R P Kirwan

Summary

Affiliation: University College Dublin
Country: Ireland

Publications

  1. ncbi Effect of cyclical mechanical stretch and exogenous transforming growth factor-beta1 on matrix metalloproteinase-2 activity in lamina cribrosa cells from the human optic nerve head
    Ruaidhri P Kirwan
    Institute of Ophthalmology, Mater Misericordiae University Hospital, Dublin, Ireland
    J Glaucoma 13:327-34. 2004
  2. ncbi Transforming growth factor-beta-regulated gene transcription and protein expression in human GFAP-negative lamina cribrosa cells
    Ruaidhri P Kirwan
    Conway Institute of Biomolecular and Biomedical Research, University College Dublin, Ireland
    Glia 52:309-24. 2005
  3. ncbi Influence of cyclical mechanical strain on extracellular matrix gene expression in human lamina cribrosa cells in vitro
    Ruaidhri P Kirwan
    Conway Institute of Biomolecular and Biomedical Research University College Dublin, Dublin, Ireland
    Mol Vis 11:798-810. 2005
  4. ncbi Superior orbital fissure syndrome in herpes zoster ophthalmicus
    R P Kirwan
    Department of Ophthalmic Surgery, St Vincent s University Hospital, Dublin 4, Ireland
    Ir J Med Sci 178:355-8. 2009
  5. ncbi Differential global and extra-cellular matrix focused gene expression patterns between normal and glaucomatous human lamina cribrosa cells
    Ruaidhri P Kirwan
    Conway Institute of Biomolecular and Biomedical Research, University College Dublin, Ireland
    Mol Vis 15:76-88. 2009
  6. ncbi Nd:YAG laser hyaloidotomy for valsalva pre-macular haemorrhage
    R P Kirwan
    Department of Ophthalmic Surgery, The Royal Victoria Eye and Ear Hospital, Adelaide Road, Dublin 2, Ireland
    Ir J Med Sci 180:749-52. 2011

Detail Information

Publications6

  1. ncbi Effect of cyclical mechanical stretch and exogenous transforming growth factor-beta1 on matrix metalloproteinase-2 activity in lamina cribrosa cells from the human optic nerve head
    Ruaidhri P Kirwan
    Institute of Ophthalmology, Mater Misericordiae University Hospital, Dublin, Ireland
    J Glaucoma 13:327-34. 2004
    ..the effect of cyclical mechanical stretch on TGF-beta1 mRNA synthesis, TGF-beta1 protein secretion, MMP-2 protein activity and (b). the effect of exogenous TGF-beta1 on MMP-2 protein activity in human lamina cribrosa cells in vitro...
  2. ncbi Transforming growth factor-beta-regulated gene transcription and protein expression in human GFAP-negative lamina cribrosa cells
    Ruaidhri P Kirwan
    Conway Institute of Biomolecular and Biomedical Research, University College Dublin, Ireland
    Glia 52:309-24. 2005
    ..In disease states such as POAG, the LC cell may represent an important pro-fibrotic cell type and an attractive target for novel therapeutic strategies...
  3. ncbi Influence of cyclical mechanical strain on extracellular matrix gene expression in human lamina cribrosa cells in vitro
    Ruaidhri P Kirwan
    Conway Institute of Biomolecular and Biomedical Research University College Dublin, Dublin, Ireland
    Mol Vis 11:798-810. 2005
    ..The authors examined global gene expression profiles in lamina cribrosa cells exposed to cyclical mechanical stretch, with an emphasis on ECM genes...
  4. ncbi Superior orbital fissure syndrome in herpes zoster ophthalmicus
    R P Kirwan
    Department of Ophthalmic Surgery, St Vincent s University Hospital, Dublin 4, Ireland
    Ir J Med Sci 178:355-8. 2009
    ..To report a case of superior orbital fissure syndrome (SOFS) in a patient with herpes zoster ophthalmicus (HZO)...
  5. ncbi Differential global and extra-cellular matrix focused gene expression patterns between normal and glaucomatous human lamina cribrosa cells
    Ruaidhri P Kirwan
    Conway Institute of Biomolecular and Biomedical Research, University College Dublin, Ireland
    Mol Vis 15:76-88. 2009
    ..We report the first study of global and ECM-focused gene transcription differentials between GFAP-negative lamina cribrosa (LC) cells from normal and POAG human donors...
  6. ncbi Nd:YAG laser hyaloidotomy for valsalva pre-macular haemorrhage
    R P Kirwan
    Department of Ophthalmic Surgery, The Royal Victoria Eye and Ear Hospital, Adelaide Road, Dublin 2, Ireland
    Ir J Med Sci 180:749-52. 2011
    ..To report a case of successful drainage of a large pre-macular haemorrhage using laser photo-disruption of the posterior hyaloid membrane...