Research Topics
| Katalin SasSummaryAffiliation: University of Szeged Country: Hungary Publications
| Collaborators
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Detail Information
Publications
Effect of systemic administration of L-kynurenine on corticocerebral blood flow under normal and ischemic conditions of the brain in conscious rabbitsKatalin Sas
Department of Neurology, Albert Szent Gyorgyi Medical Centre, University of Szeged, Szeged, Hungary
J Cardiovasc Pharmacol 42:403-9. 2003..It is suggested that the cCBF-increasing effect of l-KYN might be mediated by activation of cholinergic and nitric oxide pathways...
Kynurenine diminishes the ischemia-induced histological and electrophysiological deficits in the rat hippocampusKatalin Sas
Department of Neurology, University of Szeged, Szeged, Hungary
Neurobiol Dis 32:302-8. 2008..It is concluded that the administration of KYN elevates the KYNA concentration in the brain to neuroprotective levels, suggesting its potential clinical usefulness for the prevention of neuronal loss in neurodegenerative diseases...
The pentylenetetrazole-induced activity in the hippocampus can be inhibited by the conversion of L-kynurenine to kynurenic acid: an in vitro studyEva Rozsa
Department of Physiology, Anatomy and Neuroscience, University of Szeged, POB 533, H 6701 Szeged, Hungary
Brain Res Bull 76:474-9. 2008....
Neuroprotection achieved in the ischaemic rat cortex with L-kynurenine sulphateHermina Robotka
Department of Physiology, Anatomy and Neuroscience, University of Szeged, POB 533, H 6701 Szeged, Hungary
Life Sci 82:915-9. 2008..This is the first histological proof of the neuroprotective effect achieved by the post-traumatic administration of L-kynurenine in the global ischaemic cortex...
Mitochondria, metabolic disturbances, oxidative stress and the kynurenine system, with focus on neurodegenerative disordersKatalin Sas
Department of Neurology, University of Szeged, POB 427, H 6701 Szeged, Hungary
J Neurol Sci 257:221-39. 2007..The last part of the review discusses metabolic disturbances and changes in the kynurenine metabolic pathway in Parkinson's, Alzheimer's and Huntington's diseases...
[Amnesic syndrome following lesion of the fornix or does reversible Korsakow's syndrome exist?]Réka Szakács
Szegedi Tudományegyetem Altalános Orvostudományi Kar, Pszichiatriai Klinika, Szeged
Neuropsychopharmacol Hung 9:39-43. 2007..Gradual, but continuous improvement of memory and cognitive function could be detected, with total recovery after one year. The deficits in long- and short-term memory, orientation and cognition were totally restored...
Favorable early outcome of carotid artery stenting without protection devicesLaszlo K Sztriha
Department of Neurology, Albert Szent Gyorgyi Medical and Pharmaceutical Center, University of Szeged, Semmelweis u 6, H 6725 Szeged, Hungary
Stroke 35:2862-6. 2004..We set out to investigate the complication rates associated with carotid artery stenting performed without protection devices. Applicability of covered stents in the carotid system was also evaluated...
Dementia, stroke and migraine--some common pathological mechanismsKatalin Sas
Department of Neurology, University of Szeged, H 6725 Szeged, Semmelweis u 6, Hungary
J Neurol Sci 299:55-65. 2010..This review surveys the most important features of the pathogenesis of dementia, stroke and migraine from the aspect of mitochondrial malfunction highlighting some of the considerable connections between these neurological disorders...
Hippocampal (CA1) activities in Wistar rats from different vendors. Fundamental differences in acute ischemiaMate Marosi
Department of Comparative Physiology, University of Szeged, H 6726 Szeged, Közép fasor 52, Hungary
J Neurosci Methods 156:231-5. 2006..These observations draw attention to the importance of the careful choice of the laboratory rats (both strains and breeds) used in such experiments...
Neuroprotective effect of L-kynurenine sulfate administered before focal cerebral ischemia in mice and global cerebral ischemia in gerbilsGabor Gigler
Division of Preclinical Research, EGIS Pharmaceuticals Plc, Budapest, Hungary
Eur J Pharmacol 564:116-22. 2007..In conclusion, the administration of L-kynurenine can elevate the brain concentration of kynurenic acid to neuroprotective levels, suggesting the potential clinical usefulness of L-kynurenine for the prevention of neuronal loss...
