Hypoglycemic herbs and their action mechanismsHongxiang Hui
Department of Medicine, Veterans Affairs Greater Los Angeles Healthcare System, Los Angeles, 90073, USA
Chin Med 4:11. 2009
..The efficacy of hypoglycemic herbs is achieved by increasing insulin secretion, enhancing glucose uptake by adipose and muscle tissues, inhibiting glucose absorption from intestine and inhibiting glucose production from heptocytes...
Glucagon like peptide-1-directed human embryonic stem cells differentiation into insulin-producing cells via hedgehog, cAMP, and PI3K pathwaysHongxiang Hui
UCLA Center of Excellence in Pancreatic Disease, David Geffen School of Medicine at UCLA, Los Angeles, CA 90024 7073, USA
Pancreas 39:315-22. 2010
..That glucagonlike peptide-1 (GLP-1) induces differentiation of primate embryonic stem (ES) cells into insulin-producing cells has been reported by several groups and also confirmed with our observations...
The role of GLP-1 in the regulation of islet cell massAngela Bulotta
Division of Endocrinology, Diabetes and Metabolism, Department of Medicine, Cedars Sinai Medical Center, Los Angeles, CA, USA
Cell Biochem Biophys 40:65-78. 2004
..The aim of this article is to review those reports that have emphasized the role of GLP-1 as a regulator of islet cell mass as well as its insulin secretory action...
Structure and function studies of glucagon-like peptide-1 (GLP-1): the designing of a novel pharmacological agent for the treatment of diabetesHongxiang Hui
Division of Endocrinology and Metabolism, Cedars-Sinai Medical Center, Los Angeles, California 90048, USA
Diabetes Metab Res Rev 21:313-31. 2005
....
Direct spectrophotometric determination of serum fructose in pancreatic cancer patientsHongxiang Hui
Division of Endocrinology, David Geffen School of Medicine at UCLA, Department of Surgery, Cedars Sinai Medical Center, Los Angeles, CA 90024, USA
Pancreas 38:706-12. 2009
..We sought to develop an assay to measure circulating fructose concentrations in pancreatic cancer patients...
Pancreatic beta-cells expressing GLP-1 are resistant to the toxic effects of immunosuppressive drugsEugenio D'Amico
Division of Endocrinology, Cedars Sinai Medical Center, Los Angeles, California, USA
J Mol Endocrinol 34:377-90. 2005
..This report demonstrates that GLP-1 is capable of preserving beta-cell function and protecting cells from apoptotic cell death...
Intrasplenic transplantation of encapsulated genetically engineered mouse insulinoma cells reverses streptozotocin-induced diabetes in ratsTakeshi Aoki
Surgical Research, Department of Surgery, Cedars-Sinai Medical Center, David Geffen UCLA School of Medicine, Los Angeles, CA 90048, USA
Cell Transplant 14:411-21. 2005
..e., in a physiological manner)...
Murine pituitary tumor-transforming gene functions as a securin protein in insulin-secreting cellsRun Yu
UCLA School of Medicine, Cedars Sinai Research Institute, Cedars Sinai Medical Center, 8700 Beverly Blvd, Room D3066, Los Angeles, California 90048, USA
J Endocrinol 191:45-53. 2006
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The alpha1-adrenergic receptor antagonist doxazosin inhibits EGFR and NF-kappaB signalling to induce breast cancer cell apoptosisHongxiang Hui
Division of Endocrinology, David Geffen School of Medicine at University of California at Los Angeles, Los Angeles, CA 90024, USA
Eur J Cancer 44:160-6. 2008
..Doxazosin is proposed as a possible novel medical therapy for breast cancer...