Research Topics
Genomes and GenesSpecies | Zoltan RihmerSummaryAffiliation: National Institute of Psychiatry and Neurology Country: Hungary Publications
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Publications
Drug-placebo difference: in antidepressant drug trials could be 50% greater than previously believedZoltan Rihmer
National Institute for Psychiatry and Neurology, Budapest, Hungary
Neuropsychopharmacol Hung 9:35-7. 2007..The drug-placebo differences in all antidepressant drug trials should be re-calculated...
Cigarette smoking and suicide attempts in psychiatric outpatients in HungaryZoltan Rihmer
Psychiatry No 3, National Institute for Psychiatry and Neurology, Huvosvolgyi ut 116, Budapest, 1021 Hungary
Neuropsychopharmacol Hung 9:63-7. 2007..Epidemiological and clinical studies have found a significant association between smoking and suicidal behaviour...
Suicide prevention strategies--a brief reviewZoltan Rihmer
Department of Psychiatry, National Institute for Psychiatry and Neurology, Budapest, Hungary
Neuropsychopharmacol Hung 6:195-9. 2004..This article reviews the most important biological and non-biological suicide prevention strategies...
Do antidepressants t(h)reat(en) depressives? Toward a clinically judicious formulation of the antidepressant-suicidality FDA advisory in light of declining national suicide statistics from many countriesZoltan Rihmer
National Institute for Psychiatry and Neurology, Budapest, Hungary
J Affect Disord 94:3-13. 2006..The fact of being in treatment with regular clinical follow-up appears beneficial as well...
Suicide behaviour of patients treated with antidepressantsZoltan Rihmer
National Institute for Psychiatry and Neurology, Budapest, Hungary
Neuropsychopharmacol Hung 8:13-6. 2006..The almost double frequency of suicidal behaviour of patients on antidepressants compared to patients on placebo; it is in sharp contrast with the 2-6 fold lower suicide risk of antidepressant treatment versus untreated patients...
[Creativity and mental illness]Zoltan Rihmer
Orszagos Pszichiatriai es Neurologiai Intezet, III, Pszichiátriai Osztály és Kedélybetegségek Szakambulanciája, Budapest, Hungary
Psychiatr Hung 21:288-94. 2006....
Suicide risk in mood disordersZoltan Rihmer
National Institute for Psychiatry and Neurology and Department of Psychiatry and Psychotherapy, Semmelweis Medical University, Budapest, Hungary
Curr Opin Psychiatry 20:17-22. 2007..The aim of this review is to highlight the traditional and newly recognized suicide risk factors in patients with mood disorders...
Interaction of 5-HTTLPR genotype and unipolar major depression in the emergence of aggressive/hostile traitsXenia Gonda
Department of Clinical and Theoretical Mental Health, Kutvolgyi Clinical Center, Semmelweis University, Budapest, Hungary
J Affect Disord 132:432-7. 2011..Our aim was to investigate the association between 5-HTTLPR and aggressive/hostile traits in depressed patients and controls...
[The role of childhood abuse in adult suicidal behaviour]Annamaria Rihmer
Semmelweis Egyetem, Pszichiatriai es Pszichoterapias Klinika, Budapest, Hungary
Neuropsychopharmacol Hung 11:237-46. 2009..However, regardless of gender, it was significantly more severe (p<0.01) among those who were victims of both physical and sexual childhood abuse...
The possible contributory role of the S allele of 5-HTTLPR in the emergence of suicidalityXenia Gonda
Department of Pharmacodynamics, Semmelweis University, Faculty of Medicine, Budapest, Hungary
J Psychopharmacol 25:857-66. 2011..This study aimed to integrate findings concerning possible endophenotypes modulating between genetic factors and manifested suicidal behaviour...
A study of affective temperaments in Hungary: internal consistency and concurrent validity of the TEMPS-A against the TCI and NEO-PI-RSandor Rozsa
Department of Personality and Health Psychology, Lorand Eotvos University, Budapest, Hungary
J Affect Disord 106:45-53. 2008..We were particularly interested in concurrent validation against the TCI and the NEO-PI-R, the most important of the new personality instruments...
Association of the s allele of the 5-HTTLPR with neuroticism-related traits and temperaments in a psychiatrically healthy populationXenia Gonda
Dept of Clinical and Theoretical Mental Health, Kutvolgyi Clinical Centre, Semmelweis University, Kutvolgyi ut 4, 1125, Budapest, Hungary
Eur Arch Psychiatry Clin Neurosci 259:106-13. 2009..The aim of our study was to investigate the association of the 5-HTTLPR polymorphism with several smaller, distinct and better characterisable phenomena related to the neuroticism trait...
High anxiety and migraine are associated with the s allele of the 5HTTLPR gene polymorphismXenia Gonda
Laboratory of Neurochemistry and Experimental Medicine, National Institute of Psychiatry and Neurology, Huvosvolgyi ut 116, H 1021 Budapest, Hungary
Psychiatry Res 149:261-6. 2007..The association of migraine with anxiety may be explained by the higher rate of individuals carrying the s allele among migraineurs...
Current research on affective temperamentsZoltan Rihmer
Department of Clinical and Theoretical Mental Health, Faculty of Medicine, Semmelweis University, Kutvolgyi ut 4, Budapest, Hungary
Curr Opin Psychiatry 23:12-8. 2010..The aim of this review is to highlight the relationship between affective temperaments and clinical mood disorders and to summarize the earlier and most recent studies on affective temperaments in both clinical and nonclinical populations...
Relationship between obsessive-compulsive symptoms and smoking habits amongst schizophrenic patientsPeter Dome
National Institute of Psychiatry and Neurology, Budapest, Hungary
Psychiatry Res 144:227-31. 2006..We found that the rates did not differ significantly, so we came to the conclusion that OC symptoms are not in a tight relationship with smoking habits among patients with SCH/SCHAFF...
[Etiopathology and therapy of seasonal affective disorder]Eszter Molnar
Gyógyszerhatástani Intézet, Semmelweis Egyetem, Gyógyszerésztudományi Kar, Budapest, Hungary
Neuropsychopharmacol Hung 12:483-94. 2010..In practice the most effective treatment for SAD is the combination of light therapy, antidepressants and psychotherapy...
[Diagnostic features, epidemiology, and pathophysiology of seasonal affective disorder]Eszter Molnar
Gyógyszerhatástani Intézet, Semmelweis Egyetem, Gyógyszerésztudományi Kar, Budapest, Hungary
Psychiatr Hung 25:407-16. 2010..Genetic studies focusing on candidate genes involve 5-HTR2A, 5-HTR2C, DRD4, G protein, and clock-related genes...
Season of birth is significantly associated with the risk of completed suicidePeter Dome
Department of Clinical and Theoretical Mental Health, Kutvolgyi Clinical Center, Semmelweis University, Faculty of Medicine, Budapest, Hungary
Biol Psychiatry 68:148-55. 2010..Previous studies have provided somewhat inconsistent results about the effects of season of birth on the risk of suicidal behavior. Therefore, we decided to investigate this question in a large sample of suicide completers...
Impact on suicidality of the borderline personality traits impulsivity and affective instabilityZoltan Rihmer
Department of Clinical and Theoretical Mental Health, Faculty of Medicine, Semmelweis University, Budapest, Hungary
Ann Clin Psychiatry 22:121-8. 2010..The aim of this study was to test the impact on suicidality (suicide threats, attempts) of the borderline personality disorder (BPD) traits impulsivity and affective instability in mood disorders...
Seasonality and winter-type seasonal depression are associated with the rs731779 polymorphism of the serotonin-2A receptor geneEszter Molnar
Department of Pharmacodynamics, Semmelweis University, Budapest, Hungary
Eur Neuropsychopharmacol 20:655-62. 2010..The fact that the above polymorphism showed association not only with clinical SAD but also seasonality symptoms in a general population provides evidence for the spectrum nature of this connection...
Risk factors for suicide in Hungary: a case-control studyKitty Almasi
In and Outpatient Department of Psychiatry, No III, National Institute for Psychiatry and Neurology, Budapest, Hungary
BMC Psychiatry 9:45. 2009..We hypothesised that suicide in Hungary would be associated with both risk factors for suicide as identified in Western studies, and experiences related to social and economic restructuring...
[The clinical importance of affective temperaments]Ajandek Eory
Semmelweis Egyetem Csaladorvosi Tanszek, Budapest, Hungary
Psychiatr Hung 26:144-57. 2011....
How possible is the development of an operational psychometric method to assess the presence of the 5-HTTLPR s allele? Equivocal preliminary findingsXenia Gonda
Department of Pharmacodynamics, Semmelweis University, Faculty of Medicine, Budapest, Hungary
Ann Gen Psychiatry 9:21. 2010..The aim of the current study was to develop a psychometric tool that could at least partially substitute for laboratory testing and could predict the presence of the s allele...
Gender differences in antidepressant use-related seasonality change in suicide mortality in Hungary, 1998-2006Beata Sebestyen
National Center for Healthcare Audit and Inspection, Budapest, Hungary
World J Biol Psychiatry 11:579-85. 2010..The aim of the present study was to analyse the relationship between increasing antidepressant utilization and national suicide rate of Hungary between 1998 and 2006, with particular regard to seasonal patterns and gender differences...
Suicide prevention programs through education in the frame of healthcareZoltan Rihmer
Department of Clinical and Theoretical Mental Health, Kutvolgyi Clinical Center, Semmelweis University, Budapest, Hungary
Psychiatr Hung 24:382-7. 2009..This paper summarizes the healthcare-based educational programmes that have been shown effective in reducing suicide morbidity and mortality even in this high-risk population...
Associations between season of birth and the risk of lung cancer: epidemiological findings from HungaryBalázs Kapitány
Demographic Research Institute of the Hungarian Central Statistical Office, Budapest, Hungary
Chronobiol Int 28:643-50. 2011..The possible associations between MOB and the risk of lung cancer development (or smoking) would require confirmation (or refutation) in large studies from other populations...
[Mood, mood fluctuations and depression: role of the circadian rhythms]Robert Bodizs
MTA BME Kognitív Tudományi Kutatócsoport, Budapest, Hungary
Neuropsychopharmacol Hung 12:277-87. 2010..Pharmacological approaches, lifestyle changes and specific chronotherapeutic interventions might help to achieve this goal...
[Antidepressive efficacy of quetiapine XR in unipolar major depression--the role of early onset of action and sleep-improving effect in decreasing suicide risk]Zoltan Rihmer
Semmelweis Egyetem, Kútvölgyi Klinikai Tömb, Klinikai es Kutatasi Mentalhigienes Osztaly, Budapest, Hungary
Neuropsychopharmacol Hung 11:211-5. 2009..Both beneficial effects play an important role in the reduction of suicidal risk frequently seen in depressed patients...
Is drug-placebo difference in short-term antidepressant drug trials on unipolar major depression much greater than previously believed?Zoltan Rihmer
Department of Clinical and Theoretical Mental Health, Semmelweis University, Faculty of Medicine, Budapest, Hungary
J Affect Disord 108:195-8. 2008....
[Economic recession, unemployment and suicide]Timea Duleba
Semmelweis Egyetem Kutvolgyi Klinikai Tomb, Klinikai es Kutatasi Mentalhigienes Osztaly, Budapest, Hungary
Neuropsychopharmacol Hung 14:41-50. 2012....
The role of hyperventilation: hypocapnia in the pathomechanism of panic disorderAndras Sikter
Department of Internal Medicine, St Rokus Hospital, Budapest, Hungary
Rev Bras Psiquiatr 29:375-9. 2007..The review presented attempts to integrate three premises: hyperventilation is a physiological response to hypercapnia; hyperventilation can induce panic attacks; chronic hyperventilation is a protective mechanism against panic attacks...
The 5HTTLPR polymorphism of the serotonin transporter gene is associated with affective temperaments as measured by TEMPS-AXenia Gonda
Laboratory of Neurochemistry and Experimental Medicine, National Institute for Psychiatry and Neurology, Budapest, Hungary
J Affect Disord 91:125-31. 2006....
The close link between suicide attempts and mixed (bipolar) depression: implications for suicide preventionJudit Balazs
Vadaskert Child Psychiatric Hospital and Outpatient Clinic, Budapest, Hungary
J Affect Disord 91:133-8. 2006..Previous reports have shown a significant relationship between suicide ideation and mixed depression. The aim of this study was to explore the prevalence and clinical characteristics of mixed depression among non-violent suicide attempters...
The effect of pharmacotherapy on suicide rates in bipolar patientsZoltan Rihmer
Department of Clinical and Theoretical Mental Health, Semmelweis University, Budapest, Hungary
CNS Neurosci Ther 18:238-42. 2012..In bipolar patients suicidal behavior is most likely to occur during pure or mixed depressive episodes. Since bipolar disorder is a highly recurrent illness, adequate long-term pharmacotherapy is needed to prevent suicidal behavior...
