Mohammad Reza Safarinejad

..We explored the efficacy of selenium and/or or N-acetyl-cysteine for improving semen parameters in infertile men, and the associations among semen quality and the concentrations of selenium and N-acetyl-cysteine in seminal plasma...

..The aim was to evaluate polyunsaturated fatty acid (PUFA) composition of the blood plasma and spermatozoa in infertile men with idiopathic oligoasthenoteratozoospermia (OAT)...

..We determined the efficacy of coenzyme Q10 supplementation on semen parameters, sperm function and reproductive hormone profiles in infertile men...

..To compare the efficacy of sustained-release (SR) bupropion to placebo in treating hypoactive sexual desire disorder (HSDD) in ovulating women...

..To evaluate the efficacy and safety of most selective serotonin reuptake inhibitor drug, escitalopram, in delaying ejaculation in patients with premature ejaculation (PE)...

..We present a framework for the evaluation, treatment, and follow-up of the male patient who presents with erectile dysfunction...

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..To evaluate the efficacy and safety of pindolol 7.5 mg/d in delaying of ejaculation in paroxetine-refractory patients...

..To evaluate the safety and efficacy of sildenafil citrate for treating erectile dysfunction (ED) in patients with combat-related post-traumatic stress disorder (PTSD)...

..To analyse the safety and efficacy of pentoxifylline sustained-release (PTX-SR) treatment in patients with early chronic Peyronie's disease (PD)...

..We hypothesized that genetic polymorphisms in methylenetetrahydrofolate reductase (MTHFR) gene are associated with prostate cancer risk...

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..In patients with organic anejaculation but without SCI midodrine can reverse anejaculation in more than 50% of patients. Further studies are needed, however, for the evaluation of different treatment regimens in anejaculation therapy...

..These parameters improved to their pre-exercise level during the recovery period. Long-term strenuous treadmill exercises (overtraining syndrome) have a deleterious effect on reproduction...

..It appears that the damage to HPT axis is both in pituitary and testicular levels. Further studies are needed to better elucidate the underlying pathophysiology of HPT axis dysregulation...

..44; 95% CI: 0.29-0.78, P=0.004). These results support the hypothesis of increased risk of GSTM1 or GSTT1null genotypes for developing infertility, but the nondeletion GSTM1 and GSTT1genotypes emerged as protective factors...

..To compare the efficacy and safety of dapoxetine, paroxetine, and placebo for the oral pharmacotherapy of premature ejaculation...

..To evaluate the natural background of prostate cancer in Iran a large population-based study of screening using total prostate-specific antigen (tPSA) and per cent free PSA (fPSA) as the initial test was performed...

..Further studies with different dosages and treatment regimens are necessary to draw final conclusions on the efficacy of this drug in PE and to prolong the efficacy...

..05) menopause status (P<or=0.01) and spousal erectile dysfunction (P=0.01) were significantly associated with FSD. This study provides a quantitative estimate of the prevalence and the main risk factors for FSD in Iranian women...

..Our data revealed a significant relationship between eNOS genotypes and the phenotype of infertility...

..To evaluate the efficacy and safety of a new serotonergic centrally acting drug tramadol in delaying ejaculation in patients with premature ejaculation...

..8 and 1.6 to 1.9 and 1.7, for tamsulosin and placebo, respectively (P=0.08). Mean number of adverse events was 11 for tamsulosin and 5 for placebo (P<0.05). Tamsulosin is no better than placebo in improvement of PE as a sole entity...

..4 vs 25.4, P=0.001). Mean per patient 'yes' responses to GEQ was 91.2 and 4.2% for sildenafil and saffron, respectively (P=0.0001). These findings do not support a beneficial effect of saffron administration in men with ED...

..001). Cabergoline is moderately effective salvage therapy for sildenafil nonresponse. Further studies with different dosages and treatment regimens are necessary to draw final conclusions on the efficacy of this drug in ED...

..To determine the effects of therapy with Urtica dioica for symptomatic relief of lower urinary tract symptoms (LUTS) secondary to benign prostatic hyperplasia (BPH)...

..Semen parameters and sperm DNA were evaluated in patients receiving selective serotonin reuptake inhibitors...

..To evaluate endocrine profile and hypothalamic-pituitary-testis (HPT) axis in male depressed patients with selective serotonin reuptake inhibitor (SSRI)-induced sexual dysfunction (SDF)...

..We evaluated the safety and efficacy of intranasal bremelanotide in men with erectile dysfunction who did not respond to sildenafil...

..We determined associations between 3 MTHFR gene polymorphisms (C677T, A1298C, and G1793A), serum folate, and total homocysteine (tHcy) levels, with male fertility status and semen parameters...

..To evaluate reproductive endocrine profile, sperm chromosomal abnormalities, and semen quality in patients with chronic hepatitis C...

..To investigate the association of the T-786C, G894T and variable number of tandem repeats (VNTRs) in intron 4 (a/b) polymorphisms of the eNOS gene in Iranian subjects with vasculogenic erectile dysfunction (ED)...

..Our aims were to evaluate reproductive hormones, hypothalamic-pituitary-ovarian axis, and fertility in female patients with hbeta-TM...

..03), and marital status (P = 0.01). The prevalence of BPH is relatively high in Iran. The provided bothersome due to BPH did not correlate to symptom severity and should be considered independently in clinical decision-making...

..Yet, further studies on the cause of primary and secondary infertility and geographical variations in the incidence and prevalence of infertility in Iran are needed...

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..If medical professionals want to prescribe herbal remedies for male infertility, previous rigorous scientific investigations, documenting their safety and efficacy are required...

..To determine the safety and efficacy of oral pentoxifylline (PTX) administration in improving semen parameters in infertile men with idiopathic OAT...

..We compared the efficacy and safety of oral vitamin E and propionyl-L-carnitine, separately or in combination, for the treatment of Peyronie's disease...

..We evaluated the safety and efficacy of sildenafil citrate for treating erectile dysfunction in patients with multiple sclerosis...

..Testicular biopsy showed selective atrophy of the germinal epithelium, intact Sertoli cells, and normal-appearing Leydig cells. CONCLUSIONS: Mustard gas can cause defective spermatogenesis years after exposure...

..Multicenter large scale studies are warranted to better elucidate the role of SHBG gene polymorphism in male infertility...

..Further studies are warranted in order to determine the incidence and prevalence of urolithiasis in different ethnic groups...

..The endocrine profile, hypothalamus-pituitary-testis axis and semen quality were evaluated in male patients with homozygous beta-thalassemia major...

..Sexual arousal disorder affects about 30% of women worldwide and there are no effective drug treatments for the disorder...

..However, there is a lack of evidence to show a clear clinical benefit of omega-3 in patients with PD...

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..The prevalence of chronic kidney disease (CKD) varies greatly between countries. In a community-based study, our aims were to determine the prevalence and associated risk factors of adult CKD in Iran...

..01). There was no significant correlation between serum levels of tHcy and folate and bladder cancer risk. Further studies in larger samples size and different ethnicity are required to confirm our findings...

..To investigate more effective chemotherapy against hormone refractory prostate cancer (HRPC) with the combination of estramustine (EM), docetaxel, and suramin...

..CONCLUSIONS: The results of our study indicate that subjects with SCI have an altered central neurotransmitter tone, and the likelihood of these abnormalities (hypogonadotropism) are higher in men with low thoracic SCI...

..Further investigation is needed to test the usefulness of long-term atorvastatin administration to restore erectile function in sildenafil nonresponders...

..71, 95% CI, 2.51-6.76 and OR 2.80, 95% CI, 1.47-4.32, respectively). This study provides a quantitative estimate of the prevalence and main risk factors for ED in Iranian men...

..10, P = 0.87). Genetic polymorphism of the IGFBP-3 gene may be involved in the etiology of bladder TCC, and our results need further confirmation by larger studies...

..We aimed to determine the subjective and objective outcomes of PR surgery in patients with arteriogenic ED...

..Endourology has allowed for a less-invasive approach to dealing with these transplant complications. Access to the upper urinary tract in traditionally anterior extravesical ureteroneocystostomy is usually difficult if not impossible...

..Our results reveal that OAB is a highly prevalent condition among Iranian women and that is has a serious impact on quality of life and sexual function...

..We evaluated the relationship between opium consumption and bladder cancer (BC) in a case-control study of an Iranian population...

..Exploring the hypothesis that "sexual function" is associated with mode of delivery is important, because sexual health is an integral part of general health...

..We determined the safety and efficacy of sorafenib in patients with castrate resistant prostate cancer (CRPC)...

..To assess the incidence of prostate adenocarcinoma in patients undergoing radical cystoprostatectomy due to bladder cancer in Iranian men...

..Colchicine is no better than placebo in improvement of pain, curvature angle, or plaque size in patients with Peyronie's disease...

..07). Mean number of adverse events was 32 for venlafaxine and 8 for placebo (P = 0.02). Venlafaxine is not better than placebo in treatment of PE...

..The objective of this review was to determine the efficacy, advantages and disadvantages of the most popular penile reconstruction (PR) and phallus construction techniques...

..To evaluate the frequency of prostatic involvement in pathologic samples of the patients who had undergone radical cystectomy due to transitional cell carcinoma (TCC) of the bladder...

..The surgical technique used for repair has been modified and refined. Our aim was to assess the effects of several interventions and management for amputated penis after replantation...

..To evaluate the efficacy and safety of tramadol in patients with idiopathic detrusor overactivity (IDO)...

..To determine the effectiveness and safety of high-dose isoxsuprine for the treatment of mixed-type erectile dysfunction...

..In conclusion, the eye is the organ most sensitive to sulfur mustard vapor. Ocular injuries generally heal completely. In severe cases, blindness may occur. The need for corneal transplantation is rare...