Josep Maria Haro

..Antipsychotic maintenance in SOHO was higher than the results of previous randomized studies...

..Due to demographic change, the advanced elderly represent the fastest growing population group in Europe. Health problems tend to be frequent and increasing with age within this cohort...

..We also explored differential item functioning (DIF) in men and women...

..Evidence suggests that schizophrenia may have a better outcome for individuals living in low- and middle-income countries compared with affluent settings...

..This important information is likely to impact on the future use of antipsychotics and will assist clinicians in refining the use of these drugs and improving the outcome of patients to whom they are prescribed...

..Observational studies, when properly conducted and when using adequate statistical methods, can provide valid information on the evaluation of health technologies...

..Large observational studies may be useful in identifying variables that predict switch to depression after mania and provide data on medication use and outcomes in "real world" patients...

..To estimate the comorbidity of mental disorders with chronic physical conditions and to assess their independent and combined effects on health-related quality of life (HRQOL)...

..In conclusion, in this group of outpatients with schizophrenia, gender is a predictor of clinical response to antipsychotic treatment, but its influence is not the same for all antipsychotics...

..Antidepressants are supposed to be withdrawn during a manic episode. The aim of this study was to analyze the characteristics of manic patients who received antidepressants during a manic phase in a large, naturalistic study...

..In conclusion, treatment effectiveness and tolerability varied among antipsychotic medications in previously untreated patients with schizophrenia. The results should be interpreted conservatively given the observational study design...

..The aim of the present study is to compare suicide ideation among women in the pre-, peri-, and post-menopause using a cross-sectional household survey of non-institutionalised adults from six European countries...

..The World Health Organization (WHO) has stated that the three leading causes of burden of disease in 2030 are projected to include HIV/AIDS, unipolar depression and ischaemic heart disease...

..The results should be interpreted conservatively because of the observational, nonrandomized study design...

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..Factors that could be associated with adequacy of care also were explored...

..Women had a faster time to mania improvement and a higher risk of developing a depressive episode during the 12-month follow-up period...

..The prevalence of obsessive-compulsive symptom dimensions and their sociodemographic and psychopathological correlates at the population level are unknown...

..This could cause high levels of family burden. The objective of this study is to assess the relationship between the patients' needs and other clinical and disability variables and the level of family burden...

..Until now, MSMs have not been used to compare the effects of more than two treatments...

..The results from the SOHO study indicate that differences in effectiveness and tolerability do exist between the antipsychotics...

..There are few quality-of-life instruments specifically for schizophrenia; thus, the objective of our study is to adapt and validate the Satisfaction with Life Domains Scale (SLDS) by Baker and Intagliata...

..Previous cost-utility studies, comparing selective serotonin reuptake inhibitors and tricyclic antidepressants, have used modelling techniques or have not included indirect costs in the economic analyses...

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..CONCLUSIONS: CBP-CNP is highly prevalent and comorbid with other physical and mental conditions. Comorbidity negatively affects individuals global functioning...

..The present findings suggest that further investigation on the mediators between clinical and social outcomes may help to design specific treatments to reduce disability...

..The findings from this study should be interpreted conservatively because of its non-randomized observational design...

..This study aimed to describe the adequacy of treatment for Anxiety and Depressive disorders in Spain, how this differs between providers (primary versus specialised care) and which factors are associated with appropriate care...

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..Prescription of PSD is associated with clinical and non-clinical factors. Purpose. To describe the patterns of PSD prescribing over a 12-month period and to determine the factors associated with this in a PC population...

..We hypothesized that SP4 levels may be altered in the brain of bipolar disorder (BD) subjects and regulated by neuronal activity and drug treatment...

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..The results should be interpreted conservatively due to the observational design of SOHO...

..Symptomatic remission is an achievable goal of treatment in patients with schizophrenia...

..To determine the cost utility of treating schizophrenic patients with olanzapine compared with other antipsychotics in a naturalistic outpatient setting...

..The objective of this study was to describe clinical and work functional outcomes associated with 6-month open-label olanzapine treatment for bipolar I disorder...

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..Suicide is a public health problem and it is increasing in Spain. The objective of this study is to analyze the prevalence and risk factors of suicide related outcomes (ideation, plan and attempt) using data from the ESEMeD-Spain project...

..The purpose of this study was to describe mental health care in catchment health areas in Chile and Spain in order to complement information reported at the macro-level (countries or regions)...

..Differential treatment course and outcome after 12 weeks of treatment were examined for three distinct classes of patients with acute mania in bipolar disorder...

..To examine factors associated with the use of antidepressants (AD) and benzodiazepines (BZD) in 6 European countries...

..Patients who switched to olanzapine experienced a higher weight gain. In conclusion, among patients switching antipsychotic medication, those who switched to olanzapine had better long-term outcomes...

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..The results should be interpreted conservatively due to the observational study design...

..Suicide is a leading cause of death worldwide; however, the prevalence and risk factors for the immediate precursors to suicide - suicidal ideation, plans and attempts - are not wellknown, especially in low- and middle-income countries...