Research Topics
| Zvi BentwichSummaryCountry: Israel Publications
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Detail Information
Publications
Concurrent infections that rise the HIV viral loadZvi Bentwich
Department of Immunology and Microbiology, Ben Gurion University Health Sciences Faculty, Beer Sheba, Israel
J HIV Ther 8:72-5. 2003..Further studies are urgently needed to clarify and further characterise the long-term effects of concurrent infections on the spread and progression of HIV/AIDS, and particularly on the immune response of the infected host...- Can worms defend our hearts? Chronic helminthic infections may attenuate the development of cardiovascular diseasesEli Magen
Ruth Ben An Institute of Clinical Immunology and AIDS Center, Kaplan Medical Center, Hebrew University Hadassah Medical School, Rehovot, Israel
Med Hypotheses 64:904-9. 2005..If the hypothesis that helminthic infections impact atherosclerosis is correct, it should be taken into consideration in atherosclerosis immunomodulation therapy and especially in the design of vaccines and vaccine trials... - Soluble chemokine CCR5 receptor is present in human plasmaAlexander Tsimanis
R Ben Ari Institute of Clinical Imunology and AIDS Center, Kaplan Medical Center, Hebrew University Hadassah Medical School, Rehovot, Israel
Immunol Lett 96:55-61. 2005..8+/-25.8 pg/ml) as in the sCCR5-negatives (77.6+/-11.0 pg/ml, P=0.0157). A significant positive correlation between plasma levels of sCCR5 and MIP-1beta was found (Fig. 4, r=0.8, P<0.0001)... - The helminth HIV connection: time to actZvi Bentwich
Center for Emerging Tropical Diseases and AIDS, Ben Gurion University Faculty of Health Sciences, Beer Sheba, Israel
AIDS 22:1611-4. 2008 - CD4 measurements in patients with HIV: are they feasible for poor settings?Zvi Bentwich
Hebrew University Medical School, Beer Sheba, Israel
PLoS Med 2:e214; quiz e254. 2005 - Treatment of intestinal helminths does not reduce plasma concentrations of HIV-1 RNA in coinfected Zambian adultsKayvon Modjarrad
Department of Epidemiology, University of Alabama, Birmingham, AL 35294 2170, USA
J Infect Dis 192:1277-83. 2005.... - CTLA-4 upregulation during HIV infection: association with anergy and possible target for therapeutic interventionQibin Leng
Ruth Ben-Ari Institute of Clinical Immunology and AIDS Center, Kaplan Medical Center, Hebrew University Hadassah Medical School, Rehovot 76100, Israel
AIDS 16:519-29. 2002..2) Increased levels of CTLA-4 may undermine immune responses and in the HAART-treated patient-immune reconstitution. (3) Blocking of CTLA-4 may offer a novel approach for immune-based therapy in HIV infection... - T-cell vaccination against anti-CD4 autoimmunity in HIV-1 infected patientsRivka Abulafia-Lapid
the Human Biology Research Center, Hadassah University Hospital, Ein Kerem, Jerusalem 91120, Israel
J Clin Virol 31:S48-54. 2004..Highly active antiretroviral therapy (HAART) is frequently associated with only partial restoration of CD4 T-cell levels. Autoimmunity to CD4 T-cells may account for the persistence of the CD4 T-cell lymphopenia in such cases... - Treatment of intestinal worms is associated with decreased HIV plasma viral loadDawit Wolday
Armauer Hansen Research Institute, Addis Ababa, Ethiopia
J Acquir Immune Defic Syndr 31:56-62. 2002..The results of the current study, if confirmed in a larger study, may have important implications for slowing disease progression and reducing risks of transmission... - Host background immunity and human immunodeficiency virus protective vaccines, a major consideration for vaccine efficacy in Africa and in developing countriesGadi Borkow
R. Ben-Ari Institute of Clinical Immunology and AIDS Center, Kaplan Medical Center, Hebrew University Hadassah Medical School, Rehovot, Israel
Clin Diagn Lab Immunol 9:505-7. 2002 - Chronic immune activation associated with chronic helminthic and human immunodeficiency virus infections: role of hyporesponsiveness and anergyGadi Borkow
Animal Scienes, Faculty of Agriculture, Hebrew University, Rehovot, Israel
Clin Microbiol Rev 17:1012-30, table of contents. 2004..The current knowledge of the mechanisms responsible for the generation of anergy by chronic immune activation is thoroughly reviewed... - Chronic parasite infections cause immune changes that could affect successful vaccinationGadi Borkow
Cupron Inc, Hameyasdim 44, Kfar Gibton, Israel
Trends Parasitol 24:243-5. 2008..Underscoring the importance of these issues, a recent report has highlighted several vaccination studies in which nematode-infected mice or pigs failed to mount efficient protective immune responses... - Neglected tropical diseases and HIV/AIDSPeter J Hotez
Lancet 368:1865-6. 2006 - Increased TGF-beta, Cbl-b and CTLA-4 levels and immunosuppression in association with chronic immune activationQibin Leng
R. Ben-Ari Institute of Clinical Immunology and AIDS Center, Kaplan Medical Center, Hebrew University Hadassah Medical School, Rehovot 76100, Israel
Int Immunol 18:637-44. 2006..We suggest that the higher levels of CTLA-4 and TGF-beta, both involved in the induction of Cbl-b, point at potential mechanisms underlying general and antigen-specific immune hyporesponsiveness in chronically infected individuals... - Serum immunoglobulin E levels in Israeli-Ethiopian children: environment and geneticsMona Iancovici Kidon
Allergy and Clinical Immunology Unit, Kaplan Medical Center, Rehovot, Israel
Isr Med Assoc J 7:799-802. 2005..Since 1984, several waves of Ethiopian immigrants have settled in Israel. On arrival they were found to be highly infected with intestinal parasites and to have increased serum immunoglobulin E and eosinophilia... - Generation of Th1 immune responses to inactivated, gp120-depleted HIV-1 in mice with a dominant Th2 biased immune profile via immunostimulatory [correction of imunostimulatory] oligonucleotides--relevance to AIDS vaccines in developing countriesMila Ayash-Rashkovsky
Ruth Ben-Ari Institute of Clinical Immunology and AIDS Center, Kaplan Medical Center, Hebrew University Hadassah Medical School, Rehovot 76100, Israel
Vaccine 20:2684-92. 2002..These findings strongly support the advisability of using CpG ODN as a Th1 inducing adjuvant when immunizing human populations with a strong pre-existent Th2 immune profile... - A novel small animal model for HIV-1 infectionMila Ayash-Rashkovsky
Hebrew University Hadassah Medical School, Jerusalem, Israel
FASEB J 19:1149-51. 2005..http://www.fasebj.org/cgi/doi/10.1096/fj.04-3185fje; doi:10.1096/fj.04-3185fje.)... - Enhanced HIV-1 specific immune response by CpG ODN and HIV-1 immunogen-pulsed dendritic cells confers protection in the Trimera murine model of HIV-1 infectionMila Ayash-Rashkovsky
Hebrew University Hadassah Medical School, Jerusalem, Israel
FASEB J 19:1152-4. 2005.... - Attenuated signaling associated with immune activation in HIV-1-infected individualsQibin Leng
R. Ben-Ari Institute of Clinical Immunology and AIDS Center, Kaplan Medical Center, Hebrew University Hadassah Medical School, 76100 Rehovot, Israel
Biochem Biophys Res Commun 298:464-7. 2002..Therefore, targeting immune negative modulators, such as Cbl-b, may serve as a novel approach for controlling HIV-1 disease progression... - Blocking of cell-free and cell-associated HIV-1 transmission through human cervix organ culture with UC781Ariela Zussman
R. Ben-Ari Institute of Clinical Immunology and AIDS Center, Kaplan Medical Center, Hebrew Uuniversity Hadassah Medical School, Rehovot, Israel
AIDS 17:653-61. 2003..CONCLUSIONS: Exposure of the cervix to UC781 results in blocking of subsequent HIV-1 transmission with no toxicity. Therefore, UC781 is an excellent candidate microbiocide... - Adenovirus expressing a bioluminescence reporter gene and cMAGI cell assay for the detection of HIV-1Gadi Borkow
Ruth Ben Ari Institute of Clinical Immunology and AIDS Center, Kaplan Medical Center, Hebrew University Hadassah Medical School, Rehovot 76100, Israel
Virus Genes 29:257-65. 2004..This method can also be used for discovery of novel anti HIV-1 drugs... - T-cell vaccination against anti-CD4 autoimmunity in HIV-1 subtypes B and C-infected patients--an extended open trialRivka Abulafia-Lapid
The Human Biology Research Center HBRC, Hadassah University Hospital, Ein Kerem, Jerusalem, Israel
Vaccine 23:2149-53. 2005..Despite highly active antiretroviral therapy (HAART), the persistence of CD4 T-cell lymphopenia may be associated with anti-CD4 autoimmunity. T-cell vaccination (TCV) may decrease such autoimmunity and elevate CD4 T-cell numbers...