Research Topics
Species | R M DwyerSummaryAffiliation: National University of Ireland Country: Ireland Publications
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Detail Information
Publications
Dysregulated miR-183 inhibits migration in breast cancer cellsAoife J Lowery
Department of Surgery, National University of Ireland, Galway, Ireland
BMC Cancer 10:502. 2010..MiR-183 is located on chromosome 7q32 and is part of a miRNA family which are dysregulated in numerous cancers. The aims of this study were to further examine the expression and functional role of miR-183 in breast cancer...
Mesenchymal stem cells and cancer: tumor-specific delivery vehicles or therapeutic targets?R M Dwyer
Division of Surgery, School of Medicine, National University of Ireland, Galway, Ireland
Hum Gene Ther 21:1506-12. 2010..Elucidation of any potential negative effect of MSCs in the tumor setting will support development of protocols to minimize these effects while taking full advantage of the remarkable tumor-homing capacity of these cells...
Advances in mesenchymal stem cell-mediated gene therapy for cancerRoisin M Dwyer
Division of Surgery, School of Medicine, Clinical Science Institute, National University of Ireland Galway, Galway, Ireland
Stem Cell Res Ther 1:25. 2010....
Potential role of mesenchymal stem cells (MSCs) in the breast tumour microenvironment: stimulation of epithelial to mesenchymal transition (EMT)F T Martin
Department of Surgery, National University of Ireland Galway, Galway, Ireland
Breast Cancer Res Treat 124:317-26. 2010..Breast cancer cell morphology and growth pattern also altered in response to MSCs. MSCs may promote breast cancer metastasis through facilitation of EMT...
Relationship between CCL5 and transforming growth factor-?1 (TGF?1) in breast cancerM C Hartmann
Division of Surgery, School of Medicine, National University of Ireland Galway, Ireland
Eur J Cancer 47:1669-75. 2011..Hormonal control of CCL5, and a potential relationship with TGF?1, was also investigated...
Monocyte chemotactic protein-1 secreted by primary breast tumors stimulates migration of mesenchymal stem cellsR M Dwyer
Department of Surgery, National University of Ireland, Galway, Ireland
Clin Cancer Res 13:5020-7. 2007..This study is aimed at investigating factors mediating homing of human MSCs to breast cancer primary cultures and cell lines in vitro and in vivo...
