2. ncbi Heparanase, tissue factor, and cancer
    Yona Nadir
    Thrombosis and Hemostasis Unit, Department of Hematology, Rambam Medical Center, Haifa, Israel
    Semin Thromb Hemost 34:187-94. 2008
    ..As heparins are strong inhibitors of heparanase, in view of the effect of heparanase on TF/TFPI pathway, the role of heparins' anticoagulant activity may potentially be expanded...
  3. ncbi Hemostatic balance on the surface of leukemic cells: the role of tissue factor and urokinase plasminogen activator receptor
    Yona Nadir
    Department of Hematology and Bone Marrow Transplantation, Rambam Medical Center, Haifa, Israel
    Haematologica 90:1549-56. 2005
    ....
  4. ncbi Association of homocysteine, vitamin B12, folic acid, and MTHFR C677T in patients with a thrombotic event or recurrent fetal loss
    Y Nadir
    Thrombosis and Hemostasis Unit, Department of Hematology, Rambam Medical Center, Haifa, Israel
    Ann Hematol 86:35-40. 2007
    ..The results raise doubt as to whether the current routine evaluation of HHC, as part of thrombophilia workup, truly reflects the increased risk of thrombosis...
  5. ncbi A fatal case of enoxaparin induced skin necrosis and thrombophilia
    Yona Nadir
    Department of Hematology and Bone Marrow Transplantation, Thrombosis and Hemostasis Unit, Rambam Medical Centre and Bruce Rappaport Faculty of Medicine, Haifa, Israel
    Eur J Haematol 77:166-8. 2006
    ..The concomitant combined thrombophilia possibly aggravated the patient's clinical presentation...
  6. ncbi Heparanase induces tissue factor expression in vascular endothelial and cancer cells
    Y Nadir
    Cancer and Vascular Biology Research Center, The Bruce Rappaport Faculty of Medicine, Technion, Haifa, Israel
    J Thromb Haemost 4:2443-51. 2006
    ..CONCLUSIONS: Our results indicate that in addition to its well-known function as an enzyme paving a way for invading cells, heparanase also participates in the regulation of TF gene expression and its related coagulation pathways...
  7. ncbi Heparanase, heparin and the coagulation system in cancer progression
    Israel Vlodavsky
    Cancer and Vascular and Biology Research Center, The Bruce Rappaport Faculty of Medicine, Technion, Haifa, Israel
    Thromb Res 120:S112-20. 2007
    ....
  8. ncbi Heparanase induces tissue factor pathway inhibitor expression and extracellular accumulation in endothelial and tumor cells
    Yona Nadir
    Cancer and Vascular Biology Research Center, The Bruce Rappaport Faculty of Medicine, Technion, Haifa 31096, Israel
    Thromb Haemost 99:133-41. 2008
    ....
  9. ncbi An ELISA method for the detection and quantification of human heparanase
    Itay Shafat
    Cancer and Vascular Biology Research Center, The Bruce Rappaport Faculty of Medicine, Technion, Haifa 31096, Israel
    Biochem Biophys Res Commun 341:958-63. 2006
    ..It detects heparanase at concentrations as low as 200 pg/ml and is suitable for quantification of heparanase in tissue extracts and urine...
  10. ncbi Leukomogenic factors downregulate heparanase expression in acute myeloid leukemia cells
    Rinat Eshel
    The Hematology Institute, Sourasky Medical Center, Tel Aviv, Israel
    Biochem Biophys Res Commun 335:1115-22. 2005
    ..In summary, we have characterized a link between leukomogenic factors and the downregulation of heparanase in myeloid leukemic cells...
  11. ncbi Drug-related thrombosis in hematologic malignancies
    Yona Nadir
    Thrombosis and Hemostasis Unit, Department of Hematology and Bone Marrow Transplantaion, Rambam Medical Center, Haifa, Israel. y_segal@ rambam.health.gov.il
    Rev Clin Exp Hematol 8:E4. 2004
    ..Numerous drugs are associated with thrombotic microangiopathy i.e., cyclosporine A, tacrolimus, cisplatin, bleomycin, gemcitabine. The clinical presentation, pathological mechanisms and therapeutic modalities are discussed...