Simin Dadashzadeh

Summary

Affiliation: Shaheed Beheshti University of Medical Sciences
Country: Iran

Publications

  1. ncbi Time dependent pharmacokinetics of albendazole in human
    A Mirfazaelian
    Department of Pharmaceutics, Faculty of Pharmacy, Tehran University of Medical Sciences, PO Box 14155/6451, Tehran, Iran
    Biopharm Drug Dispos 24:199-204. 2003
  2. ncbi 9-nitrocamptothecin polymeric nanoparticles: cytotoxicity and pharmacokinetic studies of lactone and total forms of drug in rats
    Simin Dadashzadeh
    Department of Pharmaceutics, School of Pharmacy, Shaheed Beheshti Medical University, Tehran, Iran
    Anticancer Drugs 19:805-11. 2008
  3. ncbi Peritoneal retention of liposomes: Effects of lipid composition, PEG coating and liposome charge
    S Dadashzadeh
    Department of Pharmaceutics, School of Pharmacy, Shaheed Beheshti University of Medical Sciences, Tehran, Iran
    J Control Release 148:177-86. 2010
  4. ncbi The effect of gender on the pharmacokinetics of verapamil and norverapamil in human
    S Dadashzadeh
    Department of Pharmaceutics, Faculty of Pharmacy, Shaheed Beheshti University of Medical Sciences, Tehran, Iran
    Biopharm Drug Dispos 27:329-34. 2006
  5. ncbi The effect of PEG coating on in vitro cytotoxicity and in vivo disposition of topotecan loaded liposomes in rats
    S Dadashzadeh
    Department of Pharmaceutics, School of Pharmacy, Shaheed Beheshti Medical University, Tehran, Iran
    Int J Pharm 353:251-9. 2008
  6. ncbi 99mTc-HMPAO-labeled liposomes: an investigation into the effects of some formulation factors on labeling efficiency and in vitro stability
    Nila Mirahmadi
    Department of Pharmaceutics, School of Pharmacy, Shaheed Beheshti Medical University, P O Box 14155 6153, Tehran, Iran
    Nucl Med Biol 35:387-92. 2008
  7. ncbi Use of remote film loading methodology to entrap sirolimus into liposomes: preparation, characterization and in vivo efficacy for treatment of restenosis
    Azadeh Haeri
    Department of Pharmaceutics, School of Pharmacy, Shaheed Beheshti University of Medical Sciences, Tehran, Iran
    Int J Pharm 414:16-27. 2011
  8. ncbi Preparation and in vitro characterization of 9-nitrocamptothecin-loaded long circulating nanoparticles for delivery in cancer patients
    Katayoun Derakhshandeh
    Department of Pharmaceutics, Faculty of Pharmacy, University of Medical Science, Kermanshah 67145 1673, Iran
    Int J Nanomedicine 5:463-71. 2010
  9. ncbi Preparation, optimization, and characterization of topotecan loaded PEGylated liposomes using factorial design
    Amir Masoud Vali
    Department of Pharmaceutics, Shaheed Beheshti University of Medical Sciences, Tehran, Iran
    Drug Dev Ind Pharm 34:10-23. 2008
  10. ncbi PEGylated estradiol benzoate liposomes as a potential local vascular delivery system for treatment of restenosis
    Azadeh Haeri
    Department of Pharmaceutics, School of Pharmacy, Shaheed Beheshti University of Medical Sciences, Tehran, Iran
    J Microencapsul 29:83-94. 2012

Collaborators

  • Katayoun Derakhshandeh
  • Azadeh Haeri
  • A Mirfazaelian
  • Amir Masoud Vali
  • A M Vali
  • Saeed Sadeghian
  • Maryam Sotoudeh Anvari
  • Shahram Rabbani
  • N Mirahmadi
  • Farhad Mostafavi Shahab
  • Farzad Kobarfard
  • M R Rouini
  • Nila Mirahmadi
  • Mohammad Erfan
  • Mohammad Ali Boroumand
  • M H Babaei
  • Mohammad Hosein Babaei
  • Taiebeh Toliyat
  • Bijan Shafaghi
  • Fariba Johari Daha
  • B Shafaghi

Detail Information

Publications17

  1. ncbi Time dependent pharmacokinetics of albendazole in human
    A Mirfazaelian
    Department of Pharmaceutics, Faculty of Pharmacy, Tehran University of Medical Sciences, PO Box 14155/6451, Tehran, Iran
    Biopharm Drug Dispos 24:199-204. 2003
    ....
  2. ncbi 9-nitrocamptothecin polymeric nanoparticles: cytotoxicity and pharmacokinetic studies of lactone and total forms of drug in rats
    Simin Dadashzadeh
    Department of Pharmaceutics, School of Pharmacy, Shaheed Beheshti Medical University, Tehran, Iran
    Anticancer Drugs 19:805-11. 2008
    ....
  3. ncbi Peritoneal retention of liposomes: Effects of lipid composition, PEG coating and liposome charge
    S Dadashzadeh
    Department of Pharmaceutics, School of Pharmacy, Shaheed Beheshti University of Medical Sciences, Tehran, Iran
    J Control Release 148:177-86. 2010
    ..DOTAP/PEG100 may also be a more efficient formulation because this formulation can provide a high level of anticancer drug into the peritoneal cavity and also can passively target the primary tumor...
  4. ncbi The effect of gender on the pharmacokinetics of verapamil and norverapamil in human
    S Dadashzadeh
    Department of Pharmaceutics, Faculty of Pharmacy, Shaheed Beheshti University of Medical Sciences, Tehran, Iran
    Biopharm Drug Dispos 27:329-34. 2006
    ..A contribution of both factors in the appearance of gender differences in verapamil pharmacokinetics is also possible...
  5. ncbi The effect of PEG coating on in vitro cytotoxicity and in vivo disposition of topotecan loaded liposomes in rats
    S Dadashzadeh
    Department of Pharmaceutics, School of Pharmacy, Shaheed Beheshti Medical University, Tehran, Iran
    Int J Pharm 353:251-9. 2008
    ..PEGylated liposome resulted in a 52-fold and 2-fold increases in AUC(0-infinity) compared with that of free topotecan and CL, respectively. These results indicated that PEG modified liposome might be an effective carrier for topotecan...
  6. ncbi 99mTc-HMPAO-labeled liposomes: an investigation into the effects of some formulation factors on labeling efficiency and in vitro stability
    Nila Mirahmadi
    Department of Pharmaceutics, School of Pharmacy, Shaheed Beheshti Medical University, P O Box 14155 6153, Tehran, Iran
    Nucl Med Biol 35:387-92. 2008
    ....
  7. ncbi Use of remote film loading methodology to entrap sirolimus into liposomes: preparation, characterization and in vivo efficacy for treatment of restenosis
    Azadeh Haeri
    Department of Pharmaceutics, School of Pharmacy, Shaheed Beheshti University of Medical Sciences, Tehran, Iran
    Int J Pharm 414:16-27. 2011
    ..In vivo studies in balloon injured rat carotid arteries revealed the potential of SIR-loaded liposomes as efficient local and controlled drug delivery systems to reduce restenosis...
  8. ncbi Preparation and in vitro characterization of 9-nitrocamptothecin-loaded long circulating nanoparticles for delivery in cancer patients
    Katayoun Derakhshandeh
    Department of Pharmaceutics, Faculty of Pharmacy, University of Medical Science, Kermanshah 67145 1673, Iran
    Int J Nanomedicine 5:463-71. 2010
    ..These experimental results indicate that PLGA-PEG-NPs (versus PLGA-NPs) have a better physicochemical characterization and can be developed as a drug carrier in order to treat different malignancies...
  9. ncbi Preparation, optimization, and characterization of topotecan loaded PEGylated liposomes using factorial design
    Amir Masoud Vali
    Department of Pharmaceutics, Shaheed Beheshti University of Medical Sciences, Tehran, Iran
    Drug Dev Ind Pharm 34:10-23. 2008
    ..The prepared liposomes (especially PEGylated liposomes) as those described here may be clinically useful to stabilize and deliver topotecan for the treatment of cancer...
  10. ncbi PEGylated estradiol benzoate liposomes as a potential local vascular delivery system for treatment of restenosis
    Azadeh Haeri
    Department of Pharmaceutics, School of Pharmacy, Shaheed Beheshti University of Medical Sciences, Tehran, Iran
    J Microencapsul 29:83-94. 2012
    ..5:1:0.5 had the highest EE. In vivo studies in the balloon-injured rat carotid arteries revealed the potential of ESB-loaded liposomes as efficient local and controlled drug delivery systems to reduce restenosis...
  11. ncbi Simultaneous determination of a new antituberculosis agent KBF-611 and its de-acetylated metabolite in mouse and rabbit plasma by HPLC
    Farhad Mostafavi Shahab
    Biopharmacy and Pharmacokinetic Division, Department of Pharmaceutics, School of Pharmacy, Shaheed Beheshti Medical University, Tehran, Iran
    Arch Pharm Res 32:1453-60. 2009
    ..8% and 75.0% for KBF-611 and KM respectively. The established HPLC method was validated to be a simple, rapid and reliable procedure and successfully applied to study the preclinical pharmacokinetics of KBF-611 and KM in mice and rabbits...
  12. ncbi Simple and sensitive high performance liquid chromatographic method for the simultaneous quantitation of the lactone and carboxylate forms of topotecan in human plasma
    A M Vali
    Department of Pharmaceutics, School of Pharmacy, Shaheed Beheshti University of Medical Sciences, No. 105, Shams Alley, Across from Tavaneer Avenue, Vali-e-Asr Avenue, P.O. Box 14155-6153, Tehran, Iran
    J Chromatogr B Analyt Technol Biomed Life Sci 818:205-12. 2005
    ..The limit of quantitation was 0.05 ng/ml using 0.50 ml plasma. Stability studies in plasma and plasma extract indicated that topotecan is stable for at least 2 weeks at -70 degrees C...
  13. ncbi Effect of gender in the disposition of albendazole metabolites in humans
    A Mirfazaelian
    Biopharmaceutics Lab, Division of Pharmacokinetics, Department of Pharmaceutics, Faculty of Pharmacy, Tehran University of Medical Sciences, P.O.Box 14155/6451, Tehran, Iran
    Eur J Clin Pharmacol 58:403-8. 2002
    ....
  14. ncbi Liquid chromatographic quantitation of the lactone and the total of lactone and carboxylate forms of 9-nitrocamptothecin in human plasma
    K Derakhshandeh
    School of Pharmacy, Shaheed Beheshti University of Medical Sciences, No. 105, Shams Alley, across from Tavaneer Ave, Vali-E-Asr Ave, P.O. Box 14155-6153, Tehran, Iran
    J Chromatogr B Analyt Technol Biomed Life Sci 818:199-204. 2005
    ..5% in the concentration range of interest. The reported assay method showed good characteristics of linearity, sensitivity, selectivity and precision allowing applying in pharmacokinetic studies...
  15. ncbi Effect of liposome size on peritoneal retention and organ distribution after intraperitoneal injection in mice
    N Mirahmadi
    Department of Pharmaceutics, School of Pharmacy, Shaheed Beheshti Medical Sciences University, Tehran, Iran
    Int J Pharm 383:7-13. 2010
    ..Overall, among the different sized neutral liposomes investigated, the 1000 nm vesicles seemed to be the most optimal, achieving a greater peritoneal level and retention...
  16. ncbi Dose dependent pharmacokinetics of albendazole in human
    A Mirfazaelian
    Department of Pharmaceutics, Faculty of Pharmacy, Tehran University of Medical Sciences, P.O. Box 14155/6451, Tehran, Iran
    Biopharm Drug Dispos 23:379-83. 2002
    ....
  17. ncbi Dose dependent pharmacokinetics of theophylline: Michaelis-Menten parameters for its major metabolic pathways
    S Dadashzadeh
    Biopharmacy Division, Faculty of Pharmacy, Shaheed Beheshti University of Medical Sciences, Tehran-Iran
    Eur J Drug Metab Pharmacokinet 26:77-83. 2001
    ..In contrast to previous studies we didn't find obvious indication for nonlinear formation of DMU at therapeutic concentration range...