Olafur Andri Stefansson

Summary

Affiliation: University of Iceland

Country: Iceland

Genomic profiling of breast tumours in relation to BRCA abnormalities and phenotypes
Olafur Andri Stefansson
Faculty of Medicine, University of Iceland, Vatnsmyrarvegur 16, Reykjavik, Iceland
Breast Cancer Res 11:R47. 2009
CpG island hypermethylation of BRCA1 and loss of pRb as co-occurring events in basal/triple-negative breast cancer
Olafur Andri Stefansson
Cancer Research Laboratory, Faculty of Medicine, University of Iceland, Reykjavik, Iceland
Epigenetics 6:638-49. 2011
Tetraploidy in BRCA2 breast tumours
Asta Björk Jonsdottir
Cancer Research Laboratory, Faculty of Medicine, University of Iceland, Reykjavik, Iceland
Eur J Cancer 48:305-10. 2012

Genomic profiling of breast tumours in relation to BRCA abnormalities and phenotypes
Olafur Andri Stefansson
Faculty of Medicine, University of Iceland, Vatnsmyrarvegur 16, Reykjavik, Iceland
Breast Cancer Res 11:R47. 2009
..Somatic mutations in BRCA1 and BRCA2 have not been found and the involvement of these genes in sporadic tumour development therefore remains unclear...
CpG island hypermethylation of BRCA1 and loss of pRb as co-occurring events in basal/triple-negative breast cancer
Olafur Andri Stefansson
Cancer Research Laboratory, Faculty of Medicine, University of Iceland, Reykjavik, Iceland
Epigenetics 6:638-49. 2011
..The clinical implications relate to the potential use of targeted treatment based on PARP inhibitors in sporadic TNBCs, wherein CpG island hypermethylation of BRCA1 represents a potential marker of therapeutic response...
Tetraploidy in BRCA2 breast tumours
Asta Björk Jonsdottir
Cancer Research Laboratory, Faculty of Medicine, University of Iceland, Reykjavik, Iceland
Eur J Cancer 48:305-10. 2012
..Additionally, tetraploidy emerges predominantly in BRCA2 breast cancers displaying luminal rather than triple-negative phenotypes...