Zahra Hajihassan

Summary

Affiliation: University of Tehran
Country: Iran

Publications

  1. ncbi Studies on the binding affinity of anticancer drug mitoxantrone to chromatin, DNA and histone proteins
    Zahra Hajihassan
    Department of Biochemistry, Institute of Biochemistry and Biophysics, University of Tehran, Tehran, Iran
    J Biomed Sci 16:31. 2009
  2. ncbi Interaction of mitoxantrone, as an anticancer drug, with chromatin proteins, core histones and H1, in solution
    Zahra Hajihassan
    Department of Biochemistry, Institute of Biochemistry and Biophysics, University of Tehran, Tehran, Iran
    Int J Biol Macromol 48:87-92. 2011
  3. ncbi The effect of vinca alkaloid anticancer drug, vinorelbine, on chromatin and histone proteins in solution
    Azra Rabbani-Chadegani
    Department of Biochemistry, Institute of Biochemistry and Biophysics, University of Tehran, Tehran, Iran
    Eur J Pharmacol 613:34-8. 2009
  4. ncbi The effect of mitoxantrone as an anticancer drug on hepatocytes nuclei and chromatin: Selective release of histone proteins
    Zahra Hajihassan
    Department of Biochemistry, Institute of Biochemistry and Biophysics, University of Tehran, Tehran, Iran
    Indian J Pharmacol 43:187-91. 2011

Detail Information

Publications4

  1. ncbi Studies on the binding affinity of anticancer drug mitoxantrone to chromatin, DNA and histone proteins
    Zahra Hajihassan
    Department of Biochemistry, Institute of Biochemistry and Biophysics, University of Tehran, Tehran, Iran
    J Biomed Sci 16:31. 2009
    ..It is suggested higher binding affinity of mitoxantrone to chromatin compared to DNA implying that the histone proteins may play an important role in the chromatin- mitoxantrone interaction process...
  2. ncbi Interaction of mitoxantrone, as an anticancer drug, with chromatin proteins, core histones and H1, in solution
    Zahra Hajihassan
    Department of Biochemistry, Institute of Biochemistry and Biophysics, University of Tehran, Tehran, Iran
    Int J Biol Macromol 48:87-92. 2011
    ..The results suggest higher affinity of mitoxantrone to histone H1 compared to core histones providing histone proteins as a new target for mitoxantrone action at the chromatin level...
  3. ncbi The effect of vinca alkaloid anticancer drug, vinorelbine, on chromatin and histone proteins in solution
    Azra Rabbani-Chadegani
    Department of Biochemistry, Institute of Biochemistry and Biophysics, University of Tehran, Tehran, Iran
    Eur J Pharmacol 613:34-8. 2009
    ..The results for the first time suggest that apart from tubulins, chromatin components can also be considered as a new target for this anticancer drug...
  4. ncbi The effect of mitoxantrone as an anticancer drug on hepatocytes nuclei and chromatin: Selective release of histone proteins
    Zahra Hajihassan
    Department of Biochemistry, Institute of Biochemistry and Biophysics, University of Tehran, Tehran, Iran
    Indian J Pharmacol 43:187-91. 2011
    ..Mitoxantrone is an anticancer drug widely used in the treatment of various cancers. In the present study the effect of mitoxantrone on chromatin proteins of intact hepatocytes nuclei was investigated and compared with soluble chromatin...