Research Topics
| B BourkeSummaryAffiliation: University College Dublin Country: Ireland Publications
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Detail Information
Publications
Will treatment of Helicobacter pylori infection in childhood alter the risk of developing gastric cancer?Billy Bourke
Children s Research Centre, Our Lady s Hospital for Sick Children, Department of Paediatrics, University College Dublin, Crumlin, Ireland
Can J Gastroenterol 19:409-11. 2005..Therefore, except in groups with a high risk for development of gastric cancer (eg, Japanese or those with a strong positive family history of gastric cancer), a population-based test-and-treat policy is not justified...- Enteric campylobacter: purging its secrets?Ellen Crushell
FRCPI, Children s Research Centre, Our Lady s Hospital for Sick Children, Crumlin, Dublin 12, Ireland
Pediatr Res 55:3-12. 2004..However, recent completion of the genome sequence of Campylobacter jejuni promises to open up the Campylobacter research field with the prospect of developing novel therapeutic and preventive strategies... - Cochrane's epitaph for cisapride in childhood gastro-oesophageal refluxB Bourke
The Conway Institute for Biomolecular and Biomedical Research, Department of Paediatrics, University College Dublin, Ireland
Arch Dis Child 86:71-2. 2002 - Is Helicobacter pylori infection in childhood a risk factor for gastric cancer?C Imrie
Department of Paediatrics, University College Dublin and The Children's Research Centre, Our Lady's Hospital for Sick Children, Dublin, Ireland
Pediatrics 107:373-80. 2001..Based on our knowledge to date, we suggest that it is not indicated to treat all children with H pylori infection because of the risk of developing gastric cancer or to institute a screening and treatment program... - Campylobacter upsaliensis: waiting in the wingsB Bourke
Department of Paediatrics, University College Dublin, Ireland
Clin Microbiol Rev 11:440-9. 1998.... - Campylobacter upsaliensis exerts a cytolethal distending toxin effect on HeLa cells and T lymphocytesA Mooney
Children's Research Centre, Our Lady's Hospital for Sick Children and Department of Paediatrics, The Conway Institute of Biomolecular and Biomedical Research, University College Dublin, Crumlin, Dublin 12, Ireland
Microbiology 147:735-43. 2001..Using a combination of Annexin V/PI staining and TUNEL assay, cytodistended HeLa cells were shown to undergo apoptotic cell death. These data provide the first insights into the virulence mechanisms of this novel enteropathogen... - Limitations to carbon 13-labeled urea breath testing for Helicobacter pylori in infantsC Imrie
Department of Paediatrics, The Conway Institute of Molecular and Biomedical Research, University College, Dublin, Ireland
J Pediatr 139:734-7. 2001..Care is urged in interpreting one positive 13C-labeled urea breath test in children younger than 2 years... - The oral cavity in Crohn's diseaseS Pittock
Children's Research Centre, Our Lady's Hospital for Sick Children, and Department of Pediatrics, The Conway Institute for Biomolecular and Biomedical Science, University College Dublin, Ireland
J Pediatr 138:767-71. 2001..Oral manifestations of CD are common in children; therefore, expert oral examination may be useful during diagnostic evaluation of children with suspected inflammatory bowel disease... - Campylobacter jejuni cocultured with epithelial cells reduces surface capsular polysaccharide expressionN Corcionivoschi
The Children s Research Centre, Our Lady s Children s Hospital, Crumlin, Dublin 12, Ireland
Infect Immun 77:1959-67. 2009..C. jejuni alters its surface polysaccharides when cocultured with epithelial cells, suggesting the existence of a cross talk mechanism that modulates CPS expression during infection... - Basis of the superiority of cefoperazone amphotericin teicoplanin for isolating Campylobacter upsaliensis from stoolsC Byrne
Children's Research Centre, Our Lady's Hospital for Sick Children, Dublin 12, Ireland
J Clin Microbiol 39:2713-6. 2001..We conclude that although CAT is more suitable than mCCDA for the isolation of C. upsaliensis from stools, the superiority of CAT for detecting this organism is not accounted for by the antibiotic composition of the medium... - Probiotic colonization of the adherent mucus layer of HT29MTXE12 cells attenuates Campylobacter jejuni virulence propertiesAbofu Alemka
School of Medicine and Medical Science, Conway Institute, University College Dublin, Belfield, Dublin 4, Ireland
Infect Immun 78:2812-22. 2010..These results demonstrate the potential for E12 cells as a model of mucosal pathogenesis and provide a rationale for the further investigation of probiotics as prophylaxis against human campylobacteriosis... - Canadian Helicobacter Study Group Consensus Conference: Update on the approach to Helicobacter pylori infection in children and adolescents--an evidence-based evaluationBilly Bourke
Division of GI Nutrition, The Hospital for Sick Children, Department of Paediatrics, University of Toronto, Ontario, Canada
Can J Gastroenterol 19:399-408. 2005..pylori infection in children is 14 days; and H. pylori culture and antibiotic sensitivity testing should be made available to monitor population antibiotic resistance and manage treatment failures... - Random mutagenesis to identify novel Helicobacter mustelae virulence factorsTadhg O Cróinín
Children s Research Centre, Our Lady s Hospital for Sick Children, Crumlin, Dublin, Ireland
FEMS Immunol Med Microbiol 50:257-63. 2007..The development of a mutant library for a natural animal model of Helicobacter infection provides the opportunity to study in vivo the role of candidate Helicobacter virulence genes... - Age-specific incidence of Helicobacter pyloriMarion Rowland
University College Dublin School of Medicine and Medical Science, The Children's Research Centre, Dublin, Ireland
Gastroenterology 130:65-72; quiz 211. 2006..These findings have important implications for studies on the mode of transmission of infection...