Research Topics
| Sima HalevySummaryAffiliation: Ben-Gurion University of the Negev Country: Israel Publications
| Collaborators
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Detail Information
Publications
Leukocytoclastic vasculitis induced by low-dose methotrexate: in vitro evidence for an immunologic mechanismS Halevy
Department of Dermatology, Soroka, Medical Center, Faculty of Health Sciences, Ben Gurion University of the Negev, Beer Sheva, Israel
J Eur Acad Dermatol Venereol 10:81-5. 1998..The role of MTX in the induction of the vasculitis was further supported by a positive mast cell degranulation (MCD) test...- Acute generalized exanthematous pustulosis associated with polysensitivity to paracetamol and bromhexine: the diagnostic role of in vitro interferon-gamma release testS Halevy
Department of Dermatology, Soroka University Medical Center, Faculty of Health Sciences, Ben Gurion University of the Negev, Beer Sheva and Transplant Laboratory, Rabin Medical Center, Beilinson Campus, Petah Tikva, Israel
Clin Exp Dermatol 25:652-4. 2000..These findings suggest that the patient with AGEP may have polysensitivity to both drugs. The ELISA assessment also demonstrates the relevance of in vitro cytokine release tests in the investigation of such dermatoses... - The role of trace elements in psoriatic patients undergoing balneotherapy with Dead Sea bath saltS Halevy
Department of Dermatology, Soroka University Medical Center, Beer Sheva, Israel
Isr Med Assoc J 3:828-32. 2001..A beneficial effect was observed in patients with psoriasis vulgaris following balneotherapy with Dead Sea bath salt... - Clinical implications of in vitro drug-induced interferon gamma release from peripheral blood lymphocytes in cutaneous adverse drug reactionsSima Halevy
Department of Dermatology, Soroka University Medical Center, Faculty of Health Sciences, Ben Gurion University of the Negev, Beer Sheva, Israel
J Am Acad Dermatol 52:254-61. 2005..Drug-specific T cells are involved in the pathogenesis of cutaneous adverse drug reactions (CADRs)... - In vitro interferon-gamma release test in the diagnosis of drug-induced erythema nodosumSima Halevy
Department of Dermatology, Soroka University Medical Center, Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer Sheva, Israel
Isr Med Assoc J 6:59-60. 2004 - Profile of acute generalized exanthematous pustulosis in Israel during 2002-2005: results of the RegiSCAR StudyBatya Davidovici
Department of Dermatology, Soroka University Medical Center and Faculty of Health Sciences, Ben Gurion University of the Negev, Beer Sheva, Israel
Isr Med Assoc J 10:410-2. 2008..It is usually attributed to drugs, although other factors have also been implicated... - Acute generalized exanthematous pustulosisSima Halevy
Department of Dermatology and Venereology, Soroka University Medical Center, Ben Gurion University of the Negev, Beer Sheva 84101, Israel
Curr Opin Allergy Clin Immunol 9:322-8. 2009..The purpose of the present review is to update knowledge on acute generalized exanthematous pustulosis (AGEP) in terms of epidemiology, pathogenesis, cause, clinical features, diagnosis, and treatment... - Autoimmune progesterone dermatitis manifested as erythema annulare centrifugum: Confirmation of progesterone sensitivity by in vitro interferon-gamma releaseSima Halevy
Department of Dermatology, Soroka University Medical Center, Faculty of Health Sciences, Ben-Gurion University of the Negev, Israel
J Am Acad Dermatol 47:311-3. 2002..Sensitivity to progesterone was further confirmed in vitro by results of an interferon-gamma release test, which imply a possible role for T(H)1-type cytokines in autoimmune progesterone dermatitis... - Drug exposure and psoriasis vulgaris: case-control and case-crossover studiesArnon D Cohen
Department of Dermatology, Soroka University Medical Center, Israel
Acta Derm Venereol 85:299-303. 2005..9), beta-blockers (OR 9.9), dipyrone (OR 4.9) and NSAIDs (OR 2.1). Extensive psoriasis may be associated with intake of ACE inhibitors, NSAIDs or beta-blockers... - [Stevens-Johnson syndrome and toxic epidermal necrolysis--updates and innovations]Sima Halevy
Department of Dermatology and Venereology, Soroka Medical Center, Faculty of Health Sciences, Ben Gurion University of the Negev, Beer Sheba, Israel
Harefuah 149:186-90, 193. 2010..Founded on the genetic background of SJS/TEN, predictive tests can be used prior to starting high-risk medications. Treatment is still controversial, and further controlled studies are necessary... - Direct triggers for ulceration in patients with venous insufficiencyAvi Shai
Department of Dermatology, Soroka University Medical Center, Faculty of Health Sciences, Ben Gurion University of the Negev, Beer Sheva, Israel
Int J Dermatol 44:1006-9. 2005..The actual causes of venous ulcers, beyond the presence of venous insufficiency, are rarely referred to in the literature. This study evaluates the direct triggers for ulceration in patients with venous insufficiency... - Multiple drug allergy in patients with cutaneous adverse drug reactions diagnosed by in vitro drug-induced interferon-gamma releaseSima Halevy
Department of Dermatology, Soroka University Medical Center, Beer Sheva, Israel
Isr Med Assoc J 10:865-8. 2008..The pathogenesis may involve immediate-type or delayed-type hypersensitivity... - Is capturing the spider essential for the diagnosis of a spider bite? A clinical perspectiveBatya B Davidovici
Department of Dermatology, Soroka University Medical Center, Ben Gurion and University of the Negev, Beer-Sheva, Israel
J Am Acad Dermatol 58:349-50. 2008 - Acute generalized exanthematous pustulosis following a spider bite: report of 3 casesBatya B Davidovici
Department of Dermatology, Soroka University Medical Center, Ben-Gurion University of the Negev, Beer-Sheva, Israel
J Am Acad Dermatol 55:525-9. 2006..Three of 22 AGEP cases (13.6%), recruited by us as part of two prospective multinational studies, occurred 24 to 48 hours after a spider bite. We suggest that a spider bite is a possible trigger for AGEP... - Multiple agminated trichodiscomas in the earlobeArnon D Cohen
Department of Dermatology, Soroka University Medical Center, Beer-Sheva, Israel
J Am Acad Dermatol 49:729-30. 2003..In some cases, multiple trichodiscomas appear in association with fibrofolliculomas or acrochordons. We herein describe multiple agminated trichodiscomas in the earlobe... - [Necrotizing cutaneous vasculitis with massive gastrointestinal bleeding following naproxen treatment]Amir Horev
Department of Dermatology and Venereology, Soroka University Medical Center, Faculty of Health Sciences, Ben Gurion University of the Negev, Beer Sheba, srael
Harefuah 149:157-60, 195, 194. 2010..The possible etiological factors and the mechanisms involved in the induction of the vasculitis and the gastrointestinal bleeding are discussed... - Allopurinol is the most common cause of Stevens-Johnson syndrome and toxic epidermal necrolysis in Europe and IsraelSima Halevy
Department of Dermatology, Soroka University Medical Center, Ben Gurion University of the Negev, Beer Sheva, Israel
J Am Acad Dermatol 58:25-32. 2008..Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are rare severe cutaneous adverse reactions... - Coexistence of psoriatic arthritis and systemic lupus erythematosusAvital Avriel
Department of Internal Medicine D, Soroka University Hospital and Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer Sheva, Israel
Isr Med Assoc J 9:48-9. 2007 - [Acute generalized exanthematous pustulosis (AGEP) following intake of furosemide]Batya B Davidovici
Department of Dermatology and Institute of Pathology, Soroka University Medical Center, Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer Sheva, Israel
Harefuah 145:477-9, 552. 2006..CONCLUSION: We have described a rare case of typical AGEP most probably induced by furosemide... - Severe conjunctival and eyelid involvement in pemphigus vulgarisTova Lifshitz
Department of Ophthalmology, Soroka University Medical Center, Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer-Sheva, Israel
Int Ophthalmol 25:73-4. 2004..Severe ocular diseases without dermatological involvement may be present in PV patients... - Brownish reticulate maculopapular eruption on the flexuresEyal Peretz
Soroka University Medical Center, Ben-Gurion University of the Negev, Beer-Sheva, Israel
Arch Dermatol 139:381-6. 2003 - Pregnancy outcome in women with vitiligoAmir Horev
Department of Dermatology and Venereology, Soroka University Medical Center, Beer Sheva, Israel
Int J Dermatol 50:1083-5. 2011..Autoimmune disorders are more common among women and may be associated with adverse pregnancy outcomes, such as recurrent abortions, intrauterine growth restriction (IUGR), and pre-eclampsia... - Serum sickness-like reactionsJoseph Yerushalmi
Department of Dermatology, Soroka University Medical Center, Ben-Gurion University, Beer-Sheva, Israel
Cutis 69:395-7. 2002..This entity rarely has been discussed in the dermatologic literature. We describe the case of a 3-year-old girl with urticaria, fever, and arthralgia that appeared 8 days after starting cefaclor therapy for otitis media... - Stevens-Johnson syndrome and toxic epidermal necrolysis: assessment of medication risks with emphasis on recently marketed drugs. The EuroSCAR-studyMaja Mockenhaupt
Dokumentationszentrum schwerer Hautreaktionen, Department of Dermatology, University Medical Center, Freiburg, Germany
J Invest Dermatol 128:35-44. 2008..The use of such drugs as first-line therapies should be considered carefully, especially when safer alternative treatments exist. A number of widely used drugs did not show any risk for SJS and TEN... - A European study of HLA-B in Stevens-Johnson syndrome and toxic epidermal necrolysis related to five high-risk drugsChristine Lonjou
INSERM, U563 Paul Sabatier University III, Toulouse, France
Pharmacogenet Genomics 18:99-107. 2008..Recently, a strong association between carbamazepine and allopurinol induced SJS or TEN has been described with respectively, HLA-B*1502 and HLA-B*5801 in a Han Chinese population from Taiwan and other Asian countries...