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Genomes and GenesSpecies | Istvan WittmannSummaryCountry: Hungary Publications
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Publications
Single dose of acetylsalicylic acid in patients with Type 2 diabetes mellitus and/or chronic renal failure ameliorates anaemia by decreasing the rate of neocytolysisI Wittmann
Second Department of Medicine and Nephrological Center, Faculty of Medicine, University of Pecs, Pacsirta u 1, H 7624 Pecs, Hungary
Acta Physiol Hung 94:159-66. 2007..Aims of this study were to detect EPO resistance in patients with DM and/or CRF and to prove, that acetylsalicylic acid (ASA) is able to improve the haemopoietic status by decreasing neocytolysis...- [Decreased first-phase secretion of insulin may play a role in the development of insulin resistance]Istvan Wittmann
Pecsi Tudomanyegyetem Altalanos Orvostudomanyi Kar, II Belgyógyászati Klinika és Nephrologiai Centrum, Pecs
Orv Hetil 145:2267-72. 2004..On the basis of these data arises the possibility of the change of the attitude "Oh no, not insulin in type 2 diabetes" to the "early rapid-acting insulin analogue treatment" of these patients... - Prevention and treatment of diabetic nephropathyIstvan Wittmann
Second Department of Medicine and Nephrological Center, Faculty of Medicine, University of Pecs, H 7624 Pecs, Pacsirta u 1, Hungary
Diabetes Res Clin Pract 68:S36-42. 2005..Improvement of carbohydrate metabolism with a consequential decrease in the formation of AGE is an important contributor to the prevention and treatment of diabetic nephropathy and atherosclerosis... - Effects of pentoxifylline and pentosan polysulphate combination therapy on diabetic neuropathy in type 2 diabetes mellitusBoglarka Laczy
Second Department of Medicine and Nephrological Center, Faculty of Medicine, University of Pecs, Pacsirta u 1, 7624, Pecs, Hungary
Acta Diabetol 46:105-11. 2009..In conclusion, short-term PF-PPS therapy was effective on cardiovascular autonomic function and vibration perception, whereas it failed to reduce albuminuria within normal range in type 2 diabetic patients... - Resveratrol improves insulin sensitivity, reduces oxidative stress and activates the Akt pathway in type 2 diabetic patientsPál Brasnyó
2nd Department of Internal Medicine and Nephrological Center, Faculty of Medicine, University of Pecs, Pacsirta Street 1, Pecs H 7624, Hungary
Br J Nutr 106:383-9. 2011.... - Potential urinary biomarkers of disease activity in Crohn's diseaseLajos Markó
2nd Department of Medicine and Nephrological Center, University of Pecs, Faculty of Medicine, Pecs, Hungary
Scand J Gastroenterol 45:1440-8. 2010..The surprising results led us to perform measurements in greater depth... - Different effect of IgA nephropathy and polycystic kidney disease on arterial stiffnessIstván Késoi
Nephrology Center and 2nd Department of Internal Medicine, University of Pecs, 1 Pacsirta St, Pecs, Hungary
Kidney Blood Press Res 34:158-66. 2011..Renal function is a major predictor of vascular function and cardiovascular diseases. Little information exists about the effect of specific renal diseases on vascular function in chronic kidney diseases (CKD)... - Accumulation of renin and imidazolone in peritubular capillary endothelial cells in insulin-resistant hypertensive ratsZoltan Wagner
Second Department of Medicine and Nephrological Center, University of Pecs, Pacsirta Street 1, Pecs, Hungary
J Nephrol 24:656-64. 2011..The aim of our study was to investigate renal histology in rats with hypertension and IGT, with special emphasis on the peritubular endothelium... - Use of fullerene-, octadecyl-, and triaconthyl silica for solid phase extraction of tryptic peptides obtained from unmodified and in vitro glycated human serum albumin and fibrinogenKatalin Böddi
Department of Biochemistry and Medical Chemistry, University of Pecs, Pecs, Hungary
J Sep Sci 32:295-308. 2009..For HSA, ten new sites of glycation at lysine and arginine residues have been explored. Using the detailed SPE/off-line MALDI method the glycation sites on fibrinogen are first described in this paper... - Measurement of the modification and interference rate of urinary albumin detected by size-exclusion HPLCLajos Markó
2nd Department of Medicine and Nephrological Center, Faculty of Medicine, University of Pecs, Pecs, Hungary
Physiol Meas 30:1137-50. 2009..The interference rate of the albumin peak was found to be 12.7% on average, which does not explain the difference between the two methods... - Evidence of O-linked N-acetylglucosamine in diabetic nephropathyPeter Degrell
2nd Department of Medicine and Nephrological Center, University of Pecs, Hungary
Life Sci 84:389-93. 2009.... - Histological diagnosis determines complications of percutaneous renal biopsy: a single-center experience in 353 patientsViktória Fisi
Second Department of Medicine and Nephrological Center, University of Pecs, Pecs, Hungary
Kidney Blood Press Res 35:26-34. 2012..We studied the connection between complication occurrence related to renal biopsies and histological diagnoses of the biopsy specimen. We also analyzed the distribution of diagnoses in our population... - Effects of mono- and dual blockade of the renin-angiotensin system on markers of cardiovascular status in hypertensive patients with mild and moderate renal failureGabor Nagy
2nd Department of Medicine and Nephrological Center, Faculty of Medicine, University of Pecs, 1 Pacsirta St, Pecs, Hungary
Kidney Blood Press Res 34:150-7. 2011..Dual renin-angiotensin system (RAS) blockade has no more efficiency to decrease cardiovascular mortality than mono-blockade. Our goal was to explore differences between other cardiovascular markers in patients with RAS blockade... - Serum carboxymethyllysine predicts mortality in hemodialysis patientsZoltan Wagner
Second Department of Medicine, Nephrological Center, University of Pecs, Pecs, Germany
Am J Kidney Dis 47:294-300. 2006..The aim of the present study is to test whether serum level of the AGE carboxymethyllysine (CML) predicts all-cause or cardiovascular mortality in hemodialysis patients... - Serum total LDH activity and LDH-2 isozyme in nephrotic syndromeMárton Mohás
2nd Department of Medicine and Nephrological Center, Faculty of Medicine, University of Pecs, Pecs, Hungary
Kidney Blood Press Res 31:47-54. 2008..Proteinuria, hypoproteinaemia, hypoalbuminaemia and oedema are major characteristics of nephrotic syndrome. Aims of this study were to detect serum total LDH activity and its isozymes in nephrotic syndrome... - GCKR gene functional variants in type 2 diabetes and metabolic syndrome: do the rare variants associate with increased carotid intima-media thickness?Márton Mohás
2nd Department of Medicine and Nephrological Center, University of Pecs, Pecs, Hungary
Cardiovasc Diabetol 9:79. 2010.... - Storage at -80 degrees C decreases the concentration of HPLC-detected urinary albumin: possible mechanisms and implicationsLajos Markó
Second Department of Medicine and Nephrology Center, University of Pecs, Faculty of Medicine, Pécs Hungary
J Nephrol 22:397-402. 2009..We aimed to measure changes in HPLC-detected albuminuria after 2.5 years and find the factors which may be responsible for this alteration... - [Early anemia in diabetic nephropathy]Judit Nagy
Pecsi Tudomanyegyetem, Általános Orvostudományi Kar, II Belgyógyászati Klinika és Nephrologiai Centrum, Pecs
Orv Hetil 146:397-401. 2005.... - Cigarette smoke elicits relaxation of renal arteriesRichárd Halmai
2nd Department of Internal Medicine and Nephrology Center, University of Pecs, Pecs, Hungary
Eur J Clin Invest 41:195-202. 2011..Epidemiological studies suggest that cigarette smoking - probably by eliciting hyperperfusion - increases glomerular filtration rate; thus, we hypothesized that cigarette smoke affects the vasomotor tone of renal arteries... - Heart rate recovery after exercise is associated with renal function in patients with a homogenous chronic renal diseaseIstván Késoi
Nephrology Center and 2nd Department of Internal Medicine, Medical Faculty, University of Pecs, Hungary
Nephrol Dial Transplant 25:509-13. 2010..Diminished renal function is a similar predictor. There are no data concerning the interaction between the two risk factors. We studied HRR in patients with a homogeneous renal disease, IgA nephropathy... - Response of asymmetric dimethylarginine to hemodialysis-associated hypotension in end-stage renal disease patientsBotond Csiky
FMC Dialysis Center Pécs, Pecs, Hungary
Nephron Clin Pract 108:c127-34. 2008..To define the role of asymmetric dimethylarginine (ADMA) in the control of blood pressure (BP) during hemodialysis (HD)... - [Effect of ACE gene polymorphism on carbohydrate metabolism, on oxidative stress and on end-organ damage in type-2 diabetes mellitus]Gergo Attila Molnár
Pecsi Tudomanyegyetem, Általános Orvostudományi Kar, II Belgyógyászati Klinika és Nephrologiai Centrum
Orv Hetil 145:855-9. 2004..Endothelial damage may explain that these patients take a higher number of antihypertensive combination. Based on this, D allele may contribute--via increased glycation and oxidative stress--to the target organ damage in type 2 diabetes... - [Importance of hereditary haemochromatosis in the care of diabetes mellitus]Istvan Wittmann
Általános Orvostudományi Kar, II Belgyógyászati Klinika és Nephrologiai Centrum
Orv Hetil 148:111-5. 2007..A therapy-resistant state caused by the hereditary haemochromatosis may be found in diabetes mellitus and hypertension... - Enrichment of Amadori products derived from the nonenzymatic glycation of proteins using microscale boronate affinity chromatographyAnikó Takátsy
Department of Biochemistry and Medical Chemistry, University of Pecs, 7624 Pecs, Hungary
Anal Biochem 393:8-22. 2009..A peptide with a mass of 1783.9 Da could be detected only in samples of diabetic patients and, therefore, could be a very interesting biomarker candidate... - [Acute renal failure caused by plant extract]Katalin Vágási
Pecsi Tudomanyegyetem, Altalános Orvostudományi Kar II Belgyógyászati Klinika és Nephrológiai Centrum, Pecs, Hungary
Orv Hetil 148:421-4. 2007.... - Microalbuminuria, indicated by total versus immunoreactive urinary albumins, in acute ischemic stroke patientsPeter Toth
Department of Physiology, New York Medical College, Valhalla, New York, USA
J Stroke Cerebrovasc Dis 20:510-6. 2011..Future studies should aim to elucidate the underlying mechanisms for the relationship among urinary albumins and cerebrovascular diseases and the role of urinary albumins in risk stratification for stroke... - An approach to in situ detection of hydrogen peroxide: application of a commercial needle-type electrodeMonika Tamasko
Second Department of Medicine and Nephrological Center, Faculty of Medicine, University of Pecs, Pacsirta u 1, H 7624 Pecs, Hungary
Physiol Meas 28:1533-42. 2007.... - Apolipoprotein A5 IVS3+476A allelic variant associates with increased trigliceride levels and confers risk for development of metabolic syndrome in HungariansPeter Kisfali
Department of Medical Genetics and Child Development, University of Pecs, Pecs, Hungary
Circ J 72:40-3. 2008..Because other naturally occurring variants of the gene also correlate with elevated triglycerides, the possible role of 2 common variants, the IVS3+G476A and T1259C, with metabolic syndrome was investigated... - [The first case of single pancreas transplantation in Hungary]Peter Szakaly
Pecsi Tudomanyegyetem, Orvostudományi és Egészségtudományi Koordinációs Központ, Általános Orvostudományi Kar, Sebészeti Klinika, Pecs, Hungary
Orv Hetil 149:387-91. 2008..Conclusion: PTA transplant is a routinely used therapeutic option with good survival rate and good quality of life for type I diabetes mellitus patients without end stage renal disease... - Apolipoprotein A5 T-1131C variant confers risk for metabolic syndromeAnita Maasz
Department of Medical Genetics and Child Development, University of Pecs, Pecs, Hungary
Pathol Oncol Res 13:243-7. 2007..622 (1.200-10.936), p=0.02. Our findings strongly suggest that this variant is a risk factor for the development of hypertriglyceridemia and metabolic syndrome... - Pivotal role of Akt activation in mitochondrial protection and cell survival by poly(ADP-ribose)polymerase-1 inhibition in oxidative stressAntal Tapodi
Department of Biochemistry and Medical Chemistry, Faculty of Medicine, University of Pecs, Hungary
J Biol Chem 280:35767-75. 2005.... - Microalbuminuria in inflammatory bowel diseases using immunoturbidimetry and high-performance liquid chromatographyN Szigeti
2nd Department of Medicine and Nephrological Center, University of Pecs, Faculty of Medicine, Pecs, Hungary
Acta Gastroenterol Belg 72:394-401. 2009..To measure urinary albumin excretion using immunoturbidimetry (IT) and high-performance liquid chromatography (HPLC) in inflammatory bowel diseases... - A polymorphism within the fructosamine-3-kinase gene is associated with HbA1c Levels and the onset of type 2 diabetes mellitusM Mohas
Department of Medicine and Nephrological Center, University of Pecs, Hungary
Exp Clin Endocrinol Diabetes 118:209-12. 2010..Recently, the G900C (rs1056534) single nucleotide polymorpism (SNP) of the FN3K gene was found to be associated with the enzyme activity... - N(epsilon)-(carboxymethyl)lysine levels in patients with type 2 diabetes: role of renal functionZ Wagner
Second Department of Medicine and Nephrological Center, University of Pecs, Pecs, Hungary
Am J Kidney Dis 38:785-91. 2001..We conclude that the decline in renal function leads to increased serum AGE levels in patients with type 2 diabetes...