Research Topics
Species | Orsolya TokeSummaryAffiliation: Chemical Research Center Country: Hungary Publications
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Detail Information
Publications
Solution structure of the all L- and D-amino acid-substituted mucin 2 epitope peptidesOrsolya Toke
Institute of Structural Chemistry, Chemical Research Center, Hungarian Academy of Sciences, 59 67 Pusztaszeri út, Budapest H 1025, Hungary
Biochem Biophys Res Commun 358:739-42. 2007....- A kinked antimicrobial peptide from Bombina maxima. I. Three-dimensional structure determined by NMR in membrane-mimicking environmentsOrsolya Toke
Institute of Structural Chemistry, Chemical Research Center of the Hungarian Academy of Sciences, 59 67 Pusztaszeri út, 1025 Budapest, Hungary
Eur Biophys J 40:447-62. 2011..As a first step in elucidating the membrane interactions of maximin-4, our study contributes to a better understanding of the mode of action of antimicrobial peptides and the factors governing their selectivity... - Folding transitions in calpain activator peptides studied by solution NMR spectroscopyOrsolya Toke
Institute of Structural Chemistry, Chemical Research Center, Hungarian Academy of Sciences, 59 67 Pusztaszeri út, Budapest, H 1025 Hungary
J Pept Sci 15:404-10. 2009..According to our data, the presence of Ca(2+) induces a backbone rearrangement in the peptides, an effect that may contribute to setting the fine conformational balance required for the interaction of the peptides with calpain... - Determinants of cooperativity and site selectivity in human ileal bile acid binding proteinOrsolya Toke
Department of Biochemistry and Molecular Biophysics, Washington University School of Medicine, St Louis, Missouri 63110, USA
Biochemistry 45:727-37. 2006..Possible communication pathways between the two binding sites are discussed... - Kinetic mechanism of ligand binding in human ileal bile acid binding protein as determined by stopped-flow fluorescence analysisOrsolya Toke
Department of Biochemistry and Molecular Biophysics, Washington University School of Medicine, St Louis, Missouri 63110, USA
Biochemistry 46:5427-36. 2007..Analogous to that in the intestinal fatty acid binding protein (I-FABP), we hypothesize that ligand binding in I-BABP is linked to a disorder-order transition between an open and a closed form of the protein... - Internal motions and exchange processes in human ileal bile acid binding protein as studied by backbone (15)N nuclear magnetic resonance spectroscopyGergo Horváth
Institute of Structural Chemistry, Chemical Research Center of the Hungarian Academy of Sciences, 59 67 Pusztaszeri út, Budapest, H 1025 Hungary
Biochemistry 51:1848-61. 2012..According to the NMR measurements, the helical cap region may have a less crucial role in mediating ligand entry and release than what has been indicated for fatty acid binding proteins... - Peptide antibiotics in action: investigation of polypeptide chains in insoluble environments by rotational-echo double resonanceOrsolya Toke
Institute for Structural Chemistry, Chemical Research Center of the Hungarian Academy of Sciences, , H-1025 Budapest, Hungary
Biochim Biophys Acta 1758:1314-29. 2006..In this review, we will present two applications of REDOR: the investigation of a magainin-related antimicrobial peptide in lipid bilayers and the study of a vancomycin-like glycopeptide in the cell walls of Staphylococcus aureus... - Chiral separation by a monofunctionalized cyclodextrin derivative: from selector to permethyl-beta-cyclodextrin bonded stationary phaseGabor Varga
ChiroQuest Chiral Technologies Development Ltd, Budapest, Hungary
J Pharm Biomed Anal 51:84-9. 2010..The development process was supported by CE experiments where the complex formation between cyclodextrins and warfarin was investigated. The results demonstrate good enantio-discrimination for coumarin derivatives... - Glutamate uptake triggers transporter-mediated GABA release from astrocytesLászló Héja
Department of Neurochemistry, Institute of Biomolecular Chemistry, Chemical Research Center, Hungarian Academy of Sciences, Budapest, Hungary
PLoS ONE 4:e7153. 2009.... - Antimicrobial peptides: new candidates in the fight against bacterial infectionsOrsolya Toke
Department of Biochemistry and Molecular Biophysics, Washington University School of Medicine, St Louis, MO 63110, USA
Biopolymers 80:717-35. 2005..The emphasis will be on linear AMPs but representatives of cysteine-bridged AMPs will also be discussed... - Structure of (KIAGKIA)3 aggregates in phospholipid bilayers by solid-state NMROrsolya Toke
Department of Chemistry, Washington University, St. Louis, Missouri 63130, USA
Biophys J 87:675-87. 2004..This result suggests that the K3 dimers detected by REDOR at L/P = 20 are not on the surface of the bilayer but are in a membrane pore... - Secondary structure and lipid contact of a peptide antibiotic in phospholipid bilayers by REDOROrsolya Toke
Department of Chemistry, Washington University, St. Louis, Missouri 63130, USA
Biophys J 87:662-74. 2004..Despite these distortions, static (31)P NMR lineshapes indicate that the lamellar structure of the membrane is preserved...