Research Topics
Genomes and GenesSpecies | Amar AghaSummaryAffiliation: Beaumont Hospital Country: Ireland Publications
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Detail Information
Publications
Modulation of glucocorticoid metabolism by the growth hormone - IGF-1 axisAmar Agha
Department of Endocrinology, St Bartholomew s Hospital William Harvey Research Institute, Queen Mary University of London, UK
Clin Endocrinol (Oxf) 66:459-65. 2007....
Hypopituitarism following traumatic brain injury (TBI)Amar Agha
Divisions of Endocrinology and Neurosurgery, Beaumont Hospital and the RCSI Medical School, Dublin, Ireland
Br J Neurosurg 21:210-6. 2007....
The natural history of post-traumatic hypopituitarism: implications for assessment and treatmentAmar Agha
Academic Department of Endocrinology, Beaumont Hospital, Dublin, Ireland
Am J Med 118:1416. 2005..We attempted to define the natural history of post-traumatic hypopituitarism to devise guidelines for the optimal timing of patients' assessment and hormone replacement...
The natural history of surgically treated but radiotherapy-naïve nonfunctioning pituitary adenomasEoin P O'Sullivan
Division of Neuro endocrinology, Beaumont Hospital and the RCSI Medical School, Dublin, Ireland
Clin Endocrinol (Oxf) 71:709-14. 2009..We aimed to define the natural history of a large, mainly unselected cohort with surgically treated, radiotherapy (RT)-naïve NFPAs and to try to identify predictors of recurrence/regrowth...
Hypothalamic-pituitary dysfunction after irradiation of nonpituitary brain tumors in adultsAmar Agha
Department of Endocrinology, Beaumont Hospital, Beaumont Road, Dublin 9, Ireland
J Clin Endocrinol Metab 90:6355-60. 2005....
Spontaneous recovery from posttraumatic hypopituitarismAmar Agha
From the Department of Endocrinology, Beaumont Hospital, Dublin, Ireland
Am J Phys Med Rehabil 84:381-5. 2005....
The interaction between growth hormone and the thyroid axis in hypopituitary patientsLucy Ann Behan
Academic Department of Endocrinology, Beaumont Hospital, Dublin, Ireland
Clin Endocrinol (Oxf) 74:281-8. 2011....
Identifying coronary artery disease in men with type 2 diabetes: osteoprotegerin, pulse wave velocity, and other biomarkers of cardiovascular riskColin Davenport
Department of Diabetes and Endocrinology, Royal College of Surgeons in Ireland Medical School, Beaumont Hospital, Dublin, Ireland
J Hypertens 29:2469-75. 2011..The second aim was to compare OPG levels in patients with microvascular complications (microalbuminuria) against those with established CAD...
Optimizing glucocorticoid replacement therapy in severely adrenocorticotropin-deficient hypopituitary male patientsLucy Ann Behan
Division of Endocrinology, Beaumont Hospital and RCSI Medical School, Dublin, Ireland
Clin Endocrinol (Oxf) 75:505-13. 2011..Management strategies vary from treatment with 15-30 mg or higher in daily divided doses, reflecting the paucity of prospective data on the adequacy of different glucocorticoid regimens...
Anterior pituitary dysfunction following traumatic brain injury (TBI)Amar Agha
Department of Endocrinology, Division of Endocrinology and Diabetes, Beaumont Hospital and the RCSI Medical School, Dublin, Ireland
Clin Endocrinol (Oxf) 64:481-8. 2006....
Endocrine consequences of adult traumatic brain injuryLucy Ann Behan
Division of Endocrinology, Beaumont Hospital and the RCSI Medical School, Dublin, Ireland
Horm Res 68:18-21. 2007....
The natural history of post-traumatic neurohypophysial dysfunctionAmar Agha
Academic Department of Endocrinology, Beaumont Hospital, Dublin, Ireland
Eur J Endocrinol 152:371-7. 2005..Most cases recover completely but there is an appreciable frequency of long-term DI which can be subtle and should be recognized and managed appropriately...
Conventional glucocorticoid replacement overtreats adult hypopituitary patients with partial ACTH deficiencyAmar Agha
Department of Endocrinology, Beaumont Hospital, Dublin, Ireland
Clin Endocrinol (Oxf) 60:688-93. 2004..The results suggest that current conventional glucocorticoid replacement overtreats patients with partial ACTH deficiency under normal unstressed physiological conditions...
Neuroendocrine dysfunction in the acute phase of traumatic brain injuryAmar Agha
Academic Department of Endocrinology, Beaumount Hospital, Dublin, Ireland
Clin Endocrinol (Oxf) 60:584-91. 2004..CONCLUSION: Our data show that post-traumatic neuroendocrine abnormalities occur early and with high frequency, which may have significant implications for recovery and rehabilitation of TBI patients...
Unmasking of central hypothyroidism following growth hormone replacement in adult hypopituitary patientsAmar Agha
William Harvey Research Institute, Queen Mary University of London, London, UK
Clin Endocrinol (Oxf) 66:72-7. 2007..The effect of GH replacement on thyroid function in hypopituitary patients has hitherto been studied in small groups of children and adults with conflicting results...
Small-cell lung cancer presenting as diabetes insipidus and Cushing's syndromeAmar Agha
Department of Endocrinology, Beaumont Hospital, Dublin, Ireland
Pituitary 8:105-7. 2005..This case is a remarkable example of the complex metabolic endocrine manifestations of small-cell lung cancer...
High risk of hypogonadism after traumatic brain injury: clinical implicationsAmar Agha
Academic Division of Endocrinology and Diabetes, Beaumont Hospital and RCSI Medical School, Dublin, Ireland
Pituitary 8:245-9. 2005....
Clinical insights into the safety and utility of the insulin tolerance test (ITT) in the assessment of the hypothalamo-pituitary-adrenal axisFrancis M Finucane
Academic Department of Endocrinology, Beaumont Hospital and the RCSI Medical School, Dublin, Ireland
Clin Endocrinol (Oxf) 69:603-7. 2008..Whether basal cortisol concentration can reliably predict an adequate adrenal response to hypoglycaemia remains to be determined...
Osteoprotegerin and biomarkers of vascular inflammation in type 2 diabetesEoin P O'Sullivan
Department of Diabetes, Royal College of Surgeons in Ireland Medical School, Beaumont Hospital, Dublin, Ireland
Diabetes Metab Res Rev 26:496-502. 2010....
Central pontine myelinolysis complicating treatment of the hyperglycaemic hyperosmolar stateGrainne O'Malley
Division of Endocrinology and Diabetes, Beaumont Hospital, Dublin, Ireland
Ann Clin Biochem 45:440-3. 2008....
Anterior pituitary dysfunction in survivors of traumatic brain injuryAmar Agha
Academic Department of Endocrinology, Beaumont Hospital, Dublin 9, Ireland
J Clin Endocrinol Metab 89:4929-36. 2004..Hypopituitarism is a treatable cause of morbidity after TBI. In addition to conventional pituitary hormone replacement, the potential of GH treatment to enhance recovery needs to be examined in a prospective study...
The long-term predictive accuracy of the short synacthen (corticotropin) stimulation test for assessment of the hypothalamic-pituitary-adrenal axisAmar Agha
Division of Medical Sciences, University of Birmingham, Queen Elizabeth Hospital, Edgbaston, Birmingham B15 2TH, United Kingdom
J Clin Endocrinol Metab 91:43-7. 2006..The high-dose short Synacthen (corticotropin) test (SST) is widely used to investigate suspected secondary adrenal insufficiency, but concern remains about falsely reassuring results...
Hypothalamopituitary dysfunction following traumatic brain injury and aneurysmal subarachnoid hemorrhage: a systematic reviewHarald Jorn Schneider
Neuroendocrinology Group, Max Planck Institute of Psychiatry, Munich, Germany
JAMA 298:1429-38. 2007..This sequela is a potentially serious but treatable complication of brain injury...
Posterior pituitary dysfunction after traumatic brain injuryAmar Agha
Academic Department of Endocrinology, Beaumont Hospital, Dublin 9, Ireland
J Clin Endocrinol Metab 89:5987-92. 2004..Identification of patients with partial posttraumatic DI is important because appropriate treatment may reduce morbidity and optimize the potential for recovery...
Aneurysmal subarachnoid hemorrhageMark Sherlock
N Engl J Med 354:1755-7; author reply 1755-7. 2006
