Research Topics
| Sunit K SinghSummaryAffiliation: Centre for Cellular and Molecular Biology Country: India Publications
| Collaborators
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Detail Information
Publications
Endogenous retroviruses: suspects in the disease worldSunit Kumar Singh
Center for Cellular and Molecular Biology, Section of Infectious Diseases, Hyderabad, India
Future Microbiol 2:269-75. 2007..Along with their expression in many disease conditions, they have also been reported to be expressed on normal peripheral blood lymphocytes, salivary glands and keratinocytes...
miRNAs: from neurogeneration to neurodegenerationSunit Kumar Singh
Center for Cellular and Molecular Biology, Section of Infectious Diseases and Functional Genomics, Uppal Road, Hyderabad 500007, India
Pharmacogenomics 8:971-8. 2007..This suggests a potential role of miRNAs in neurodevelopment of mammals and other organisms. In this review, I have focused on the role of miRNAs in brain development and possible neurological disorders...
RNA interference and its therapeutic potential against HIV infectionSunit K Singh
Centre for Cellular and Molecular Biology, Section of Infectious Diseases and Immunobiology, Room No S107, South Wing Ground Floor, Uppal Road, Hyderabad 500007, AP, India
Expert Opin Biol Ther 8:449-61. 2008..RNA interference (RNAi) has great potential to work as a powerful tool against HIV infection. Therefore, the possibilities of use of siRNA (small-interfering RNA) as a tool to deal with HIV infection are discussed in this article...
MicroRNAs--micro in size but macro in functionSunit K Singh
Section of Infectious Diseases and Immunobiology, Centre for Cellular and Molecular Biology, Hyderabad, India
FEBS J 275:4929-44. 2008..In this article, we have focused on the mechanism of miRNA biogenesis and the role of miRNAs in human health and disease...
siRNAs: their potential as therapeutic agents--Part II. Methods of deliverySunit Kumar Singh
Section of Infectious Diseases and Immunobiology, Centre for Cellular and Molecular Biology, Uppal Road, Hyderabad 500007, AP, India
Drug Discov Today 14:859-65. 2009..If these challenges associated with siRNA can be met, then the potentials of RNAi could be exploited to the full for the development of therapeutic tools and drugs...
Progress towards therapeutic application of RNA interference for HIV infectionSunit K Singh
Infectious Diseases and Immunobiology Group, Centre for Cellular and Molecular Biology, Hyderabad, Andhra Pradesh, India
BioDrugs 23:269-76. 2009..siRNAs are showing enormous potential to be used as a therapeutic tool in various diseases; however, this technology still requires refinement before its full potential can be utilized for the development of HIV therapies...
Japanese encephalitis virus: from genome to infectomeSalini Krishnan Unni
Laboratory of Neurovirology and Inflammation Biology, Section of Infectious Diseases, Centre for Cellular and Molecular Biology CCMB, Council of Scientific and Industrial Research CSIR, Uppal Road, Hyderabad, 500007 A P, India
Microbes Infect 13:312-21. 2011..Though, vaccines are currently available against JEV, it has to be further improved. Here we review the literature on the JEV life cycle, pathogenesis and host immune responses to JEV infection...
siRNAs: their potential as therapeutic agents--Part I. Designing of siRNAsPraveensingh B Hajeri
Section of Infectious Diseases and Immunobiology, Centre for Cellular and Molecular Biology, Uppal Road, Hyderabad 500007, AP, India
Drug Discov Today 14:851-8. 2009..In this review we have discussed the strategies and parameters required for effective siRNA designing and synthesis, based on already published literature...
Tits and bits of HIV Tat proteinManish K Johri
Laboratory of Neurovirology and Inflammation Biology, Section of Infectious Diseases, Centre for Cellular and Molecular Biology, Council of Scientific and Industrial Research, Uppal Road, Hyderabad 500007, A P, India
Expert Opin Biol Ther 11:269-83. 2011..This explains the massive death of immune cells due to bystander effect of HIV Tat protein among HIV-infected patients...
HIV/AIDS spread among womenSunit Kumar Singh
Expert Rev Anti Infect Ther 5:755-8. 2007
