Research Topics
| Fergal D MaloneSummaryAffiliation: Royal College of Surgeons in Ireland Country: Ireland Publications
| Collaborators
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Detail Information
Publications
Pregnancy loss rates after midtrimester amniocentesisKeith A Eddleman
Mount Sinai School of Medicine, New York, New York, USA
Obstet Gynecol 108:1067-72. 2006....- Nuchal translucency-based Down syndrome screening: barriers to implementationFergal D Malone
Department of Obstetrics and Gynaecology, Royal College of Surgeons in Ireland, Dublin, Ireland
Semin Perinatol 29:272-6. 2005.... - First-trimester septated cystic hygroma: prevalence, natural history, and pediatric outcomeFergal D Malone
Columbia University College of Physicians and Surgeons, New York, New York, USA
Obstet Gynecol 106:288-94. 2005..To estimate prevalence, natural history, and outcome of septated cystic hygroma in the first trimester in the general obstetric population, and to differentiate this finding from simple increased nuchal translucency... - First-trimester or second-trimester screening, or both, for Down's syndromeFergal D Malone
Columbia University College of Physicians and Surgeons, New York, USA
N Engl J Med 353:2001-11. 2005..It is uncertain how best to screen pregnant women for the presence of fetal Down's syndrome: to perform first-trimester screening, to perform second-trimester screening, or to use strategies incorporating measurements in both trimesters... - First-trimester nasal bone evaluation for aneuploidy in the general populationFergal D Malone
Columbia University College of Physicians and Surgeons, New York, New York, USA
Obstet Gynecol 104:1222-8. 2004..To evaluate the role of fetal nasal bone imaging at 10 3/7 to 13 6/7 weeks as a screening tool for aneuploidy, in a prospective multicenter trial... - Impact of maternal age on obstetric outcomeJane Cleary-Goldman
Columbia University Medical Center, New York, New York, USA
Obstet Gynecol 105:983-90. 2005..To estimate the effect of maternal age on obstetric outcomes... - Contingent screening for Down syndrome--results from the FaSTER trialHoward S Cuckle
Columbia University, New York, USA
Prenat Diagn 28:89-94. 2008..Comparison of contingent, step-wise and integrated screening policies... - Prediction of safe and successful vaginal twin birthFionnuala M Breathnach
Royal College of Surgeons in Ireland, Dublin, Ireland
Am J Obstet Gynecol 205:237.e1-7. 2011..The objective of the study was to establish predictors of vaginal twin birth and evaluate perinatal morbidity according to mode of delivery... - Nuchal translucency and the risk of congenital heart diseaseLynn L Simpson
Department of Obstetrics and Gynecology, Columbia University Medical Center, 622 West 168th Street, New York, NY 10032, USA
Obstet Gynecol 109:376-83. 2007..To estimate whether nuchal translucency assessment is a useful screening tool for major congenital heart disease (CHD) in the absence of aneuploidy... - Maternal thyroid hypofunction and pregnancy outcomeJane Cleary-Goldman
Columbia University Medical Center, New York, NY, USA
Obstet Gynecol 112:85-92. 2008..To estimate whether maternal thyroid hypofunction is associated with complications... - The effect of low body mass index on the development of gestational hypertension and preeclampsiaVictoria Belogolovkin
Mount Sinai School of Medicine, New York, NY 10029 6574, USA
J Matern Fetal Neonatal Med 20:509-13. 2007..To evaluate the relationship between low maternal body mass index (BMI) as calculated in the first trimester and the risk of preeclampsia and gestational hypertension... - Screening for fetal abnormalities with ultrasoundKaren Flood
Department of Obstetrics and Gynaecology, Royal College of Surgeons in Ireland, Rotunda Hospital, Dublin, Ireland
Curr Opin Obstet Gynecol 20:139-45. 2008..This review serves to explore literature published during the past year that has focussed on sonographic screening for fetal abnormalities... - Optimum timing for planned delivery of uncomplicated monochorionic and dichorionic twin pregnanciesFionnuala M Breathnach
Royal College of Surgeons in Ireland, Rotunda Hospital, Parnell Square, Dublin 1, Ireland
Obstet Gynecol 119:50-9. 2012..To determine the optimum timing for planned delivery of uncomplicated monochorionic and dichorionic twin pregnancies... - Screening for aneuploidy in first and second trimesters: is there an optimal paradigm?Fionnuala M Breathnach
Department of Obstetrics and Gynaecology, Royal College of Surgeons in Ireland, Rotunda Hospital, Dublin, Ireland
Curr Opin Obstet Gynecol 19:176-82. 2007..This review serves to explore the recent literature regarding aneuploidy screening in both first and second trimesters. We aim to construct a comparative analysis of a range of proposed strategies for screening for trisomy 21... - Obesity, obstetric complications and cesarean delivery rate--a population-based screening studyJoshua L Weiss
Division of Maternal Fetal Medicine, Columbia Presbytrian Medical Center, New York, NY 10032, USA
Am J Obstet Gynecol 190:1091-7. 2004..This study was undertaken to determine whether obesity is associated with obstetric complications and cesarean delivery... - Threatened abortion: A risk factor for poor pregnancy outcome, a population-based screening studyJoshua L Weiss
Columbia Presbyterian Medical Center, New York, NY, USA
Am J Obstet Gynecol 190:745-50. 2004..2), and placental abruption (odds ratio, 3.6). CONCLUSION: First-trimester vaginal bleeding is an independent risk factor for adverse obstetric outcome that is directly proportional to the amount of bleeding... - Placental cord insertion and birthweight discordance in twin pregnancies: results of the national prospective ESPRiT StudyEtaoin M Kent
Royal College of Surgeons in Ireland, Dublin, Ireland Rotunda Hospital, Dublin, Ireland
Am J Obstet Gynecol 205:376.e1-7. 2011..The purpose of this study was to evaluate the impact of noncentral placental cord insertion on birthweight discordance in twins... - First-trimester screening for aneuploidyKarlla W Brigatti
Division of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, Columbia University College of Physicians and Surgeons, Columbia Presbyterian Medical Center, 622 West 168th Street, PH16, New York, NY 10032, USA
Obstet Gynecol Clin North Am 31:v, 1-20. 2004..This article reviews the current status of first-trimester screening for Down syndrome and other aneuploidies and explores the issues related to implementing first-trimester screening into mainstream prenatal care in the United States... - The second trimester genetic sonogramFionnuala M Breathnach
Department of Obstetrics and Gynaecology, Royal College of Surgeons in Ireland, Rotunda Hospital, Dublin, Ireland
Am J Med Genet C Semin Med Genet 145:62-72. 2007..This review serves to describe the key components of the second trimester genetic sonogram and to illustrate how these markers are integrated into risk assessment for aneuploidy... - Screening for Down syndrome: practice patterns and knowledge of obstetricians and gynecologistsJane Cleary-Goldman
Division of Maternal Fetal Medicine, Columbia University Medical Center, New York, New York 10032, USA
Obstet Gynecol 107:11-7. 2006..To assess obstetricians' practice patterns and knowledge regarding screening for Down syndrome... - Early access to prenatal care: implications for racial disparity in perinatal mortalityAndrew J Healy
Columbia University Medical Center, 622 West 168th Street, PH 16, New York, NY 10032, USA
Obstet Gynecol 107:625-31. 2006..To investigate racial disparities in perinatal mortality in women with early access to prenatal care... - Platelet reactivity and pregnancy lossKaren Flood
Department of Obstetrics and Gynaecology, Royal College of Surgeons in Ireland, Dublin, Ireland
Am J Obstet Gynecol 203:281.e1-5. 2010..We sought to critically evaluate platelet function in recurrent miscarriage (RM)... - First-trimester sonographic screening for Down syndromeFergal D Malone
Division of Maternal Fetal Medicine, Department of Obstetrics and Gynecology, Columbia University College of Physicians and Surgeons, Columbia Presbyterian Medical Center, New York, New York 10032, USA
Obstet Gynecol 102:1066-79. 2003..Additionally, a detailed description of practical problems that might limit the implementation of this form of screening is presented... - First- and second-trimester screening: detection of aneuploidies other than Down syndromeFionnuala M Breathnach
Royal College of Surgeons in Ireland
Obstet Gynecol 110:651-7. 2007..To evaluate the performance of first- and second-trimester screening methods for the detection of aneuploidies other than Down syndrome... - Definition of intertwin birth weight discordanceFionnuala M Breathnach
Royal College of Surgeons in Ireland, UCD School of Medicine and Medical Science, University College Dublin, Ireland
Obstet Gynecol 118:94-103. 2011..To establish the level of birth weight discordance at which perinatal morbidity increases in monochorionic and dichorionic twin pregnancy... - Changing trends in peripartum hysterectomy over the last 4 decadesKaren M Flood
Department of Obstetrics and Gynaecology, Rotunda Hospital, Royal College of Surgeons in Ireland, Dublin, Ireland
Am J Obstet Gynecol 200:632.e1-6. 2009..The purpose of this study was to identify changing trends in peripartum hysterectomy (PH) in a single large obstetric population over the last 40 years... - Nuchal translucency-based screeningKarlla K Welch
Division of Maternal-Fetal, Department of Obstetrics and Gynecology, Columbia University College of Physicians and Surgeons, Columbia Presbiterian Medical Center, New York, New York, USA
Clin Obstet Gynecol 46:909-22. 2003 - Radiofrequency ablation in a monochorionic twin discordant for fetal anomaliesTracy Shevell
Division of Maternal Fetal Medicine, Department of Obstetrics and Gynecology, Columbia Presbyterian Medical Center, Columbia University, New York, NY 10032, USA
Am J Obstet Gynecol 190:575-6. 2004..We report a case in which radiofrequency ablation was used to selectively reduce a monochorionic twin discordant for an abnormality... - Prevention of preterm birthKaren Flood
Royal College of Surgeons in Ireland, Department of Obstetrics and Gynaecology, Dublin, Ireland
Semin Fetal Neonatal Med 17:58-63. 2012..Widely accepted strategies include cervical cerclage, progesterone and dedicated clinics. However, more research is needed to explore the role of antibiotics and anti-inflammatory treatments in the prevention of this complex problem... - Maternal complications associated with multiple pregnancyPatricia C Devine
New York Presbyterian Hospital, Columbia University, College of Physicians and Surgeons, New York, New York 10023, USA
Clin Obstet Gynecol 47:227-36. 2004 - Comparison of serum markers in first-trimester down syndrome screeningJacob A Canick
Women and Infants Hospital and Brown Medical School, Providence, Rhode Island, USA
Obstet Gynecol 108:1192-9. 2006..level of evidence: ii-2... - Quad screen as a predictor of adverse pregnancy outcomeLorraine Dugoff
Department of Obstetrics and Gynecology, University of Colorado Health Sciences Center, Denver, Colorado 80262, USA
Obstet Gynecol 106:260-7. 2005.... - Sequential pathways of testing after first-trimester screening for trisomy 21Fergal D Malone
Obstet Gynecol 105:438; author reply 438-9. 2005 - Individualized norms of optimal fetal growth: fetal growth potentialRadek Bukowski
Department of Obstetrics and Gynecology, University of Texas Medical Branch, Galveston, Texas 77555, USA
Obstet Gynecol 111:1065-76. 2008..To demonstrate that individualized optimal fetal growth norms, accounting for physiologic and pathologic determinants of fetal growth, better identify normal and abnormal outcomes of pregnancy than existing methods... - Variability in thyroid-stimulating hormone suppression by human chorionic [corrected] gonadotropin during early pregnancyJames E Haddow
The Warren Alpert Medical School of Brown University, Providence, Rhode Island 02903, USA
J Clin Endocrinol Metab 93:3341-7. 2008..The objective of the study was to further explore relationships between human chorionic gonadotropin (hCG), TSH, and free T4 in pregnant women at 11 through 18 wk gestation... - The use of nuchal translucency in contemporary obstetric practiceSoha Said
Department of Obstetrics and Gynecology, Royal College of Surgeons in Ireland, Rotunda Hospital, Parnell Square, Dublin 1, Republic of Ireland
Clin Obstet Gynecol 51:37-47. 2008..This method can also identify more than 90% of fetuses with trisomies 18 and 13, Turner syndrome, and triploidy for a screen-positive rate of 1%... - Prediction of patient-specific risk for fetal loss using maternal characteristics and first- and second-trimester maternal serum Down syndrome markersLorraine Dugoff
Department of Obstetrics and Gynecology, University of Colorado at Denver Health Sciences Center, Aurora, CO, USA
Am J Obstet Gynecol 199:290.e1-6. 2008..To develop and evaluate a method of estimating patient-specific risk for fetal loss by combining maternal characteristics with serum markers... - Down syndrome screening in twinsMelissa C Bush
Division of Maternal Fetal Medicine, Department of Obstetrics and Gynecology, University of California, Irvine, 101 The City Drive, Orange, CA 92868, USA
Clin Perinatol 32:373-86, vi. 2005..Patients accepting screening should be aware of all options should a diagnosis of fetal aneuploidy be confirmed, including pregnancy continuation, termination of the entire pregnancy, and selective termination of an aneuploid fetus... - First-trimester maternal serum PAPP-A and free-beta subunit human chorionic gonadotropin concentrations and nuchal translucency are associated with obstetric complications: a population-based screening study (the FASTER Trial)Lorraine Dugoff
Department of Gynecology and Obstetrics, University of Colorado Health Sciences Center, Denver, CO, USA
Am J Obstet Gynecol 191:1446-51. 2004..Low free-beta subunit human chorionic gonadotropin levels and large nuchal translucency were both associated with early fetal loss... - Stability of first- and second-trimester serum markers after storage and shipmentGeralyn M Lambert-Messerlian
Department of Pathology and Laboratory Medicine, Brown University and Women and Infants Hospital, Providence, Rhode Island 02903, USA
Prenat Diagn 26:17-21. 2006..The purpose of this study was to examine the levels of first- and second-trimester maternal serum markers used in Down syndrome screening in relation to the time between sample collection and arrival at the laboratory... - First- and second-trimester evaluation of risk for Down syndromeRobert H Ball
Department of Obstetrics, Gynecology, and Reproductive Sciences, UCSF, San Francisco, CA 94143 0132, USA
Obstet Gynecol 110:10-7. 2007..To investigate the differences in costs and outcomes of Down syndrome screening using data from the First and Second Trimester Evaluation of Risk (FASTER) Trial... - Is there a nuchal translucency millimeter measurement above which there is no added benefit from first trimester serum screening?Christine H Comstock
Division of Fetal Imaging, Department of Obstetrics and Gynecology, William Beaumont Hospital, Royal Oak, MI 48073, USA
Am J Obstet Gynecol 195:843-7. 2006..The purpose of this study was to evaluate whether there is a nuchal translucency (NT) measurement, independent of gestational age, above which immediate diagnostic testing should be offered without waiting for first trimester serum markers... - First- and second-trimester thyroid hormone reference data in pregnant women: a FaSTER (First- and Second-Trimester Evaluation of Risk for aneuploidy) Research Consortium studyGeralyn Lambert-Messerlian
Warren Alpert Medical School of Brown University, Providence, RI, USA
Am J Obstet Gynecol 199:62.e1-6. 2008..The purpose of this study was to calculate first and second trimester reference ranges and within-woman correlations for TSH, free T4, and thyroid antibodies... - A double-blinded, randomized controlled trial of oxytocin at the beginning versus the end of the third stage of labor for prevention of postpartum hemorrhageWarner K Huh
Division of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, Tufts University School of Medicine/Tufts-New England Medical Center, Boston, Mass. 02111, USA
Gynecol Obstet Invest 58:72-6. 2004..14.8%) was significantly lowered with oxytocin following placental delivery (p = 0.049). CONCLUSIONS: In our study, postpartum hemorrhage was less frequent when oxytocin administration was delayed until after placenta delivery... - First trimester uterine artery Doppler abnormalities predict subsequent intrauterine growth restrictionLorraine Dugoff
Department of Obstetric and Gynecology, University of Colorado Health Sciences Center, Denver, CO, USA
Am J Obstet Gynecol 193:1208-12. 2005..5 times more likely to have IUGR (95% CI 1.6-18.7). There was no significant relationship between notching and IUGR. CONCLUSION: Elevated first trimester uterine artery mean RI is significantly associated with IUGR... - Procedure-related complications of amniocentesis and chorionic villus samplingFergal D Malone
Obstet Gynecol 110:1425-6; author reply 1426. 2007 - Assisted reproductive technology and pregnancy outcomeTracy Shevell
Division of Maternal Fetal Medicine, Whittingham Pavilion, Stamford Hospital, 30 Shelburne Road, Stamford, CT 06904, USA
Obstet Gynecol 106:1039-45. 2005..To determine whether the use of assisted reproductive technology (ART) is associated with an increase in chromosomal abnormalities, fetal malformations, or adverse pregnancy outcomes... - The contribution of birth defects to preterm birth and low birth weightSiobhan M Dolan
Albert Einstein College of Medicine Montefiore Medical Center, 1300 Morris Park Avenue, Bronx, NY 10461, USA
Obstet Gynecol 110:318-24. 2007..To assess the impact of birth defects on preterm birth and low birth weight... - Proteomic analysis of maternal serum in down syndrome: identification of novel protein biomarkersSrinivasa R Nagalla
Department of Pediatrics, Oregon Health and Science University, Portland, Oregon 97239, USA
J Proteome Res 6:1245-57. 2007..Further characterization and quantification of these markers in a larger cohort of subjects may provide the basis for new tests for improved DS screening... - Fetal growth in early pregnancy and risk of delivering low birth weight infant: prospective cohort studyRadek Bukowski
Department of Obstetrics and Gynecology, University of Texas Medical Branch, 301 University Boulevard, Galveston, TX 77555, USA
BMJ 334:836. 2007..To determine if first trimester fetal growth is associated with birth weight, duration of pregnancy, and the risk of delivering a small for gestational age infant... - Human sexual size dimorphism in early pregnancyRadek Bukowski
Department of Obstetrics and Gynecology, University of Texas Medical Branch, Galveston, TX 77555 1062, USA
Am J Epidemiol 165:1216-8. 2007..009; spontaneous conception = 120 g, 95% CI: 107, 132, p < 0.00001). These data demonstrate that human fetuses exhibit sexual size dimorphism in the first trimester of pregnancy... - Sequential first- and second-trimester TSH, free thyroxine, and thyroid antibody measurements in women with known hypothyroidism: a FaSTER trial studyMonica R McClain
Warren Alpert Medical School, Brown University, Providence, RI 02903, USA
Am J Obstet Gynecol 199:129.e1-6. 2008..The purpose of this study was to examine how closely hypothyroidism management in the general pregnancy population satisfies recently issued guidelines and to determine whether improvements are indicated...