Research Topics
| Phillipe TaupinSummaryAffiliation: Dublin City University Country: Ireland Publications
|
Detail Information
Publications
Brevetoxin derivative compounds for stimulating neuronal growth: University of North Carolina at Wilmington: WO2008131411 Phillipe Taupin
Dublin City University, School of Biotechnology, Glasnevin, Dublin 9, Ireland
Expert Opin Ther Pat 19:269-74. 2009....
Apigenin and related compounds stimulate adult neurogenesis. Mars, Inc., the Salk Institute for Biological Studies: WO2008147483Philippe Taupin
Dublin City University, School of Biotechnology, Glasnevin, Dublin 9, Ireland
Expert Opin Ther Pat 19:523-7. 2009....
Neurogenic drugs and compoundsPhilippe Taupin
School of Biotechnology, Dublin City University, Dublin, Ireland
Recent Pat CNS Drug Discov 5:253-7. 2010..Here, we reviewed and discussed recent patents on neurogenic drugs and compounds, particularly nootropic agents and apigenin and related compounds...
Cell lines expressing mutant FX proteins to generate proteins with reduced rate of fucosylation: WO2010/141478Philippe Taupin
Dublin City University, School of Biotechnology, Glasnevin, Dublin 9, Ireland
Expert Opin Ther Pat 21:1143-6. 2011..The application (WO 2010/141478) is in the field of glycobiology and deals with the synthesis of recombinant proteins with a reduced rate of fucosylation...
Ex vivo fucosylation of stem cells to improve engraftment: WO2004094619Philippe Taupin
Dublin City University, School of Biotechnology, Glasnevin, Dublin, Ireland
Expert Opin Ther Pat 20:1265-9. 2010..The application is in the field of haematopoietic stem cell (HSC) and umbilical cord blood (CB) transplantation...
Transplantation of two populations of stem cells to improve engraftment: WO2008060932Philippe Taupin
Dublin City University, School of Biotechnology, Glasnevin, Dublin 9, Ireland
Expert Opin Ther Pat 20:1259-63. 2010..The application is in the field of haematopoietic stem cells (HSCs) and cellular therapy...
Thirteen compounds promoting oligodendrocyte progenitor cell differentiation and remyelination for treating multiple sclerosis: WO2010054307Philippe Taupin
Dublin City University, School of Biotechnology, Glasnevin, Dublin 9, Ireland
Expert Opin Ther Pat 20:1767-73. 2010..Objective: It aims at identifying and characterizing compounds and molecules that promote the differentiation of oligodendrocyte progenitor cells and remyelination of the nervous system...
Antibodies against CD20 (rituximab) for treating multiple sclerosis: US20100233121Philippe Taupin
Dublin City University, School of Biotechnology, Glasnevin, Dublin 9, Ireland
Expert Opin Ther Pat 21:111-4. 2011..The application is in the field of medication and treatment for MS...
Neurogenesis, NSCs, pathogenesis and therapies for Alzheimer's diseasePhilippe Taupin
School of Biotechnology, Dublin City University, Glasnevin, Dublin 9, Ireland
Front Biosci (Schol Ed) 3:178-90. 2011..We will review and discuss the potential of adult NSCs for the treatment of AD and their contribution to the pathogenesis of the disease, as well as the development of novel drugs and therapies for treating AD...
Neurogenic drugs and compounds to treat CNS diseases and disordersPhilippe Taupin
School of Biotechnology, Dublin City University, Glasnevin, Dublin 9, Ireland
Cent Nerv Syst Agents Med Chem 11:35-7. 2011....
Chimeric proteins comprising the constant region of immunoglobulins for treating hemophilia B (WO2005001025)Philippe Taupin
Dublin City University, School of Biotechnology, Glasnevin, Dublin 9, Ireland
Expert Opin Ther Pat 21:967-70. 2011..The application claims the methods of making recombinant chimeric proteins comprising of one biologically active molecule fused to the Fc region of the heavy chain(s) of immunoglobulins and their use for therapy...
Modulation of GDP-fucose level for generating proteins with reduced rate of fucosylation (WO2010141855)Philippe Taupin
Dublin City University, School of Biotechnology, Glasnevin, Dublin 9, Ireland
Expert Opin Ther Pat 21:1497-9. 2011..The application (WO2010141855) is in the field of glycobiology, and involves the control of the rate of fucosylation of proteins by exogenous factors...
Parthenogenetically activated human oocytes and parthenogenetic embryonic stem cells: US20100233143Philippe Taupin
Dublin City University, School of Biotechnology, Glasnevin, Dublin, Ireland
Expert Opin Ther Pat 21:1281-3. 2011..The application (US20100233143) is in the field of embryonic stems cells (ESCs) and the generation of ESCs from parthenogenetically activated human oocytes...
Very small embryonic-like stem cells for regenerative medicine: WO2010039241Philippe Taupin
Dublin City University, Glasnevin, Dublin, Ireland
Expert Opin Ther Pat 20:1103-6. 2010..The application is in the field of stem cells and regenerative medicine...
A dual activity of ROS and oxidative stress on adult neurogenesis and Alzheimer's diseasePhilippe Taupin
Dublin City University, Glasnevin, Ireland
Cent Nerv Syst Agents Med Chem 10:16-21. 2010..Antioxidant may be used to reduce the deleterious activity of ROS, particularly on newly generated neuronal cells of the adult brain, potentially delaying the development of AD and promoting the regenerative capacity of the adult brain...
A simple and direct pre-embedding technique for ultrastructure of scarce biological specimensP Taupin
Fighting Blindness Vision Research Institute, National Institute for Cellular Biotechnology and Dublin City University, Dublin 9, Glasnevin, Ireland
Biotech Histochem 83:253-7. 2008..The ability to pre-embed scarce biological specimens efficiently and reproducibly provides a valuable way to study and characterize cytological tissues such as biopsies or cystic and amniotic fluid cells...
Adult neural stem cells for the treatment of neuroinflammation. Fondazione Centro San Raffaele del Monte Tabor: WO2007015173Philippe Taupin
Dublin City University, School of Biotechnology, Glasnevin, Dublin 9, Ireland
Expert Opin Ther Pat 19:373-6. 2009..The application is in the field of stem cells and their therapeutic application for the treatment of inflammation...
Human neural progenitor and stem cells: US20080107633A1Philippe Taupin
Dublin City University, School of Biotechnology, Glasnevin, Dublin 9, Ireland
Expert Opin Ther Pat 19:377-80. 2009..The application is in the field of neural stem cells (NSCs) and cellular therapy...
Cryopreservation of early postmitotic neuronal cells in culturePhilippe Taupin
Dublin City University, School of Biotechnology, Glasnevin, Dublin 9, Ireland
Expert Opin Ther Pat 19:265-8. 2009..The application is in the field of embryonic stem cells (ESCs) and the cryopreservation of neuronal cells in culture...
Fourteen compounds and their derivatives for the treatment of diseases and injuries characterized by reduced neurogenesis and neurodegeneration. Neuronascent, Inc.: WO2007035722Philippe Taupin
Dublin City University, School of Biotechnology, Glasnevin, Dublin 9, Ireland
Expert Opin Ther Pat 19:541-7. 2009....
Adult periodontal-derived neural progenitor and stem cells. Institut fur Molekulare Diagnostik und Innovative Therapie: WO2008031451Philippe Taupin
Dublin City University, School of Biotechnology, Glasnevin, Dublin 9, Ireland
Expert Opin Ther Pat 19:715-9. 2009..Periodontal tissue can be harvested with minimal invasive procedures from the patient himself, providing a promising source of tissue for NSC-based therapy and autologous transplantation...
Nootropic agents stimulate neurogenesis. Brain Cells, Inc.: WO2007104035Philippe Taupin
Dublin City University, School of Biotechnology, Glasnevin, Dublin 9, Ireland
Expert Opin Ther Pat 19:727-30. 2009..The application claims the use of nootropic agents for their neurogenic activity and for the treatment of neurological diseases, disorders and injuries, by stimulating or increasing the generation of neuronal cells in the adult brain...
Adult neurogenesis, neural stem cells and Alzheimer's disease: developments, limitations, problems and promisesPhilippe Taupin
School of Biotechnology, Dublin City University, Glasnevin, Dublin 9, Ireland
Curr Alzheimer Res 6:461-70. 2009..Limitations in protocols to establish homogeneous populations of neural progenitor and stem cells and niches for neurogenesis need to be resolved and unlocked, for the full potential of adult NSCs to be realized for therapy...
Adult neurogenesis, neuroinflammation and therapeutic potential of adult neural stem cellsPhilippe Taupin
Fighting Blindness Vision Research Institute, National Institute for Cellular Biotechnology, Glasnevin Dublin 9
Int J Med Sci 5:127-32. 2008..We will discuss the role and contribution of neuroinflammation and adult neurogenesis to neurological diseases and disorders, and for the therapeutic potential of adult NSCs...
